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Query myvariant.info API for aggregated variant annotations from multiple databases (ClinVar, gnomAD, dbSNP, COSMIC, etc.) in a single request. Use when annotating variants with clinical and population data from multiple sources simultaneously.

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Migrate workloads from Microsoft Azure to AWS. Triggers on: migrate from Azure, Azure to AWS, move off Azure, migrate AKS to EKS, migrate App Service or Azure VMs to AWS compute, migrate Azure SQL or Azure Database to RDS, migrate Cosmos DB to DynamoDB, migrate Azure OpenAI to Bedrock, move Azure AI or agentic workloads to AWS, estimate AWS costs for my Azure infrastructure, what-if workshop. Runs a 6-phase process: discover Azure resources from Terraform, the live `az` CLI, app code, and billing exports, then clarify, design, estimate costs, optionally reprice scenarios, generate artifacts, and collect feedback. Clarify gates Design, Estimate, and Generate; Generate is opt-in at the post-Estimate decision gate. Bicep/ARM discovery is not yet implemented; a Bicep/ARM-only workspace halts. Do not use for: GCP migrations (see gcp-to-aws), Heroku migrations (see heroku-to-aws), general AWS architecture advice (see architect-for-startups), AWS-to-Azure reverse migration, or Azure-to-Azure refactoring.

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Advises on Amazon RDS open-source engines (MySQL, MariaDB, PostgreSQL) for instance creation, upgrade planning, commitment pricing, proxy evaluation, and Blue/Green deployments. Handles any RDS MySQL, MariaDB, or PostgreSQL question, including create a production-ready RDS MySQL instance, provision an RDS PostgreSQL database, run the RDS upgrade advisor for my RDS MySQL instance, what are my upgrade options, upgrade RDS MariaDB from 10.6 to the latest version, should I buy reserved instances or a savings plan for db.r7g.2xlarge RDS MySQL, change a VARCHAR to INT column on RDS MySQL 8.0 with Blue/Green, and does RDS Proxy help when PgBouncer already runs in transaction mode. Covers instance creation with production best practices, describe-db-instances and describe-db-engine-versions upgrade-target workflow, live prechecks via SSM or direct connection, RI versus DSP commitment pricing, RDS Proxy versus PgBouncer, and Blue/Green lifecycle with binlog replay compatibility.

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Builds and deploys containerized workloads on Elastic Kubernetes Service (EKS), Elastic Container Service (ECS), Fargate, and ECR (Elastic Container Registry). Covers general EKS knowledge, Karpenter, AWS Load Balancer Controller and leveraging various open source Kubernetes projects with EKS. Covers general ECS knowledge, task definitions, Fargate services, ECS Exec, ECS Express Mode and ECS Managed Instances. Covers general Elastic Beanstalk knowledge, Elastic Beanstalk configuration and platforms supported by Elastic Beanstalk. Covers general ECR knowledge, ECR repository setup and lifecycle policies. Includes recommending, enabling, and reading Amazon ECS Action Logs to troubleshoot control-plane failures (deployment rollback/circuit-breaker, task placement, scaling, task replacement). Applies when deploying, debugging, or optimizing containers on AWS. Should be used instead of relying on internal knowledge for these services.

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REST API design with resource naming, pagination, versioning, and OpenAPI spec generation

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Create a current, source-linked weather briefing for a named city using the Open-Meteo geocoding and forecast APIs. Activate for requests such as "what is the weather in Sao Paulo?", "prepare a current weather briefing for Tokyo", or "get today's live conditions for New York". Do not use for travel booking, weather alerts, historical climatology, or safety-critical decisions.

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Migrate a whole ArcGIS Hub site into a PortalJS Arc portal end-to-end. Harvests the Hub /data.json (DCAT-US) inventory, exports every FeatureService layer through the ArcGIS REST query API with resultOffset paging, converts each to the serverless dual tier (PMTiles render + GeoParquet query) with tabular items to Parquet, pushes everything to Cloudflare R2 via Git LFS, appends dual-tier datasets.json entries, and writes a source-vs-derived parity report. Use to move a City or sector ArcGIS Hub open-data portal onto PortalJS with no server-side compute.

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Cut one long podcast, interview, course, livestream, or other source video into social-ready shorts, reels, highlights, or clip timelines from existing project media. Use when the user asks to cut a long video into Shorts, Reels, TikToks, Xiaohongshu posts, best moments, highlights, or multiple clips.

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Turn one pool of existing project media into a batch of distinct, publishable montage cuts instead of a single hero edit. Use for batch montage, one-source-many-outputs, 一源多出, 批量混剪, 批量出片, 矩阵号, 多账号分发, variant batches, deduped cuts, 去重变体, 防搬运, or when the user asks for N different versions of the same footage.

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dstack is an open-source control plane for GPU provisioning and orchestration across GPU clouds, Kubernetes, and on-prem clusters.

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Covers what the organization owns and what it is only borrowing — trademarks and clearance, copyright and work-for-hire, patents and trade secrets, open-source license obligations and copyleft reach, and IP terms in customer, contractor and AI-tool agreements. Use this to check whether a name is usable, establish that you own work you paid for, decide how to handle a license obligation in a dependency, or respond to an infringement claim.

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This skill is applicable when using LaminDB. LaminDB is an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR-compliant. It is suitable for managing biological datasets (scRNA-seq, spatial transcriptomics, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakes, or ensuring data lineage and reproducibility in biological research. It covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integration with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.

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Draft and submit evidence-backed XQUIC GitHub bug issues in the repository's CONTRIBUTING and issue-template format. Use when preparing or opening an alibaba/xquic issue that must identify an exact RFC or draft mechanism, expected-versus-actual behavior, reproduction evidence, and optional verified source root cause; requires issue-check to return true before any GitHub submission.

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Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and pivot tables. When Claude needs to work with spreadsheets (.xlsx files) for: (1) Creating new spreadsheets with data and formatting, (2) Reading or analyzing Excel data with pandas, (3) Creating pivot tables programmatically with openpyxl, (4) Building multi-sheet workbooks with source data and pivot table sheets, or (5) Any Excel file operations

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Use for formulating, solving, debugging, and validating mixed-integer linear optimization models with open-source solvers, including variable indexing, sparse constraints, linearized costs, solver limits, MIP gaps, incumbent extraction, numerical tolerances, and deterministic output reporting.

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Use when the user asks to review, verify, or audit a report, manuscript, or analysis in the workspace for traceability — resolving citations, flagging numbers with no source, and checking figures against the code that generated them. Emits a structured review block the app renders as reviewer findings. Verifies traceability, never "correctness".

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Für Non Solicitation: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Tatbestands- oder Anspruchsmatrix.

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Use when converting, repairing, or packaging an existing local or external agent/team into Agentlas architecture for local install, Agentlas import, Codex plugin use, Claude adapter use, or open-source release.

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Use when packaging this meta-agent for public Codex plugin registration, Claude Code installation, GitHub release, one-line terminal install, or open-source distribution.

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Debug live Azure Kubernetes Service (AKS) incidents with a read-only, evidence-first investigation. WHEN: pod crashes or Pending, CrashLoopBackOff, OOMKilled, ImagePullBackOff, node NotReady, DNS or ingress failure, connectivity timeout, network policy, SNAT exhaustion, node-pool scaling blocked by QuotaExceeded or InsufficientVCPUQuota, upgrade stuck, spot or zone disruption, a bare VMExtensionProvisioningError or AllocationFailed wrapper, an uncataloged capacity symptom, or 'investigate my AKS cluster'. DO NOT USE FOR: packet capture (use aks-network-capture); GPU or model-serving issues (use aks-gpu-inference); cluster creation or provisioning (use azure-kubernetes); cost (use cost-analysis from the optional azure-cost plugin); pod rightsizing (use azure-kubernetes); a fully qualified documented AKS signature with every required nested qualifier (use aks-known-issues); standalone failures on non-AKS Azure resources (use azure-diagnostics). Unqualified errors and open-ended incidents stay here only for AKS.

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Write a CONTRIBUTING guide that helps people contribute to an open-source project without friction. Use when asked to write a CONTRIBUTING.md, set up contribution guidelines, or make a repo welcoming to contributors. Produces a clear guide: how to set up, the contribution workflow, standards, PR expectations, and how to get help — lowering the barrier to a first PR.

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Set up the essentials in the right order after moving to a new country — the ID/registration, bank account, phone, address, and social/tax number that unlock each other — so you don't get stuck in the chicken-and-egg loops that trap newcomers. Use when someone says 'I just moved to a new country', 'what do I do first after arriving', 'set up my life in [country]', or 'I can't open a bank account without an address but can't rent without a bank'. Produces a sequenced arrival checklist with dependencies and the official offices for each. Routes to official sources; rules are local.

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Source authentic, high-res PUBLIC-DOMAIN artwork from museum open-access APIs (Met, Cleveland, SMK, Rijksmuseum, NGA, Art Institute of Chicago, Getty, Smithsonian) instead of AI-generated or generic-stock imagery. The default move whenever a visual needs an aesthetic, credible image (blog heroes, decks, social cards, essay/spec figures). Verified keyless recipes + licensing rules inside.

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Use when packaging code, models, datasets, or media as ACM MM (ACM Multimedia) artifacts — building the anonymous review package versus the public release, and choosing between the Open Source Software Competition, the Dataset track, the Reproducibility track, and main-track supplementary evidence, each with its own blinding and expectations.

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