543 件 ・ 関連度順
概要と使いどころ
Measurement-driven code refactoring — profile before changing, measure after, keep only if metrics improve. Covers complexity reduction, extraction patterns, and bulk refactoring for mechanical changes across many files.
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Triage Linear or Jira backlogs and run bug sweeps via the Composio CLI. Bulk-fetch issues, deduplicate, relabel, reassign, and post summaries all from the shell.
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Export Twitter/X data to CSV for analysis using Xpoz. Search by keywords, author, date range, and download complete datasets (up to 500K rows). Use when asked to "export tweets", "download Twitter data", "get tweets as CSV", "Twitter dataset", or "bulk tweet download".
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Scan every open pull request in a GitHub repository, filter to the ones that are genuinely mergeable now, and report a compact verdict with a suggested merge order. Use when the user asks which PRs can be merged, wants an open-PR backlog triaged or reviewed in bulk, asks why a PR is blocked, or wants to clear a queue of stale or bot-reviewed PRs.
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分布式并行策略选型与实测（USP / CP 通信掩盖 / CFG / TP/RSP/PP 概览；含拓扑相关选型 （按实测拓扑分域条件化：域内 bulk vs 跨域 head-parallel 翻转）与 AlltoAllV 缺陷绕过）。在 model-auto-optimization 中承担 S3：优先 USP、结合拓扑带宽差异选 CP，少量 step + 多 rank 验证特性开启与掩盖（产物：并行方案 + 多 rank 证据）。当用户需要多卡并行 策略选择、**序列并行形态抉择**（纯 Ulysses vs 复合 AllGather-KV×Ulysses：按 GQA / 跨域带宽 / 形态 plumbing 条件化定胜负）、**并行 × 稀疏叠加**（seam 契约：先汇聚后稀疏、 窗口偏移、块对齐、per-head 掩码；含「稀疏看似生效实则未生效」判定）、通信掩盖调优 （含**掩盖率上限**：1-1/n 何时成立、c/f 决定的真实上限、没生效的排查）、**并行方案 差异归因**（阶段 Δ 分解 / 集合通信按 communicator 归属 / 4→8 卡线性度），或排查多卡 跑不动 / 通信暴露大 / 换卡组 / 端口 bind / HCCL 带宽验证问题时使用；**并收编原并行作用域诊断**： 改了 SP/CP/Ulysses/AllGather-KV 后**不报错但结果没变/性能没变**、或小规模能跑大规模崩 （如 Ascend EE1003 coreDim 超限）时，用本技能证明"改动到底有没有生效"（判别量逐层收窄 + 两侧对照 + 日志≠生效，见 `references/scope-effectiveness-check.md`）； 即使用户只说 "多卡跑不动""通信暴露大""为什么没达到 6/7 的掩盖率""CP 和 USP 该选哪个""CP 叠稀疏 怎么不生效"而未说并行，也应触发。特性档位/接口事实见 `docs/zh/features/parallelism.md` /`usp.md`（仓内真源），框架侧开启见 framework-integration； 本技能承载选型决策、monkey-patch 掩盖与多卡诊断实测。 由 dev-workflow 多卡场景触发，亦由 model-auto-optimization 的 S3 阶段触发。
日本語の概要は準備中です。原文の説明を表示しています。
Manage JIRA issue relationships via jira-as: link, unlink, blockers, dependencies, clone, bulk-link. NOT sprint/epic relationships (mk:jira-agile).
日本語の概要は準備中です。原文の説明を表示しています。
JIRA time tracking via jira-as: log work, worklogs, estimates, reports, bulk-log. Edit/delete confirms first (data loss). NOT sprint capacity (mk:jira-agile).
日本語の概要は準備中です。原文の説明を表示しています。
Manage JIRA issue relationships via the jira-as wrapper: link, unlink, blockers, dependencies, clone, bulk-link. Triggers: 'link KEY blocks KEY', 'what blocks KEY', 'clone KEY', 'unlink KEY from KEY'. NOT for sprint/epic relationships (mk:jira-agile).
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Send communications through Openapi - SMS with custom sender and OTP (SMS v2), Italian certified e-mail (PEC/Legalmail), bulk certified mail (Massive REM), and physical mail via Poste Italiane (registered letters, telegrams, judicial acts). Use when the user wants to send a message, letter or certified communication.
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Calculates statistical power for high-dimensional genomics experiments (bulk RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, methylation, proteomics) under negative-binomial count models using RNASeqPower, PROPER, and simulation via powsimR, distinguishing per-gene from marginal (transcriptome-wide) power, the role of mean expression and dispersion, and the sequencing-depth-versus-replicate tradeoff. Covers simulation as the honest default for overdispersed counts, FDR-aware average power versus single-test power, observed/post-hoc power as an anti-pattern, and the winner's-curse / Type-S / Type-M consequences of underpowering. Use when planning replicate number for a sequencing experiment, deciding whether to add depth or samples, choosing closed-form versus simulation power, estimating power from pilot dispersions, or justifying replication in a grant. For clinical-trial power see clinical-biostatistics/power-and-sample-size; for the inverse sample-size question see experimental-design/sample-size.
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Estimates the minimum biological replicates (or cells/events) for a target power at a target FDR in genomics experiments using ssizeRNA, PROPER, powsimR for scRNA-seq, and pilot-data dispersion estimation from DESeq2/edgeR. Covers the biological-versus-technical replication distinction (technical replicates do not add degrees of freedom for biological inference), replicate-number-versus-sequencing-depth budgeting, scRNA-seq sample-versus-cell allocation under a pseudobulk model, and the critique that "n=3" is a publication convention rather than a power calculation. Use when budgeting a sequencing experiment, writing the sample-size justification in a grant, estimating replicates from pilot data, allocating a fixed budget between samples and depth, or planning scRNA-seq cohort size. For clinical-trial sample size see clinical-biostatistics/power-and-sample-size; for the power-given-n direction see experimental-design/power-analysis.
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Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity scoring. Covers the motif-pruning-as-directionality principle, regulon specificity scoring, run-to-run stability, and database/species matching. Use when identifying TF regulons, scoring TF activity per cell, finding master regulators of cell identity, or comparing regulon activity across conditions. For enhancer-driven multiomic GRNs see multiomics-grn; for bulk inference and VIPER protein-activity see grn-inference.
日本語の概要は準備中です。原文の説明を表示しています。
Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.
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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
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Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing per-cell QC, choosing between ArchR/Signac/SnapATAC2 ecosystems, building per-cluster consensus peaksets, integrating with paired scRNA-seq, doublet detection (AMULET vs ArchR vs scDblFinder), or running pseudobulk differential accessibility per cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Download large datasets from NCBI efficiently using EPost, history server, batching, rate limiting, and retry logic. Use when bulk-fetching tens of thousands of sequences, pulling all results of a large ESearch, designing reproducible pipelines, comparing E-utilities to NCBI Datasets v2 CLI, or implementing checksum-validated downloads. Encodes WebEnv TTL (~8h), EPost 200-ID limit, retmax caps, parallelization design, and integrity verification.
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Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
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Any live-web task via the Firecrawl CLI — including ordinary web research: searching the web, reading or extracting pages, gathering sources, discovering site URLs, bulk extraction, downloading a site, change alerts, or pages needing clicks/login — web only; local files route to firecrawl-parse. For US legal or regulatory questions use gov; for papers use firecrawl-research-index; for library, API, error, or bug questions use firecrawl-developer-index.
日本語の概要は準備中です。原文の説明を表示しています。
Bulk-extract many pages from one site or section. Use for "crawl", "everything under /docs", or content spanning linked pages.
日本語の概要は準備中です。原文の説明を表示しています。
Send SMS messages with Azure Communication Services SMS Java SDK. Use when implementing SMS notifications, alerts, OTP delivery, bulk messaging, or delivery reports.
日本語の概要は準備中です。原文の説明を表示しています。
Azure Cosmos DB JavaScript/TypeScript SDK (@azure/cosmos) for data plane operations. Use for CRUD operations on documents, queries, bulk operations, and container management.
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When the user needs to generate, iterate, or scale ad creative for paid advertising. Use when they say 'write ad copy,' 'generate headlines,' 'create ad variations,' 'bulk creative,' 'iterate on ads,' 'ad copy validation,' 'RSA headlines,' 'Meta ad copy,' 'LinkedIn ad,' or 'creative testing.' This is pure creative production — distinct from paid-ads (campaign strategy). Use ad-creative when you need the copy, not the campaign plan.
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Build spend analytics and dashboards from Qdrant vector data. Covers bulk scroll extraction, aggregation patterns, vendor grouping, and Chart.js visualization. Use when building analytics features, aggregating procurement data, or creating dashboards.
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Improves Agent Skills via validate → rule-based eval cases → plugin-eval → prompt evals → bounded edits with held-out gates. Use when tuning skill quality, routing, or adopting Chrome/Microsoft T-named quality gates—not for bulk validate-only or SkillOpt automation.
日本語の概要は準備中です。原文の説明を表示しています。