92 件 ・ 関連度順
概要と使いどころ
Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation. Use when manually annotating cell types for training classifiers or validating automated phenotyping results.
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Organization-grade cloud and supply-chain attack-surface discovery: S3/GCS/Azure Blob bucket discovery via observed-name mining (CNAME/cert-SAN/Wayback) and bounded two-class permutation (6 prefixes x 15 suffixes on trusted tokens, bounded target-bound expansion on subdomain stems), existence (HEAD/GET) vs public-listing confirmation, object-key triage into 9 value tiers (database dumps, credentials, IaC state, kubeconfig, VCS dirs, config, archives, PII, logs), dangling-CNAME bucket-takeover detection, and the ownership-gated severity model that stops an unattributable public bucket from becoming a false CRITICAL; the fully offline AWS-account-ID recovery from a leaked AKIA/ASIA/AROA access key (base32 decode, runnable stdlib Python, canonical test vector, AWS-documentation-example-ID screening); dependency-confusion confirmation for npm/PyPI (internal-signal classifier -- private-registry binding vs org-namespace match -- paired with a read-only public-registry 404 check and the npm scope-claimability nuance the public search API misses); and passive cloud-native/container/Kubernetes/CI control-plane fingerprinting (Lambda URLs, API Gateway, Cloud Run, App Service, kubelet/etcd/K8s API/dashboard, Jenkins/GitLab/Argo CD) as an org-attribution and exposure surface. Passive/discovery only -- no exploitation, no credential submission, no active control-plane confirmation (a stage-6 validate_cloud active tier is described but out of scope). Use when enumerating a target's cloud storage footprint, recovering an AWS account ID from a leaked key, confirming a supply-chain dependency-confusion vector, or fingerprinting cloud-native/K8s/CI infrastructure for an authorized external recon engagement.
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LLM-based zero-shot and few-shot classification for flexible intent detection
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Hugging Face transformer model fine-tuning and inference for intent classification
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Write a PRD for an AI-powered feature, covering the things normal PRDs miss. Use when asked to spec an AI/LLM feature, write a PRD for a feature that uses a model, or plan an AI capability (assistant, summarizer, generator, classifier). Produces an AI feature PRD — problem & UX of uncertainty, model approach, eval criteria, guardrails, fallback behaviour, the data flywheel, and cost/latency budget.
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Assign cell types from marker expression in IMC/MIBI data using clustering (PhenoGraph/FlowSOM/Leiden/Pixie), marker-based probabilistic classifiers (Astir), or image-context CNNs (CellSighter), covering the double-positive segmentation artifact, lineage-vs-state markers, the two spillover types, and why a "cell type" in imaging is conditioned on a segmentation guess. Use when phenotyping segmented IMC cells, choosing clustering vs classification, diagnosing implausible double-positive populations, separating lineage from functional markers, or transferring labels across a cohort.
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Extracts cfDNA fragmentomics features (DELFI genome-wide short/long ratios, WPS nucleosome positioning, Griffin GC-corrected accessibility profiles, end-motifs/MDS, OCF) for cancer detection and tissue-of-origin from plasma WGS. Centers on the nuclease-footprint reframe (every feature re-reads one nucleosome object), the mandatory GC correction, and the cross-protocol non-comparability that breaks naive classifiers. Runs FinaleToolkit (real CLI/Python, MIT) and the Griffin Snakemake pipeline; DELFI is a method, not a package. Use when deriving fragment-based signal from cfDNA, choosing a feature family for detection vs subtyping, or diagnosing why a fragmentomic model failed validation.
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Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
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Processes eDNA metabarcoding from raw paired-end reads to species tables, navigating ASV (DADA2, UNOISE3) vs OTU (swarm v2) decision (Callahan 2017 vs Schloss multi-copy-16S critique), marker/primer choice (Leray COI, MiFish 12S, 515F/806R 16S, ITS2) with primer-specific bias, OBITools3 v3 command-name break (obi stats plural; .tar.gz taxonomy), tag-jumping with dual-indexing (Schnell 2015; NovaSeq 10x MiSeq), decontam as screening-not-classifier (Davis 2018), read-counts-not-abundance critique (Lamb 2019), site-occupancy modeling (Ficetola 2015), Naive-Bayes calibration limits (Bokulich 2018), and eDNA decay (Strickler 2015). Use when going from raw eDNA FASTQ to species tables, picking marker + denoising pipeline, deciding whether read counts represent abundance, applying occupancy modeling, configuring OBITools3 v3, or interpreting decontam output. Not for clinical 16S microbiome (see microbiome/amplicon-processing).
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Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.
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Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF calibration (BF >6 ≈ 90% posterior per Hart 2017; ~5% FDR by BAGEL convention). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.
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Extract features from 1D signals using signalTimeFeatureExtractor, signalFrequencyFeatureExtractor, and signalTimeFrequencyFeatureExtractor. Use when computing time-domain features (amplitude, energy, shape factors), frequency-domain features (spectral location, power, bandwidth, PSD), or time-frequency features (spectral shape, instantaneous, ridges, wavelet, EMD-derived) on a per-frame basis. Use when the user asks to "extract features", "compute spectral features", "build a feature table for a classifier", "get per-frame statistics", "run feature extraction on this signal", or describes a vibration / biosignal / radar / sensor signal needing features for downstream ML or analysis. Includes optional GPU acceleration via canUseGPU and gpuArray. Does not cover filter design, audio-specific feature extraction (use audioFeatureExtractor in Audio Toolbox instead), batch dataset orchestration, or 2D / image features.
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Find the decisions in a pipeline that do not need the expensive model and propose the gate for each: a rule, a classic classifier, or a small model, with fail-closed routing. Use when the user asks to cut model costs or latency, says the big model handles everything, or wants a triage / routing / filter layer in front of an agent. Analysis plus an optional baseline scaffold. Do NOT use for auditing context layout (context-audit) or for building eval suites (evals-bootstrap).
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Classify each parsed mathematical-modeling subquestion by required output and structure, surface ambiguous framing trade-offs for human choice, and record primary/secondary task types without selecting algorithms.
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Assesses which of the Art. 50(1)-(5) transparency obligations of the EU AI Act apply to a given AI system's provider or deployer, grounded in the final Code of Practice on Transparency of AI-Generated Content (June 2026) and the Commission's draft Art. 50 Guidelines. Covers AI-chatbot disclosure, deepfake and synthetic-content marking/watermarking, emotion-recognition and biometric-categorisation notices, the machine-readable marking duty, the obviousness exceptions, and the implementation timeline. Outputs a formal mini-report plus a per-obligation compliance checklist with gap flags. For breadth-first tier triage use the EU AI Act System Classifier; for raw Art. 50 text and Q&A use the EU AI Act Knowledge Base; for the full role x tier matrix use the EU AI Act Obligations Mapper.
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Depth assessment of whether an AI system is high-risk under Art. 6 of the EU AI Act, grounded in the Commission's draft Art. 6(5) classification guidelines (general principles + Annex I + Annex III). Covers the Annex I product-safety route, all eight Annex III areas with worked examples, the Art. 6(3) exception and its profiling re-exception, and the Art. 25 quasi-provider trap. Outputs a structured decision block, a practitioner memo, and a JSON interchange artefact.
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A post hoc cell type classification tool to fine-tune cell type annotations generated by any cell type classification procedure with semi-supervised learning algorithm AdaSampling technique. The current version of scReClassify supports Support Vector Machine and Random Forest as a base classifier.
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ML trading signal classifiers using XGBoost and LightGBM with walk-forward validation, SHAP feature importance, and threshold optimization
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Classify construction data by type (structured, unstructured, semi-structured). Analyze data sources and recommend appropriate storage/processing methods
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Use Diffusion Planner for nuPlan autonomous-driving trajectory generation: prepare model-ready data, train or resume the diffusion model, configure closed-loop planning, and add differentiable collision or classifier guidance.
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Use the DataSciencePython tutorial/example collection through modern self-contained helpers for Python data-science resources, statsmodels logistic regression, scikit-learn Kaggle-style tabular classifiers, and Twitter JSONL extraction.
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Use CellTypist for single-cell RNA-seq cell type annotation, model management, custom classifier training, CLI usage, and result visualization workflows.
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Think and work like an expert Computational Social Scientist. Use when a task calls for Computational Social Scientist judgment. Reasons from social mechanisms, measurement validity, and sampling frames through DAGs, fixed-effects and IV/DiD/RDD designs, ERGM/SAOM network models, and human-audited text classifiers while treating unobserved homophily, network interference and SUTVA violations, platform-driven selection, bot contamination, and digital-skew unrepresentativeness as first-class failure modes.
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Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.
日本語の概要は準備中です。原文の説明を表示しています。