「actors」の検索結果

MITRE ATT&CK is a globally-accessible knowledge base of adversary tactics, techniques, and procedures (TTPs) based on real-world observations. This skill covers systematically mapping threat actor beh

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Use the Malpedia platform and API to research malware family relationships, track variant evolution, link families to threat actors, and integrate YARA rules for detection across malware lineages.

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Diagnose why a product metric changed (dropped, spiked, or plateaued) by orchestrating breakdowns, actors, paths, lifecycle, retention, and annotations queries. Use when the user reports an anomaly, asks "why did X change?", or needs root-cause analysis for a trend, funnel, retention, stickiness, or lifecycle metric.

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Solve a hard problem by trying multiple approaches in parallel using isolated git worktrees. Each attempt runs in its own branch, and the best solution is selected. Use for complex refactors, tricky bugs, or architectural decisions where multiple strategies could work.

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Drug safety and adverse event analysis — FAERS spontaneous-report mining, FDA black-box warnings, signal detection (PRR, ROR, IC), risk factors by demographic/comorbidity, and label change tracking. Use for post-market safety surveillance, AE signal investigation, drug-AE association strength scoring, and pharmacovigilance reports.

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Draws debug overlays in a running CARLA world via world.debug — points, lines, arrows, bounding boxes, and text strings, each with a colour and lifetime. Use when the user asks to "draw/mark/highlight a point or box in the world", "visualise a path/waypoints", "label a location", or "show something on the map for debugging". Shapes are an overlay, not actors.

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Gets actor and level 3D bounding boxes and projects them into a camera image as 2D boxes — the dataset-annotation workflow. Lists box geometry, draws 3D boxes in the world via debug, or captures one camera frame and writes an annotated PNG plus a JSON of 2D boxes for matching actors. Use when the user asks to "get bounding boxes", "draw boxes around the cars", "project boxes onto the camera", or "generate a detection dataset / annotations".

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Keep GPT-5.6 and other coding-agent work proportional to the request by locking scope, choosing the smallest sufficient implementation, matching verification to risk, and stopping when success is proven. Use for implementations, bug fixes, refactors, reviews, or maintenance where scope creep, speculative abstractions, unrelated cleanup, repeated test runs, unnecessary dependencies, or polishing beyond the request are risks.

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Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and coverage-biased, so generic Hi-C loop callers (cooltools dots, Juicer HiCCUPS) use the wrong null. Covers FitHiChIP (config-driven coverage+distance-decay spline regression, peak-to-peak vs peak-to-all foreground, loose vs stringent background, coverage vs ICE bias), MAPS (positive Poisson regression on bias factors for PLAC-seq/HiChIP), hichipper (restriction-site-distance bias model + library QC), CHiCAGO (Delaporte two-component Brownian+technical background for asymmetric bait x other-end Capture Hi-C), the with/without separate-ChIP anchor decision, and differential loops via diffloop. Use when calling loops from HiChIP/PLAC-seq/Capture Hi-C, choosing FitHiChIP/MAPS/CHiCAGO, picking peak-to-all vs peak-to-peak, setting the loop FDR, supplying ChIP peaks as anchors, QCing a HiChIP library, or comparing loops between conditions.

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Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.

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Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.

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Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, and applies the Patel et al 2024 *Nat Biotechnol* review's failure-mode framework to validate that normalization is correctly applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.

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Scrape leads from multiple platforms using Apify Actors.

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AI-driven data extraction from 55+ Actors across all major platforms. This skill automatically selects the best Actor for your task.

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Scrape reviews, ratings, and brand mentions from multiple platforms using Apify Actors.

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Actorization converts existing software into reusable serverless applications compatible with the Apify platform. Actors are programs packaged as Docker images that accept well-defined JSON input, perform an action, and optionally produce structured JSON output.

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Run multiple Reforge-guided section-refactor lanes in parallel, each in its own worktree/branch off origin/main, with a score-blind adversarial review panel gating every commit, one draft PR per section. Use when the user wants to reduce Reforge surface/internal score across several sections at once via architecturally-correct deletions (dead surface, entity-leak removal, cross-section read-splits) — not by relocation, parameter bags, or accessibility-dodging. Wraps the per-lane process in .codex/skills/humans-refactor. Triggers: 'refactor swarm', 'parallel section refactors', 'run reforge refactor on Users/Tickets/...', 'burn down surface score across sections'. Has an intensity dial (light|standard|deep) and a workflow|solo execution mode to trade token burn against autonomy per unit of output.

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iOS and Swift/SwiftUI development guidance, including App Clips, haptics, UI patterns, Liquid Glass styling, performance audits, view refactors, Swift concurrency, and iOS debugging. Use when building or reviewing iOS apps, SwiftUI views, or troubleshooting iOS issues.

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iOS and Swift/SwiftUI development guidance, including UI patterns, Liquid Glass styling, performance audits, view refactors, Swift concurrency, and iOS debugging. Use when building or reviewing iOS apps, SwiftUI views, or troubleshooting iOS issues.

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Plan ATM framework refactors by preserving atom/map semantics before splitting large governance modules.

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Decompose an unknown quantity into 3-5 estimable factors and produce a defensible order-of-magnitude answer without needing precise data. Load when the user needs to size something without data — market size, resource requirements, effort estimates, user numbers, costs — or when a decision is blocked by "we don't know the numbers". Also triggers on "ballpark this", "rough estimate", "how big is this market", "how long would this take", "how many users", or when deep-thinking diagnoses a sizing/estimation frame. The goal is not precision — it is a defensible answer that enables a decision to be made. Based on Enrico Fermi's estimation method.

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Automate web scraping and data extraction with Apify -- run Actors, manage datasets, create reusable tasks, and retrieve crawl results through the Composio Apify integration.

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Run large codebase migrations and multi-file refactors. Uses the Composio CLI to coordinate issue tracking, batched PRs, and CI verification while the agent executes the transforms locally across hundreds of files.

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Scrape reviews, ratings, and brand mentions from multiple platforms using Apify Actors.

日本語の概要は準備中です。原文の説明を表示しています。