「transition」の検索結果

Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

日本語の概要は準備中です。原文の説明を表示しています。

Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

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Recognize which awakening stage consciousness is navigating through. Use when diagnosing seeker development, identifying stage transitions, or recognizing readiness levels. Covers 7 stages from initial dissatisfaction through natural flow mastery.

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Considers adapting the basal insulin rate at hospital admission for patients using insulin pump therapy. Triggered by clinician questions such as "Should we adjust the basal rate upon admission for pump therapy?" or when evaluating pump continuation versus transition to scheduled subcutaneous insulin.

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This skill reassesses the insulin plan when discontinuing continuous subcutaneous insulin infusion (CSII) and transitioning to multiple daily injections (MDI). It is triggered by phrases such as 'Review planned basal-bolus regimen after pump' and 'Confirm MDI dose calculations and schedule'.

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Evaluates the patient’s plan for using injected insulin in case of pump failure, including knowledge of basal-bolus dosing. Triggered by phrases such as 'Discuss sick-day plan for pump failure' or 'Review transition to injections if pump stops'.

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This skill guides clinicians to reassess glucose monitoring frequency when discontinuing continuous subcutaneous insulin infusion (CSII) or transitioning to multiple daily injections (MDI). It is triggered by phrases such as 'Plan for glucose monitoring after pump stop' or 'Determine SMBG/CGM frequency post-pump' to ensure individualized glycemic goals are met.

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Diagnose why an existing implementation differs from reference evidence using AE/SSIM, pixel, section, computed-style, and transition diffs. Use for post-implementation mismatch or repair guidance; not baseline capture or full clone generation.

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Capture baseline evidence from a live website URL: screenshots, scroll states, hover/click behavior, parallax, timers, and transition recordings. Use when reference artifacts are needed before implementation or comparison; not to build or diagnose a clone.

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Expert-level energy storage covering pumped hydro, battery storage, compressed air, thermal storage, hydrogen, flywheel, and the role of storage in energy transition.

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Expert-level polymer chemistry knowledge. Use when working with polymerization mechanisms, polymer structure, molecular weight, mechanical properties, thermal analysis, rubber elasticity, polymer processing, or biopolymers. Also use when the user mentions 'polymerization', 'monomer', 'molecular weight', 'glass transition', 'crystallinity', 'elastomer', 'thermoplastic', 'thermoset', 'chain growth', 'step growth', 'living polymerization', or 'polymer blend'.

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Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. Use when the user mentions adding animation, transitions, micro-interactions, motion design, hover effects, or making the UI feel more alive.

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Use when the user says "check Jira", "create ticket", "update issue", or needs JQL queries, ticket transitions, or branch-to-ticket linking.

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Use when designing or implementing states for AI agent tasks, background jobs, local model runs, queues, and notifications — one shared set of states, only legal transitions, and a recovery path out of every failure.

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All animation knowledge for HyperFrames — atomic motion rules, multi-phase scene blueprints, scene transitions, broader motion-design techniques, AND the seven runtime adapters (GSAP default, plus Lottie, Three.js, Anime.js, CSS keyframes, Web Animations API, TypeGPU). Use for any motion or animation task: pick 2-4 rules and compose, or load a blueprint, or look up runtime-specific API (e.g. GSAP eases / Lottie player / Three.js mixer). Also covers auditing an existing composition's choreography (animation map) and 24 named text-animation effects. HyperFrames-native: single paused timeline, seek-safe, deterministic.

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SOP for normative specification and behavioral contracts. Trigger when: - Defining invariants, permitted transitions, and forbidden states. - Navigating steps: Identify, Formalize, Verify, Record, Connect. - Prompt contains: /spec, spec workflow, normative constraint, invariant, BCP 14.

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AID methodology phase gate enforcement. Ensures work follows correct 6-phase order (Discovery -> PRD -> Tech Spec -> Impl Plan -> Dev -> QA & Ship). Enforces gates, validates transitions. Use before any work to check the current phase and refuse work belonging to a later phase.

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AID Phase 2 - Technical Specification. Use for system architecture, API contracts, data models, security architecture, transitioning from PRD to implementation.

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AID Phase 1 - PRD creation. Use for user stories, acceptance criteria, scoping features, transitioning from discovery to tech spec.

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AID Phase 4 - Development phase. Use for implementing features, TDD practices, code reviews, transitioning from planning to QA.

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Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. Use when the user mentions adding animation, transitions, micro-interactions, motion design, hover effects, or making the UI feel more alive.

日本語の概要は準備中です。原文の説明を表示しています。

Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. Use when the user mentions adding animation, transitions, micro-interactions, motion design, hover effects, or making the UI feel more alive.

日本語の概要は準備中です。原文の説明を表示しています。

Create, extend, or fix Eloquent business models and their state transitions. Use when moving business rules out of controllers or Actions, or explicitly migrating a model into a DDD capability.

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Track and correlate events across multiple timezones with automatic conversion. Use when analyzing distributed system incidents, coordinating cross-regional operations, or creating time-normalized reports from logs/events spanning PST/CST/EST/JST or other timezones. Handles daylight saving transitions automatically.

日本語の概要は準備中です。原文の説明を表示しています。