「traction」の検索結果

Quick capture of raw thoughts with intelligent domain classification and competitive intelligence extraction

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Repurposes long-form video (podcasts, interviews, talks) into short-form vertical clips for Instagram Reels, TikTok, and YouTube Shorts. Handles transcription, moment selection, clip extraction, speaker-tracked reframing (16:9 to 9:16), and animated captions.

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AI-powered web search, crawling, extraction, and deep research

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Web scraping, crawling, and AI-powered answer extraction at scale

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Crawl a website's sitemap and blog index to build a complete content inventory. Lists every page with URL, title, publish date, content type, and topic cluster. Groups content by category and topic. Optionally deep-reads top N pages for quality analysis and funnel stage tagging. Use before SEO audits, content gap analysis, or brand voice extraction.

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Prepare for investor calls by pulling upcoming meetings from Google Calendar, deeply researching each investor and their firm (website scraping, portfolio analysis, thesis extraction), checking for competitor conflicts, and outputting an honest prep sheet with compatibility assessments. Use when asked to prep for investor meetings, fundraising calls, VC meetings, or demo day.

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Web scraping with structured data extraction - define your output schema

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Web search, AI answers, content extraction, and async deep research

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Competitor intelligence system. Research competitors across web, Reddit, Twitter/X, LinkedIn, and blogs. Build deep competitor profiles, monitor content and positioning changes, track what gets traction, and identify competitive gaps. Covers data collection, content tracking, and strategy analysis. Pure research skill — uses web search, web fetch, and optionally Apify for social scraping. No scripts required.

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Extract structured data matching a JSON schema from websites. Handles complex nested schemas, arrays, pagination, and validation. Always outputs via formatOutput.

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学习笔记自动化：视频/播客转录 → 知识点提取 → 闪卡生成 → 知识图谱更新。触发词：学习笔记、闪卡、Anki、知识提取、视频学习

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Patterns for building entity actors with Akka.Hosting - GenericChildPerEntityParent, message extractors, cluster sharding abstraction, akka-reminders, and ITimeProvider. Supports both local testing and clustered production modes.

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Choosing the right concurrency abstraction in .NET - from async/await for I/O to Channels for producer/consumer to Akka.NET for stateful entity management. Avoid locks and manual synchronization unless absolutely necessary.

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Critical Akka.NET best practices including EventStream vs DistributedPubSub, supervision strategies, error handling, Props vs DependencyResolver, work distribution patterns, and cluster/local mode abstractions for testability.

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Detects somatic mutations in circulating tumor DNA, treating low-VAF detection as a signal-versus-noise problem set by error suppression and molecules sampled, not by the choice of caller. Distinguishes de novo CALLING (scanning a panel for unknown variants, bounded by per-locus error and multiple testing) from tumor-informed DETECTION (tracking a pre-specified variant set, where panel integration reaches single-ppm). Covers VarDict and Mutect2 for de novo calling, UMI-aware callers, and a pysam-based known-variant VAF tracker, with matched-WBC subtraction as the mandatory defense against clonal hematopoiesis (the dominant false positive). Use when calling or tracking tumor mutations from plasma cfDNA, setting a VAF threshold, or deciding whether a low-VAF call is tumor versus CHIP.

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Detects cancer and infers tissue-of-origin from cfDNA methylation by choosing conversion chemistry (bisulfite vs EM-seq vs TAPS vs cfMeDIP), calling read-level methylation haplotypes rather than averaged beta values, and deconvolving a hematopoietic-dominated cfDNA mixture against a methylation atlas via NNLS/quadratic programming. Encodes the GRAIL/CCGA thesis that thousands of tissue-specific markers make methylation outperform sparse mutations for multi-cancer early detection (MCED) and localization, and that single concordantly-methylated fragments give ppm-level sensitivity. Uses MethylDackel for extraction (mbias-then-extract), MEDIPS/QSEA for enrichment data, scipy.optimize.nnls for deconvolution. Use when building an MCED or methylation-MRD assay, picking a conversion chemistry for low-input plasma, or deconvolving tissue-of-origin from cfDNA.

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Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Extracts and assigns COSMIC v3.4 mutational signatures (86 SBS / 11 DBS / 18 ID / 21 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.

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Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

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Enumerates virtual chemical libraries via reaction SMARTS transformations using RDKit and reaction templates, with explicit handling of atom mapping, RDChiral template extraction, product validation, RECAP/BRICS fragmentation, R-group decomposition, matched molecular pair analysis (MMPA), and Free-Wilson analysis. Use when generating combinatorial libraries from building blocks, enumerating analog series, deriving structure-activity rules, or extracting transformations from reaction data.

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This skill should be used when writing, reviewing, or refactoring Python code. Covers code integration, idiomatic patterns, docstring formatting, anti-abstraction rules, and software engineering basics.

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Use when tasks involve reading, creating, or reviewing PDF files where rendering and layout matter; prefer visual checks by rendering pages (Poppler) and use Python tools such as `reportlab`, `pdfplumber`, and `pypdf` for generation and extraction.

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Wilkinson, branchline, ratrace, directional couplers, corporate dividers, Rotman lenses for power splitting and beam-forming. TRIGGER: user asks to design, create, or analyze any coupler, splitter, power divider, combiner, or Rotman lens. Invoke BEFORE writing code — class names and design() availability vary per coupler type. SKIP: EM simulation/S-parameter extraction of an existing component (use matlab-analyze-em), building custom non-catalog geometry (use matlab-assemble-pcb-layout), material/stackup setup only (use matlab-manage-pcb-material), cascading multiple components (use matlab-integrate-pcb-circuit).

日本語の概要は準備中です。原文の説明を表示しています。