Use when working with Azure Sql — azure SQL Database DTU/vCore analysis, query performance insights, elastic pool management, geo-replication status, and database health monitoring via Azure CLI.
日本語の概要は準備中です。原文の説明を表示しています。
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概要と使いどころ
Use when working with Azure Sql — azure SQL Database DTU/vCore analysis, query performance insights, elastic pool management, geo-replication status, and database health monitoring via Azure CLI.
日本語の概要は準備中です。原文の説明を表示しています。
AI demos and GPU compute with Gradio Spaces and Hugging Face Spaces ZeroGPU. Use when writing or reviewing code that uses `@spaces.GPU`, configuring `python_version` or `requirements.txt` for a ZeroGPU Space, or handling ZeroGPU-specific code constraints — pickle-based process isolation, `gr.State` semantics across the worker boundary, no `torch.compile` (use AoTI instead), CUDA wheel-only builds (no `nvcc` at build or runtime), large vs xlarge sizing, and dynamic duration callables. Make sure to use this skill whenever the user mentions ZeroGPU, `@spaces.GPU`, or the `spaces` Python package, or hits ZeroGPU-specific code errors like `PicklingError` across the worker boundary, `illegal duration`, or `flash-attn` wheel-build failures — even when the user does not explicitly ask for ZeroGPU coding guidance. Trigger on `import spaces` or `@spaces.GPU` in code.
日本語の概要は準備中です。原文の説明を表示しています。
Implement, review, or improve photo picking, camera capture, and media handling in iOS apps using PhotoKit and AVFoundation. Use when working with PhotosPicker, PHPickerViewController, camera capture sessions (AVCaptureSession), photo library access, image loading and display, video recording, or media permissions. Also use when selecting photos from the library, taking pictures, recording video, processing images, or handling photo/camera privacy permissions in Swift apps.
日本語の概要は準備中です。原文の説明を表示しています。
変更内容を確認し、論理的な単位で複数のコミットに分けて実行します
End-to-end GWAS workflow from VCF to association results. Covers PLINK QC, population structure correction, and association testing for case-control or quantitative traits. Use when running genome-wide association studies.
日本語の概要は準備中です。原文の説明を表示しています。
Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.
日本語の概要は準備中です。原文の説明を表示しています。
Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and pybedtools/pyranges/pandas (Python). Covers the 0-based half-open vs 1-based-closed convention boundary and the start-1/end-unchanged conversion, the silent failures (chrom-name mismatch, CRLF, lexicographic-vs-version sort under -sorted), genome/chrom.sizes generation, sorting contracts, BED12 block invariants, validation, makewindows, cross-assembly liftover (liftOver/CrossMap), and BED<->VCF/BAM/FASTA conversion. Use when reading, creating, validating, sorting, lifting between genome builds, or converting interval files, preparing inputs for bedtools/tabix/bigBed, or debugging an off-by-one or empty-overlap result.
日本語の概要は準備中です。原文の説明を表示しています。
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying VCEP-specific CSpec rules, computing Whiffin BS1, or assigning cancer Tier I-IV per Li 2017.
日本語の概要は準備中です。原文の説明を表示しています。
Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.
日本語の概要は準備中です。原文の説明を表示しています。
Extracts and assigns COSMIC v3.4 mutational signatures (84 SBS / 11 DBS / 18 ID / 24 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.
日本語の概要は準備中です。原文の説明を表示しています。
集群数据管理 Skill —— 涵盖数据使用规范、压缩优化、数据共享(ACL)、文件扫描与清理、文件完整性校验、genozip 基因组压缩等全流程。Use when the user asks about: managing data on the HPC cluster, compressing genomic files (fq/bam/vcf), sharing data between users/groups, scanning for large files or cleaning up disk space, checking file integrity (md5/gzip/bam), using genozip, checking disk quota, or any data lifecycle management task on the NCPGR HPC cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Provides expert knowledge of Spring Boot conventions, Kotlin idioms, and MVC patterns for backend API development.
日本語の概要は準備中です。原文の説明を表示しています。
Use when writing tests of any kind — unit, slice, or integration. Covers test structure, naming conventions, Mockito patterns, @WebMvcTest, @DataJpaTest, and Testcontainers setup.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill when you need to derive, from web-sourced evidence, typical values for a named plant's annual GPP, LAI, specific LAI or specific leaf area, Rubisco Vcmax at 25oC, Jmax at 25oC, root-to-shoot ratio, rooting depth, leaf protein nitrogen, and leaf chlorophyll nitrogen.
日本語の概要は準備中です。原文の説明を表示しています。
Extract typical annual GPP, annual evapotranspiration, mid-season LAI, mid-season root biomass, mid-season shoot biomass, median canopy height, maximum primary-root depth, Vcmax at 25oC, and Jmax at 25oC from EcoSIM h0 NetCDF output files. Use when asked to derive these EcoSIM output targets from a selected .ecosim.h0.*.nc file for model-output processing, trait checks, or benchmark summaries.
日本語の概要は準備中です。原文の説明を表示しています。
投行 strategic-alternatives pitch book — trading comps / precedent transactions / valuation football field / DCF sensitivity / 战略选项矩阵 / 流程建议。改写 assets/template.html 保留 IB-specific chrome / disclosure bands / source labels。用于 Board / sell-side 讨论材料。**不是** VC 融资 deck。工作流改自 Anthropic financial-services Pitch Agent (Apache-2.0)。
日本語の概要は準備中です。原文の説明を表示しています。
Diagnóstico e operação de Kubernetes — pods, deployments, ingress, HPA, PVC, StorageClass, NetworkPolicy, Secrets, Helm, ArgoCD, cert-manager. Use quando o usuário disser "kubernetes", "k8s", "pod", "deployment", "ingress", "CrashLoopBackOff", "não sobe", "escalar", "helm", "argocd". Leitura livre; apply, scale, delete passam pelo portão.
日本語の概要は準備中です。原文の説明を表示しています。
Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.
日本語の概要は準備中です。原文の説明を表示しています。
Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and pybedtools/pyranges/pandas (Python). Covers the 0-based half-open vs 1-based-closed convention boundary and the start-1/end-unchanged conversion, the silent failures (chrom-name mismatch, CRLF, lexicographic-vs-version sort under -sorted), genome/chrom.sizes generation, sorting contracts, BED12 block invariants, validation, makewindows, cross-assembly liftover (liftOver/CrossMap), and BED<->VCF/BAM/FASTA conversion. Use when reading, creating, validating, sorting, lifting between genome builds, or converting interval files, preparing inputs for bedtools/tabix/bigBed, or debugging an off-by-one or empty-overlap result.
日本語の概要は準備中です。原文の説明を表示しています。
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying VCEP-specific CSpec rules, computing Whiffin BS1, or assigning cancer Tier I-IV per Li 2017.
日本語の概要は準備中です。原文の説明を表示しています。
Extracts and assigns COSMIC v3.4 mutational signatures (84 SBS / 11 DBS / 18 ID / 24 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.
日本語の概要は準備中です。原文の説明を表示しています。
Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.
日本語の概要は準備中です。原文の説明を表示しています。
集群数据管理 Skill —— 涵盖数据使用规范、压缩优化、数据共享(ACL)、文件扫描与清理、文件完整性校验、genozip 基因组压缩等全流程。Use when the user asks about: managing data on the HPC cluster, compressing genomic files (fq/bam/vcf), sharing data between users/groups, scanning for large files or cleaning up disk space, checking file integrity (md5/gzip/bam), using genozip, checking disk quota, or any data lifecycle management task on the NCPGR HPC cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Action-Domain-Responder pattern knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for ADR (web-specific MVC alternative) audits.
日本語の概要は準備中です。原文の説明を表示しています。