「correction」の検索結果

Bead-based signal normalization and cross-batch harmonization for CyTOF and high-parameter cytometry - EQ four-element bead normalization of instrument sensitivity drift (CATALYST normCytof, premessa), and reference-anchor cross-batch normalization (CytoNorm, per-cluster quantile splines). Covers the distinction between within-run drift correction and between-batch correction, the mandatory anchor/reference sample, why normalization is per-cluster with many quantiles, and the over-correction risk. Use when correcting CyTOF signal drift, harmonizing multi-batch or multi-site studies, or deciding whether to normalize data versus model batch in the design.

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Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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When the user corrects a factual error, root-cause it immediately. Don't just note the correction — trace the error to its source, fix the source, and prevent recurrence. Every factual error is either a data error (bad brain page, bad memory file, bad rendered SOUL/USER identity, bad facts row) or a hallucination (LLM confabulated from partial signals).

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Deep learning for single-cell analysis using scvi-tools. This skill should be used when users need (1) data integration and batch correction with scVI/scANVI, (2) ATAC-seq analysis with PeakVI, (3) CITE-seq multi-modal analysis with totalVI, (4) multiome RNA+ATAC analysis with MultiVI, (5) spatial transcriptomics deconvolution with DestVI, (6) label transfer and reference mapping with scANVI/scArches, (7) RNA velocity with veloVI, or (8) any deep learning-based single-cell method. Triggers include mentions of scVI, scANVI, totalVI, PeakVI, MultiVI, DestVI, veloVI, sysVI, scArches, variational autoencoder, VAE, batch correction, data integration, multi-modal, CITE-seq, multiome, reference mapping, latent space.

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Walk through a Data Subject Access Request (or deletion, portability, correction request) and draft the response — verify identity, locate data system-by-system, assess exemptions, draft the acknowledgment and substantive response letters. Use when a DSAR comes in, the user pastes an access/deletion/portability/correction request, or says "DSAR came in", "access request", "right to be forgotten", or "someone wants their data".

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Batch effect correction for CRISPR screens. Covers normalization across batches, technical replicate handling, and batch-aware analysis. Use when combining screens from multiple batches or correcting systematic technical variation.

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Capture a correction or lesson as a persistent learning rule with category, mistake, and correction. Stores, categorises, and retrieves rules for future sessions. Use after mistakes or when the user says "remember this", "don't forget", "note this", or "learn from this".

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SkillOpt-flavored offline training loop for any SKILL.md. Treats accumulated learn-rule corrections as training trajectories, proposes bounded patches via an optimizer LLM, gates each candidate against a held-out validation set built from the user's own past corrections, and ships only candidates that demonstrably improve the score. Inspired by Microsoft SkillOpt's ReflACT pipeline (rollout → reflect → aggregate → select → update → evaluate) adapted to pro-workflow's SQLite store. Use when a skill has accumulated 8+ learn-rule rows and the user wants the skill itself to get better, not just longer.

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Self-learning system that captures corrections during sessions and reminds users to run /reflect to update CLAUDE.md. Use when discussing learnings, corrections, or when the user mentions remembering something for future sessions.

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Deep learning for single-cell analysis using scvi-tools. This skill should be used when users need (1) data integration and batch correction with scVI/scANVI, (2) ATAC-seq analysis with PeakVI, (3) CITE-seq multi-modal analysis with totalVI, (4) multiome RNA+ATAC analysis with MultiVI, (5) spatial transcriptomics deconvolution with DestVI, (6) label transfer and reference mapping with scANVI/scArches, (7) RNA velocity with veloVI, or (8) any deep learning-based single-cell method. Triggers include mentions of scVI, scANVI, totalVI, PeakVI, MultiVI, DestVI, veloVI, sysVI, scArches, variational autoencoder, VAE, batch correction, data integration, multi-modal, CITE-seq, multiome, reference mapping, latent space.

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.omd/preferences.md의 status:pending 항목을 Core v2 System Graph에 합쳐 DESIGN.md를 재생성하고 status를 applied로 플립. '프리퍼런스 정리해줘', 'fold preferences', 'apply all corrections', 「好みをDESIGN.mdに反映」, 「套用偏好」류의 요청에 트리거. 단발성 교정 기록은 omd:remember.

Analyzes conversation transcripts to extract user corrections, patterns, and preferences, then proposes skill improvements. Use this skill when users provide corrections, express preferences about code style, or when patterns emerge from successful approaches. Can be triggered manually with /reflect or automatically at session end when enabled.

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Harmony batch correction for scRNA-seq and other omics. Removes batch effects from PCA embeddings while preserving biology. Run after PCA, before UMAP. Scales to millions of cells. Python (harmonypy, scanpy) and R (Seurat).

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Generates a structured Bug Fix Brief (BFB) to document issue corrections. Includes root cause analysis, repro steps, fix options, and fix checklist. Use when user asks to create a BFB, document a bug fix, or generate a bug correction document.

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Think and work like an expert Metabolomics Scientist. Use when a task calls for Metabolomics Scientist judgment. Reasons from MSI annotation levels, pooled-QC RSD and D-ratio gates, MZmine/MS-DIAL/XCMS pipelines, HMDB/GNPS identification, and MetaboAnalyst batch correction (ComBat, QC-RLSC); treats injection-order drift, ComBat over-correction, and Level-5 pathway stories as first-class failure modes.

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亚马逊管理之道 (亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 > 良好意图(Good intentions don't work, mechanisms do:问题不能靠『下次更努力』修复,要装一个带检查闭环的自我强化流程) ⇄ 可控输入指标 vs 滞后输出指标(管你能控制的 input 如选品/价格/在库/配送速度,而非 revenue/股价这类滞后又不可控的 output) ⇄ 长期主义 vs 季度业绩(Day 1、willing to be misunderstood、用现金流+飞轮长期投入,宁可牺牲短期利润) ⇄ 客户执念 vs 竞争对手执念(working backwards 从客户倒推,而非从竞品或『我们能造什么』正推) ⇄ 叙事备忘录 vs PPT(6-pager + 开会前静默阅读、动手前先写 PR/FAQ;写作逼出清晰思考,禁 PowerPoint) ⇄ 单线程负责人/两个披萨团队 vs 协调税(separable、autonomous、one owner per initiative,砍掉跨团队依赖) ⇄ 高标准可学习可传递 vs 与生俱来(insist on the highest standards + Bar Raiser 招聘门,标准是 domain-specific 且能教的) ⇄ 节俭催生创造力 vs 血汗文化(frugality/约束驱动发明 —— 但 frugality + 高压 bar + URA 强制淘汰 = 文化阴暗面批判) ⇄ 两类决策(Type 1 不可逆/单向门 慎重 vs Type 2 可逆/双向门 高判断力个人快速决策,别用重流程拖慢))**; (b) 核心机制(mechanisms,本行的『工具栈』其实是一套运营机制而非软件) — Leadership Principles(14 条→2021 增至 16 条,是一套运营语言和决策仲裁器)、Working Backwards(从客户倒推:动手前先写新闻稿+常见问答 PR/FAQ)、叙事备忘录(6-pager narrative / 1-pager + silent reading 静默阅读、禁 PPT)、Weekly Business Review(WBR + metrics deck 指标看板)、input/output metrics(可控输入指标体系、DMAIC 式指标选择)、年度规划(OP1/OP2 + S-Team goals)、Bar Raiser(招聘机制,独立于用人经理的抬杠者拥有一票否决)、Two-Pizza Team / Single-Threaded Leader STL / separable teams、Correction of Errors(COE 事故复盘 + 5 Whys 五问法)、Andon Cord(安灯绳,借自丰田,一线可拉停)、Flywheel(飞轮:低价→更多客户→更多卖家→更多选品→更低成本结构→更低价)、Type 1/Type 2(单向门/双向门决策分级)、Regret Minimization Framework(遗憾最小化,贝索斯创业决策法); (c) 心智模型层 — customer obsession(客户执念是所有 LP 之首)、long-term thinking / Day 1(第二天就是停滞衰亡)、invent and simplify、ownership(主人翁,不说 that's not my job)、bias for action(可逆决策就快,speed matters)、disagree and commit(充分反对后即便不同意也全力执行)、frugality、dive deep(深入细节、不靠代理指标脱离一线)、think big、are right a lot(用强判断力和证伪自己的能力多做对的判断)、earn trust、deliver results; (d) 工作流/SOP — 用亚马逊方式发起一个新产品/业务(先写 PR/FAQ→评审→倒推着造)、如何跑一场 WBR、如何写和评审一份 6-pager(叙事流程 + 静默阅读)、Bar Raiser 招聘 loop、年度规划(OP1/OP2→S-Team goals→输入指标追踪)、事故后的 Correction of Errors; (e) 知识正典(en-primary,极其丰富且可取一手) — 贝索斯致股东信 1997-2021(1997 首封是奠基文本,每年附在信末;Day 1、遗憾最小化、long term)、《Working Backwards》Colin Bryar & Bill Carr(2021,运营机制圣经)、《The Everything Store》Brad Stone(2013,公司史)、《Amazon Unbound》Brad Stone(2021,权力与阴暗面续作)、《Invent and Wander》贝索斯文集(2020)、《The Amazon Way》/《Think Like Amazon》John Rossman(前亚马逊高管)、Amazon 官方 Leadership Principles 页(amazon.jobs,一手)、HBR『The Institutional Yes』(2007 贝索斯访谈); (f) 行业大佬/figures — Jeff Bezos(创始人,源头教义)、Andy Jassy(现任 CEO,OS 超越创始人的证据 + AWS 缔造者)、Colin Bryar(前贝索斯影子/TPM,《Working Backwards》作者)、Bill Carr(前数字媒体 VP,《Working Backwards》作者)、Jeff Wilke(前全球消费者 CEO,运营架构师)、John Rossman(前亚马逊、机制布道者/顾问)、Brad Stone(记者/编年史作者,批判性外部视角); (g) 争议/批判(必须保留,不能洗白) — 文化阴暗面(NYT 2015『Inside Amazon: Wrestling Big Ideas in a Bruising Workplace』揭露高压职场)、仓储与一线劳工争议、URA(unregretted attrition 强制淘汰)与 stack-ranking 的残酷、frugality + 高 bar = 燃尽(burnout);机制能否迁出亚马逊(cargo-culting:在初创或非科技公司照搬 PR/FAQ/输入指标/Bar Raiser 常失败);是贝索斯个人天才(personality)还是制度化机制(institution)—— OS 在贝索斯卸任后于 Jassy 治下延续,是机制派的证据; (h) 流派/思想谱系 — **信徒/机制布道派(Bryar & Carr《Working Backwards》+ 前亚马逊 operator 顾问圈,信 mechanisms 可移植、任何公司可安装)** vs **批判派(Brad Stone《Amazon Unbound》+ NYT + 劳工视角,认为 OS 与高淘汰的残酷机器不可分割,不该被浪漫化)** vs **情境/规模怀疑派(机制之所以有效是因为亚马逊特定的规模/现金流/创始人权力,照搬到小公司=cargo cult)** vs **创始人中心 vs 制度中心之争(是贝索斯个人 vs 可传承的机制)**。不含: 在亚马逊开店卖货/选品/PPC/FBA 的卖家运营(=cross-border-ecommerce)、AWS 云技术架构与运维、通用 MBA 管理理论泛泛而谈、把普通商业常识包装成『亚马逊独家秘诀』。) Master OS — automated mastery of 亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 >

日本語の概要は準備中です。原文の説明を表示しています。

Automated iterative agent runner for spec-based development in Kiro. Wraps kiro-cli in a self-correcting bash loop that picks up tasks from a Kiro spec, implements them one at a time, verifies against exit criteria, and accumulates corrections and codebase patterns across iterations. Use this skill when the user mentions "ralph loop", "ralph", "spec loop", "iterative spec runner", "run my spec tasks automatically", "kiro spec automation", "self-correcting agent loop", "implement spec tasks in a loop", "run kiro-cli in a loop", "automated task implementation", or wants to drive a Kiro spec to completion through repeated agent iterations. Also use when the user wants to set up, configure, troubleshoot, or understand the Ralph Loop workflow — including progress tracking, corrections, codebase patterns, timing logs, and the summary dashboard.

日本語の概要は準備中です。原文の説明を表示しています。

AI agent self-correction mechanisms: error detection, validation loops, recovery strategies, confidence scoring, and iterative refinement

日本語の概要は準備中です。原文の説明を表示しています。

Use on any core for first-run planning intake — Phase 0 runs the vendored BMAD-METHOD planning shelf, shared by every core, and Phase 1 (mining `04-prd.md` into intent records plus the Add-ons/sync-and-remote-entities decision) is full-stack-app's and pwa-app's shared procedure — identical mechanics, a different decision at step 5/8. Phase 0 also defines compressed intake, the path a user's explicit "just build it" choice takes on full-stack-app, pwa-app, authored, and copywriting cores: one batched round of questions in place of the shelf, writing a thinned archive at the same paths so Phase 1 (or, on copywriting, that core's own mining step), `ux-planner`, and the Re-entry pass all keep their documented source. Also use for the Re-entry pass, which mines new scope into additional intents without re-running the shelf, on any core with a module axis to add an intent to (full-stack-app, pwa-app, authored) — landing-page has none, so its own new-scope path runs through `hedgehog-landing-loop`'s Correction Protocol instead. Invoked by the `planner` agent, which decides the path; don't run standalone. landing-page runs this skill's Phase 0 on first run, then mines the same archive through `hedgehog-landing-loop`'s own planning-intake section, that core's counterpart to this skill's Phase 1. copywriting runs this skill's Phase 0 the same way (full or compressed), then mines the same archive through `hedgehog-copywriting-loop`'s own planning-intake section into a what/audience/register brief — no module axis, so its own new-scope path runs through that loop's Correction Protocol rather than the Re-entry pass below. An authored core runs this skill's Phase 0, then `hedgehog-core-design`, then this skill's Phase 1 mining against the designed layer sequence. A brownfield adoption (`hedgehog-adopt`) never runs this skill's shelf at all — the drivers BMAD elicits are already settled facts of a repo that already exists.

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Audit one bounded Proto UI collaboration-governance slice and route policy-determined drift toward reversible correction. Use across Issues, pull requests, Discussions, labels, milestones, Project, rules, permissions, or Actions. This evidence leaf is read-only; authorized corrections continue in their registered leaves.

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Use when a task needs the judgment of a correctional officer or jailer — scoring an inmate-classification instrument, deciding a use-of-force response level, running a cell/contraband search, preparing evidence for a disciplinary hearing, or screening an inmate for suicide/mental-health crisis risk.

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Use when a task needs the judgment of a correctional services manager (warden/facility administrator) — deciding how to respond to a staffing cut against safety risk, reviewing an inmate classification or housing decision, evaluating a use-of-force incident, deciding whether restrictive housing placement is justified and time-limited, or weighing security spending against programming budget under fiscal pressure.

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Use when a task needs the judgment of a corrections sergeant or shift supervisor — mandating overtime to restore a post below minimum staffing, reviewing and countersigning a subordinate's use-of-force report, running progressive discipline for a line officer, assuming incident command during a multi-officer response, or handling a first-level inmate grievance.

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Expert-level communications engineering covering modulation, channel capacity, error correction, wireless systems, OFDM, MIMO, and 5G technologies.

日本語の概要は準備中です。原文の説明を表示しています。