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Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot; MetaPlotR; deepTools computeMatrix scale-regions), peak-centred heatmaps (ComplexHeatmap; deepTools plotHeatmap), IP-vs-input paired browser tracks (log2 IP/input bigWig via deepTools bamCompare; pyGenomeTracks; Gviz; IGV/UCSC track hubs), DRACH sequence-logo plots (ggseqlogo; MEME), feature-distribution stacked bars, and volcano/MA plots for differential modification. Establishes stop-codon enrichment in the metagene plot as the biological QC anchor for any MeRIP dataset (Dominissini 2012; Meyer 2012). Use when producing the canonical metagene plot with stop-codon enrichment as a QC anchor, building paired IP/input genome-browser tracks at single-locus resolution, plotting peak-centred heatmaps clustered by condition, summarising peak distribution across transcript features, generating DRACH motif logos as sanity checks, rendering volcano plots of differential m6A, or reproducing the stop-codon enrichment plot.

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Query and download from NCBI Gene Expression Omnibus (GEO) and EMBL-EBI's BioStudies/ArrayExpress mirror. Use when finding expression datasets, navigating SuperSeries vs SubSeries, choosing between series-matrix (submitter-normalized) and raw supplementary files, downloading via GEOparse (Python) or GEOquery (R/Bioconductor), linking GEO to SRA for raw reads, or distinguishing GSE/GSM/GPL/GDS record types. Encodes the SuperSeries trap, the series-matrix normalization-trust caveat, GEOmetadb deprecation, ArrayExpress migration to BioStudies, and processed-vs-raw decision matrix.

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Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).

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Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.

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Standardizes molecular structures using the ChEMBL structure pipeline for normalization and parent selection plus RDKit rdMolStandardize for explicit custom steps such as tautomer canonicalization, salt/solvent stripping, charge handling, stereochemistry handling, mixture selection, and isotope normalization. Explicitly compares ChEMBL, canSARchem, RDKit, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

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Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.

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Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee. Guides tool and algorithm selection based on dataset size, sequence divergence, and downstream application. Use when aligning three or more homologous sequences for phylogenetics, conservation analysis, or evolutionary studies.

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Crawl websites (news, blogs, papers, GitHub, product docs, RSS feeds) into a fixed-schema JSONL file, then create a dataset and a searchable application in Viking AI Search. Supports one-time crawl and scheduled recurring crawl with automatic incremental sync.

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Create Viking web projects, start and verify a local preview, or deploy a generated project to Volcengine IGA Pages when explicitly requested. Includes agent-guided feature, eligible application, dataset, scene, and authentication choices. Use only after confirming the installed CLI exposes `vs project`; otherwise stop without taking action.

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Use when a user asks an agent to evaluate or tune text search similarity for an existing Viking AI Search application and dataset.

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Use when the user provides 1-50 concrete bad-case search queries for one Viking Search app and wants local deterministic fixes. This skill only verifies request-level fine-operation interventions against a read-only baseline scene and delivers a console-ready configuration sheet, validated payloads, and a replay script. It must not mutate scenes, apps, dictionaries, datasets, recall core parameters, or online defaults.

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This skill should be used when creating Ultralytics-branded content of any kind, including PDF, PPTX, Canva, or Google Slides presentations, DOCX documents, marketing or newsletter HTML emails, social media post copy or visuals, website or landing page designs, and dataset or model result visuals. Provides official colors, typography, logo rules, naming rules, and tone of voice from ultralytics.com/brand.

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Extract features from 1D signals using signalTimeFeatureExtractor, signalFrequencyFeatureExtractor, and signalTimeFrequencyFeatureExtractor. Use when computing time-domain features (amplitude, energy, shape factors), frequency-domain features (spectral location, power, bandwidth, PSD), or time-frequency features (spectral shape, instantaneous, ridges, wavelet, EMD-derived) on a per-frame basis. Use when the user asks to "extract features", "compute spectral features", "build a feature table for a classifier", "get per-frame statistics", "run feature extraction on this signal", or describes a vibration / biosignal / radar / sensor signal needing features for downstream ML or analysis. Includes optional GPU acceleration via canUseGPU and gpuArray. Does not cover filter design, audio-specific feature extraction (use audioFeatureExtractor in Audio Toolbox instead), batch dataset orchestration, or 2D / image features.

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Import recorded driving sensor data (GPS, camera, lidar, actor tracks, lanes) into scenariobuilder.* objects (GPSData, CameraData, LidarData, ActorTrackData, Trajectory, laneData) and run preprocessing — synchronize, offset correction, crop, normalizeTimestamps, convertTimestamps. Also: compute actor tracks from lidar when no annotations exist, attach camera/lidar mounting + intrinsics, export to MAT/workspace/timetable/script. Use for raw driving dataset files (KITTI, nuScenes, Waymo, Pandaset, ROS/ROS2 bags, .mat, .csv, .mp4) or driving/vehicle/sensor logs that need wrapping. drivingLogAnalyzer (DLA) is OPT-IN ONLY — invoke only on explicit user request ('DLA', 'open in DLA', 'inspect/explore/analyze the recording') or reported sensor problem (sync drift, timestamp mismatch, overlay misalignment). NEVER auto-launch DLA after wrapping (Rule 0). For 'build scenario / export to RoadRunner / drivingScenario / OpenSCENARIO / Unreal / simulate', hand off to matlab-use-scenario-builder.

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Set up infrastructure for fine-tuning LLMs with QLoRA, LoRA, and full fine-tuning using Hugging Face TRL, Axolotl, and distributed training with DeepSpeed or FSDP. Covers dataset prep, training runs, and model export.

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Build automated evaluation suites for AI agents using golden datasets, rubrics, and regression gates. Use when shipping agent features, validating prompt changes, or gating deployments on quality.

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Verify claims, quotations, citations and references against live primary sources, and produce a reproducible audit record instead of an assertion. Use when asked to: check whether a quotation, verse, statistic, date, attribution or citation is accurate; verify references before publishing a report, thesis, article, slide deck or legal filing; confirm a text against an authoritative database; cross-check a claim across independent sources; build a citation register or verification appendix; find out whether two datasets agree; detect a misattributed or fabricated quotation; or audit a document's existing citations. Source-agnostic by design, with working providers for REST/JSON APIs, scraped HTML, bulk corpora, bibliographic catalogues (OpenLibrary), DOI resolution (Crossref) and reference works (Wikipedia) -- including scriptural tiers (Qur'an.com, sunnah.com and an independent hadith corpus) with full diacritic handling for Arabic, Hebrew, Greek and any script with optional marks. Covers content-addressed matching when sources disagree on numbering, graded match verdicts, byte-level integrity checks, published-string verification, and a catalogue of silent failure modes (identifier divergence, mojibake, scraper blocking, false-positive keyword rules, missing glyphs, unreliable PDF text layers).

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Render the multi-agent orchestration DAG for a session — parent→child subagent edges, tree depth, and fan-out — from the Agent Monitor workflow intelligence API. Cross-checks the orchestration dataset against the raw agent records and session detail. Use when visualizing how a session's agent structure was organized.

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Import Claude Code or Codex history and move complete CCAM datasets between machines. Use when rescanning provider history, importing a copied directory, uploading JSONL or archives, exporting a backup, restoring it idempotently, or verifying that tokens, workflows, runs, rules, and pricing survived.

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Trace relationships between semantic models and downstream reports across Fabric workspaces. Automatically invoke when the user asks to "find downstream reports", "show report lineage", "impact analysis", "what depends on this dataset", "cross-workspace lineage", "which reports are connected", "get model dependencies", or mentions model-to-report dependency tracing.

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Automatically invoke this skill whenever the user asks to refresh a semantic model or a dataset. Can also be used to manage, optimize, troubleshoot, or configure a refresh or a refresh schedule.

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This skill should be used whenever the user mentions a "semantic model", "data model", or "dataset", or asks to "build", "model", "design", "optimize", "review", or "audit" one, or to "add a measure", "add a relationship", "create a role" / "set up RLS", "add a calculation group", "set up incremental refresh", "fix a star schema", "reduce model size", "prepare a model for Copilot / AI", or "check model quality". Covers the full lifecycle (design, build, refresh, review) and drives every operation through the `te` CLI first, then TOM (connect-pbid) or a model MCP, then TMDL authoring (the tmdl skill). Not for report visuals (use pbir-cli) or isolated DAX query tuning (use the dax skill).

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When the user wants to add or optimize structured data (Schema.org, JSON-LD). Also use when the user mentions "schema," "structured data," "JSON-LD," "rich results," "rich snippets," "Google rich snippets," "featured snippet schema," "add schema to page," "missing structured data," "schema validation error," "Schema Markup Validator," "Google Rich Results Test," "FAQ schema," "Article schema," "Organization schema," "JobPosting," "HowTo," "Event," "SoftwareApplication," "BreadcrumbList," "WebSite," "Recipe," "Product," or "Dataset." For SERP feature types and zero-click patterns, use serp-features. For AI search visibility strategy (not markup), use generative-engine-optimization. For HowTo step sections (placement, copy, vs FAQ), use howto-section-generator.

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Build or review source-backed descriptive, diagnostic, predictive, and prescriptive analysis for consequential decisions. Use when an agent must profile and safely prepare uploaded data, turn a real dataset or research question into a reproducible study, investigate drivers without overstating causality, validate a model, compare feasible actions under dependent uncertainty and tail risk, trace every parameter to evidence and approval, or produce an answer-first analytical report across health, business, finance, policy, engineering, operations, behavioral science, AI, or planning.

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