664 件 ・ 関連度順
概要と使いどころ
Map Azure architectures and operations to security and compliance controls. Use this skill when users ask for governance, policy enforcement, audit readiness, or regulatory alignment. Covers ISO, SOC2, HIPAA, PCI-DSS, and custom compliance frameworks.
日本語の概要は準備中です。原文の説明を表示しています。
Manages end-to-end workflow for multi-organization amicus coalition briefs in appellate courts. Covers single-pen drafting governance, position alignment, conflict resolution, documented sign-offs, FRAP 29/Rule 37.6 disclosures, FRAP 26.1 corporate disclosures, cover formatting for multiple amici, and compliant filing. Use when coordinating coalition amicus briefs, managing sign-offs, drafting joint friend-of-court briefs, handling multi-amici filing, or resolving inter-organization conflicts. Triggers on phrases like "coalition brief," "12 orgs joining this amicus," or "coordinate the amicus."
日本語の概要は準備中です。原文の説明を表示しています。
Build visual territories (mood boards) for team alignment before production. Groups references into 2-4 named territories, each with palette, texture, typography feel, and 4-6 generated sample tiles, so a team can agree on a direction. Use when the user says "moodboard", "visual territories", "align the team on a look", "reference board", or needs stakeholder sign-off on aesthetic before generating final assets. Part of the Creative Production set.
日本語の概要は準備中です。原文の説明を表示しています。
Decision-theoretic framework for agents embedded within the environments they model and act upon
日本語の概要は準備中です。原文の説明を表示しています。
Matches natural language task descriptions to appropriate skills using semantic similarity. Handles fuzzy matching, intent extraction, and capability alignment. Activate on 'find skill', 'match task', 'semantic search', 'skill lookup', 'what skill for'. NOT for ranking matches (use dag-capability-ranker) or skill catalog (use dag-skill-registry).
日本語の概要は準備中です。原文の説明を表示しています。
Ranks skill matches by fit, performance history, and contextual relevance. Applies multi-factor scoring including success rate, resource usage, and task alignment. Activate on 'rank skills', 'best skill for', 'skill ranking', 'compare skills', 'optimal skill'. NOT for semantic matching (use dag-semantic-matcher) or skill catalog (use dag-skill-registry).
日本語の概要は準備中です。原文の説明を表示しています。
Prepare for Anthropic-specific technical interviews covering Constitutional AI, RLHF, interpretability, scaling laws, MCP, agentic systems, and AI safety. Activate on "anthropic interview", "constitutional AI prep", "alignment interview", "safety interview", "RLHF opinion", "interpretability prep", "anthropic technical". NOT for general ML interview prep, system design interviews, coding challenges, or behavioral interview practice.
日本語の概要は準備中です。原文の説明を表示しています。
Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for visualisation.
日本語の概要は準備中です。原文の説明を表示しています。
Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.
日本語の概要は準備中です。原文の説明を表示しています。
Project gene annotations across genomes using TOGA (Kirilenko 2023 whole-genome-alignment chain-based projection with intactness classification), CESAR 2.0 (Sharma, Schwede & Hiller 2017 codon-aware exon projection), LiftOff (Shumate & Salzberg 2021 reference-based annotation transfer), Liftover (UCSC), GeMoMa (Keilwagen 2019 evidence-based projection), and Comparative Annotation Toolkit (CAT). Use when transferring annotations from a well-annotated reference to query genome(s), classifying gene-loss vs gene-intact across many genomes at scale, building Zoonomia-style comparative annotations across hundreds of mammals or birds (Kirilenko 2023), detecting pseudogenization, projecting alternative isoforms, or selecting between WGA-anchored (TOGA) vs ortholog-based (LiftOff) annotation transfer strategies.
日本語の概要は準備中です。原文の説明を表示しています。
Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.
日本語の概要は準備中です。原文の説明を表示しています。
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective genome size, ENCODE-style IDR vs naive overlap, hyper-ChIPable artifacts, and aligner-specific shifts. Use when calling peaks from ChIP-seq alignments, choosing between narrow vs broad mode for a histone mark, deciding model vs nomodel for low-depth data, applying ENCODE pseudoreplicate IDR, or reconciling MACS vs HOMER vs SPP results.
日本語の概要は準備中です。原文の説明を表示しています。
Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.
日本語の概要は準備中です。原文の説明を表示しています。
Align protein structures using Foldseek 3Di, TM-align, US-align, DALI, or Foldmason for structural MSA. Predict, score, and superpose backbone coordinates when sequence identity is below the twilight zone or remote-homology detection is required. Use when sequence MSA fails (<25% identity), when the dark proteome is the target, when AlphaFoldDB / ESM Atlas search is needed, or when structural superposition is the goal.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Critically review a resume/CV against ATS (applicant tracking system) parsing rules, recruiter skim patterns, and keyword alignment with a target job description. Use when the user asks to "review my resume/CV", "check my resume against this job ad", "will this pass ATS", or shares a resume file (.docx/.pdf/.md) for feedback. Provides scored, prioritised, critical feedback — not a rewrite.
日本語の概要は準備中です。原文の説明を表示しています。
Review a written plan or design doc through a designer's lens before implementation - seven passes over information architecture, interaction states, emotional arc, AI-slop risk, design-system alignment, responsive and accessibility coverage, and unresolved decisions. Each dimension is rated 0-10 with an explicit statement of what would make it a 10, then the plan is edited to get there. Use when a plan has a UI surface and you want the design gaps closed before code is written. Not for auditing a live site.
日本語の概要は準備中です。原文の説明を表示しています。
Frontend UI design, critique, audit, polish. Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Performs a final quality pass fixing alignment, spacing, consistency, and micro-detail issues before shipping. Use when the user mentions polish, finishing touches, pre-launch review, something looks off, or wants to go from good to great.
日本語の概要は準備中です。原文の説明を表示しています。
Improve layout, spacing, and visual rhythm. Fixes monotonous grids, inconsistent spacing, and weak visual hierarchy. Use when the user mentions layout feeling off, spacing issues, visual hierarchy, crowded UI, alignment problems, or wanting better composition.
日本語の概要は準備中です。原文の説明を表示しています。
Creates internal communications for SMEs including employee newsletters, change announcements, town hall agendas, leadership updates, onboarding communications, and team alignment documents. Use when user asks about internal messaging, employee communications, town halls, leadership updates, culture communications, or team announcements.
日本語の概要は準備中です。原文の説明を表示しています。
Use when revising or reviewing scientific, technical, or academic manuscripts, proposals, abstracts, reports, or related writing for precision, concision, logical cohesion, citation support, evidence alignment, and objective scholarly tone.
日本語の概要は準備中です。原文の説明を表示しています。