「can」の検索結果

Security audit orchestrator for agent skills — scans for prompt injection, data exfiltration, credential theft, supply chain risks, and instruction hierarchy violations before any skill is installed, created, improved, or read from a GitHub repo. Load when creating skills from external sources, when improve-skills reads from GitHub repos, when research-skill fetches community SKILL.md files, when a user installs a third-party skill, or when the user asks to audit skill security, scan for injection, check if a skill is safe, scan all skills, or run a security sweep. Orchestrates all secure-* skills in sequence. Content is SAFE only if ALL secure-* skills return SAFE. 36% of community skills contain flaws (Snyk ToxicSkills 2026). This skill is the first line of defense.

日本語の概要は準備中です。原文の説明を表示しています。

Orchestrator for the pre-decision business-idea lifecycle — generate ideas, model them, evaluate them, validate them with customers, and only then hand off to product-soul / brainstorming. Routes through `idea-generation`, `business-modeling`, `idea-evaluation`, and `customer-discovery`. Load when the user asks to explore business ideas, find a startup idea, evaluate a venture, validate an idea, says "what business should I start", "should I build this", "is this a good business", "I have a startup idea", "evaluate this venture", "model this business", "validate this idea", "Mom Test this", "Lean Canvas this", "Business Model Canvas", "Value Proposition Canvas", "go/no-go on this idea". Pre-decision suite — once one idea is committed, hands off to `product-soul`. Does NOT design features (use `brainstorming`) or audit built products (use `reality-check`).

日本語の概要は準備中です。原文の説明を表示しています。

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Predict peptide-MHC class I binding and natural presentation with MHCflurry, NetMHCpan-4.1, and MixMHCpred to nominate candidate CD8 T-cell epitopes. Covers the binding-affinity (BA) vs eluted-ligand (EL/presentation) distinction, why %Rank beats raw nM for cross-allele work, the MS abundance bias that misranks low-expression neoantigens, allele-coverage inequity, and length bias. Use when scanning a protein or peptide set for class I epitopes, scoring neoantigen candidates, or choosing a binding predictor. For CD4/HLA class II see mhc-class-ii-prediction.

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Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot with 5'UTR / CDS / 3'UTR scaling; MetaPlotR; deepTools `computeMatrix scale-regions`), peak-centred heatmaps (ComplexHeatmap; deepTools plotHeatmap), IP-vs-input paired browser tracks (bigWig of log2 IP/input via deepTools `bamCompare`; ggcoverage; pyGenomeTracks; Gviz; IGV / UCSC track hubs), DRACH sequence-logo plots (ggseqlogo; MEME), 5'UTR / CDS / 3'UTR stacked-bar feature-distribution summaries, and volcano / MA plots for differential modification. Establishes stop-codon enrichment in the metagene plot as the biological QC anchor for any MeRIP dataset (Dominissini 2012 *Nature* 485:201; Meyer 2012 *Cell* 149:1635 — concurrent founding papers from different labs both showed this independently). Use when producing the canonical metagene plot with stop-codon enrichment as a QC anchor, building paired IP/input genome-browser tracks at single-locus resolution, plotting peak-centred heatmaps clustered by condition, summarising peak distribution across transcript features for figure 1, generating DRACH motif logos as sanity checks on the peak set, rendering volcano plots of differential m6A, or reproducing the Dominissini 2012 / Meyer 2012 stop-codon enrichment plot.

日本語の概要は準備中です。原文の説明を表示しています。

Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation conventions. Covers EnhancedVolcano, ggplot2, matplotlib, and the apeglm/ashr/normal shrinkage decision. Use when visualizing differential-expression results (RNA-seq, ChIP-seq, ATAC-seq, proteomics) or any per-feature effect-size + p-value table.

日本語の概要は準備中です。原文の説明を表示しています。

Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautomer canonicalization, stereochemistry standardization, mixture handling, and isotope normalization. Explicitly compares ChEMBL pipeline, canSARchem, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.

日本語の概要は準備中です。原文の説明を表示しています。

Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD-confounded signal under the Schmidt 2020 cis-MR framework, screening on-target adverse phenotypes pheWAS-style, or producing publication-grade STROBE-MR plus PP.H4 evidence for a target gene.

日本語の概要は準備中です。原文の説明を表示しています。

Expert in temporal event detection, spatio-temporal clustering (ST-DBSCAN), and photo context understanding. Use for detecting photo events, clustering by time/location, shareability prediction, place recognition, event significance scoring, and life event detection. Activate on 'event detection', 'temporal clustering', 'ST-DBSCAN', 'spatio-temporal', 'shareability prediction', 'place recognition', 'life events', 'photo events', 'temporal diversity'. NOT for individual photo aesthetic quality (use photo-composition-critic), color palette analysis (use color-theory-palette-harmony-expert), face recognition implementation (use photo-content-recognition-curation-expert), or basic EXIF timestamp extraction.

日本語の概要は準備中です。原文の説明を表示しています。

Blue-green and canary deployment orchestrator with traffic shifting and automated rollback. Activate on: blue-green deployment, canary release, rolling deployment, traffic shifting, rollback automation, progressive delivery, Argo Rollouts, Flagger. NOT for: K8s manifest generation (use kubernetes-manifest-generator), CI/CD pipeline setup (use github-actions-pipeline-builder), monitoring (use monitoring-stack-deployer).

日本語の概要は準備中です。原文の説明を表示しています。

Collapsing every copy of one kind of thing (tables, UIs, utilities, hooks, APIs, renderers) into a single canonical one. Use when asked to unify, merge, converge, or 'make one X used everywhere', or before migrating callers onto a new canonical piece. NOT for docs (use docs).

日本語の概要は準備中です。原文の説明を表示しています。

The re-measure and standing report of the canonical data model's live DB conformance. Use when asked 'where are we at' on DB drift or conformance, to update the drift numbers, when a drift-audit brief is re-issued, or on /drift-audit. NOT the per-table fix recipe (use matrx-frontend's db-canonicalize-table).

日本語の概要は準備中です。原文の説明を表示しています。

Drafts formal explanation letters for Canadian Study Permit applications by structuring the argument around program attractiveness, background relevance, choice rationale, and family benefits.

日本語の概要は準備中です。原文の説明を表示しています。

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

日本語の概要は準備中です。原文の説明を表示しています。

Scan global talent markets via GitHub/Arxiv/LinkedIn APIs, build talent heatmaps with salary benchmarks, identify Tier S/A/B/C candidates. Use when: quarterly talent scanning, critical role hiring, competitive intelligence on talent pools. Includes real API integrations and data pipeline.

日本語の概要は準備中です。原文の説明を表示しています。

Canvas LMS integration — fetch enrolled courses and assignments using API token authentication.

日本語の概要は準備中です。原文の説明を表示しています。

Configures Fail2ban with custom filters and actions to detect port scanning activity, SSH brute force attempts, and network reconnaissance, automatically banning offending IP addresses and alerting security teams to suspicious network probing.

日本語の概要は準備中です。原文の説明を表示しています。

Deploys canary files (honeytokens) across file systems to detect ransomware encryption activity in real time. Uses strategically placed decoy documents monitored via file integrity monitoring or OS-level watchdogs to trigger alerts when ransomware modifies or encrypts them. Activates for requests involving ransomware canary deployment, honeyfile setup, deception-based ransomware detection, or file integrity monitoring for encryption.

日本語の概要は準備中です。原文の説明を表示しています。

URLScan.io is a free service for scanning and analyzing suspicious URLs. It captures screenshots, DOM content, HTTP transactions, JavaScript behavior, and network connections of web pages in an isolat

日本語の概要は準備中です。原文の説明を表示しています。

Manage the canary token honeypot system for detecting security scanning

日本語の概要は準備中です。原文の説明を表示しています。

Detects leaked API keys, tokens, passwords, and credentials in code with pre-commit hooks, CI checks, scanning rules, and remediation procedures. Use for "secret scanning", "credential detection", "API key leaks", or "secret management".

日本語の概要は準備中です。原文の説明を表示しています。

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

日本語の概要は準備中です。原文の説明を表示しています。

OpenClawの画面をSolid 2で実装・移行・レビューするスキル。状態管理やLitとの共存、ダイアログなどの表示、テストと性能確認を扱います。

• Litの画面をSolid 2へ移行したいとき
• 状態管理と画面更新をレビューしたいとき
• プラグイン画面やダイアログの実装