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Produce 3D assets with Tripo (tripo3d.ai / Tripo AI by VAST) through its OpenAPI and Studio platform — text-to-3D, image-to-3D, and multiview-to-3D generation; PBR texturing; auto-rigging and preset animation; retopology/low-poly and quad remesh; format conversion (GLB/FBX/OBJ/USDZ/STL/3MF) and engine import (Unity/Unreal/Blender/3D printing). Use when an agent must drive the async task-based Tripo API (create task, poll or webhook, download), choose a model version (v3.0 / v3.1 / P1), write prompts or prepare input images, control mesh/texture parameters, estimate credits and respect rate limits, review generated mesh quality (topology, UVs, poly count, texture fidelity), run iteration and repair workflows, or reason about the rights/licensing of Tripo-generated assets. Trigger on requests to generate, texture, rig, animate, retopologize, convert, or evaluate a 3D model with Tripo, or to integrate the Tripo API into a pipeline. Not for choosing a 3D renderer, editing meshes by hand, or non-Tripo generators.

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Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

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Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

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Access and analyze AlphaFold protein structure predictions. Use when predicted structures are needed for proteins without experimental structures, or for confidence scores (pLDDT).

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Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. Use when orthologs are already curated upstream, when the question is "what is the X ortholog of Y" rather than "how to infer orthology de novo", when batch-mapping gene IDs across species, or when comparing the resources for consensus calls. Encodes confidence-level semantics, 1:1 vs 1:many vs many:many, HomoloGene deprecation, and when to defect to de novo computation.

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Structure retrieval, confidence-aware AlphaFold DB usage, coordinate download, PAE and pLDDT interpretation, and structure-guided biological annotation.

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Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

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Guidance for cell-free protein synthesis (CFPS) optimization. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).

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Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

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Cell-free protein synthesis (CFPS) planning and optimization guidance. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).

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Deep behavioral audit of a Lattice skill — proposes 3 review personas relevant to the skill, runs independent scenario analysis from each persona's perspective, then merges only the high-confidence, practical findings into a severity-ordered gap report with proposed fixes. Structural validation (conventions, cross-references) is skill-validate's job — this skill finds gaps that would realistically surface when someone actually uses the skill: missing scenario handling, ambiguous instructions, silent failure cases, and behavioral inconsistencies. Filters out theoretical edge cases, low-likelihood speculation, and findings owned by other skills. Use after writing or significantly changing any skill, or when the user says 'review this skill', 'deep review', 'does this skill work', 'find gaps in this skill', 'stress test this skill', 'review from different angles', or 'skill review'. Standalone — does not call other skills.

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A React Native developer-platform whose marketing site reads like a quietly-confident infrastructure brand. The base canvas is pure white with a soft sky-blue gradient atmospheric wash behind the hero; near-black ink (`#171717`) carries body and display alike. The single brand voltage is **pure black** (`#000000`) for primary CTAs — minimal and editorial-feeling, paired with a small blue text-link accent (`#0d74ce`) reserved for inline body links. Type pairs Inter at modest weights (display 600, body 400) with JetBrains Mono on every code surface. The brand's strongest visual signature is the **device-mockup hero** — a centered MacBook + iPhone composite showing real Expo dev surfaces — over the gradient sky wash.

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Miro presents itself as the AI-powered visual workspace through a confident, almost playful brand voice — anchored by its signature canary yellow ({colors.brand-yellow}) wordmark over white canvas, broken open by colorful pastel feature tints (rose, teal, coral, orange, mint) that echo the actual sticky-note color palette used on the live whiteboard. Black-pill primary buttons dominate marketing, real Miro-board mockups serve as feature illustrations, and a 4-tier pricing grid leads into a dense comparison table. Roobert PRO carries display headlines; the system supports homepage, pricing, AI Workflows product page, agile vertical, and customer stories surfaces.

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An enterprise-marketing canvas faithful to Carbon Design System: white surfaces, charcoal type, IBM Blue (#0f62fe) as the single confident accent, and a deliberately flat-square aesthetic where corners stay at 0–4px. Type runs IBM Plex Sans at light weight 300 for display sizes (a brand signature) and 400/600 for body and emphasis. Cards live as thin-bordered tiles with no shadow; sections separate via subtle gray rows. The chrome is square, the typography is light, and the only color in the system is one assertive blue — the result reads as old-world enterprise gravitas reframed for the cloud era.

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An enterprise-infrastructure marketing canvas built around a near-black ground (#000000) and a system of per-product accent colors — Terraform purple, Vault yellow, Consul pink, Waypoint cyan, Vagrant blue — that act as identity tokens rather than decorative palette. Display type is hashicorpSans set in 600/700 with tight 1.17–1.21 line-heights; body type runs the same family at 500 weight with relaxed 1.50–1.71 line-heights. Cards live as charcoal surfaces with 1px translucent gray borders; product showcase cards lift into per-product chromatic gradients. The system reads as confident, technical, and intentionally multi-product — every section quietly signals which HashiCorp tool it represents.

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Apply Rob Fitzpatrick's Mom Test discipline to customer interviews during PRD v1.0 Market Adoption. Triggers on requests to interview customers, run discovery calls, validate ideas with users, or when user asks "how do I interview customers?", "Mom Test", "Rob Fitzpatrick", "customer interview", "user research without lies", "talking to humans", "discovery conversation". Outputs CFD-* discovery entries with Mom Test-calibrated confidence.

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Runtime per-test healing with evidence: multi-attribute selector healing, environment-aware diagnosis, flake classification, quarantine management, and confidence-scored auto-repair. Goes beyond simple locator fallbacks to cover action-level healing, data healing, and observable repair workflows. Use when: "flaky test," "test stability," "self-healing locator," "broken locator recovery," "unreliable test," "quarantine flaky test." Not for: bulk regenerating selectors after a planned UI refactor — use selector-drift-recovery (this skill heals ONE test at runtime; that one rewrites many tests offline). Not for: classifying/clustering CI failures into bug reports — use ai-bug-triage. Related: playwright-automation, selector-drift-recovery, ci-cd-integration, qa-metrics, ai-bug-triage.

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Validate release readiness with evidence-based go/no-go decisions. Covers go/no-go checklists, smoke test suite design, staged rollout validation, rollback criteria and procedures, and post-deployment verification. Ensures release confidence comes from data, not feelings. Use when: "release ready," "go/no-go," "smoke test," "release checklist," "rollback plan," "staged rollout," "canary deploy." Not for: safe-release techniques (flags, canary, dark launch) applied during the rollout itself — use testing-in-production; scheduled probes that run continuously after release — use synthetic-monitoring; designing new tests from prod telemetry — use observability-driven-testing. Related: testing-in-production, qa-metrics, ci-cd-integration, ai-system-testing.

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Plans a controlled experiment (A/B test) so its result can be trusted: writes the hypothesis, picks one primary metric and the guardrails, computes sample size and run time, specifies how visitors are assigned and when exposure is logged, and reads out the result with a confidence interval. Use when someone says "set up an A/B test", "split test this page", "how many visitors do I need", "how long should the experiment run", "is this result significant", "can I stop the test early", or wants to test a headline, price, layout or onboarding change against the current version.

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Resilience testing specialist for failure injection, game day planning, and building confidence in system reliabilityUse when "chaos engineering, resilience testing, failure injection, game day, fault tolerance, chaos experiment, disaster recovery, reliability testing, chaos-engineering, resilience, failure-injection, game-day, fault-tolerance, reliability, testing, litmus, chaos-monkey, ml-memory" mentioned.

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Calibrated grilling session for stress-testing a plan, design, idea, or decision. First assesses the user's topic knowledge, confidence, and desired pressure level, then asks one question at a time with recommended answers. Use when user says "grill me", "stress-test this", "challenge my plan", "interview me", or wants a plan probed without being overwhelmed.

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产品设计 / UX 设计 (产品设计 / UX 设计 (Product Design / UX Design) — 数字产品的用户体验设计：从用户研究 → 信息架构 → 交互设计 → 视觉/UI → 可用性测试 → 设计系统的认知操作系统，面向 UX designer / product designer / interaction designer / UX researcher / design systems engineer / design lead，以及想入行、转岗、服务这行(设计外包、设计工具厂商、研究平台)的视角。覆盖: (a) 第一性张力 — **用户中心/研究驱动 (user-centered, 'you are not the user', research before pixels, observe behavior not opinions) ⇄ 商业目标/约束/交付 (business goals, north-star metrics, ship it, designer 服务于产品成功不是个人作品集)**; **设计直觉/品味/craft (taste, aesthetics, 'attractive things work better' — Norman 情感化设计) ⇄ 数据/实验/A-B 测试 (data-driven, metrics, experimentation, 'opinions are not data')**; **用户说的 (stated preference, 访谈里说喜欢) ⇄ 用户做的 (revealed behavior, 行为观察 > 自陈, usability test 看人真实卡在哪)**; **一致性/设计系统/规范 (consistency, design system, Jakob's law 用户带着别处的习惯来, 复用组件) ⇄ 创新/打破模式 (innovation, 该不该破规范)**; **减法/简化 (simplicity, Krug 'Don't Make Me Think', less but better — Dieter Rams) ⇄ 功能丰富/利益相关者塞需求 (feature creep, stakeholder pressure)**; **UX(体验/流程/研究) ⇄ UI(视觉/像素/组件)** 的职责之争, **designer 该不该写代码 (design engineer / 'should designers code')**; (b) 核心工作流 / pipeline (最标准、最易蒸高质量+CLI 化) — Double Diamond (发现 discover → 定义 define → 开发 develop → 交付 deliver) / Design Thinking (共情 empathize → 定义 → 构思 ideate → 原型 prototype → 测试 test) / Design Sprint (Jake Knapp 5 天冲刺); 完整链: 用户研究 (访谈/问卷/可用性测试/卡片分类) → persona / journey map / JTBD → 信息架构 IA + 用户流 user flow → 线框 wireframe (低保真) → 交互/原型 prototype (高保真) → 视觉 UI / 设计系统落地 → 可用性测试 usability testing → handoff 给开发 → 度量迭代 (北极星 / HEART 框架); (c) 工具栈 — 设计/原型 (Figma 绝对主导 / Sketch 衰退 / Adobe XD 已停更 / Framer 高保真+建站 / Penpot 开源 / Principle / ProtoPie 微交互); 协作白板 (FigJam / Miro / Mural); 用户研究 (Maze / UserTesting / Lookback / Dovetail 研究库 / Optimal Workshop 卡片分类树测试 / Hotjar / Microsoft Clarity 热图); 设计系统/交付 (Storybook / 蓝湖(中) / Zeplin / design tokens / Tokens Studio); 度量 (Amplitude / Mixpanel / 北极星指标); AI 新兴 (Figma AI / v0 by Vercel / Galileo AI / Uizard / Cursor 给 design engineer); (d) 知识正典 — Don Norman《The Design of Everyday Things》(affordance/signifier/mapping 圣经)、Steve Krug《Don't Make Me Think》(可用性入门)、Alan Cooper《About Face》《The Inmates Are Running the Asylum》(交互设计/persona 起源)、Jakob Nielsen 10 Usability Heuristics + NN/g 文章库、Jake Knapp《Sprint》、Jeff Gothelf《Lean UX》、Teresa Torres《Continuous Discovery Habits》、Erika Hall《Just Enough Research》、Julie Zhuo《The Making of a Manager》、《Refactoring UI》(Adam Wathan/Steve Schoger)、《Universal Principles of Design》、Laws of UX (Jon Yablonski)、《100 Things Every Designer Needs to Know About People》(Susan Weinschenk)、IDEO/Stanford d.school 设计思维材料; (e) figures/流派 — 认知心理/人因派 (Don Norman 认知科学奠基、Susan Weinschenk 行为心理、Kathryn Whitenton); 可用性工程派 (Jakob Nielsen 启发式/折扣可用性、Steve Krug、Jared Spool UIE); 交互设计/目标导向派 (Alan Cooper goal-directed/persona、Kim Goodwin); 设计思维派 (IDEO Tim Brown、David Kelley d.school); 精益/持续探索派 (Jeff Gothelf Lean UX、Teresa Torres continuous discovery、Marty Cagan《Inspired》产品发现); 设计系统/系统化派 (Brad Frost Atomic Design、Nathan Curtis design tokens、Alla Kholmatova); 视觉/UI craft 派 (Adam Wathan & Steve Schoger Refactoring UI、Dieter Rams 'less but better' 工业设计遗产); 设计领导/职业派 (Julie Zhuo、Aarron Walter 情感化设计、John Maeda); 移动优先 (Luke Wroblewski 'Mobile First'); (f) 行业话术/黑话 — affordance 可供性 / signifier 意符 / mental model 心智模型 / IA 信息架构 / heuristic evaluation 启发式评估 / usability 可用性 / a11y accessibility 无障碍 / WCAG / persona 用户画像 / journey map 用户旅程 / JTBD jobs-to-be-done / north-star metric 北极星 / HEART 框架 / wireframe 线框 / mockup / prototype 原型 / fidelity 保真度 (lo-fi/hi-fi) / design system 设计系统 / design token 设计令牌 / atomic design 原子设计 / component library 组件库 / handoff 交付 / red routes 关键路径 / dark pattern 暗黑模式 / Fitts's law / Hick's law / Jakob's law / Miller 7±2 / progressive disclosure 渐进披露 / above the fold / hamburger menu / skeuomorphism vs flat / micro-interaction / empty state / edge case / happy path / design debt 设计债 / dogfooding / dot voting / affinity mapping 亲和图 / card sorting 卡片分类 / tree testing / A/B test / NPS / SUS (System Usability Scale); (

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Read-only 3-metric governance glance — override rate, small-lane rate, sprint low-confidence ratio — each with a trend arrow vs. the prior 20-commit window.

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Conduct deep OSINT research on individuals. Build full digital footprint, psychoprofile (MBTI/Big Five), career history, social graph with confidence scores. Recursive self-evaluation until completeness threshold is met. Includes internal intelligence (Telegram history, email, vault contacts) before going external. Use when: "osint", "досье", "research person", "find everything about", "пробей", "разведка", "due diligence", "background check", "digital footprint", "найди всё про", "собери информацию", "кто это", "профиль человека". NOT for: company/product research without a named person, competitive analysis, market research, content generation, or general web scraping tasks.

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