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Identify tumor neoantigens from somatic variants with pVACtools (pVACseq/pVACfuse/pVACbind/pVACvector/pVACview) for personalized cancer vaccines and checkpoint biomarkers. Encodes the field's hard truth that binding prediction is the easy, near-solved part and single-digit-percent PPV lives downstream — so it centers clonality/CCF, HLA LOH (the silent invalidator), expression, proximal-variant phasing, agretopicity/foreignness quality, and the predicted->presented->immunogenic validation tiers. Use when nominating vaccine targets, ranking neoantigens, or building a tumor-to-candidate pipeline. Binding details in mhc-binding-prediction; ranking in immunogenicity-scoring.

日本語の概要は準備中です。原文の説明を表示しています。

Compact the session into gitignored `.codeconductor/sessions/handoff.md` (redact secrets).

日本語の概要は準備中です。原文の説明を表示しています。

Writing style guide for technical content, social media, blog posts, READMEs, git commits, and developer documentation. Optimized to avoid AI detection patterns. Use when writing any content beyond code.

日本語の概要は準備中です。原文の説明を表示しています。

Prepare a private handoff to continue a task in Claude Code, Codex, or another agent; resume from an existing handoff without changing Git or executing its commands automatically. Use for "continue in Codex", "pasar a Claude", "migrar esta sesión", or "retomar este handoff".

日本語の概要は準備中です。原文の説明を表示しています。

Generate user-facing App Store release notes from git history since the last tag.

日本語の概要は準備中です。原文の説明を表示しています。

Orchestrate autonomous AI development pipelines through your Kanban board (Asana, GitHub Projects, Linear). Manages multi-worker Claude Code dispatch, deterministic quality gates, adversarial review, per-task cost tracking, and crash-proof pipeline execution.

日本語の概要は準備中です。原文の説明を表示しています。

Extract AmeriFlux site metadata and map it to EcoSIM JSON variables. Use when a task needs site latitude, longitude, elevation, mean annual temperature, Koppen climate code, or vegetation type for an AmeriFlux site ID or flux-site name.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when you need to derive a Koppen-Geiger climate label from input latitude and longitude, then convert between the letter code such as `Csa` and the EcoSIM-style numeric code such as `34`.

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Download NASA GES DISC NLDAS_FORA0125_H version 2.0 primary hourly forcing data for a point location. Use when Codex needs to retrieve NLDAS File A meteorological forcing from the GES DISC API or HTTPS archive for a longitude/latitude pair, including Earthdata username/password authentication, hourly URL generation, nearest-grid-point extraction, CSV output, or EcoSIM climate-forcing preprocessing.

日本語の概要は準備中です。原文の説明を表示しています。

Extract point-scale CMIP6 historical and SSP future climate data from the Pangeo Google Cloud catalog and convert them into bias-corrected additive or multiplicative anomalies for LSM or EcoSIM climate forcing. Use when a task needs site latitude/longitude, scenario-specific CMIP6 variables, vapor pressure derived from huss and ps, calendar-aware day-of-year climatologies, or projected change summaries for the 2050s and 2090s.

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Download Copernicus CDS ERA5 single-level point time-series climate forcing for non-US or non-NLDAS EcoSIM sites from longitude/latitude coordinates. Use when a paper-derived site is outside the NLDAS domain, lacks AmeriFlux/FLUXNET curated forcing, or needs global ERA5 variables such as 2m temperature, dewpoint temperature, surface pressure, solar radiation, precipitation, and 10m wind components for EcoSIM preprocessing.

日本語の概要は準備中です。原文の説明を表示しています。

Convert AmeriFlux ERA5 half-hourly meteorological CSV files into EcoSIM hourly climate forcing NetCDF files, compare generated forcing against overlapping measured tower meteorology when a FULLSET file is available, and report large biases or errors. Use when preparing or validating EcoSIM climate inputs for AmeriFlux sites, checking ERA5 against in situ records, diagnosing forcing discrepancies, or writing climate-quality reports. For non-AmeriFlux paper sites that need a fresh Copernicus CDS ERA5 point download by longitude/latitude, use era5-cds-point-download first.

日本語の概要は準備中です。原文の説明を表示しています。

Supply chain investigation, evidence recovery, and forensic analysis for GitHub repositories. Covers deleted commit recovery, force-push detection, IOC extraction, multi-source evidence collection, hypothesis formation/validation, and structured forensic reporting. Inspired by RAPTOR's 1800+ line OSS Forensics system.

日本語の概要は準備中です。原文の説明を表示しています。

Delegate coding tasks to OpenAI Codex CLI agent. Use for building features, refactoring, PR reviews, and batch issue fixing. Requires the codex CLI and a git repository.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants to review a pull request, understand what a PR changes, assess risk of merging, or check for missing test coverage. Examples: "Review this PR", "What does PR #42 change?", "Is this PR safe to merge?"

日本語の概要は準備中です。原文の説明を表示しています。

Analyze blast radius before making code changes

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The PRIMARY development workflow for the Archon project (remote-coding-agent). Use this skill instead of any PRP skills when working on Archon code. Routes to 10 specialized cookbooks based on what the user is trying to do: RESEARCH — "how does the orchestrator work?", "where is session state defined?", "trace the workflow execution flow", "what is IWorkflowStore?" INVESTIGATE — "should we use Drizzle or Prisma?", "what's the best way to add WebSockets?", "can we migrate to Turso?", "how do other projects handle rate limiting?" PRD — "write a PRD for dark mode", "spec out the notification feature", "product requirements for webhook retry" PLAN — "plan the auth refactor", "design the caching layer", "create an implementation plan for #42" IMPLEMENT — "implement the plan", "execute .claude/archon/plans/auth.plan.md", "build the feature from the plan", "code this up" REVIEW — "review PR #123", "review my changes", "code review the diff" DEBUG — "debug the failing test", "why is streaming broken?", "root cause analysis on the timeout issue" COMMIT — "commit these changes", "commit the auth refactor" PR — "create a PR", "open a pull request for this branch" ISSUE — "report this to gh", "create a gh issue", "log it in github", "file a bug for this", "create a feature request" This skill triggers on ANY development task: researching, investigating, planning, building, reviewing, debugging, committing, or shipping code. NOT for: Running Archon CLI workflows in worktrees (use /archon instead).

日本語の概要は準備中です。原文の説明を表示しています。

Use when: User wants to run Archon workflows, CREATE workflows or commands, set up Archon, or manage Archon configuration. Triggers (run): "use archon to", "run archon", "archon workflow", "use archon for", "have archon", "let archon", "ask archon to". Triggers (create): "create a workflow", "write a workflow", "make a command", "author a workflow", "new workflow", "new command", "archon workflow yaml". Triggers (setup): "set up archon", "install archon", "how to use archon", "configure archon", "archon setup", "get started with archon". Triggers (config): "change my archon config", "modify archon config", "archon config", "change archon settings", "update my config", "help me change my config", "edit archon config", "archon configuration". Triggers (init): "initialize archon", "set up .archon", "archon init", "add archon to repo". Capability: Runs AI workflows in isolated git worktrees for parallel development. Also: Creates and manages workflow YAML files, command files, and configuration. NOT for: Direct Claude Code work - only for delegating to Archon CLI.

日本語の概要は準備中です。原文の説明を表示しています。

Plan safe refactors using blast radius and dependency mapping

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Use when: User wants to extend Docker with custom tools, personalize the Docker environment, or set up user-specific Docker customization. Triggers: 'extend docker', 'docker-extend', 'add tools to docker', 'customize docker', 'add my tools to the container', 'personalize docker setup', 'docker user setup', 'install tools in docker'. Does: Interactively sets up Dockerfile.user and docker-compose.override.yml so users can add personal tools to their Docker environment without affecting maintainer files or committing user-specific config to git.

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Use when the user wants to rename, extract, split, move, or restructure code safely. Examples: "Rename this function", "Extract this into a module", "Refactor this class", "Move this to a separate file"

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Use when the user wants to know what will break if they change something, or needs safety analysis before editing code. Examples: "Is it safe to change X?", "What depends on this?", "What will break?"

日本語の概要は準備中です。原文の説明を表示しています。

Trace bugs through call chains using knowledge graph

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Triage GitHub issues by applying type, effort, priority, and area labels. Runs in an isolated context to avoid polluting the main conversation with issue details. Delegates to a specialized triage agent with label validation hooks.

日本語の概要は準備中です。原文の説明を表示しています。