「iot」の検索結果

Otimiza atenção em transformers com Flash Attention para ganho de 2-4x em velocidade e redução de 10-20x em memória. Use ao treinar/executar transformers com sequências longas (>512 tokens), ao encontrar problemas de memória GPU com atenção, ou quando precisa de inferência mais rápida. Suporta SDPA nativo do PyTorch, biblioteca flash-attn, H100 FP8 e sliding window attention.

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Ajuste fino com eficiência de parâmetros para LLMs usando LoRA, QLoRA e 25+ métodos. Use ao fazer fine-tuning de modelos grandes (7B-70B) com memória GPU limitada, quando precisa treinar <1% dos parâmetros com perda mínima de precisão, ou para serviços multi-adapter. Biblioteca oficial do HuggingFace integrada ao ecossistema transformers.

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Buscar automaticamente documentação atualizada de bibliotecas/frameworks para Claude Code via API Context7

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Integracao completa com Amazon Alexa para criar skills de voz inteligentes, transformar Alexa em assistente com Claude como cerebro (projeto Auri) e integrar com AWS ecosystem (Lambda, DynamoDB, Polly, Transcribe, Lex, Smart Home).

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Knowledge base from the NIST Framework for Cyber-Physical Systems (SP 1500-201/202/203, v1.0, 2017). Use for engineering and analyzing cyber-physical systems (CPS) and IoT: the CPS Framework's aspect × facet grid (nine aspects of concern examined through conceptualization, realization, and assurance facets), cross-property trustworthiness risk management (safety/security/privacy/reliability/resilience together), data interoperability (syntactical/semantic/contextual, canonical models, identifiers, provenance), the timing aspect (time-interval classes, time domains, time-aware networking) and secure/resilient time (GNSS jamming/spoofing, PTP/NTP attacks, holdover, the clock-error model and Allan/MTIE metrics), plus the use-case requirements method. Bridges IT and OT under a clock. Scope limits: a 2017 living/draft document, thin on post-2017 standards and on detailed control catalogs; it names but does not reproduce ISO/IEC/IEEE 42010 and 15288 process text or permission-licensed third-party figures.

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Canalización automatizada de desarrollo de software. Escanea proyectos, prioriza tareas, analiza código u orquesta bucles de desarrollo. Cero dependencias (solo la biblioteca estándar de Python).

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Sistema de plugins genérico para aplicaciones Python. Detección automática, validación y tolerancia a fallos. Sin dependencias (solo biblioteca estándar de Python).

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Build event streaming applications using Azure Event Hubs SDK for JavaScript (@azure/event-hubs). Use when implementing high-throughput event ingestion, real-time analytics, IoT telemetry, or event...

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Use when working with Balena — balena IoT fleet management including applications, devices, releases, services, environment variables, and device diagnostics. Covers fleet deployment status, device connectivity, container health, update progress, and resource utilization across edge devices.

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This skill should be used when the user asks to "search for exposed devices on the internet," "perform Shodan reconnaissance," "find vulnerable services using Shodan," "scan IP ranges with Shodan," or "discover IoT devices and open ports." It provides comprehensive guidance for using Shodan's search engine, CLI, and API for penetration testing reconnaissance.

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This skill should be used when the user asks to "identify web application vulnerabilities", "explain common security flaws", "understand vulnerability categories", "learn about injection attacks", "review access control weaknesses", "analyze API security issues", "assess security misconfigurations", "understand client-side vulnerabilities", "examine mobile and IoT security flaws", or "reference the OWASP-aligned vulnerability taxonomy". Use this skill to provide comprehensive vulnerability definitions, root causes, impacts, and mitigation strategies across all major web security categories.

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Integracao completa com Amazon Alexa para criar skills de voz inteligentes, transformar Alexa em assistente com Claude como cerebro (projeto Auri) e integrar com AWS ecosystem (Lambda, DynamoDB, Polly, Transcribe, Lex, Smart Home).

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Drug and chemical toxicity assessment via adverse outcome pathways (AOPs), real-world FAERS adverse event signals, FDA labels, and toxicogenomic associations. Triangulates molecular initiating event to cellular outcome to organ-level toxicity to clinical adverse event. Use for hepatotoxicity/cardiotoxicity/nephrotoxicity prediction and toxicology reports.

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Analyzes species-environment relationships with constrained ordination (CCA, RDA, db-RDA), variance partitioning, indicator species (indicspecies IndVal.g group-equalized), PERMANOVA paired MANDATORILY with PERMDISP (Anderson & Walsh 2013; dispersion confounds centroid tests), Joint Species Distribution Models (HMSC, sjSDM, gjam) with explicit rejection of "residual covariance equals biotic interaction", phylogenetic community ecology (SES_MPD/MNTD), trait-environment via RLQ + fourth-corner with corrected modeltype=6 (Dray 2014), bipartite network metrics (NODF, modularity) with curveball null (Strona 2014), and Mantel-test replacements (dbRDA, GDM) for spatial data. Use when testing how environmental gradients structure communities, identifying habitat indicator taxa, partitioning variance among predictors, deciding whether PERMANOVA significance is location vs dispersion, picking among HMSC/sjSDM/gjam, or replacing Mantel tests for landscape data.

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Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version pinning, the cDNA-vs-DRS chemistry distinction (cDNA-Nanopore CANNOT be used for modification detection), and orthogonal validation against MeRIP / GLORI. Use when calling m6A from ONT DRS without immunoprecipitation, choosing m6Anet vs xPore vs Nanocompore vs ELIGOS vs Dorado native, interpreting per-site `probability_modified` vs `mod_ratio` vs per-read modification probabilities, comparing methylation between conditions from ONT data, deciding between m6Anet for known DRACH sites and Dorado/Remora for genome-wide screening, pinning RNA002 vs RNA004 chemistry and basecaller model versions, or troubleshooting eventalign / dataprep failures.

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Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

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Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers. Covers bottleneck math (250x cells/sgRNA requires ~25M cells implanted; impossible for most syngeneic models, forcing focused libraries), focused library design (Manguso 2017 Nature 547:413 immune screen; Chen 2015 tumor screens), CRISPR-StAR intrinsic-control screening (Uijttewaal 2025 Nat Biotechnol 43:1848), clonal-dynamics-limited detection, tumor-explant DNA recovery, syngeneic vs xenograft vs PDX considerations, and the relationship to downstream MAGeCK / drugZ analysis. Use when designing in vivo CRISPR screens for tumor / immune / metastasis biology, choosing focused vs genome-wide for animal models, addressing bottleneck-induced clonal collapse, picking the syngeneic / xenograft / PDX model, integrating in vivo with in vitro results, or applying CRISPR-StAR for animal experiments.

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Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

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Queries myvariant.info BioThings aggregator for ClinVar, gnomAD, dbSNP, dbNSFP, COSMIC, CADD, and CIViC annotations in batched, version-tracked requests. Use when annotating variant lists from multiple databases simultaneously without managing per-source APIs, and when reproducibility-grade analyses require recording source data versions via _meta.

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Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, and applies the Patel et al 2024 *Nat Biotechnol* review's failure-mode framework to validate that normalization is correctly applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.

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Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.

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Integracao completa com Amazon Alexa para criar skills de voz inteligentes, transformar Alexa em assistente com Claude como cerebro (projeto Auri) e integrar com AWS ecosystem (Lambda, DynamoDB, Polly, Transcribe, Lex, Smart Home).

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Arquiva briefs, peças e aprendizados no Obsidian (pasta local) e no Notion (via MCP). Use quando o usuário disser "salvar no Obsidian", "arquivar", "registrar no Notion", "biblioteca de peças", "documentar a campanha", "onde ficou aquela peça". Obsidian é filesystem direto — não precisa de MCP.

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Mantém coerência visual entre peças geradas por IA — seed, modelo fixo, referência de estilo e biblioteca de prompts da marca. Use quando o usuário disser "as peças não parecem da mesma campanha", "manter o estilo", "consistência", "cada imagem saiu diferente", "padronizar o visual gerado". É o problema mais difícil de geração por IA em escala.

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