「prediction」の検索結果

Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.

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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.

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Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.

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Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or Enformer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.

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Expert causal reasoning and mental model construction for diagnosis and prediction in complex domains

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Query Polymarket: markets, prices, orderbooks, history.

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Turns past decisions into calibrated judgment - scoring old predictions against what happened, assigning credit for delayed results, and separating a bad decision from a good decision that lost. Use during a retrospective, postmortem, quarterly or monthly review, when reviewing decisions taken 30+ days ago, when attributing a result to a cause, or when someone claims to have called something.

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TDD Red Phase - Activate ONE test from the test list and make it fail with explicit predictions

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Chicago CTA L train arrivals, bus predictions, and service alerts.

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BTC15 Autonomous Prediction Market.

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Scans recent X posts for the most debated/hot topic right now in a given category (e.g., crypto, tech, sports.

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Expert-level materials informatics covering materials databases, machine learning for property prediction, high-throughput computation, and data-driven materials discovery.

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Expert-level computational biology covering molecular dynamics simulation, protein structure prediction, systems biology, network analysis, and machine learning in biology.

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Expert-level meteorology covering atmospheric dynamics, thermodynamics, synoptic meteorology, mesoscale systems, numerical weather prediction, and climate dynamics.

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Design leakage-safe machine learning experiments that mirror real deployment and support fair model comparisons. Use when defining prediction timing, feature eligibility, train-validation-test splits, baselines, metrics, or controlled model iterations; not for auditing whether raw labels are trustworthy.

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Isolate the root cause of ML performance drops, inconsistent evaluations, prediction errors, and training-serving mismatches across data, labels, splits, pipelines, models, metrics, and runtime behavior. Use when investigating a reproducible failure or regression, not routine model selection or general performance validation.

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为最终稿创建不可变盲预测日志，并在已有预测时追加新版本。通过 cheat-score-blind 做隔离评分，再由主窗口复核落盘。触发词包括启动预测、start prediction、打分并预测、写预测日志。

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Knowledge base from FAA-HDBK-006D (2020), the FAA's System Reliability, Maintainability, and Availability (RMA) Handbook for National Airspace System (NAS) hardware and software. Use for RMA figures of merit (MTBF, MTBO, MTTR, the availability variants), the bathtub curve and probability distributions, the four-stage RMA lifecycle mapped to the FAA Acquisition Management System (AMS), the six-task RMA technical-management/acquisition process, service-thread criticality and the NAS-RD severity-to-target table, the RMA analysis toolbox (RBD, FMEA/FMECA, FTA, Ishikawa, Monte Carlo, Bayesian, FRACAS, ALT, reliability-growth/recovery tests), software reliability (early prediction + reliability growth), and tailorable example RMA requirements for a Program Requirements Document. Scope limits: it is FAA/NAS-specific guidance (not a requirement, by its own statement), centred on hardware-plus-software availability — it brackets out human/service/facility/communications availability, names but does not reproduce the math derivations or external standards (MIL-STDs, IEEE 1633, RTCA DO-178C/DO-278A, SAE JA1011), is thin on detailed worked numerical examples and on safety-case method, and predates any current revision beyond 006D.

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Review or design FriendlyBet user experience, visual direction, mobile-first flows, premium sports interface, Hebrew/English copy fit, RTL behavior, accessibility, interaction patterns, and product UI polish. Use when a task touches screens, flows, layout, visual hierarchy, onboarding, prediction UX, share UX, or design quality.

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Shape FriendlyBet product decisions, MVP scope, user stories, tournament flows, multi-sport expansion, pool mechanics, social competition loops, and feature prioritization. Use when planning what FriendlyBet should build, cut, sequence, or validate, especially for new sports, prediction formats, pool flows, leaderboards, sharing, or product strategy.

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Model sports rules, event formats, prediction types, scoring implications, lock rules, data requirements, and provider constraints for FriendlyBet. Use when adding or comparing sports such as football, basketball, American football, tennis, tournaments, leagues, playoffs, brackets, weekly picks, or World Cup-specific logic.

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