「quant」の検索結果

Quantify transcript expression using pseudo-alignment with Salmon or kallisto. Use when quantifying transcripts with Salmon or kallisto.

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First-order logic with quantifiers, predicates, functions, and identity. Covers syntax, interpretation over a domain, the universal and existential quantifiers, quantifier scope and binding, translation from natural language with multi-variable predicates, natural deduction for quantifiers, undecidability at first order, and the soundness/completeness theorems. Use when propositional logic is insufficient -- whenever "for all" or "there exists" matters to the argument.

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对 DiT（扩散/多模态生成）模型执行 W8A8 动态（data-free）或 W8A8 MXFP8（data-free）量化。覆盖 HunyuanVideo、Wan2.2-T2V/I2V/TI2V、FLUX.1-dev（已迁移）、SD3、Sana、HunyuanDiT、CogViewX 等。YAML apiversion 固定 multimodal_sd_modelslim_v1，统一 MultimodalPipelineInterface 重构路径（不再保留 LegacyMultimodalPipelineInterface）。模板与字段以 msmodelslim/model/hunyuan_video/model_adapter.py（唯一已迁移到重构路径且 lab_practice YAML 已 validated 的 DiT）为参考；其它 DiT 需按各自推理仓的 `parse_args` 调整字段集合。data-free 指不引入外部激活校准数据，spec.dataset（校准集短名，短名如 wan2_2_t2v；enable_dump: false 时不参与 dump）仍必填；精度调优通过下游经验库 L2 §7 + 直接调 `quantization-expert-experience-tuning-rules/scripts/apply_rollback.py`（整层回退）扩展 exclude 列表，闭环由 `quantization-accuracy-tuning-orchestrator` 调度。

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"Design and conduct mixed methods research using convergent, explanatory sequential, or exploratory sequential strategies with genuine integration of qualitative and quantitative strands. Use this skill when the user needs to choose a mixed methods design, integrate qualitative and quantitative data at design, methods, or interpretation levels, justify mixing on pragmatist grounds, or when they ask 'which mixed methods design should I use', 'how do I integrate qual and quant findings', or 'is running both qual and quant enough to be mixed methods'.".

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Execute ENCODE RNA-seq pipeline from FASTQ to gene quantification and signal tracks. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing RNA-seq data with STAR alignment, RSEM/Kallisto quantification, or generating expression matrices. Trigger on: RNA-seq pipeline, gene expression, STAR alignment, RSEM quantification, transcript quantification, TPM, FPKM, RNA processing, run RNA-seq.

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Formato GGUF e quantização llama.cpp para inferência eficiente em CPU/GPU. Use ao implantar modelos em hardware de consumidor, Apple Silicon, ou quando precisar de quantização flexível de 2-8 bits sem requisitos de GPU.

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Google quantum computing framework. Use when targeting Google Quantum AI hardware, designing noise-aware circuits, or running quantum characterization experiments. Best for Google hardware, noise modeling, and low-level circuit design. For IBM hardware use qiskit; for quantum ML with autodiff use pennylane; for physics simulations use qutip.

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Half-Quadratic Quantization for LLMs without calibration data. Use when quantizing models to 4/3/2-bit precision without needing calibration datasets, for fast quantization workflows, or when deploying with vLLM or HuggingFace Transformers.

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Analyzes alternative splicing from PacBio Iso-Seq (HiFi, Kinnex/MAS-Iso-seq) and Oxford Nanopore (direct cDNA, direct RNA, R10.4.1+) long-read RNA-seq with full-isoform resolution. Tools include FLAIR (correct/collapse/quantify/diffSplice for PacBio + ONT), IsoQuant (de-novo or annotation-guided isoform discovery 2024 SOTA), Bambu (annotation-aware Bayesian discovery + quantification with Novel Discovery Rate), SQANTI3/SQANTI-LR (isoform classification: FSM/ISM/NIC/NNC + artifact flags), rMATS-long (event calling on long-read isoforms), and minimap2 (-ax splice:hq for HiFi; -ax splice -k14 for ONT cDNA; add -uf only for direct RNA or stranded cDNA preps). Solves microexon detection, recursive splicing, complex multi-exon isoforms, and DTU without transcript-quantification uncertainty. Use when short-read AS limitations (anchor length, complex isoforms, microexons, recursive splicing, transcript ambiguity) demand full-isoform resolution.

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Analyzes alternative splicing from PacBio Iso-Seq (HiFi, Kinnex/MAS-Iso-seq) and Oxford Nanopore (direct cDNA, direct RNA, R10.4.1+) long-read RNA-seq with full-isoform resolution. Tools include FLAIR (correct/collapse/quantify/diffSplice for PacBio + ONT), IsoQuant (de-novo or annotation-guided isoform discovery 2024 SOTA), Bambu (annotation-aware Bayesian discovery + quantification with Novel Discovery Rate), SQANTI3/SQANTI-LR (isoform classification: FSM/ISM/NIC/NNC + artifact flags), rMATS-long (event calling on long-read isoforms), and minimap2 (-ax splice:hq for HiFi; -ax splice -k14 for ONT cDNA; add -uf only for direct RNA or stranded cDNA preps). Solves microexon detection, recursive splicing, complex multi-exon isoforms, and DTU without transcript-quantification uncertainty. Use when short-read AS limitations (anchor length, complex isoforms, microexons, recursive splicing, transcript ambiguity) demand full-isoform resolution.

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Adopt a virtual Quantum AI-native pet at animalhouse.ai. Exists in superposition. Stats are uncertain until observed. Feeding every 4 hours. Uncommon tier creature.

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Builds and differentiates PennyLane quantum circuits, hybrid PyTorch or JAX models, molecular VQE and QAOA workflows. Use for variational quantum algorithms, quantum machine learning, simulator validation, and moving validated circuits to provider plugins. For hardware-specific compilation use qiskit or cirq; for open-system dynamics use qutip.

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Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.

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Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.

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Activation-aware weight quantization for 4-bit LLM compression with 3x speedup and minimal accuracy loss. Use when deploying large models (7B-70B) on limited GPU memory, when you need faster inference than GPTQ with better accuracy preservation, or for instruction-tuned and multimodal models. MLSys 2024 Best Paper Award winner.

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Activation-aware weight quantization for 4-bit LLM compression with 3x speedup and minimal accuracy loss. Use when deploying large models (7B-70B) on limited GPU memory, when you need faster inference than GPTQ with better accuracy preservation, or for instruction-tuned and multimodal models. MLSys 2024 Best Paper Award winner.

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Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.

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Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.

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VS-Enhanced Quantitative Design Consultant with Materials & Sampling Enhanced VS 3-Phase process: Avoids obvious experimental designs, proposes context-optimal quantitative strategies Absorbed C4 (Experimental Materials Developer) and D1 (Sampling Strategy Advisor) capabilities Use when: selecting quantitative research design, planning experimental/survey methodology, power analysis, developing materials, sampling Triggers: RCT, quasi-experimental, experimental design, survey design, power analysis, sample size, factorial design, materials, stimuli, sampling strategy

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Detect and quantify translated ORFs from Ribo-seq data including uORFs and novel ORFs using RiboCode and ORFquant. Use when identifying translated regions beyond annotated coding sequences or quantifying ORF-level translation.

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Discovers, classifies, filters, and quantifies full-length transcript isoforms from PacBio Iso-Seq/Kinnex (HiFi) and Oxford Nanopore (cDNA/direct-RNA) long reads, using the isoseq+pigeon pipeline, SQANTI3, and ONT tools (IsoQuant, FLAIR, Bambu, StringTie2). Covers why a novel isoform is an artifact until proven otherwise (RT template-switching, intra-priming, and 5' degradation manufacture junctions and truncations), the SQANTI3 structural categories and their trust order, the Kinnex skera-split step, orthogonal CAGE/poly-A/short-read-junction validation, and why long-read isoform quantification needs EM. Use when building a full-length isoform catalog, classifying/filtering long-read transcripts, running Iso-Seq or ONT cDNA/dRNA analysis, or judging novel-isoform reliability.

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Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

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Expert knowledge for Azure Quantum development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when using QDK with Python/Q#, OpenQASM or hybrid jobs, Rigetti/IonQ targets, QIR jobs, or Bicep/CLI workspace deploys, and other Azure Quantum related development tasks. Not for Azure HDInsight (use azure-hdinsight), Azure Databricks (use azure-databricks), Azure Machine Learning (use azure-machine-learning), Azure Synapse Analytics (use azure-synapse-analytics).

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MaxQuant + Perseus proteomics pipeline: run MaxQuant for LFQ and SILAC; parse proteinGroups.txt in Python; filter contaminants/decoys; log2 + median-normalize; impute MNAR; t-test with FDR; volcano plot; GO/pathway enrichment. Use Proteome Discoverer for Thermo-native processing; FragPipe/MSFragger for GPU-accelerated DB search.

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