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概要と使いどころ
Time-series database implementation for metrics, IoT, financial data, and observability backends. Use when building dashboards, monitoring systems, IoT platforms, or financial applications. Covers TimescaleDB (PostgreSQL), InfluxDB, ClickHouse, QuestDB, continuous aggregates, downsampling (LTTB), and retention policies.
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Vector database implementation for AI/ML applications, semantic search, and RAG systems. Use when building chatbots, search engines, recommendation systems, or similarity-based retrieval. Covers Qdrant (primary), Pinecone, Milvus, pgvector, Chroma, embedding generation (OpenAI, Voyage, Cohere), chunking strategies, and hybrid search patterns.
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Graph database implementation for relationship-heavy data models. Use when building social networks, recommendation engines, knowledge graphs, or fraud detection. Covers Neo4j (primary), ArangoDB, Amazon Neptune, Cypher query patterns, and graph data modeling.
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Document database implementation for flexible schema applications. Use when building content management, user profiles, catalogs, or event logging. Covers MongoDB (primary), DynamoDB, Firestore, schema design patterns, indexing strategies, and aggregation pipelines.
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Optimize and improve the performance of slow Entity Framework Core (EF Core) queries: make them generate less SQL, make fewer database round-trips, and return results faster. Use whenever an EF Core or DbContext query or data-access path is slow or should be made faster — whether or not EF Core owns the database schema. For EF Core, not Dapper or raw ADO.NET.
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Use when you need framework-agnostic SQL guidance — schema naming, relational table design, query readability, indexes, transactions, database security, migrations, testing, and monitoring — without choosing Spring Boot, Quarkus, or Micronaut. This should trigger for requests such as Review SQL schema or migrations; Improve SQL query performance and readability; Design relational tables and indexes; Review database transaction, security, or monitoring practices. Part of Plinth Toolkit
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Use when you need to add or review Flyway database migrations in a Spring Boot application — Maven dependencies, db/migration scripts, spring.flyway.* configuration, baseline and validation, and alignment with JDBC or Spring Data JDBC. This should trigger for requests such as Add or review Flyway migrations in a Spring Boot project; Configure spring.flyway or db/migration layout; Add versioned Flyway SQL migrations for Spring Boot; Review Spring Boot database migration ordering; Fix repeatable Flyway migrations in a Spring project. Part of Plinth Toolkit
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Use when you need to add or review Flyway database migrations in a Quarkus application — quarkus-flyway extension, db/migration scripts, quarkus.flyway.* configuration, migrate-at-start, and alignment with JDBC or Panache. This should trigger for requests such as Add or review Flyway migrations in a Quarkus project; Configure quarkus-flyway or db/migration layout; Add versioned Flyway SQL migrations for Quarkus; Review Quarkus database migration ordering; Configure Flyway clean migrate or baselines in Quarkus. Part of Plinth Toolkit
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Use when you need to add or review Flyway database migrations in a Micronaut application — micronaut-flyway, db/migration scripts, flyway.datasources.* configuration, and alignment with JDBC or Micronaut Data. This should trigger for requests such as Add or review Flyway migrations in a Micronaut project; Configure micronaut-flyway or db/migration layout; Add versioned Flyway SQL migrations for Micronaut; Review Micronaut database migration ordering; Configure Flyway datasources in a Micronaut project. Part of Plinth Toolkit
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Use when you need to select, review, or implement Java design and integration patterns — including classic Java design patterns, REST API patterns, Kafka and event-driven patterns, database and persistence patterns, and cross-cutting integration patterns. This should trigger for requests such as Apply Java design patterns; Review REST API patterns; Design Kafka event-driven patterns; Improve database persistence patterns; Add resilient integration patterns. Part of Plinth Toolkit
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Managed vector database for production AI applications. Fully managed, auto-scaling, with hybrid search (dense + sparse), metadata filtering, and namespaces. Low latency (<100ms p95). Use for production RAG, recommendation systems, or semantic search at scale. Best for serverless, managed infrastructure.
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CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.
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Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.
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Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task requiring detailed drug and drug target information from DrugBank.
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Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
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Open-source embedding database for AI applications. Store embeddings and metadata, perform vector and full-text search, filter by metadata. Simple 4-function API. Scales from notebooks to production clusters. Use for semantic search, RAG applications, or document retrieval. Best for local development and open-source projects.
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Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
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Use CloudBase document database Web SDK to query, create, update, and delete data. Supports complex queries, pagination, aggregation, and geolocation queries.
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Comprehensive backend development guide for Langfuse's Next.js 14/tRPC/Express/TypeScript monorepo. Use when creating tRPC routers, public API endpoints, BullMQ queue processors, services, or working with tRPC procedures, Next.js API routes, Prisma database access, ClickHouse analytics queries, Redis queues, OpenTelemetry instrumentation, Zod v4 validation, env.mjs configuration, tenant isolation patterns, or async patterns. Covers layered architecture (tRPC procedures → services, queue processors → services), dual database system (PostgreSQL + ClickHouse), projectId filtering for multi-tenant isolation, traceException error handling, observability patterns, and testing strategies (Jest for web, vitest for worker).
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Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
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Postgres best practices maintained by Supabase, for Postgres running anywhere. Load this skill BEFORE writing or changing anything that lives in a Postgres database: creating or altering tables and columns (including choosing column types), schema design, migrations and declarative schema files, RLS policies and the tests that verify them, indexes, triggers, database functions, queues and scheduled jobs (pg_cron, pgmq), vector/semantic search (pgvector), and restoring dumps (pg_restore) or importing data. Also load it when diagnosing slow queries, high CPU, timeouts, EXPLAIN plans, connection exhaustion, locking, bloat, or rows visible to the wrong user or tenant. This is not just a performance guide — schema, migration, security, and SQL authoring tasks need these rules too, even for a one-column change or a single query.
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NCBI Gene via E-utilities: curated records across 1M+ taxa. Official symbols, aliases, RefSeq IDs, summaries, coordinates, GO, interactions. Use for gene ID resolution and cross-species function queries. For sequences use Ensembl; for expression use geo-database.
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JASPAR 2024 TF binding profiles via REST API and pyJASPAR. Retrieve PFMs/PWMs by TF name, JASPAR ID, species, or structural class. Scan DNA for TFBS; browse by taxon (human, mouse) or TF family (bHLH, zinc finger). Use for motif enrichment input, TFBS scanning, and regulatory sequence analysis. For ChIP-seq peak motif discovery use homer-motif-analysis; for regulatory variant scoring use regulomedb-database.
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Query EBI QuickGO REST API for GO terms and protein annotations. Fetch term metadata by ID, search by keyword, walk ancestor/descendant hierarchies, download annotations filtered by taxon, evidence code, aspect. Use for GO resolution, ontology traversal, annotation retrieval before enrichment. Use gseapy-gene-enrichment for enrichment; uniprot-protein-database for proteins.
日本語の概要は準備中です。原文の説明を表示しています。