「zat」の検索結果

Use when a task needs the judgment of an electric-motor and power-tool repairer — reading a megohmmeter/polarization-index test to catch a winding fault before failure, deciding rewind vs. replace on a failed induction motor, isolating a bearing fault from a broken-rotor-bar fault, judging brush/commutator wear on a universal motor, or evaluating whether a rewind was actually done to spec.

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Use when a task needs the judgment of an Energy Auditor — running a blower-door/duct-leakage diagnostic sequence on a home or light-commercial building, testing combustion appliances for worst-case backdraft risk before recommending air sealing, reconciling utility billing history against walkthrough findings, ranking retrofit measures by savings-to-investment ratio (SIR) for a weatherization or utility rebate program, or writing the prioritized scope of work an install crew executes without the auditor on site. Distinct from an energy-engineer (industrial/commercial capital planning, IPMVP measurement and verification, calibrated simulation) — this role owns the field diagnostics and the residential/light-commercial audit-to-scope handoff.

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Use when a task needs the judgment of an education administrator in a non-traditional setting — adult/continuing education, vocational or trade school, corporate/organizational training department, or other education programs outside standard K-12 or degree-granting postsecondary institutions. Covers the O*NET "Education Administrators, All Other" catch-all.

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Use when a task needs the judgment of an emergency medicine physician — risk-stratifying an undifferentiated chief complaint against a can't-miss diagnosis, deciding an ED disposition (discharge/observation/admit/transfer) under time and bed pressure, reasoning through EMTALA screening-and-stabilization obligations, or triaging a department under crowding/boarding load.

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Use when a task needs the judgment of a Database Architect — choosing a normalization level matched to the actual workload, resolving a CAP theorem tradeoff (consistency vs. availability) for a distributed data store, selecting a sharding/partition key aligned with the dominant query pattern, validating an indexing strategy against real query plans, or deriving RPO/RTO backup and replication requirements from actual business impact.

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Use when a task needs the judgment of a credit authorizer, checker, or clerk — deciding a real-time point-of-sale credit authorization against available credit, verifying a credit application's income/employment documentation, issuing an adverse-action notice on a declined application, or intaking a chargeback/dispute within its filing window. Distinct from a credit analyst, who underwrites commercial credit with a multi-year financial spread and a risk rating — this role runs a high-volume rules engine against a preset limit, it does not assess creditworthiness from first principles.

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Use when a task needs the judgment of a dental assistant — sequencing instrument transfer during a procedure, troubleshooting a retake-worthy radiograph before re-exposing the patient, tracing a failed sterilization-cycle indicator back to the affected instrument batches, or timing a chairside material mix against its working-time window across multiple prepped teeth.

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Use when a task needs the judgment of a Computer and Information Systems Manager (IT Manager/Director/CIO-adjacent) — planning IT infrastructure and systems strategy, evaluating a technology vendor or platform decision, allocating an IT budget, or managing IT risk (security, uptime, technical debt) at an organizational level. Broader than the devops-sre or software-engineer roles — this one owns IT as a business function, not a specific engineering discipline.

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Use when a task needs the judgment of a board-certified cardiologist — triaging chest pain with a risk score, titrating heart-failure guideline-directed medical therapy, deciding revascularization strategy for stable or acute coronary disease, or working through anticoagulation decisions in atrial fibrillation. US practice default (ACC/AHA guideline framework). A reasoning aid, not medical advice.

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Use when a task needs the judgment of a camera-equipment repairer — diagnosing sensor dust vs. lens contamination, deciding whether a shutter is nearing end-of-life and should be replaced vs. repaired, calibrating autofocus and lens collimation, isolating image-stabilization mechanism faults, or sourcing parts for a discontinued body/lens.

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Use when a task needs the judgment of a Biofuels/Biodiesel Technology and Product Development Manager — deciding whether a lab/bench-scale process is ready to scale up, evaluating feedstock flexibility tradeoffs in process design, pricing a technology's value against regulatory credit pathways (RFS RIN, LCFS CI score), or managing IP strategy for a novel conversion process. Distinct from biofuels-production-manager, which runs an existing operating facility — this role owns R&D and commercialization of new or improved process technology.

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Use when a task needs the judgment of a Brewmaster — setting or correcting mash pH before conversion, calibrating yeast pitch rates from wort gravity, deciding whether a diacetyl (VDK) reading clears a batch for cold crash or requires a diacetyl rest, investigating a contamination or off-flavor signal and scoping a recall, or specifying dissolved-oxygen and pasteurization controls to hit a TTB-compliant ABV label.

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Use when a task needs the judgment of a Bioinformatics Scientist — designing a differential-expression or GWAS analysis with correct multiple-testing correction, calling and triaging variants from NGS data using genotype-likelihood confidence rather than raw allele counts, interpreting a BLAST/DIAMOND homology search, choosing or building a genomics pipeline (aligner, caller, normalization method) for a specific data-generating process, or judging whether a computational-biology analysis's statistical design actually supports the biological claim being made. Distinct from a bioinformatics-technician (executes and QC-gates an established pipeline someone else designed) and a data-scientist (general product/experimentation judgment, not genomics-specific statistics) — this role owns which method and statistical model a genomics question requires, and why.

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Use when a task needs the judgment of a Biochemist — determining enzyme kinetics (Km/Vmax, inhibition mechanism) from rate data, choosing a structural-biology method (X-ray crystallography, cryo-EM, or NMR) for a target, designing or interpreting a binding assay (ITC, SPR, fluorescence polarization), or selecting a protein-purification strategy and diagnosing why a prep failed.

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Use when a task needs the judgment of an Application Security Engineer — checking whether an endpoint verifies object-level authorization (not just authentication), running threat modeling at design time rather than deferring security review to the end, triaging a dependency vulnerability by actual reachability rather than CVSS score alone, combining SAST/DAST/SCA tooling to cover their distinct blind spots, or applying context-specific output encoding to untrusted input. Distinct from an information security analyst — this role works inside the SDLC to prevent vulnerabilities before they ship, not detect and respond to intrusions in production.

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Use when a task needs the judgment of a livestock geneticist/animal breeder — selecting a sire against EPDs or genomic data, screening a proposed mating for inbreeding risk, deciding AI versus natural service, timing an estrus-synchronization protocol, or defending a breeding-goal tradeoff to a herd owner.

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Use when a task needs the judgment of an Architecture/Engineering firm or department manager — pricing a project fee (lump sum vs. hourly vs. % of construction cost), staffing a project against backlog, evaluating scope creep on a fixed-fee job, managing professional liability exposure, or deciding whether to pursue a project given current utilization.

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Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and which transcription factors control them?" by layering expression, chromatin accessibility, histone marks, and TF binding data. Follows the Mawla et al. 2023 framework for cross-assay integration of islet cell type-specific data. Handles chromatin state annotation (ChromHMM), enhancer-gene linkage, TF motif enrichment, and cell type-specific regulatory element identification. Use for ANY multi-omic analysis, enhancer discovery, regulatory network construction, or epigenomic characterization using ENCODE data.

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Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact on regulatory elements, perform enrichment testing of variant sets in tissue-specific annotations, or link variants to target genes through enhancer-gene maps. Handles the full post-GWAS workflow from variant set → tissue mapping → functional annotation → fine-mapping awareness → enrichment → variant-to-gene → prioritization. Use this skill for ANY variant interpretation task involving ENCODE chromatin, accessibility, TF binding, or 3D genome data.

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Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal correlation, chromatin state segmentation, enhancer-gene linkage, or any analysis that requires merging or comparing data from two or more ENCODE experiments. Covers same-assay cross-sample, multi-omic same-sample, cross-organism, and perturbation integration designs. Guides compatibility checks, batch effect detection, normalization, integration strategy selection, and provenance documentation.

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Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify chromatin states with ChromHMM, identify super-enhancers with ROSE, understand the functional validation hierarchy (CRISPR > MPRA > reporter), or characterize non-coding genomic regions. Covers the full workflow from ENCODE cCRE lookup through chromatin state segmentation to functional validation and enhancer-gene linkage. Use this skill for ANY regulatory element discovery, classification, or characterization task.

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Spring Security 7 implementation for Spring Boot 4. Use when configuring authentication, authorization, OAuth2/JWT resource servers, method security, or CORS/CSRF. Covers the mandatory Lambda DSL migration, SecurityFilterChain patterns, @PreAuthorize, and password encoding. For testing secured endpoints, see spring-boot-testing skill.

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Spring Boot 4 REST API implementation patterns. Use when creating REST controllers, REST endpoints, request validation, exception handlers with ProblemDetail (RFC 9457), API versioning, content negotiation, WebFlux reactive endpoints, HTTP clients with @HttpExchange, JSON serialization with Jackson 3, error handling, or CORS configuration. Covers @RestController patterns, Bean Validation 3.1, global error handling, and declarative HTTP clients.

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Spring Boot 4 observability with Actuator, Micrometer, and OpenTelemetry. Use when configuring health indicators, health checks, custom metrics, distributed tracing, production endpoint exposure, Kubernetes probes, Cloud Run probes, logging, or monitoring. Covers Actuator endpoint security, Micrometer Timer/Counter/Gauge patterns, OpenTelemetry span customization, liveness/readiness probe setup, and metric tag best practices.

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