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MEM, Marker Enrichment Modeling, automatically generates and displays quantitative labels for cell populations that have been identified from single-cell data. The input for MEM is a dataset that has pre-clustered or pre-gated populations with cells in rows and features in columns. Labels convey a list of measured features and the features' levels of relative enrichment on each population. MEM can be applied to a wide variety of data types and can compare between MEM labels from flow cytometry,

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The 'enrichplot' package implements several visualization methods for interpreting functional enrichment results obtained from ORA or GSEA analysis. It is mainly designed to work with the 'clusterProfiler' package suite. All the visualizati

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This package supports functional characteristics of both coding and non-coding genomics data for thousands of species with up-to-date gene annotation. It provides a univeral interface for gene functional annotation from a variety of sources

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Provides Bayesian PCA, Probabilistic PCA, Nipals PCA, Inverse Non-Linear PCA and the conventional SVD PCA. A cluster based method for missing value estimation is included for comparison. BPCA, PPCA and NipalsPCA may be used to perform PCA o

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Expert knowledge for Azure VMware Solution development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when configuring AVS networking/storage, HCX migrations, Horizon/VDI, vSAN clusters, or Azure-integrated backups, and other Azure VMware Solution related development tasks. Not for Azure Virtual Machines (use azure-virtual-machines), Azure Stack Edge (use azure-stack-edge), Azure Nutanix (use azure-nutanix), Azure Red Hat OpenShift (use azure-redhat-openshift).

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Expert knowledge for SAP HANA on Azure Large Instances development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when deploying HANA LIs, Azure Monitor for SAP, HA/DR clusters, Terraform/SDAF automation, or Entra ID SSO, and other SAP HANA on Azure Large Instances related development tasks. Not for Azure Large Instances (use azure-large-instances), Azure Virtual Machines (use azure-virtual-machines), SQL Server on Azure Virtual Machines (use azure-sql-virtual-machines).

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Expert knowledge for Azure Red Hat OpenShift development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when deploying ARO/HCP clusters, configuring networking/storage, securing with Entra/NSGs, or integrating ACR/Key Vault, and other Azure Red Hat OpenShift related development tasks. Not for Azure Kubernetes Service (AKS) (use azure-kubernetes-service), Azure Container Apps (use azure-container-apps), Azure Virtual Machines (use azure-virtual-machines).

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Expert knowledge for Azure Stream Analytics development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when building ASA jobs with Event Hubs/Kafka, Cosmos/SQL outputs, ML/UDF queries, autoscale, or IoT Edge clusters, and other Azure Stream Analytics related development tasks. Not for Azure Synapse Analytics (use azure-synapse-analytics), Azure Data Factory (use azure-data-factory), Azure Event Hubs (use azure-event-hubs), Azure Functions (use azure-functions).

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Expert knowledge for Azure Service Fabric development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when designing Service Fabric clusters, Reliable Services/Actors, reverse proxy/API gateways, CRP/CRM settings, or sfctl automation, and other Azure Service Fabric related development tasks. Not for Azure Kubernetes Service (AKS) (use azure-kubernetes-service), Azure Container Apps (use azure-container-apps), Azure App Service (use azure-app-service), Azure Virtual Machines (use azure-virtual-machines).

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Expert knowledge for Azure Operator Nexus development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, and deployment. Use when configuring Nexus fabric ACLs/BGP, securing RBAC/SSH, planning cluster placement, or diagnosing fabric/K8s issues, and other Azure Operator Nexus related development tasks. Not for Azure Operator Insights (use azure-operator-insights), Azure Operator Service Manager (use azure-operator-service-manager), Azure Networking (use azure-networking), Azure Virtual Network (use azure-virtual-network).

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Expert knowledge for Azure Managed Redis development including troubleshooting, best practices, decision making, architecture & design patterns, security, configuration, integrations & coding patterns, and deployment. Use when using Redis tiers, Entra ID auth, clustering/sharding, persistence/geo-replication, or ARM/Bicep deployments, and other Azure Managed Redis related development tasks. Not for Azure Cache for Redis (use azure-cache-redis).

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Expert knowledge for Azure Local development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when designing Azure Local clusters, SDN networking, multi-rack/disconnected setups, Arc VMs, or Stack HCI deployments, and other Azure Local related development tasks. Not for Microsoft Foundry Local (use microsoft-foundry-local), Azure Stack Edge (use azure-stack-edge), Azure Arc (use azure-arc).

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Expert knowledge for Azure HDInsight development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when working with HDInsight Spark/Hive/Kafka/HBase clusters, Ambari/Oozie pipelines, or Azure-integrated storage/BI, and other Azure HDInsight related development tasks. Not for Azure Databricks (use azure-databricks), Azure Synapse Analytics (use azure-synapse-analytics), Azure Stream Analytics (use azure-stream-analytics).

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Expert knowledge for Azure CycleCloud development including troubleshooting, best practices, decision making, architecture & design patterns, security, configuration, integrations & coding patterns, and deployment. Use when automating CycleCloud via API/CLI/SDK, configuring Slurm clusters, tuning HB/HC VMs, or securing access, and other Azure CycleCloud related development tasks. Not for Azure Batch (use azure-batch), Azure HDInsight (use azure-hdinsight), Azure Databricks (use azure-databricks), Azure Kubernetes Service (AKS) (use azure-kubernetes-service).

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Expert knowledge for Azure Data Explorer development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when securing ADX (RBAC/MI), automating cluster/schema deploys, tuning ingestion/queries, or integrating via ODBC/JDBC/Power BI, and other Azure Data Explorer related development tasks. Not for Azure Synapse Analytics (use azure-synapse-analytics), Azure HDInsight (use azure-hdinsight), Azure Databricks (use azure-databricks), Azure Stream Analytics (use azure-stream-analytics).

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Expert knowledge for Azure Elastic SAN development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when creating Elastic SAN volumes, AVS datastores, iSCSI clients, snapshots, or clustered SQL/FC workloads, and other Azure Elastic SAN related development tasks. Not for Azure Blob Storage (use azure-blob-storage), Azure Files (use azure-files), Azure NetApp Files (use azure-netapp-files), Azure Virtual Machines (use azure-virtual-machines).

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Expert knowledge for Azure Cloud Hsm development including troubleshooting, best practices, limits & quotas, security, and integrations & coding patterns. Use when configuring Cloud HSM auth/networking, PKCS#11 apps, X.509 cert storage, capacity limits, or cluster issues, and other Azure Cloud Hsm related development tasks. Not for Azure Dedicated HSM (use azure-dedicated-hsm), Azure Payment Hsm (use azure-payment-hsm), Azure Key Vault (use azure-key-vault), Azure Attestation (use azure-attestation).

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Expert knowledge for Azure Bastion development including best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, and integrations & coding patterns. Use when configuring Bastion for AKS private clusters, VM scale sets, Entra ID auth, hub/spoke VNets, or IP-based cross-VNet access, and other Azure Bastion related development tasks. Not for Azure Virtual Network (use azure-virtual-network), Azure Virtual Network Manager (use azure-virtual-network-manager), Azure VPN Gateway (use azure-vpn-gateway), Azure Firewall (use azure-firewall).

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Search and curate X/Twitter behind one selector - keyword, topic roundup, a single or tracked-account digest, an X list, or the AI-agent buzz preset - clustered into signal-scored sub-narratives.

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Curated trending across GitHub repos and the Hugging Face Hub (models, datasets, spaces) - filtered, clustered, and labeled by momentum with a one-line why-notable per pick.

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Point Aeon at a service's /feedback endpoint - pull what agents reported (bugs, missing features), triage and cluster it, then build the best accepted request as a PR for a human to approve.

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Perform keyword research using the SemRush API. Use when the user says "find keywords", "keyword research", "what should I rank for", "keyword ideas", "search volume", "keyword difficulty", "topic clusters", "content gaps", or asks about SEO keywords for a topic or niche.

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Detect and investigate bulk registration abuse on SaaS platforms. Given access to a user database (or exported CSV/JSON), run a multi-dimensional anomaly analysis — email domain clustering, registration tempo, UA fingerprinting, session structure, usage patterns, and credit consumption — to produce a scored abuse report with actionable recommendations. Use when investigating suspicious sign-up spikes, credit fraud, free-tier abuse, or account farming.

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Monthly on the last weekday, light browser lane. Re-tests every theme and every severity rule against a month of real ticket evidence and rewrites strategy/themes.md wherever the evidence disagrees with the assumption. It merges two themes the evidence shows are one, splits a theme whose tickets have two different answers, retires a theme with no volume, creates a theme for a cluster that kept landing unclassified, and rewrites a severity rule wherever the outcomes contradict it. Theme ids are never reused and never renumbered. It holds every outbound action unless you released the channel, and it never touches a credential.

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