「number」の検索結果

BOM (Bill of Materials) management for electronics projects — the workflow skill that coordinates DigiKey, Mouser, LCSC, element14, JLCPCB, PCBWay, and KiCad skills around a unified BOM lifecycle. Create, update, and maintain BOMs with part numbers, costs, quantities stored as KiCad symbol properties. ALWAYS trigger this skill for any task involving component sourcing, pricing, ordering, distributor searches, BOM export, or fabrication preparation — even if the user names a specific distributor or fab house (e.g. "search DigiKey for...", "generate JLCPCB BOM", "order from Mouser"). This skill analyzes the schematic for sourcing gaps, recommends which distributor/fab skills to call for each gap, and writes results back as symbol properties — the agent (or user) performs the actual searches via the called skills. Also trigger on phrases like "what parts do I need", "order components", "how much will this cost", "export for JLCPCB", "find parts for this board", "compare pricing", or "check stock".

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Search Newark, Farnell, and element14 for electronic components — find parts by MPN or distributor part number, check pricing/stock, download datasheets, analyze specifications. One unified API covers all three storefronts (Newark for US, Farnell for UK/EU, element14 for APAC). Free API key, simple query-parameter auth, no OAuth. Datasheets download directly from farnell.com CDN with no bot protection. Sync and maintain a local datasheets directory for a KiCad project, or use batch MPN-list seeding (`--mpn-list`) for bulk workflows without a project. Use this skill when the user mentions Newark, Farnell, element14, needs parts from a non-US distributor, wants to compare pricing across regions, or needs datasheets from a source that doesn't require complex API auth. For package cross-reference tables and BOM workflow, see the `bom` skill.

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Go and find the reels that are actually working right now in the user's niche, rank them by how far each beat its own account, name the hook formula each one used, and turn that into a swipe file they can shoot from. Use when the user says "find viral videos", "what's working right now", "what are people posting in my niche", "reverse engineer this account", "build me a swipe file", "why is this reel doing numbers", or asks what to make next and has no evidence to answer with.

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Mandatory pre-publish review gate for a UGC video render. Transcribes the finished render's AUDIO with Whisper and word-diffs it against the approved spoken script, then gates pinning the final render (video_project_upsert patch.final_render_id) — blocking a render whose generated audio mis-voices a word (e.g. the approved "human-vetted" spoken as "human witted"), says a different number or brand name, flips a negation, drops an approved phrase, or comes back silent. Correct speech written differently ("5mg" said "five milligrams", "30%" said "thirty percent", a spoken URL, "don't" said "do not", "braxleybands" said "braxley bands", a confirmed pronunciation like "AG1" said "A G one") passes. Runnable, gating counterpart to content-goose's review-transcript-integrity atom. Every ugc-video-formats recipe runs this after render and BEFORE pinning the final render.

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Find emails, phone numbers, and enrich profiles using ContactOut. LinkedIn enrichment, people search, company enrichment, and batch operations.

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Assemble a narrated motion-graphic LISTICLE video ad from a config — a spoken voiceover (cloned or cast, in the chosen tone) carries a numbered listicle while N web-animated hyperframe beats (HTML plus the Web Animations API, one branded design system of alternating tiles, big hero numerals, and callouts in the chosen visual style) are rendered frame-by-frame via Playwright and anchored to the VO's word-level timestamps, optional color-graded breather windows (brand clip, AI clip, or motion-graphic) give visual breath, and captions burn ONLY inside those B-roll windows (2-word chunks, ASS Format header carrying a Name field so none drop) with the VO mixed under a low music bed. This is the FREE deterministic assembly stage (Playwright beat render plus ffmpeg concat plus window-masked caption burn plus VO-and-music mix plus final composite) — the VO, the music bed, and any AI breather clips come from create-vo-elevenlabs, create-music-elevenlabs, and create-video-fal. Use for the vo-anchored-motion-listicle format.

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Answer questions about a brand's Meta ads (spend, results, which ad is winning, is it paused, why did Goose do that) only from reads made in the same turn, with the data window and sync time on every number and a plain caveat when the connection is stale or partial. Use it whenever a user asks how their ads are doing or why an ad action was taken.

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Render the logo-equation card ad (7s, 9:16) — partner icon + brand icon joined by a plus sign as an equation, a two-line "= outcome" headline, four numbered steps, and a CTA that hard-cuts in at 2s, on a static black card over timelapse b-roll, no voice. render_card.py draws the two card plates with measured geometry and hard guardrails (the user must confirm the integration is real, no partnership/endorsement/ranking words, no comment-bait CTA, no dashes); compose.py lays the card over the b-roll sped up to read as a timelapse, with an optional bed; measure_motion.py gates the b-roll (a real-time shot reads as a photo). Free, local.

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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

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Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.

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Rank and prioritize neoantigen/epitope candidates by likely T-cell response using NeoFox feature annotation, PRIME2.0, BigMHC-IM, the Łuksza/Balachandran fitness model (agretopicity + foreignness), and pVACtools tiering. Encodes the field's hard truths that immunogenicity is the least-solved layer (dedicated scores ~AUROC 0.6-0.7, modest PPV), that scores are valid only for RANKING within one patient (never absolute go/no-go or cross-patient), that DAI has anchor-inflation and WT-denominator traps, and that stacking weak correlated scores into one number is a red flag. Use when ordering a candidate list for a vaccine. Binding lives in mhc-binding-prediction; calling in neoantigen-prediction.

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Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.

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Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.

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Estimates time-scaled phylogenies, molecular-clock rates, effective reproduction number R_e, and population dynamics from dated pathogen genomes using TreeTime (maximum-likelihood) and BEAST2 (Bayesian; strict/relaxed clocks; coalescent, Bayesian-Skyline, Skygrid, Birth-Death-Skyline, and sampled-ancestor priors; structured coalescent via MASCOT). Covers root-to-tip clock QC via TempEst, date-randomisation tests, recombination masking via Gubbins/ClonalFrameML before clock inference for recombining bacteria, BDSKY origin-vs-rootHeight pitfalls, sampling-bias correction, multi-chain convergence diagnostics, and reconciling phylodynamic R_e with case-based R_t. Use when dating outbreak origins, estimating substitution rates, inferring R_e through time, building time-calibrated Nextstrain Augur trees, choosing between strict and relaxed clocks, fitting Birth-Death-Skyline models, diagnosing temporal-signal failure, running MASCOT for structured-population analyses, or using UShER for pandemic-scale placement.

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Identifies non-coding RNAs (tRNA, rRNA, snoRNA, snRNA, riboswitches, sRNAs) using Infernal covariance-model search against Rfam, tRNAscan-SE 2.0 for tRNA, barrnap for rRNA, and ARAGORN for tmRNA, plus the small-RNA-seq boundary for miRNA and the transcript-assembly boundary for lncRNA. Covers the structure-conserved-not-sequence-conserved principle (why BLAST fails), GA-threshold and clan-competition correctness, tRNAscan-SE domain modes and pseudogene flags, rDNA copy-number collapse, and why homology annotation is a recall floor. Use when performing genome-wide ncRNA annotation, choosing the right tool for an RNA class, or interpreting ncRNA counts.

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Assigns GO terms, Pfam/InterPro domains, KEGG orthologs, EC numbers, and product names to predicted proteins using eggNOG-mapper (orthology), InterProScan (domain signatures), and KofamScan (KEGG), routing specialized functions to dbCAN/antiSMASH/AMRFinderPlus/SignalP. Covers the orthology-vs-domain-vs-homology paradigms, the annotation-error percolation cascade, domain-presence-is-not-function, GO IEA circularity in enrichment, evidence tiering, and bit-score/coverage thresholds. Use when adding functional annotation to predicted genes, choosing between eggNOG-mapper and InterProScan, or judging how much to trust a functional label.

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Calculates statistical power for high-dimensional genomics experiments (bulk RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, methylation, proteomics) under negative-binomial count models using RNASeqPower, PROPER, and simulation via powsimR, distinguishing per-gene from marginal (transcriptome-wide) power, the role of mean expression and dispersion, and the sequencing-depth-versus-replicate tradeoff. Covers simulation as the honest default for overdispersed counts, FDR-aware average power versus single-test power, observed/post-hoc power as an anti-pattern, and the winner's-curse / Type-S / Type-M consequences of underpowering. Use when planning replicate number for a sequencing experiment, deciding whether to add depth or samples, choosing closed-form versus simulation power, estimating power from pilot dispersions, or justifying replication in a grant. For clinical-trial power see clinical-biostatistics/power-and-sample-size; for the inverse sample-size question see experimental-design/sample-size.

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Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

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Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed dependence and metacluster stability, why embeddings are for looking not measuring, and median-heatmap annotation/merging. Use when discovering populations without predefined gates, choosing a clustering algorithm, selecting the number of metaclusters, or annotating clusters into cell types.

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Estimates the minimum biological replicates (or cells/events) for a target power at a target FDR in genomics experiments using ssizeRNA, PROPER, powsimR for scRNA-seq, and pilot-data dispersion estimation from DESeq2/edgeR. Covers the biological-versus-technical replication distinction (technical replicates do not add degrees of freedom for biological inference), replicate-number-versus-sequencing-depth budgeting, scRNA-seq sample-versus-cell allocation under a pseudobulk model, and the critique that "n=3" is a publication convention rather than a power calculation. Use when budgeting a sequencing experiment, writing the sample-size justification in a grant, estimating replicates from pilot data, allocating a fixed budget between samples and depth, or planning scRNA-seq cohort size. For clinical-trial sample size see clinical-biostatistics/power-and-sample-size; for the power-given-n direction see experimental-design/power-analysis.

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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.

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Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Formats and parses locale-aware numbers, decimals, currencies, percentages, dates, durations, measurements, names, lists, byte counts, and URLs with Foundation FormatStyle and ParseableFormatStyle. Use when replacing legacy Formatter subclasses, designing reusable format APIs, using SwiftUI Text(_:format:), correcting availability, or testing user-facing formatted output across locales.

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This skill should be used when the user asks for "ADHD output", "fewer output tokens", "short numbered steps", "limited working memory formatting", or explicitly invokes "adhd-output-style".

日本語の概要は準備中です。原文の説明を表示しています。