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Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017 successor to bPTP; bPTP is Python NOT R), GMYC single/multi-threshold (Pons 2006; Fujisawa 2013), multilocus BPP v4 with prior calibration from data (NOT defaults; Yang 2015), SNAPP + BFD* for SNP delimitation, DELINEATE (Sukumaran 2021) speciation-process modeling to address Sukumaran & Knowles 2017 PNAS critique that MSC delimits structure not species, integrative-taxonomy congruence (Padial 2010; Carstens 2013), Dsuite for introgression testing before sister claims (Malinsky 2021), and Meyer & Paulay 2005 barcoding-gap-absence caveat. Use when delineating species from DNA barcoding data, resolving cryptic complexes, choosing among ASAP/mPTP/BPP/DELINEATE, calibrating BPP priors, distinguishing introgression from ILS, or applying the Sukumaran-Knowles oversplitting correction.

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Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers. Covers bottleneck math (250x cells/sgRNA requires ~25M cells implanted; impossible for most syngeneic models, forcing focused libraries), focused library design (Manguso 2017 Nature 547:413 immune screen; Chen 2015 tumor screens), CRISPR-StAR intrinsic-control screening (Uijttewaal 2025 Nat Biotechnol 43:1848), clonal-dynamics-limited detection, tumor-explant DNA recovery, syngeneic vs xenograft vs PDX considerations, and the relationship to downstream MAGeCK / drugZ analysis. Use when designing in vivo CRISPR screens for tumor / immune / metastasis biology, choosing focused vs genome-wide for animal models, addressing bottleneck-induced clonal collapse, picking the syngeneic / xenograft / PDX model, integrating in vivo with in vitro results, or applying CRISPR-StAR for animal experiments.

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[02] META. Create new skills when existing ones don't cover the task. Analyze unique requirements, build framework (Frame → Research → Plan → Execute), integrate risks, and declare new skill. Use when facing novel problems that existing skills can't address.

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Azure Maps SDK for .NET. Location-based services including geocoding, routing, rendering, geolocation, and weather. Use for address search, directions, map tiles, IP geolocation, and weather data.

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Find nearby places (restaurants, cafes, bars, pharmacies, etc.) using OpenStreetMap. Works with coordinates, addresses, cities, zip codes, or Telegram location pins. No API keys needed.

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Give the agent its own dedicated email inbox via AgentMail. Send, receive, and manage email autonomously using agent-owned email addresses (e.g. hermes-agent@agentmail.to).

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Complete security architecture overhaul for claude-flow v3. Addresses critical CVEs (CVE-1, CVE-2, CVE-3) and implements secure-by-default patterns. Use for security-first v3 implementation.

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Anchor your identity on the Autonomys Network so you can always be found — and always come back. Works with agents powered by Claude, GPT, Gemini, and Your agent always comes back. Anchor identity and memory on-chain so any new instance can resurrect from just an address — no local state, no single point of failure. Permanent identity and recovery on the Autonomys Network.

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Azure DevOps pull requests, for repos whose git remote is on dev.azure.com or *.visualstudio.com. Covers comment threads, which `az repos pr` cannot read or post. Use to create a PR for the current branch, check out, list or complete PRs, post code comments on a PR, reply to threads, and assess whether review feedback was addressed. Trigger on "create PR", "checkout PR 123", "list PRs", "complete PR", "comment on the PR", "post these review findings", "check PR feedback", "/dev-azdo:pr".

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Import existing Azure resources into Terraform using Azure CLI discovery and Azure Verified Modules (AVM). Use when asked to reverse-engineer live Azure infrastructure, generate Infrastructure as Code from existing subscriptions/resource groups/resource IDs, map dependencies, derive exact import addresses from downloaded module source, prevent configuration drift, and produce AVM-based Terraform files ready for validation and planning across any Azure resource type.

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.NET timezone handling guidance for C# applications. Use when working with TimeZoneInfo, DateTimeOffset, NodaTime, UTC conversion, daylight saving time, scheduling across timezones, cross-platform Windows/IANA timezone IDs, or when a .NET user needs the timezone for a city, address, region, or country and copy-paste-ready C# code.

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Give the agent its own dedicated email inbox via AgentMail. Send, receive, and manage email autonomously using agent-owned email addresses (e.g. hermes-agent@agentmail.to).

日本語の概要は準備中です。原文の説明を表示しています。

This skill covers detecting sophisticated cyber-physical attacks that follow the Stuxnet attack pattern of modifying PLC logic while spoofing sensor readings to hide the manipulation from operators. It addresses PLC logic integrity monitoring, physics-based process anomaly detection, engineering workstation compromise indicators, USB-borne attack vectors, and multi-stage attack chain detection spanning IT-to-OT lateral movement through to process manipulation.

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This skill covers detecting anomalies in Modbus/TCP and Modbus RTU communications in industrial control systems. It addresses function code monitoring, register range validation, timing analysis, unauthorized client detection, and deep packet inspection for malformed Modbus frames. The skill leverages Zeek with Modbus protocol analyzers, Suricata IDS with OT rules, and custom Python-based detection using Markov chain models for normal Modbus transaction sequences.

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Configures Fail2ban with custom filters and actions to detect port scanning activity, SSH brute force attempts, and network reconnaissance, automatically banning offending IP addresses and alerting security teams to suspicious network probing.

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This skill covers deploying anomaly detection systems for industrial control environments using machine learning models trained on OT network baselines, physics-based process models, and behavioral analysis of industrial protocol communications. It addresses building normal behavior profiles for SCADA polling patterns, detecting deviations in Modbus/DNP3/OPC UA traffic, identifying rogue devices, and correlating network anomalies with physical process data from historians.

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Analyzes indicators of compromise (IOCs) including IP addresses, domains, file hashes, URLs, and email artifacts to determine maliciousness confidence, campaign attribution, and blocking priority. Use when triaging IOCs from phishing emails, security alerts, or external threat feeds; enriching raw IOCs with multi-source intelligence; or making block/monitor/whitelist decisions. Activates for requests involving VirusTotal, AbuseIPDB, MalwareBazaar, MISP, or IOC enrichment pipelines.

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Detect and analyze heap spray attacks in memory dumps using Volatility3 plugins to identify NOP sled patterns, shellcode landing zones, and suspicious large allocations in process virtual address space.

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Detect abnormal access patterns in AWS S3, GCS, and Azure Blob Storage by analyzing CloudTrail Data Events, GCS audit logs, and Azure Storage Analytics. Identifies after-hours bulk downloads, access from new IP addresses, unusual API calls (GetObject spikes), and potential data exfiltration using statistical baselines and time-series anomaly detection.

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Optimize AEM Edge Delivery Services commerce product pages for search engine crawling and indexing. Audits client-side rendered product content for crawlability, validates meta tags, Product schema.org structured data, canonical URLs, and image optimization. Addresses the core challenge that EDS product pages render catalog data via JavaScript, which search crawlers may not fully execute. Use when product pages are not appearing in search results or have poor search visibility.

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Advanced API exploitation methodology focused on business logic abuse and sophisticated attack patterns that bypass traditional security controls. Covers business logic bypass through API call chaining and workflow manipulation. Addresses GraphQL-specific attacks including batching for credential brute-force, query depth exploitation, and introspection abuse. Includes pagination exploitation for data exfiltration, webhook hijacking for SSRF and data interception, and resource exhaustion through algorithmic complexity attacks. Covers race conditions in API transactions using parallel request techniques. Provides comprehensive JWT manipulation including algorithm confusion, kid injection, jku/x5u abuse, and claim tampering. Details API key leakage detection across source repositories, client-side code, and error messages. Covers undocumented endpoint discovery through predictable naming, debug routes, and source map analysis. Tooling includes Arjun, ParamSpider, jwt_tool, and GraphQL Voyager. Designed for a...

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Comprehensive offensive methodology for software supply chain attacks covering the full kill chain from reconnaissance through exploitation. Addresses dependency confusion across npm, PyPI, and NuGet ecosystems where internal registry override allows an attacker to inject malicious packages that shadow private dependencies. Covers typosquatting techniques for popular packages, compromised package injection via maintainer account takeover or social engineering, and build system attacks through Makefile injection, setup.py install hooks, and npm postinstall scripts. Extends into CI/CD artifact tampering where build outputs are replaced or modified in transit, code signing abuse through stolen or self-signed certificates, upstream repository compromise via commit injection or force-push to trusted repos, and container image supply chain attacks including base image trojaning and registry confusion. Maps to MITRE ATT&CK T1195.001 (Supply Chain Compromise: Compromise Software Dependencies and Development Tools...

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Deep-dive offensive methodology for dependency confusion and namespace attacks across all major package ecosystems. Covers npm scope confusion exploiting the gap between public and private scoped packages and .npmrc misconfigurations where registry mappings fail to pin internal scopes exclusively. Addresses PyPI namespace attacks through --extra-index-url resolution ordering, NuGet feed priority exploitation when multiple package sources are configured without clear directives, Maven and Gradle repository ordering where artifact resolution traverses repositories sequentially, Go module proxy abuse through GOPROXY misconfiguration, Ruby gems namespace squatting, and Docker image tag confusion with unqualified image references. Provides complete proof-of-concept methodology using safe callbacks including DNS canary via interactsh or Burp Collaborator and HTTP beacon with no destructive payload. Covers reconnaissance techniques for discovering internal package names through GitHub repository analysis, error ...

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Comprehensive methodology for auditing and exploiting TLS/SSL implementations and misconfigurations across network services and mobile applications. Covers protocol downgrade attacks including POODLE (CVE-2014-3566) against SSLv3 CBC padding, DROWN (CVE-2016-0800) cross-protocol attack leveraging SSLv2 export ciphers to decrypt TLS sessions, and FREAK (CVE-2015-0204) forcing RSA export-grade key exchange. Addresses BEAST (CVE-2011-3389) exploiting CBC IV predictability in TLS 1.0, CRIME (CVE-2012-4929) and BREACH targeting TLS-level and HTTP-level compression oracles respectively, and Heartbleed (CVE-2014-0160) for OpenSSL memory disclosure. Covers certificate validation bypass techniques for applications with improper hostname verification or chain validation, certificate pinning bypass using Frida and Objection for mobile application interception, HSTS bypass via NTP manipulation and subdomain exploitation, TLS 1.3 0-RTT replay attacks against non-idempotent endpoints, mutual TLS (mTLS) authentication a...

日本語の概要は準備中です。原文の説明を表示しています。