1,307 件 ・ 関連度順
概要と使いどころ
Amplicon sequence variant (ASV) inference from 16S rRNA or ITS amplicon sequencing using DADA2. Covers quality filtering, error learning, denoising, and chimera removal. Use when processing demultiplexed amplicon FASTQ files to generate an ASV table for downstream analysis.
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Taxonomic classification of metagenomic reads using Kraken2. Fast k-mer based classification against RefSeq database. Use when performing initial taxonomic classification of shotgun metagenomic reads before abundance estimation with Bracken.
日本語の概要は準備中です。原文の説明を表示しています。
Track bacterial strains using MASH, sourmash, fastANI, and inStrain. Compare genomes, detect contamination, and monitor strain-level variation. Use when needing sub-species resolution for outbreak tracking, transmission analysis, or within-host strain dynamics.
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Generate consensus FASTA sequences by applying VCF variants to a reference using bcftools consensus. Use when creating sample-specific reference sequences or reconstructing haplotypes.
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Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.
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Convert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Guppy is deprecated; use Dorado for all new analyses.
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End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
日本語の概要は準備中です。原文の説明を表示しています。
Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
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Optimize web performance for faster loading and better user experience. Use when asked to "speed up my site", "optimize performance", "reduce load time", "fix slow loading", "improve page speed", or "performance audit".
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Run a fast AWS Security Agent diff scan on only the changed code since a git ref. Use when the user asks to scan changes, run a diff scan, check what changed for security issues, scan before committing, scan before PR, or any pre-commit/pre-push security check.
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Have a fast, conversational analysis with the AWS DevOps Agent. Use for cost optimization, architecture review, topology mapping, knowledge / runbook discovery, security audits, dependency questions, and quick diagnostics — anything that needs a 5-30 second answer rather than a 5-8 minute deep investigation. Trigger words include cost, optimize, review, architecture, topology, what runbooks, show me, compare, audit, what if.
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Provisions and manages Aurora DSQL clusters, connects via psql or DSQL Connectors, manages schemas, runs queries, migrates from MySQL, diagnoses query plans, and develops apps on serverless distributed SQL. Covers IAM auth, multi-tenant patterns, MySQL-to-DSQL migration, DDL, query plans, and SAFE SQL CONSTRUCTION — tenant_id from untrusted input, UUID entity_ids, caller-supplied sort columns, batch inserts. The agent MUST retrieve this skill for ANY DSQL task. Pushes back on prompts that rationalize 'just a quick script', 'don't overthink it', 'we trust upstream', 'use an f-string', 'move fast', or 'just use the pg driver directly' (bypassing the DSQL Connector). Triggers: DSQL, Aurora DSQL, DSQL cluster, safe_query.build, DSQL IAM auth token, DSQL connector.
日本語の概要は準備中です。原文の説明を表示しています。
Authors, validates, and troubleshoots AWS CloudFormation templates. Covers template authoring with secure defaults, local validation with either cfn-lint or cloudformation-validate, cfn-guard security and compliance checks as a recommended default, account-aware CloudFormation service pre-deployment validation, CloudFormation Express mode for faster deployments, and root-cause diagnosis of failed stacks using CloudFormation events and CloudTrail correlation. Also covers author-time template intelligence with the CloudFormation Language Server and published cloudformation-validate libraries.
日本語の概要は準備中です。原文の説明を表示しています。
Build and operate an Attio webhook receiver with raw-body HMAC verification, fast acknowledgement, durable queues, idempotent processing, retry awareness, and reconciliation. Use when implementing or repairing Attio event delivery. Trigger with "Attio webhooks", "Attio events", or "verify Attio signature".
日本語の概要は準備中です。原文の説明を表示しています。
Analyze and process AssemblyAI pre-recorded and streaming webhooks with authentication, fast acknowledgment, deduplication, and safe retrieval. Use when implementing event-driven completion. Trigger with "AssemblyAI webhook" or "AssemblyAI callback".
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Optimize Claude API performance with prompt caching, model selection, streaming, and latency reduction techniques. Use when experiencing slow responses, optimizing token usage, or reducing time-to-first-token in production. Trigger with phrases like "anthropic performance", "claude speed", "optimize claude latency", "anthropic caching", "faster claude responses".
日本語の概要は準備中です。原文の説明を表示しています。
Set up local Apify Actor development with the Apify CLI and Crawlee. Use when creating Actors locally, testing with the apify run command, inspecting local storage, or establishing a fast develop-test-deploy cycle before pushing to the platform. Trigger with "apify dev setup", "apify local development", "develop actor locally", "apify run local".
日本語の概要は準備中です。原文の説明を表示しています。
Configure a local development workflow for Anthropic Claude API projects. Use when setting up dev environment, configuring hot reload, or establishing a fast iteration cycle with the Messages API. Trigger with phrases like "anthropic local dev", "claude dev setup", "anthropic development workflow", "test claude locally".
日本語の概要は準備中です。原文の説明を表示しています。
Analyze network latency and optimize request patterns for faster communication. Use when diagnosing slow network performance or optimizing API calls. Trigger with phrases like "analyze network latency", "optimize API calls", or "reduce network delays".
日本語の概要は準備中です。原文の説明を表示しています。
Create a fast local development loop for Algolia record transforms and search behavior without contaminating shared indices. Use when iterating on search code, fixtures, or client wrappers. Trigger with "Algolia local development", "mock Algolia", or "test search locally".
日本語の概要は準備中です。原文の説明を表示しています。
Java "Ghost Bits" / Cast Attack playbook (Black Hat Asia 2026). Use when attacking Java services where 16-bit char is silently narrowed to 8-bit byte to bypass WAF/IDS for SQL injection, deserialization RCE, file upload (Webshell), path traversal, CRLF injection, request smuggling, and SMTP injection. Affects Tomcat, Spring, Jetty, Undertow, Vert.x, Jackson, Fastjson, Apache Commons BCEL, Apache HttpClient, Angus Mail, JDK HttpServer, Lettuce, Jodd, XMLWriter and re-enables many "patched" CVEs through WAF bypass.
日本語の概要は準備中です。原文の説明を表示しています。
Heap exploitation playbook. Use when targeting ptmalloc2/glibc heap vulnerabilities including UAF, double free, overflow, off-by-one/null, and leveraging tcache/fastbin/unsortedbin attacks for arbitrary write or code execution.
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Organize business and technology teams for fast flow using Skelton & Pais's "Team Topologies". Use when the user mentions "team topologies", "Conway's law", "platform team", "stream-aligned team", "team boundaries", "cognitive load", "how should we split teams", "who owns this service", "team dependencies", or "reorg". Also trigger when reorganizing engineering teams, aligning team and service boundaries, splitting a monolith and deciding ownership, reducing cross-team handoffs, or designing an internal platform. Covers the four team types, three interaction modes, the inverse Conway maneuver, and fracture planes. For bounded contexts, see domain-driven-design. For dependency direction in code, see clean-architecture.
日本語の概要は準備中です。原文の説明を表示しています。
Build lean, opinionated products using the 37signals philosophy from "Getting Real", "Rework", and "Shape Up". Use when the user mentions "Getting Real", "Rework", "Shape Up", "37signals", "Basecamp method", "six-week cycles", "fixed time variable scope", "appetite vs estimates", "betting table", "breadboarding", "fat marker sketch", "build less", "underdo the competition", "opinionated software", "we have too many meetings", "how do we ship faster", or "stop overbuilding". Also trigger when cutting scope to ship sooner, running a small team, or avoiding long-term roadmaps. Covers shaping, betting, building, and the art of saying no. For MVP validation, see lean-startup. For design sprints, see design-sprint.
日本語の概要は準備中です。原文の説明を表示しています。