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Designs PROTACs, molecular glues, and bivalent degraders with explicit handling of E3 ligase choice (VHL, CRBN, IAP, MDM2, KEAP1), linker design (length, composition, rigidity), ternary complex prediction (PRosettaC, DeepTernary, AlphaFold3), cooperativity (alpha), DC50 / Dmax characterization, hook effect, and prediction-experiment reconciliation. Use when designing targeted protein degraders, planning linker SAR, predicting ternary complex stability, or building generative degrader workflows.

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Analyzes chemical libraries by scaffold using Bemis-Murcko scaffolds, generic frameworks, cyclic skeletons, matched molecular pair (MMP) analysis via mmpdb, R-group decomposition, Free-Wilson analysis, scaffold hopping, and chemotype-aware ML train/test splits. Use when identifying chemotype clusters in a library, deriving SAR transformation rules, decomposing series into R-groups, performing scaffold-balanced QSAR splits, or planning analog campaigns.

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Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.

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Validates docked / generated protein-ligand poses using PoseBusters physical-validity tests, strain energy quantification, geometric checks (planarity, vdW overlap, bond/angle distortion), and pose-energy reasonableness. Use when QC-ing docking results, comparing classical vs ML docking outputs, or filtering pose lists before SAR analysis.

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Build iOS augmented reality and 3D experiences with RealityKit and ARKit. Use when adding RealityView content, loading entities or USDZ models, anchoring objects to planes or world positions, distinguishing entity hit tests from ARKit real-world raycasts, handling AR camera availability, world tracking, scene updates, or RealityKit entity gestures and interactions.

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Selects, reviews, and migrates Apple-platform app architectures across MV with Observation, MVVM, MVI, TCA, Clean Architecture, Coordinator, and legacy VIPER. Use when choosing module and dependency boundaries, escalating a feature beyond simple SwiftUI MV, planning incremental architecture migration, or auditing state ownership and test seams.

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Maintain and extend existing SceneKit 3D scenes and visualizations. Use when working with SCNView, SCNScene, SCNNode scene graphs, SceneKit geometry/materials/lights/cameras, SCNAction animation, SCNPhysicsBody physics, SCNParticleSystem effects, .scn/.dae/.abc SceneKit assets, shader modifiers, or SwiftUI SceneView. SceneKit is soft-deprecated and in maintenance mode; route new apps, significant updates, USD/USDZ pipelines, and migration planning toward RealityKit.

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Integrate Core ML models in iOS apps for on-device machine learning inference. Covers model loading (.mlmodel, .mlpackage, .mlmodelc), predictions with auto-generated classes and MLFeatureProvider, compute unit configuration (CPU, GPU, Neural Engine), MLTensor, VNCoreMLRequest, MLComputePlan, multi-model pipelines, and deployment strategies. Use when loading Core ML models, making predictions, configuring compute units, or profiling model performance.

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Answer one named planning question with observations tied to the inspected sources; do not write or coordinate the roadmap.

日本語の概要は準備中です。原文の説明を表示しています。

Report the compatibility redirect to `ap-roadmap-author`; this retired role cannot perform new work.

日本語の概要は準備中です。原文の説明を表示しています。

TikTok Shop deals — Flash Deals, vouchers, free shipping, bundle deals, promotion planning

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Inventory management for TikTok Shop — demand forecasting, viral stock planning, FBT optimization

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Seasonal selling calendar — holiday prep, trending categories, listing refresh timing, inventory planning

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Design a controlled dynamic-pricing or repricing system for ecommerce products. Use when a seller asks for demand-based, inventory-based, competitor-responsive, or time-based price rules; SKU eligibility; price floors and ceilings; automation approvals; simulations; monitoring; or rollback plans across Amazon, Shopify, TikTok Shop, Walmart, eBay, or other channels. Do not use for a one-time optimal-price calculation or to change live prices without explicit authorization.

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E-commerce growth strategy advisor. Diagnoses current business health using unit economics (CAC, LTV, AOV, contribution margin), identifies the highest-impact growth opportunities across 5 levers (traffic, conversion, AOV, retention, expansion), and builds a prioritized 90-day growth roadmap. Uses the Ansoff Matrix adapted for e-commerce to evaluate market penetration, channel expansion, product expansion, and new market entry. Includes multichannel readiness assessment (Amazon, Walmart, TikTok Shop, Etsy, DTC/Shopify/Shopify) and product line expansion analysis. No API key required. Use when: (1) planning next phase of e-commerce growth, (2) deciding whether to expand to new channels or products, (3) diagnosing why growth has stalled, (4) prioritizing what to fix or build next.

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Etsy SEO analyzer and optimizer. Improve search visibility with title optimization, tag analysis, description scoring, and keyword research. Includes SEO scoring (0-100), long-tail keyword suggestions, and prioritized action plans. No API key required.

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Social media marketing strategy for ecommerce brands. Content calendar planning, platform-specific strategies, social commerce optimization, influencer collaboration, and community building. Use when the user asks about social media marketing, social commerce, content strategy, or social media for ecommerce.

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Plan and execute e-commerce product launches. Pre-launch, launch day, and post-launch playbooks for Amazon, Shopify, and multi-channel sellers. Covers inventory, pricing, advertising, and review strategy.

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Digital product creation and selling — templates, printables, planners, digital art, delivery setup

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E-commerce email marketing system builder. Creates complete email automation flows with full copywriting, subject lines, ESP setup instructions, segmentation rules, and annual campaign calendars. Generates copy-paste-ready email sequences for Klaviyo, Omnisend, Mailchimp, or any ESP. Covers welcome series, cart abandonment, browse abandonment, post-purchase, review requests, cross-sell, win-back, VIP/loyalty, replenishment, and sunset flows. Includes A/B test subject line variants, send timing, trigger conditions, branching logic, and seasonal campaign calendar. No API key required. Use when: (1) setting up email marketing for an e-commerce store, (2) writing email sequences and flows, (3) planning seasonal email campaigns.

日本語の概要は準備中です。原文の説明を表示しています。

Microstrip, stripline, CPW, differential pairs, and crosstalk analysis for impedance-controlled PCB interconnects. TRIGGER: user asks to design or analyze a transmission line (microstrip, stripline, CPW, coplanar, differential pair), extract RLGC or per-unit-length parameters, compute trace impedance, analyze a PCB trace cross-section, or perform crosstalk/coupling analysis. Invoke BEFORE writing code — preferred over RF Toolbox analytical functions (txlineMicrostrip, txlineStripline, txlineCPW). SKIP: EM simulation/S-parameter extraction of an existing component (use matlab-analyze-em), material/stackup definition only (use matlab-manage-pcb-material), building custom non-catalog geometry (use matlab-assemble-pcb-layout), optimization sweeps (use matlab-optimize-pcb-design).

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Integrate antennas into RF systems using MATLAB Antenna Toolbox and RF Toolbox. Covers impedance matching network design (L/Pi/Tee topologies, evaluation parameters, Richards transformation), measured antenna creation (E-field, directivity-only, EmbeddedE, ffsReader import), RF propagation and site planning (txsite/rxsite, coverage, SINR, ray tracing, link budget), and SAR estimation (birdcage+Phantom, conformalArray+Custom3D, direct EHfields). Use when the user wants to match an antenna, create a measuredAntenna, compute coverage or signal strength, perform ray tracing, or estimate SAR.

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Build MATLAB apps from requirements to working code. Asks discovery questions (or skips them when the path is known), recommends UIFigure or UIHTML architecture, identifies layout archetype (Dashboard, Explorer, Tabbed, Wizard, Canvas), produces an implementation plan, and executes the build. For UIFigure apps, optionally serializes as App Designer (.mlapp or plain-text .m + .xml). Use when a user wants to build a MATLAB app, create a GUI, make an interactive tool, build a uifigure app, build a uihtml app, build an App Designer app, build a .mlapp app, build a plain-text App Designer app, or asks which approach to use. Also use when user describes spatial layout needs: dashboard, control panel, sidebar, tabs, wizard, stepper, canvas, workspace.

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Use this skill when fitting accelerated life models, computing mean time to failure (MTTF), B10 life and similar quantities, fitting life distributions like Weibull for reliability analysis, comparing distribution fits, computing confidence intervals on reliability quantities with bootstrapping, performing lifetime prediction, computing failure rates, plotting Kaplan-Meier curves, computing survival functions, or doing reliability analysis.

日本語の概要は準備中です。原文の説明を表示しています。