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A collection of tools for doing various analyses of single-cell RNA-seq gene expression data, with a focus on quality control and visualization.

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Provides basic utility functions for performing single-cell analyses, focusing on simple normalization, quality control and data transformations. Also provides some helper functions to assist development of other packages.

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This packages provides C++ header files for developers wishing to create R packages that processes BAM files. ompBAM automates file access, memory management, and handling of multiple threads 'behind the scenes', so developers can focus on creating domain-specific functionality. The included vignette contains detailed documentation of this API, including quick-start instructions to create a new ompBAM-based package, and step-by-step explanation of the functionality behind the example packaged in

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Statistical and computational method to analyze the co-expression of gene pairs at single cell level. It provides the foundation for single-cell gene interactome analysis. The basic idea is studying the zero UMI counts' distribution instead of focusing on positive counts; this is done with a generalized contingency tables framework. COTAN can effectively assess the correlated or anti-correlated expression of gene pairs. It provides a numerical index related to the correlation and an approximate

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This package encapsulate many functions to conduct a differential topology analysis. It focuses on analyzing an 'omic dataset with multiple conditions. While the package is mostly geared toward scRNASeq, it does not place any restriction on the actual input format.

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Ambient fleet-health check that surfaces anything worth attention (default), or an on-demand priority brief - the 3 things to focus on, why now, and what moved (var=brief)

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Amazon product listing image strategy and optimization. Comprehensive shot planning, infographic design, lifestyle photography, mobile optimization, and conversion-focused visual content. Use when the user asks about Amazon images, product photography, visual optimization, or listing conversion.

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Startup diagnostic router. Use FIRST when a founder doesn't know where to start, has multiple overlapping problems, or asks a vague question like 'what's wrong with my startup', 'why aren't people buying', 'what should I focus on', 'where do I even begin', 'nothing is working'. Routes to the right framework from the 15 available skills — or tells you when no framework fits and you just need to go talk to people. This is the entry point. Use it before reaching for any specific skill.

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Manage and compare multiple affiliate programs as a portfolio. Triggers on: "manage my affiliate programs", "compare my programs", "portfolio overview", "which program should I focus on", "diversify my affiliate income", "program switching", "affiliate portfolio", "program comparison", "revenue allocation", "which programs to drop", "add new programs", "affiliate program strategy".

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Scaffold your own focused AI agent harness — pick host (Claude Code, Codex, pi.dev, Hermes), template, agents, skills, and ship a npm-publishable harness with its own npx CLI. Use when a user asks to "create my own agent harness", "scaffold a harness", "make a custom Claude Code plugin like ruflo", or "build a vertical AI assistant for X".

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Use when working on accessibility, a11y, WCAG, ARIA, screen readers, keyboard nav, focus order, contrast, alt text, captions, reduced motion, or target sizes; not language/culture/device (see inclusive-design).

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Generate a Disaster Recovery plan with RTO/RPO targets. Use when someone asks to "create a DR plan", "disaster recovery", "business continuity", or "RTO RPO". Do NOT use for step-by-step restoration runbooks — use /pmstudio-recovery instead. Designed for SaaS platform products where Coco Inc is the customer — focuses on service continuity, data recovery, and vendor dependency management rather than infrastructure rebuild.

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Compose and Compose Multiplatform expert for UI development across Android, Desktop, iOS, and Web. Use whenever the user mentions Compose APIs (@Composable, remember, LaunchedEffect, NavHost, MaterialTheme, LazyColumn, Modifier, recomposition), Compose Multiplatform (commonMain, expect/actual, Res.*, ComposeUIViewController, UIKitView, ComposeViewport), Android TV (tv-material, D-pad, focus, Carousel), Material 3 motion, atomic design systems, design-to-code workflows, Paging 3, or navigation. Activates Review Mode on GitHub PR URLs and review phrases ("review this PR", "what's wrong with this"). Auto-detects Compose projects on session_start. Backed by actual androidx/androidx and JetBrains/compose-multiplatform-core source receipts. See "## When this skill applies" in SKILL.md for the full trigger surface.

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Apply test-driven development with small, behavior-focused feedback loops. Use when the user asks to build or fix something test-first, mentions red-green-refactor, or wants integration tests.

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Diagnose hard bugs and performance regressions with reproducible evidence, focused hypotheses, and proportional instrumentation. Use when something is broken, failing, throwing, intermittently wrong, or unexpectedly slow.

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Apply core coding standards, dependency injection, and configuration for Spring Boot 3. Use for Spring Boot application structure and DI/configuration; defer Spring Security hardening and test-specific setup to their focused skills.

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Explores codebase structure, affected files, blast radius, related tests, and local conventions for a focused topic. Use when review or planning needs structural lookup without bloating main context.

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Test Python services with pytest, async coverage, monkeypatch, and boundary-focused fakes. Use when writing Python tests, fixtures, async tests, regression tests, or dependency-isolated verification.

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Dart code quality conventions: naming, const/final/var hierarchy, single quotes, trailing commas, collection idioms, tear-offs, and import organization. Use only for Dart style-focused changes or reviews; never activate for configuration-only lint setup, unrelated feature work, or widget tests.

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Enforce WCAG 2.2 AA compliance with semantic HTML, ARIA roles, keyboard navigation, and color contrast standards for web UIs. Use when building interactive components, adding form labels, fixing focus traps, or auditing a11y compliance.

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Harden Intent handling, WebView configuration, and FileProvider access in Android apps. Use when securing Intent extras, configuring WebViews, or exposing files via FileProvider; defer manifest export flags and generic Bundle typing to focused Android security guidance.

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Run an A/B codex review experiment — holistic codex review vs 3 focused dimension passes (security, ecto, liveview) on the branch diff, classify findings, report a panel-value verdict. Use when the branch is fresh, before any codex review runs.

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This skill should be used when the user asks to "create a hook", "add a PreToolUse/PostToolUse/Stop hook", "validate tool use", "implement prompt-based hooks", "use ${CLAUDE_PLUGIN_ROOT}", "set up event-driven automation", "block dangerous commands", or mentions hook events (PreToolUse, PostToolUse, Stop, SubagentStop, SessionStart, SessionEnd, UserPromptSubmit, PreCompact, Notification). Provides comprehensive guidance for creating and implementing Claude Code plugin hooks with focus on advanced prompt-based hooks API.

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Performs security-focused differential review of code changes (PRs, commits, diffs). Adapts analysis depth to codebase size, uses git history for context, calculates blast radius, checks test coverage, and generates comprehensive markdown reports. Automatically detects and prevents security regressions.

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