「signing」の検索結果

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.

日本語の概要は準備中です。原文の説明を表示しています。

Use when accepting ANY real-world payment — Apple Pay, Wallet passes, Tap to Pay, Orders in Wallet. NOT in-app purchase / digital content (use axiom-integration). Covers entitlements, certs, signing, App Review payment rules.

日本語の概要は準備中です。原文の説明を表示しています。

Use when storing credentials securely, encrypting data, implementing passkeys, securing AI/agentic features against prompt injection, code signing, or managing certificates and provisioning profiles.

日本語の概要は準備中です。原文の説明を表示しています。

Formats and parses locale-aware numbers, decimals, currencies, percentages, dates, durations, measurements, names, lists, byte counts, and URLs with Foundation FormatStyle and ParseableFormatStyle. Use when replacing legacy Formatter subclasses, designing reusable format APIs, using SwiftUI Text(_:format:), correcting availability, or testing user-facing formatted output across locales.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve Swift concurrency compiler errors, adopt approachable concurrency (SE-0466), and write data-race-safe async code. Use when fixing Sendable conformance errors, actor isolation warnings, or strict concurrency diagnostics; when adopting default MainActor isolation, @concurrent, nonisolated(nonsending), or Task.immediate; when designing actor-based architectures, structured concurrency with TaskGroup, or background work offloading; or when migrating from @preconcurrency to full Swift 6 strict concurrency.

日本語の概要は準備中です。原文の説明を表示しています。

Apply Swift API Design Guidelines to name, label, and document Swift APIs. Covers argument label rules (prepositional phrase rule, grammatical phrase rule, first-label omission), mutating/nonmutating pair naming (-ed/-ing participle pattern, form- prefix, sort/sorted, formUnion/union), side-effect naming (noun for pure, verb for mutating), documentation comment structure (summary by declaration kind, O(1) complexity rule), clarity at call site, role-based naming, protocol naming (-able/-ible/-ing), default arguments over method families, casing conventions, and terminology. Use when designing new Swift APIs, reviewing naming and argument labels, writing documentation comments, or refactoring for call site clarity.

日本語の概要は準備中です。原文の説明を表示しています。

Use Apple CryptoKit for Swift cryptographic primitives. Use when hashing with SHA-2 or SHA-3, generating HMACs, encrypting with AES-GCM or ChaChaPoly, signing with P256/P384/P521/Curve25519 or ML-DSA keys, performing ECDH, HPKE, ML-KEM, or X-Wing key exchange, using Secure Enclave CryptoKit keys, or migrating CommonCrypto code to CryptoKit.

日本語の概要は準備中です。原文の説明を表示しています。

MongoDB schema design patterns and anti-patterns. Use when designing data models, reviewing schemas, migrating from SQL, or troubleshooting performance issues caused by schema problems. Triggers on "design schema", "embed vs reference", "MongoDB data model", "schema review", "unbounded arrays", "one-to-many", "tree structure", "16MB limit", "schema validation", "JSON Schema", "time series", "schema migration", "polymorphic", "TTL", "data lifecycle", "archive", "index explosion", "unnecessary indexes", "approximation pattern", "document versioning".

日本語の概要は準備中です。原文の説明を表示しています。

Guides Metronome usage-based billing integration decisions — event ingestion (single and batch, idempotency, billable metrics), contract design (rate cards, overrides, dimensional pricing, products), invoicing lifecycle (grace periods, finalization, Stripe sync), credit and commit management (prepaid, postpaid, thresholds, auto-recharge), and Stripe integration (arrears invoicing, tax providers, line item limits). Use when building, modifying, or reviewing any Metronome integration — including ingesting usage events, creating customers, contracts, or rate cards, designing billable metric group keys, managing credits and commits, configuring invoicing, syncing invoices with Stripe Billing, billing AI applications for token usage, setting up self-serve (PLG) pricing, reviewing customer health, commit burn, portfolios, or renewals, or migrating from Stripe Billing Meters to Metronome.

日本語の概要は準備中です。原文の説明を表示しています。

React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

日本語の概要は準備中です。原文の説明を表示しています。

Deploys and operates a LiveKit agent in production: shipping a version to LiveKit Cloud and rolling it back, secrets and configuration, the worker process model and prewarming, safe async inside worker processes, provider timeouts and degradation, graceful shutdown, SDK upgrades, and observability. Use when the user says "deploy my agent", "roll back the deployment", "tail the agent logs", "the first call after a restart is slow", "attached to a different loop / event loop is closed", "prewarm the VAD", "shut down without dropping calls", "upgrade livekit-agents safely", "correlate logs by session", or is changing an agent codebase that is already live. Not for designing the agent (building-livekit-agents) or reproducing one bad conversation locally (debugging-livekit-agents).

日本語の概要は準備中です。原文の説明を表示しています。

Cascade PCB components, add lumped elements, export Touchstone, and bridge to eye diagram or antenna array workflows. TRIGGER: user asks to cascade or connect multiple RF PCB components, add lumped R/L/C, export S-parameters to Touchstone, or combine PCB elements into a circuit. Invoke BEFORE writing pcbcascade or circuit code — cascade rules and port matching are non-obvious. SKIP: designing individual components (use the specific matlab-design-pcb-* skill), EM analysis of a single component (use matlab-analyze-em), material/stackup setup only (use matlab-manage-pcb-material), optimization (use matlab-optimize-pcb-design).

日本語の概要は準備中です。原文の説明を表示しています。

Optimize RF PCB dimensions for bandwidth, return loss, or area via patternsearch and surrogateopt with constraints. TRIGGER: user asks to optimize an RF PCB component for performance (bandwidth, return loss, insertion loss, area) or apply constraints to a design. Invoke BEFORE writing optimization code — RF PCB Toolbox has a built-in optimize() function that differs from generic fmincon/ga approaches. SKIP: designing a component from scratch without an optimization objective (use the specific matlab-design-pcb-* skill), EM analysis without optimization (use matlab-analyze-em), material/stackup setup only (use matlab-manage-pcb-material).

日本語の概要は準備中です。原文の説明を表示しています。

Design and validate digital filters in MATLAB. Use when cleaning up noisy signals, removing interference, filtering signals, designing FIR/IIR filters (lowpass/highpass/bandpass/bandstop/notch), or comparing filters in Filter Analyzer.

日本語の概要は準備中です。原文の説明を表示しています。

Use when designing a Digital Down Converter (DDC) using dsphdl System objects. Triggers on requests involving DDC design, frequency down-conversion for FPGA/ASIC, NCO + mixer + decimation filter chains, fractional/non-integer sample rate conversion, or HDL-optimized receiver front-end signal processing.

日本語の概要は準備中です。原文の説明を表示しています。

Build industrial-grade SCADA/HMI dashboards in MATLAB following industrial-HMI conventions (ISA-101-aligned): gray-field philosophy, alarms at source, write safeguards, fixed-range trends, drill-down layout. Produces a real App Designer app (.mlapp, or plain-text .m+.xml on R2026b+) by handing serialization to the matlab-build-app skill when available, and falls back to a programmatic .m app otherwise. Use when wrapping OPC UA / Modbus / MQTT / OSI PI / PI AF monitoring scripts into a live operator app, building plant overviews, designing operator dashboards, or any time a user asks for a "SCADA dashboard", "HMI", "plant dashboard", "operator screen", or "industrial monitoring app" in MATLAB. Trigger on: SCADA, HMI, industrial dashboard, plant overview, operator screen, uigauge, uilamp, alarm banner, gray-field, ISA-101, OPC UA dashboard, setpoint, write safeguards, alarm visualization, OSIsoft PI, AVEVA PI, PI Server, PI Data Archive, PI AF, PI Asset Framework, piclient, afclient.

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Read BEFORE writing any code that builds or simulates OFDM systems. The default MATLAB patterns for OFDM (e.g., direct ifft/fft, awgn with 0 dBW power, missing symOffset) produce subtly incorrect results — always use ofdmmod/ofdmdemod instead of direct IFFT/FFT. This skill specifies the correct calling conventions for ofdmmod, ofdmdemod, ofdmChannelResponse, ofdmEqualize, and critical anti-patterns that must be avoided. Use when building OFDM transmitters or receivers, allocating subcarriers and guard bands, inserting pilots, computing SNR for OFDM, configuring fading channels (Rayleigh/Rician), estimating and equalizing channels, implementing timing and frequency synchronization, adding LDPC coding, designing resource grids, or setting up OFDM link simulations.

日本語の概要は準備中です。原文の説明を表示しています。

Build custom PCB structures with pcbComponent, shapes, Boolean ops, feeds, and multi-layer stackups for non-catalog geometries. TRIGGER: user asks to build, modify, or customize a pcbComponent — add/remove shapes, edit polygons, place feeds, add metal layers, cut slots, or create non-catalog RF structures. Also when modifying geometry of an existing catalog-designed component (e.g., adding pads, removing elements, editing vertices). Invoke BEFORE writing pcbComponent code — layer/shape/feed API is non-obvious. SKIP: designing catalog components like filters/couplers/txlines (use the specific matlab-design-pcb-* skill), material/stackup definition only (use matlab-manage-pcb-material), EM analysis (use matlab-analyze-em), importing PCB files (use matlab-read-pcb-layout).

日本語の概要は準備中です。原文の説明を表示しています。

Launch and control the MATLAB Radar Designer app programmatically via MCP. Use when designing radar systems, configuring parameters, comparing radar types, analyzing performance metrics, or managing radar design sessions.

日本語の概要は準備中です。原文の説明を表示しています。

S-parameters, insertion loss, fields, currents, mesh control, and solver selection for RF PCB performance validation. TRIGGER: user asks to compute S-parameters, analyze insertion/return loss, extract fields or currents, compare MoM vs FEM, or control mesh for any RF PCB component. Invoke BEFORE writing sparameters() or solver code — API is non-obvious. SKIP: designing or creating components (use the specific matlab-design-pcb-* skill), material/stackup setup only (use matlab-manage-pcb-material), optimization sweeps (use matlab-optimize-pcb-design), PDN/IR-drop analysis (use matlab-analyze-pcb-pdn).

日本語の概要は準備中です。原文の説明を表示しています。

RoadRunner asset path lookup tables for map format conversions in MATLAB. Maps lane markings, signs, signals, barriers, objects, and lane types to RoadRunner asset paths. Use when converting map formats to RRHD, resolving asset paths, or assigning visual assets to HD Map objects.

日本語の概要は準備中です。原文の説明を表示しています。

AWS DynamoDB NoSQL database for scalable data storage. Use when designing table schemas, writing queries, configuring indexes, managing capacity, implementing single-table design, or troubleshooting performance issues.

日本語の概要は準備中です。原文の説明を表示しています。

AWS Step Functions workflow orchestration with state machines. Use when designing workflows, implementing error handling, configuring parallel execution, integrating with AWS services, or debugging executions.

日本語の概要は準備中です。原文の説明を表示しています。