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概要と使いどころ

Detects aberrant splicing in single rare-disease patients vs a control panel using FRASER 2.0 (Bioconductor; Beta-binomial autoencoder on Intron Jaccard Index, default delta cutoff 0.1, q hyperparameter), OUTRIDER (gene-level outlier expression via autoencoder denoising), LeafcutterMD (Dirichlet-multinomial outlier mode of LeafCutter for annotation-free junctions), and DROP (Snakemake pipeline integrating FRASER2 + OUTRIDER + monoallelic expression for clinical diagnostics). The statistical model is fundamentally different from differential splicing — single-sample-vs-cohort outlier detection rather than two-group comparison. Standard tool in EU rare-disease (Solve-RD) and NIH UDN programs. Use when applying RNA-seq to undiagnosed Mendelian disease, validating predicted splice variants in clinical samples, or detecting cryptic splicing in disease tissue.

日本語の概要は準備中です。原文の説明を表示しています。

GPTomics/bioSkills1,2192026年8月15日 更新

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

GPTomics/bioSkills1,2192026年8月15日 更新

Use when working with iOS/macOS Keychain Services (SecItem queries, kSecClass, OSStatus errors), biometric authentication (LAContext, Face ID, Touch ID), CryptoKit (AES-GCM, ChaChaPoly, ECDSA, ECDH, HPKE, ML-KEM), Secure Enclave, secure credential storage (OAuth tokens, API keys), certificate pinning (SecTrust, SPKI), keychain sharing across apps/extensions, migrating secrets from UserDefaults or plists, or OWASP MASVS/MASTG mobile compliance on Apple platforms.

日本語の概要は準備中です。原文の説明を表示しています。

dpearson2699/swift-ios-skills1,1952026年8月1日 更新

Apply Swift API Design Guidelines to name, label, and document Swift APIs. Covers argument label rules (prepositional phrase rule, grammatical phrase rule, first-label omission), mutating/nonmutating pair naming (-ed/-ing participle pattern, form- prefix, sort/sorted, formUnion/union), side-effect naming (noun for pure, verb for mutating), documentation comment structure (summary by declaration kind, O(1) complexity rule), clarity at call site, role-based naming, protocol naming (-able/-ible/-ing), default arguments over method families, casing conventions, and terminology. Use when designing new Swift APIs, reviewing naming and argument labels, writing documentation comments, or refactoring for call site clarity.

日本語の概要は準備中です。原文の説明を表示しています。

dpearson2699/swift-ios-skills1,1952026年8月1日 更新

Implement Swift Codable models for JSON and property-list encoding and decoding with JSONDecoder, JSONEncoder, CodingKeys, and custom init(from:) or encode(to:). Use when parsing API responses, remapping keys, flattening nested JSON, handling date or data decoding strategies, decoding heterogeneous arrays, or integrating Codable with URLSession, SwiftData, or UserDefaults.

日本語の概要は準備中です。原文の説明を表示しています。

dpearson2699/swift-ios-skills1,1952026年8月1日 更新

Resolve Swift concurrency compiler errors, adopt approachable concurrency (SE-0466), and write data-race-safe async code. Use when fixing Sendable conformance errors, actor isolation warnings, or strict concurrency diagnostics; when adopting default MainActor isolation, @concurrent, nonisolated(nonsending), or Task.immediate; when designing actor-based architectures, structured concurrency with TaskGroup, or background work offloading; or when migrating from @preconcurrency to full Swift 6 strict concurrency.

日本語の概要は準備中です。原文の説明を表示しています。

dpearson2699/swift-ios-skills1,1952026年8月1日 更新

Implements keyboard, directional, and scene-level focus behavior across SwiftUI and UIKit. Use when managing @FocusState, defaultFocus, focused values, focusable interactions, focus sections, tvOS geometric focus and Siri Remote navigation, watchOS Digital Crown input, visionOS connected-device focus versus gaze hover/input targets, macOS key view loop and Full Keyboard Access, focus restoration after presentation changes, custom focus routing with UIFocusGuide, or debugging focus with UIFocusDebugger.

日本語の概要は準備中です。原文の説明を表示しています。

dpearson2699/swift-ios-skills1,1952026年8月1日 更新

Use when the user provides 1-50 concrete bad-case search queries for one Viking Search app and wants local deterministic fixes. This skill only verifies request-level fine-operation interventions against a read-only baseline scene and delivers a console-ready configuration sheet, validated payloads, and a replay script. It must not mutate scenes, apps, dictionaries, datasets, recall core parameters, or online defaults.

日本語の概要は準備中です。原文の説明を表示しています。

volcengine/SearchCLI1,1882026年10月14日 更新

setup

無料

This skill should be used when user encounters "ADC not found", "gcloud auth error", "GCloud MCP error", "Application Default Credentials", "project not set", or needs help configuring GCloud integration.

日本語の概要は準備中です。原文の説明を表示しています。

fcakyon/claude-codex-settings1,1762026年10月13日 更新

Runs LiveKit agent simulations and acts on the results. Use when the user says "run my simulations", "regression test my agent before deploying", "run the scenarios", "use lk agent simulate", "did my agent pass", "why did this scenario fail", "run simulations in CI", "test the audio pipeline", "check turn-taking and interruptions", or wants to check whole-conversation behavior before shipping. Covers text and audio mode and what each catches, running against a local or deployed agent, degraded-audio flags, automating a pre-release run, and triaging failures with list, view and export. For writing the scenarios use writing-livekit-scenarios. Not the default for a bare "test my agent", which goes to debugging-livekit-agents. Use this skill when the user names simulations, scenarios, a run, CI, or shipping.

日本語の概要は準備中です。原文の説明を表示しています。

fcakyon/claude-codex-settings1,1762026年10月13日 更新

Drives a multi-turn conversation with a LiveKit agent running locally to see what it does. Use when the user says "test my agent", "try my agent", "does this work", "why did it call that tool", "it says the wrong thing when I ask X", "test this change", or whenever you have edited an agent and need to check how it behaves. Wraps `lk agent debugger`: start the agent in text mode, send turns, read the tool calls, handoffs, errors and logs behind each reply, and restart after an edit. It runs without audio or a LiveKit room at one LLM call per turn, so it is the preferred way for a coding agent to live-test during development, and the default when the user says "test" without naming unit tests or simulations.

日本語の概要は準備中です。原文の説明を表示しています。

fcakyon/claude-codex-settings1,1762026年10月13日 更新

Guidance for distinctive, intentional visual design when building new UI or reshaping an existing one. Helps with aesthetic direction, typography, and making choices that don't read as templated defaults.

日本語の概要は準備中です。原文の説明を表示しています。

fcakyon/claude-codex-settings1,1762026年10月13日 更新

Reference for MATLAB audiostreamer (Audio Toolbox R2025a+). Without this skill, agents consistently default to legacy audioDeviceWriter/audioDeviceReader or base MATLAB sound(), producing less capable code. Use when writing code for audio playback, recording, full-duplex device I/O, real-time audio measurements, or audio I/O processing with callbacks. Also use when debugging audiostreamer errors, dropouts, or latency issues, or migrating from audioDeviceReader, audioDeviceWriter, audioPlayerRecorder, or audioplayer/audiorecorder.

日本語の概要は準備中です。原文の説明を表示しています。

matlab/matlab-agentic-toolkit1,1662026年10月9日 更新

Read BEFORE writing any code that builds or simulates OFDM systems. The default MATLAB patterns for OFDM (e.g., direct ifft/fft, awgn with 0 dBW power, missing symOffset) produce subtly incorrect results — always use ofdmmod/ofdmdemod instead of direct IFFT/FFT. This skill specifies the correct calling conventions for ofdmmod, ofdmdemod, ofdmChannelResponse, ofdmEqualize, and critical anti-patterns that must be avoided. Use when building OFDM transmitters or receivers, allocating subcarriers and guard bands, inserting pilots, computing SNR for OFDM, configuring fading channels (Rayleigh/Rician), estimating and equalizing channels, implementing timing and frequency synchronization, adding LDPC coding, designing resource grids, or setting up OFDM link simulations.

日本語の概要は準備中です。原文の説明を表示しています。

matlab/matlab-agentic-toolkit1,1662026年10月9日 更新

Read BEFORE writing any code that adds Additive White Gaussian Noise (AWGN) to signals and converts between SNR, Eb/No, Es/No, and per-subcarrier SNR for communications simulations, using awgn(), convertSNR(), berawgn(). The default MATLAB patterns for AWGN (e.g., 'measured' option, manual SNR formulas) produce subtly incorrect results. This skill specifies the correct calling conventions, required function usage, and critical anti-patterns that must be avoided.

日本語の概要は準備中です。原文の説明を表示しています。

matlab/matlab-agentic-toolkit1,1662026年10月9日 更新

Use when writing MATLAB functions with arguments blocks — repeating arguments (arguments (Repeating)), .?ClassName property import in constructors, name-value forwarding with namedargs2cell, or migrating from inputParser or validateattributes. Also when reviewing signatures for implicit-conversion pitfalls (size reshaping, class coercion, computed defaults), or when restricting, constraining, or validating function inputs — scalar vs vector enforcement, type rejection, size checking. Also when asked to harden inputs, make a function more robust, tighten input checking, or rewrite for safer input acceptance — even without "validation" or "arguments block" wording. Triggers on: arguments block, mustBe validators, name-value arguments, varargin, inputParser, nargin/narginchk, restrict input, type checking, scalar constraint, harden inputs, defensive programming. Not for: App Designer callbacks, Simulink mask parameters, class inheritance, or runtime validation outside function or property declarations.

日本語の概要は準備中です。原文の説明を表示しています。

matlab/matlab-agentic-toolkit1,1662026年10月9日 更新

Generate or improve MATLAB help text (documentation comments) for a function, class, or script file following MathWorks standards (H1 line, syntax paragraphs, See Also, 75-char lines). Read BEFORE writing MATLAB help — default patterns (Inputs:/Outputs: lists, block comments, uppercase See Also) produce non-conforming output. Use when writing, rewriting, fixing, or reviewing MATLAB help comments or function documentation.

日本語の概要は準備中です。原文の説明を表示しています。

matlab/matlab-agentic-toolkit1,1662026年10月9日 更新

Use when auditing repository documentation for drift, stale statements, broken references, or README mismatches, especially across published docs under `doc/` and key entry surfaces such as `README.md` (English default), `README.zh-CN.md`, `mcp/README.md`, and `mcp/README.zh-CN.md` during periodic maintenance or before preparing corrective PRs.

日本語の概要は準備中です。原文の説明を表示しています。

TencentCloudBase/CloudBase-AI-Toolkit1,1362026年10月14日 更新

Use this skill when a browser/Web app (React, Vue, Next, Nuxt, static sites, SPAs, dashboards, AI chat UI, 页面, 前端, 网页) needs AI models via @cloudbase/js-sdk. Default routing for Web/frontend AI — call directly from the browser, do NOT propose a Node.js proxy. Covers generateText and streamText; models via ai.createModel with groups cloudbase, hunyuan-exp, or custom-*, model id in the `model` field. MUST run two-step preflight before code — see body. NOT for Node.js backend (use ai-model-nodejs), Mini Program (use ai-model-wechat), or image generation (Node SDK only).

日本語の概要は準備中です。原文の説明を表示しています。

TencentCloudBase/CloudBase-AI-Toolkit1,1362026年10月14日 更新

Fast path for a minimal CloudBase Web + database demo (最小前后端 / 最小可用 fullstack / Lovable-like BaaS). Defaults to @cloudbase/js-sdk client CRUD (NoSQL app.database / PG app.rdb), MCP-only schema, preview-first, and forbids cloud functions unless secrets, cron/background jobs, or logic that security rules/RLS cannot express. Use for 搭一套 demo、留言板、Todo、Notes、Kanban, or when users say 带云函数+云数据库 but only need CRUD. NOT for production multi-service backends, CloudRun, WeChat Mini Programs, or tasks that truly need server secrets.

日本語の概要は準備中です。原文の説明を表示しています。

TencentCloudBase/CloudBase-AI-Toolkit1,1362026年10月14日 更新

CloudBase CLI (tcb, 云开发CLI, Tencent CloudBase命令行) resource management skill. Use when deploying cloud functions, CloudRun, storage, NoSQL/MySQL, static hosting, permissions, CORS/domains via tcb; for CI/CD and batch ops; when the user prefers CLI; or as the first-session fallback when CloudBase MCP tools are not loaded yet (after install/config, before IDE restart). Covers tcb login (device code for Tencent Cloud accounts; --cloudbase-api-key -e for environment API Key without an account; --apiKeyId/--apiKey for CI) and domain commands (fn/hosting/cloudrun/…) as MCP auth/manage parity — do not default to tcb deploy.

日本語の概要は準備中です。原文の説明を表示しています。

TencentCloudBase/CloudBase-AI-Toolkit1,1362026年10月14日 更新

Dub a video into another language and generate subtitles using the default Together + Cartesia stack. Trigger when the user wants to translate / dub / voice-over a video file, or generate subtitles for it. Handles `.mp4` / `.mkv` / `.webm`. Installs as the `violin` CLI (and `violin-api` for the FastAPI server) via `uv tool install`. For alternative models (OpenAI / ElevenLabs) or custom configs, point the user to the repo: https://github.com/shang-zhu/violin.

日本語の概要は準備中です。原文の説明を表示しています。

shang-zhu/violin1,0772026年9月4日 更新

Audit and generate in-app user guidance — onboarding flows, empty states, tooltips, feature tours, contextual help, defaults, and inline hints. Browses the app to find where new users would get stuck, then produces the actual content and code to fix it. Pairs with ux-audit: audit finds problems, this skill builds the solutions. Triggers: 'onboarding', 'help content', 'empty states', 'user guidance', 'first run experience', 'feature tour', 'app is confusing', 'new user experience', 'make the app welcoming'.

日本語の概要は準備中です。原文の説明を表示しています。

jezweb/claude-skills1,0622026年10月9日 更新

Generate custom favicons from logos, text, or brand colours. Produces favicon.svg, favicon.ico, apple-touch-icon.png, icon-192/512.png, and web manifest. Use whenever the user wants a favicon, mentions replacing a CMS default favicon, converting a logo into a favicon, creating branded initials icons, or troubleshooting favicon not displaying / iOS black square / missing manifest.

日本語の概要は準備中です。原文の説明を表示しています。

jezweb/claude-skills1,0622026年10月9日 更新