3万 件 ・ 関連度順
概要と使いどころ
Provides integration patterns for LangChain4j with Spring Boot. Configures AI model beans, sets up chat memory with Spring context, integrates RAG pipelines with Spring Data, and handles auto-configuration, dependency injection, and Spring ecosystem integration. Use when embedding LangChain4j into Spring Boot applications, building Java LLM applications with @Bean configuration, or setting up Spring AI patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Fine-tune LLMs using reinforcement learning with TRL - SFT for instruction tuning, DPO for preference alignment, PPO/GRPO for reward optimization, and reward model training. Use when need RLHF, align model with preferences, or train from human feedback. Works with HuggingFace Transformers.
日本語の概要は準備中です。原文の説明を表示しています。
Use Neon serverless Postgres with branching, connection pooling, and instant scalability for modern applications with Prisma or Drizzle ORM integration. Use when setting up serverless Postgres databases, implementing database branching for preview environments, configuring connection pooling, optimizing for serverless cold starts, using Prisma with Neon, implementing database migrations, scaling databases automatically, or building applications on Vercel/Netlify with Postgres.
日本語の概要は準備中です。原文の説明を表示しています。
Build beautiful, accessible UI components using shadcn/ui library with Radix UI primitives and Tailwind CSS styling that you own and can customize. Use when creating accessible component libraries, implementing common UI patterns (dialogs, dropdowns, tooltips), building forms with validation, creating data tables, implementing command palettes, using Radix UI primitives, customizing components with Tailwind, or building design systems with full ownership of code.
日本語の概要は準備中です。原文の説明を表示しています。
Apply one logical code change with mandatory impact mapping, git snapshot, verification, and automatic revert on failure. Load when the user asks for a safe edit, verified change, one change at a time with rollback, or codespine-style edit loop. Also triggers on "safe change", "edit with verification", "don't break the build", "revert if tests fail", or any non-trivial code edit where blast radius matters. Always runs dependency-mapping first. Pairs with incremental-implementation for multi-slice work; this skill is one atomic verify cycle per invocation.
日本語の概要は準備中です。原文の説明を表示しています。
Parses, queries, converts, and extracts from GTF and GFF3 gene-model annotation files - walking the gene/transcript/exon/CDS hierarchy with gffutils (queryable SQLite DB), converting formats and extracting transcript/CDS/protein FASTA with gffread, slurping to dataframes with gtfparse/pyranges, and sanitizing malformed files with AGAT. Covers the 1-based-inclusive vs 0-based BED coordinate conversion (start-1 only), deriving implicit features (introns/UTRs/TSS), phase-not-frame, the stop-codon-in-or-out-of-CDS convention, and the chr1-vs-1 seqid and gene-ID-version mismatches that silently produce all-zero count matrices and dropped joins. Use when extracting features or sequences from an annotation, converting GTF<->GFF3 or GTF->BED, traversing the gene tree, or diagnosing a coordinate/provenance mismatch upstream of counting or DE.
日本語の概要は準備中です。原文の説明を表示しています。
Assigns pathogen lineages (SARS-CoV-2 Pangolin via UShER mode; Nextclade clade + QC; pango-designation alias_key.json resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage fitness modelling (Wenseleers / Bedford-Figgins multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data version pinning (mandatory for reproducibility), Nextclade dataset versioning (lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme version churn (V3 / V4 / V4.1 / V5.3.2 / Midnight 1200) with documented dropout regions, recombinant X-prefix Pango designation lag, GISAID vs INSDC dual-deposition tensions, and the Karthikeyan 2022 wastewater early-detection signal with explicit reproducibility caveats. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater pooled samples into lineage frequencies with Freyja, tracking lineage frequencies and growth advantages over time, pinning pangolin-data / Nextclade dataset versions for reproducibility, handling ARTIC primer dropouts (V4.1 amplicons 64 / 76 / 88-90), or running variant surveillance for SARS-CoV-2 / influenza / Mpox / RSV / H5N1 / measles.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.
日本語の概要は準備中です。原文の説明を表示しています。
Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Li & Hart 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving 2-3x sensitivity over MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).
日本語の概要は準備中です。原文の説明を表示しています。
Enables Claude Code to collaborate with OpenAI Codex CLI on Windows. Use this skill when the user wants to get a second opinion from Codex, compare approaches between Claude and Codex, or leverage both AI assistants for collaborative problem-solving. This skill supports both non-interactive mode (automatic response retrieval) and interactive mode (visual pane splitting with tmux).
日本語の概要は準備中です。原文の説明を表示しています。
This skill should be used when the user wants to "synthesize two competing solutions without averaging", "resolve a design/value disagreement by lifting to a higher frame", "止揚 / アウフヘーベン", "矛盾を止揚", "独立案を統合", "平均化せず統合", "contradiction lift", "sublate competing designs", or has two good-but-divergent answers to the same question and wants a higher-order resolution (a selection mechanism) or an honest aporia — not a compromise. NOTE: Use this when two independent solutions diverge and you want to PRESERVE both truth-moments while lifting to a higher frame. Use devils-advocate to stress-test ONE proposal with an assigned opponent, strong-inference to find an unknown cause, and dialectic-loop to validate a claim against a real corpus.
Work with state-of-the-art machine learning models for NLP, computer vision, audio, and multimodal tasks using HuggingFace Transformers. This skill should be used when fine-tuning pre-trained models, performing inference with pipelines, generating text, training sequence models, or working with BERT, GPT, T5, ViT, and other transformer architectures. Covers model loading, tokenization, training with Trainer API, text generation strategies, and task-specific patterns for classification, NER, QA, summarization, translation, and image tasks. (plugin:scientific-packages@claude-scientific-skills)
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive red team operations methodology covering full engagement lifecycle from planning through reporting. Addresses engagement scoping and rules of engagement negotiation, multi-tier C2 infrastructure design with redirectors and domain fronting, malleable traffic profiles and beacon tradecraft, OPSEC discipline including attribution avoidance and indicator management, EDR and AMSI evasion techniques using direct syscalls and unhooking, data collection with chain-of-custody controls, and structured reporting with purple team debrief workflows. Covers assumed-breach, external-to-internal, insider threat, and hybrid physical-cyber engagement scenarios with MITRE ATT&CK mapping throughout. Targets operators planning or executing adversary simulation engagements against mature defenders.
日本語の概要は準備中です。原文の説明を表示しています。
Requires OFOX_API_KEY — create one at https://app.ofox.ai. Turn a novel/script excerpt into an anime-style storyboard shot using the Ofox image and video APIs. Runs a short creative brief first (how many shots, the aspect ratio before any image exists, which animation look; "Let the AI decide" is offered on the taste questions, never on a must-ask one, and never as the default), generates the character with ofox-image-core — one opening frame for a single shot, a design sheet to confirm plus one opening frame per shot for a sequence — then feeds each frame to ofox-video-core as `--frame-first-image`, so every shot starts on an image of that character rather than on a text description alone. Use when a user asks to turn a story excerpt into an anime video, e.g. "turn this novel excerpt into an anime video", "make an anime-style storyboard clip of this scene", "generate a manga-drama shot with this character", or "turn this chapter into an anime short with the same character in every shot". Do not use for realistic-human dialogue scenes with no anime styling (see seedance-short-drama), silent product/brand shots (see seedance-ad-creative), or plain catalog footage (see seedance-product-video).
日本語の概要は準備中です。原文の説明を表示しています。
Telegramのテスト環境で実ユーザーとしてOpenClawを操作し、応答や編集・削除・リアクションなどを記録して、利用者に見える動作を検証するスキル。
OpenClawのチャット接続を設定し、実際のテスト送信で届くか確認します。トークンを露出させず、既存のアクセス制限を守りながら接続の問題も調べます。
OpenClawのブラウザ操作で、ログイン状態やタブを確認しながら複数手順の作業を進めます。古くなった操作対象の参照やタイムアウトへの対処も扱います。
AIエージェントと外部ツールをつなぐMCPサーバーを、コマンドで一覧表示・設定・認証し、ツールの呼び出しや入出力の仕様確認まで行うスキル。
文章をローカル環境で読み上げ音声に変換し、WAVファイルに保存します。sherpa-onnxの音声モデルを使い、クラウドに接続せずに音声を生成します。
OpenClawにモデル提供サービスを追加し、実際の応答まで確認するスキル。認証情報は環境変数やファイルへの参照で扱い、設定の検証と結果報告も進めます。
コードレビューの指摘を実際のコードや対応環境と照らし合わせ、妥当性を確認します。不明点の整理、根拠を示した返答、修正ごとのテストまで進めるスキルです。
作成済みの実装計画を、同じセッションでタスクごとに実行します。テストの失敗と成功、進捗や判断を記録し、最後にブランチ全体をレビューするスキルです。
仕事や暮らしの繰り返し作業を質問で掘り下げ、開始条件や人の確認、判断用の要約を整理して、実装担当が追加質問なしで作れるワークフロー仕様にするスキル。