「lbo」の検索結果

Turns plain-language requests (emails, chat messages, form submissions, meeting asks, voicemail or call notes) into one intake record per request (what is asked, who asks and for whom, urgency as evidenced, category, suggested owner, missing information with draft clarifying questions) and a triage table sorted for the operations lead to act on. Use when the user asks to "log these requests", "triage this pile of asks", "turn this message into an intake record", "who should own this request", "what is missing before we can start" or "build today's intake list". Do not use for customer support tickets, use ticket-triage-pack instead; for clearing a personal mailbox by reply bucket, use inbox-triage. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

Sorts a personal inbox backlog into five buckets (needs-reply-today, needs-reply-this-week, waiting-on-others, FYI, noise), writes DRAFT reply text for the messages that need an answer (up to 10 per run), and returns a dated triage report as one Markdown document. Lists moves or archives only as proposals for the user to perform, and only where a rule the user supplied says so; the agent changes nothing in the mailbox. Use when the user asks to "triage my inbox", "sort my mail", "clean up my inbox", "catch up after leave" or "what needs a reply today or this week". Do not use for a shared support queue or helpdesk export, use ticket-triage-pack instead; for what the user promised or is owed, use commitment-catcher; for one named thread, answer directly. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

Read this machine's cross-machine mailbox, the messages another computer's agent left here over a file-synced bus folder, and send messages back the same way. A session-start hook shows new mail automatically; this is the on-demand mid-session re-check. Triggers: "/inbox", "check inbox", "messages from the other machine".

日本語の概要は準備中です。原文の説明を表示しています。

Check, search or digest Gmail across several mailboxes over the owner's own OAuth connector, with no browser and near-zero tokens for the raw pull. Read-only by default: drafting and sending go through the outbound approval gate. Triggers: "/gmail", "check mail", "any important emails", "find the email about <X>".

日本語の概要は準備中です。原文の説明を表示しています。

Email marketing operations and automation for B2B SaaS. Use this skill for newsletter strategy, email automation sequences, lifecycle campaigns, nurture workflows, onboarding sequences, deliverability optimization, email copywriting, lead scoring, marketing automation platform setup, and cold-email sending infrastructure — secondary sending domains, SPF/DKIM/DMARC, and domain warmup. Also triggers on: email, newsletter, drip campaign, lifecycle, nurture, onboarding sequence, deliverability, email automation, lead scoring, marketing automation, our emails are going to spam, SPF, DKIM, DMARC, sender reputation, sending domain, cold email domains, domain warmup, mailbox setup, blacklist, bounce rate.

日本語の概要は準備中です。原文の説明を表示しています。

Blockly visual programming context for the Megahub project. Use when adding, modifying, or debugging custom Blockly blocks, the Lua code generator, the toolbox, block colors, or the BLOCKS.md documentation generation script.

日本語の概要は準備中です。原文の説明を表示しています。

Build leveraged buyout workbooks with IRR/MOIC in Excel.

日本語の概要は準備中です。原文の説明を表示しています。

Busabase AirApp-first email inbox-zero operator for reviewing unread mail, drafting replies, approving archive/mark-read/send actions, and executing only explicitly approved mailbox changes across configured accounts. Use when the user invokes $kelly-email, asks to process unread email, configure an email account, generate or review an approval batch, execute approved email decisions, or reach inbox zero.

日本語の概要は準備中です。原文の説明を表示しています。

Run a Busabase-backed job-search outreach desk with a bundled Hono App-in-Skill deployable to AirApp. Use when the user invokes $kelly-jobhunt or /kelly-jobhunt, wants to turn a resume into a structured profile and a typeset PDF, wants to find target companies and their contact addresses instead of applying through a job board, wants one tailored application email drafted per company, or wants to review and approve each send. Four subcommands - setup, profile, research, send - plus the desk itself. One company receives exactly one email; mailbox credentials live in the Busabase Vault and never reach browser code.

日本語の概要は準備中です。原文の説明を表示しています。

Renders Hi-C contact matrices honestly and reproducibly with matplotlib, cooltools, HiCExplorer, pyGenomeTracks, FAN-C, CoolBox, and plotgardener. Covers the raw/ICE-balanced/observed-over-expected transform choice, LogNorm vs symmetric-diverging colormaps with vmax/percentile clipping, resolution-to-feature matching (compartments 100-500kb, TADs 10-40kb, loops 5-10kb), square vs rotated-triangle track-stacking, NaN/white-stripe handling, virtual 4C, APA/saddle/on-diagonal pileups, two-condition side-by-side and log2-ratio maps, and interactive (HiGlass) vs scripted-static publication figures. Use when plotting a contact matrix, choosing a normalization or color scale, building a multi-track Hi-C figure, making a virtual 4C profile, piling up loops/boundaries, or comparing two conditions.

日本語の概要は準備中です。原文の説明を表示しています。

Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction read per cell per AS event). Plate-based full-length methods (Smart-seq3, FLASH-seq, VASA-seq, STORM-seq) and single-cell long-read (MAS-Iso-seq, scISOr-Seq2) are the chemistries that give per-cell isoform structure. Tools include MARVEL (R, Smart-seq integrated), BRIE2 (Bayesian PSI with regulatory features and ELBO_gain test), scQuint (junction-cluster, plate-based; not for 10X), SpliZ (annotation-free Z-score), Psix (graph-smoothness regulated AS), and Sierra (alternative polyadenylation, often confused with AS). Use when analyzing isoform usage in scRNA-seq, identifying cell-type-specific splicing, or determining whether scRNA-seq chemistry supports splicing analysis at all.

日本語の概要は準備中です。原文の説明を表示しています。

Renders Hi-C contact matrices honestly and reproducibly with matplotlib, cooltools, HiCExplorer, pyGenomeTracks, FAN-C, CoolBox, and plotgardener. Covers the raw/ICE-balanced/observed-over-expected transform choice, LogNorm vs symmetric-diverging colormaps with vmax/percentile clipping, resolution-to-feature matching (compartments 100-500kb, TADs 10-40kb, loops 5-10kb), square vs rotated-triangle track-stacking, NaN/white-stripe handling, virtual 4C, APA/saddle/on-diagonal pileups, two-condition side-by-side and log2-ratio maps, and interactive (HiGlass) vs scripted-static publication figures. Use when plotting a contact matrix, choosing a normalization or color scale, building a multi-track Hi-C figure, making a virtual 4C profile, piling up loops/boundaries, or comparing two conditions.

日本語の概要は準備中です。原文の説明を表示しています。

Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction read per cell per AS event). Plate-based full-length methods (Smart-seq3, FLASH-seq, VASA-seq, STORM-seq) and single-cell long-read (MAS-Iso-seq, scISOr-Seq2) are the chemistries that give per-cell isoform structure. Tools include MARVEL (R, Smart-seq integrated), BRIE2 (Bayesian PSI with regulatory features and ELBO_gain test), scQuint (junction-cluster, plate-based; not for 10X), SpliZ (annotation-free Z-score), Psix (graph-smoothness regulated AS), and Sierra (alternative polyadenylation, often confused with AS). Use when analyzing isoform usage in scRNA-seq, identifying cell-type-specific splicing, or determining whether scRNA-seq chemistry supports splicing analysis at all.

日本語の概要は準備中です。原文の説明を表示しています。

Read and manage email via IMAP (ProtonMail Bridge, Gmail, etc.). Check for new/unread messages, fetch content, search mailboxes, and mark as read/unread. Works with any IMAP server including ProtonMail Bridge.

日本語の概要は準備中です。原文の説明を表示しています。

Read and manage email via IMAP (ProtonMail Bridge, Gmail, etc.). Check for new/unread messages, fetch content, search mailboxes, and mark as read/unread. Works with any IMAP server including ProtonMail Bridge.

日本語の概要は準備中です。原文の説明を表示しています。

Expert-level idiomatic Rust API design — the patterns that make illegal states unrepresentable and abstractions zero-cost. Type-state programming (PhantomData state machines), newtype + sealed + extension traits, typestate builders, RAII guards & Drop ordering, the interior-mutability decision tree (Cell/RefCell/Mutex/RwLock/Atomic/OnceLock), enum-driven state machines, error architecture (thiserror vs anyhow), dyn vs generic dispatch & object safety, the impl Trait / GAT / RPITIT toolbox, and Deref-for-smart-pointers (and its abuse). Use when designing a Rust library's public API, encoding invariants in the type system, choosing a dispatch or error strategy, or reviewing Rust for idiom. NOT for borrow-checker firefighting / toolchain / test-runner workflow (use rust-development-workflow), NOT for pd-console GPUI rendering/layout/panes (use gpui-rust-console), NOT for app packaging/notarization (use rust-app-distribution).

日本語の概要は準備中です。原文の説明を表示しています。