Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for microbiome analysis.
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Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for microbiome analysis.
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Look up Y Combinator companies and batches from the public yc-oss API, a static JSON dataset refreshed daily: company profiles, batch rosters (e.g. W25, S24), companies by industry or tag, top companies, who is hiring, founder-diversity lists, and overall YC stats. Use this skill whenever the user asks about YC-backed startups, a YC batch, YC companies in a sector or tag or that are hiring, the Y Combinator portfolio, or startup and venture research that draws on YC data. Read-only.
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Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
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Visualize metagenomic profiles using R (phyloseq, microbiome) and Python (matplotlib, seaborn). Create stacked bar plots, heatmaps, PCA plots, and diversity analyses. Use when creating publication-quality figures from MetaPhlAn, Bracken, or other taxonomic profiling output.
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Generate dark-mode-compatible inline SVG data visualization charts for blog posts. Supports horizontal bar, grouped bar, donut, line, lollipop, area, and radar charts with automatic platform detection (HTML vs JSX/MDX). Enforces chart type diversity, accessible markup (role=img, aria-labelledby), source attribution, and transparent backgrounds. Use when user says "blog chart", "generate chart", "data visualization", "svg chart", "blog graph", or "visualize data".
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Audit and score blog posts on a 5-category 100-point scoring system covering content quality, SEO optimization, E-E-A-T signals, technical elements, and AI citation readiness. Includes AI content detection (burstiness, phrase flagging, vocabulary diversity). Supports export formats (markdown, JSON, table) and batch analysis with sorting. Generates prioritized recommendations (Critical/High/Medium/Low) with specific fixes. Works with any format (MDX, markdown, HTML, URL). Use when user says "analyze blog", "audit blog", "blog score", "check blog quality", "blog review", "rate this blog", "blog health check".
日本語の概要は準備中です。原文の説明を表示しています。
Generate dark-mode-compatible inline SVG data visualization charts for blog posts. Supports horizontal bar, grouped bar, donut, line, lollipop, area, and radar charts with automatic platform detection (HTML vs JSX/MDX). Enforces chart type diversity, accessible markup (role=img, aria-labelledby), source attribution, and transparent backgrounds. Use whenever the user mentions data visualization, charts, graphs, comparison tables that need to be visualized, or wants to embed inline SVG visualizations in a blog post, even if not invoking blog-write. Use when user says "blog chart", "generate chart", "data visualization", "svg chart", "blog graph", "visualize data", or when the blog-write workflow identifies chart-worthy data points (3+ comparable metrics, trends, before/after data).
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Draft Diversity, Equity, and Inclusion statements for academic applications.
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Detects overlooked, underrepresented, weakly resolved, or poorly validated populations and subgroups within a biomedical research area so users can identify more precise and meaningful study populations. Always use this skill when the real question is not just what is under-studied, but which populations, strata, or subgroups are missing, thinly represented, superficially analyzed, pooled without resolution, or insufficiently validated in the current evidence base. Focus on meaningful subgroup gaps rather than generic calls for diversity.
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Cross-encoder reranking and MMR diversity filtering for improved retrieval quality
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Capture a user's real writing voice from 5-20 prior samples, store a local voice.yaml fingerprint, and enforce it on newsjack drafts so AI tells disappear. Measures voice with named stylometry lenses (Burrows's Delta function-word vector, MATTR lexical diversity, sentence-length burstiness, Biber Dimension-1 register, opener-POS profile, punctuation rates) and gates drafts against the fingerprint as bands, not vibes.
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Assembles microbial-community sequencing into metagenome-assembled genomes (MAGs) with metaFlye (ONT), metaSPAdes/MEGAHIT (Illumina), and hifiasm-meta/metaMDBG (PacBio HiFi), then recovers genomes via multi-binner consolidation (MetaBAT2, MaxBin2, CONCOCT, SemiBin2, VAMB -> DAS_Tool) and QCs them against MIMAG with CheckM2, GUNC, and GTDB-Tk. Covers why a metagenome is not a genome (uneven coverage, micro-diversity, strain collapse to consensus), differential-coverage binning, co-assembly vs per-sample, the rRNA-operon collapse that fails short-read MAGs, and strain resolution with inStrain. Use when reconstructing genomes from a microbiome, soil, ocean, or gut community, recovering MAGs, or resolving strain-level variation.
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Infers person-to-person transmission from pathogen genomes using outbreaker2, TransPhylo, phybreak, BadTrIP, SCOTTI, BEASTLIER, and SNP-distance / cluster-picker approaches (HIV-TRACE for HIV; transcluster). Defines outbreak clusters using pathogen-specific SNP thresholds (NOT a universal cutoff -- TB <=12 SNPs; MRSA <=15; C. difficile <=2; Klebsiella <=21), models within-host diversity and transmission bottlenecks, integrates contact-tracing data, distinguishes generation from serial interval, and attributes source via Bayesian source attribution (islandR). Use when investigating outbreaks for who-infected-whom, defining SNP-cluster outbreak definitions, accounting for unsampled intermediates, choosing between outbreaker2 (rich epi data) and TransPhylo (genomic-only after a dated phylogeny), running source attribution between host populations, calling HIV-TRACE thresholds appropriate to the local subtype, or distinguishing recent transmission from reactivation in TB or chronic HIV.
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Search runtime and scene management: verify queries, inspect scenes, debug app readiness, and diagnose recall or scene-config issues.
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Summarize a sprint's worth of Claude Code activity — sessions grouped by project (cwd), per-model cost breakdown, token efficiency (cache hit rate, compaction baselines), subagent effectiveness from workflow API, velocity metrics (turn_count, turn_duration_ms), and tool diversity across the sprint.
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Pre-send quality scorecard for any lead list. Grades duplicate rate, title diversity, bad-title patterns, catch-all domain density, ICP fit, email verification coverage. Outputs a letter grade + action items BEFORE you send. Catches bad lists before they burn inboxes. Run after email enrichment, before Smartlead upload.
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Review criteria for the nw-diverger-reviewer — validates JTBD rigor, research quality, option diversity, taste application correctness, and recommendation coherence in DIVERGE wave artifacts
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Structured divergent thinking techniques — HMW framing, SCAMPER, Crazy 8s mechanics, and option diversity guarantees. Enforces strict separation of generation and evaluation phases.
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Audits existing tests in any language using formal, research-backed test smell names and the testsmells.org 19-smell academic taxonomy. Use when the caller asks for an academic or citable test-smell review, named smell categories, or a formal severity-ranked smell assessment. Covers Assertion Roulette, Conditional Test Logic, Mystery Guest, Eager Test, Sleepy Test, Unknown Test, Sensitive Equality, and the rest of the catalog across .NET, Python, JavaScript/TypeScript, Java, Go, Ruby, Rust, Swift, Kotlin, PowerShell, and C++. DO NOT USE FOR a quick pragmatic test review (use test-anti-patterns), writing or running tests, framework migration, coverage, or assertion-diversity metrics.
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Pythonic RDKit wrapper with sensible defaults for drug discovery. SMILES parsing, standardization, descriptors, fingerprints, similarity, clustering, diversity selection, scaffold analysis, BRICS/RECAP fragmentation, 3D conformers, and visualization. Returns native rdkit.Chem.Mol. Prefer datamol for standard workflows; use RDKit directly for advanced control.
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Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.
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Generate diverse solution candidates with category-spanning ideation methods and rotation. Use when stuck on a design or fighting repetitive LLM output.
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Design privacy-preserving analytics systems using differential privacy, k-anonymity, l-diversity, and t-closeness. Covers privacy budget allocation with epsilon tracking, references Google DP library, OpenDP, and Apple PPML. Includes Python differential privacy implementation for GDPR-compliant statistical analysis.
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Evaluates anonymization as a retention alternative under GDPR Recital 26, applying the WP29 Opinion 05/2014 techniques including randomization and generalization. Validates anonymization effectiveness using k-anonymity, l-diversity, and t-closeness metrics. Activate for anonymization, de-identification, k-anonymity, retention alternative queries.
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