「esi」の検索結果

Designs human-in-the-loop review points for DAG workflows. Determines what to present to the human, how to collect feedback, and how to route approve/reject/modify decisions back into the DAG. Use when adding approval gates, designing review UX, or handling human feedback in agent workflows. Activate on "human review", "approval gate", "human-in-the-loop", "human gate", "approval workflow", "user review step". NOT for executing human gates at runtime (use dag-runtime with Temporal signals), general UX design, or chatbot conversation design.

日本語の概要は準備中です。原文の説明を表示しています。

Long-running design anthropologist that builds comprehensive visual databases from 500-1000 real-world examples, extracting color palettes, typography patterns, layout systems, and interaction design across any domain (portfolios, e-commerce, SaaS, adult content, technical showcases). This skill should be used when users need exhaustive design research, pattern recognition across large example sets, or systematic visual analysis for competitive positioning.

日本語の概要は準備中です。原文の説明を表示しています。

Design and build beautiful, accessible graphical interfaces — web, desktop (Electron/Tauri), and native (iOS/macOS/Android). Use for visual hierarchy and layout, color and theming (light/dark, semantic tokens, WCAG contrast), typography systems, motion and micro-interactions, accessibility, component systems and design tokens, responsive/adaptive layout, and platform-native idioms. The GUI counterpart to beautiful-cli-design. NOT for terminal/CLI output (use beautiful-cli-design) or API/data schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Design decisions for when and what sounds to use in web apps, mobile apps, and desktop native apps — plus how to create them with AI. Covers UI sound vocabulary (confirms, alerts, transitions, errors), platform conventions (iOS, macOS, Material), creating sounds with AI tools (ElevenLabs, AudioCraft, Stable Audio), Web Audio API for procedural sounds, haptic-audio pairing, and the psychology of satisfying vs. annoying UI sounds. Activate on 'app sounds', 'UI sounds', 'notification sound', 'sound design app', 'earcons', 'sonic branding', 'interaction sounds', 'feedback sounds', 'app audio', 'satisfying sounds'. NOT for professional audio engineering (use sound-engineer), Windows 3.1 retro sounds specifically (use win31-audio-design), music composition (use sound-engineer).

日本語の概要は準備中です。原文の説明を表示しています。

Expert API designer for REST, GraphQL, gRPC architectures. Activate on: API design, REST API, GraphQL schema, gRPC service, OpenAPI, Swagger, API versioning, endpoint design, rate limiting, OAuth flow. NOT for: database schema (use data-pipeline-engineer), frontend consumption (use web-design-expert), deployment (use devops-automator).

日本語の概要は準備中です。原文の説明を表示しています。

Designs digital experiences for ADHD brains using neuroscience research and UX principles. Expert in reducing cognitive load, time blindness solutions, dopamine-driven engagement, and compassionate design patterns. Activate on 'ADHD design', 'cognitive load', 'accessibility', 'neurodivergent UX', 'time blindness', 'dopamine-driven', 'executive function'. NOT for general accessibility (WCAG only), neurotypical UX design, or simple UI styling without ADHD context.

日本語の概要は準備中です。原文の説明を表示しています。

Design UI components/design systems, review visual design, check accessibility. Triggers: design system, color palette, font pairing, WCAG check. Data-driven: palettes, fonts, UX guidelines.

日本語の概要は準備中です。原文の説明を表示しています。

Use when designing UI components, reviewing visual design, building design systems, or checking accessibility. Auto-activates on frontend design tasks and UI reviews.

日本語の概要は準備中です。原文の説明を表示しています。

Develop, challenge, and document Chisel processor microarchitecture designs before implementation. Use when discussing or writing design documents for processor pipelines, queues, issue logic, rename, ROB, LSU, caches, MSHRs, forwarding, wakeup, replay, flush, privilege, exceptions, or other cycle-accurate hardware mechanisms; when converting design conversations into stable Markdown specifications; or when reviewing a proposed Chisel CPU design for correctness, timing, area, verification cost, and cross-document consistency.

日本語の概要は準備中です。原文の説明を表示しています。

Check a prototype against its original design direction and requirements before shipping. Compares implementation to the mockup/spec/context, flags drift in layout, spacing, type, color, states, and behavior, and reports a pass/fix list. Use when the user says "design QA", "does it match the design", "check against the spec", "conformance check", or before sharing/handing off a prototype. Part of the Product Design set. Uses a browser tool for visual comparison.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2/PE3/PE3b/PEmax variants, MOSAIC in situ saturation mutagenesis, the PRIME pooled-screen methodology (Ren 2023; ~3,699 ClinVar variant screens), chromatin context as a major locus-level determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

日本語の概要は準備中です。原文の説明を表示しています。

Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose monogenic and syndromic obesity in children and adolescents using a structured step-by-step algorithm. Use this skill whenever a clinician suspects a genetic cause of obesity, asks about leptin deficiency, MC4R mutation, POMC deficiency, PCSK1 deficiency, leptin receptor deficiency, Bardet-Biedl syndrome, Prader-Willi syndrome, Alström syndrome, or any case of early-onset severe obesity with hyperphagia. Also trigger for questions about targeted pharmacotherapy including setmelanotide or metreleptin, or when to order a genomic obesity panel. Cross-references the NHS Genomic Test Finder skill to surface the relevant R-code once a diagnosis is reached.

日本語の概要は準備中です。原文の説明を表示しています。

Guide a non-stigmatising pediatric obesity consultation using the 5As framework (Ask, Assess, Advise, Agree, Assist) and 4Ms assessment (Metabolic, Mechanical, Mental Health, Social Milieu), based on the CMAJ 2025 guideline. Trigger when a clinician asks how to approach a weight conversation with a child or family, how to use the 5As for obesity, how to assess a child with obesity, or how to conduct a non-judgmental obesity visit.

日本語の概要は準備中です。原文の説明を表示しています。

Select the right treatment tier for a child with obesity — behavioural, pharmacologic, or surgical — using the CMAJ 2025 pediatric obesity guideline. Trigger when a clinician asks what to do for a child with obesity, which intervention to start, whether to escalate treatment, or when to consider medication or surgery for pediatric obesity.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user asks to design a multi-agent system, pick an orchestration pattern (supervisor/swarm/pipeline), generate tool schemas for agents, or evaluate agent execution logs for cost, latency, and failure bottlenecks. Examples: 'design an agent architecture for research automation', 'generate Anthropic tool schemas from these tool descriptions', 'analyze these agent run logs for bottlenecks'. NOT for Claude Code workflow files (use workflow-builder) or single-agent prompt design (use agent-workflow-designer).

日本語の概要は準備中です。原文の説明を表示しています。

Harvests a DESIGN.md from an existing codebase, critiques it against the actual code, and applies safe quick-win fixes. Three modes harvest / critique / fix. Shells out to `npx @google/design.md lint` for structural validation; never reimplements Google's linter. The on-ramp that makes DESIGN.md adoptable for every existing repo, not just greenfield projects.

日本語の概要は準備中です。原文の説明を表示しています。

全栈设计规划：分级门控管理 DESIGN.md 与 DESIGN-CHANGELOG，内置可检索设计规则库（UX 规则/配色/字体），三层 Token、forge-design-lab 工作台门禁（布局/比例/密度在真 token 骨架上定，Image 2 退为气质稿）、反 AI 模板检测。 触发方式：用户说"设计"、"forge-design"、"先看效果图"，或 forge-dev 调度、需要创建/更新设计文档时。

日本語の概要は準備中です。原文の説明を表示しています。

Expert-level VLSI design covering CMOS logic, custom layout, standard cell design, physical design flow, DRC, LVS, and advanced process nodes.

日本語の概要は準備中です。原文の説明を表示しています。

Expert-level statistics knowledge. Use when working with probability distributions, hypothesis testing, regression, Bayesian statistics, statistical inference, experimental design, ANOVA, or statistical modeling. Also use when the user mentions 'p-value', 'confidence interval', 'hypothesis test', 'regression', 'ANOVA', 'chi-square', 't-test', 'Bayesian', 'maximum likelihood', 'statistical significance', 'correlation', 'normal distribution', or 'sampling distribution'.

日本語の概要は準備中です。原文の説明を表示しています。

Review a written plan or design doc through a designer's lens before implementation - seven passes over information architecture, interaction states, emotional arc, AI-slop risk, design-system alignment, responsive and accessibility coverage, and unresolved decisions. Each dimension is rated 0-10 with an explicit statement of what would make it a 10, then the plan is edited to get there. Use when a plan has a UI surface and you want the design gaps closed before code is written. Not for auditing a live site.

日本語の概要は準備中です。原文の説明を表示しています。

Design and review intuitive, scalable, maintainable HTTP APIs. Use this skill whenever the user wants to design a new REST API, review an existing API or spec, write OpenAPI 3.x definitions, or work with HTTP semantics (GET/POST/PUT/PATCH/DELETE), status codes, idempotency (Idempotency-Key), error envelopes (RFC 7807 problem+json), pagination, filtering, versioning, or API auth (API keys, OAuth2 client credentials, rate limits). Also trigger for "API design", "RESTful", "endpoints", "OpenAPI", "Swagger", "ReDoc", "contract testing", or GraphQL and gRPC design questions.

日本語の概要は準備中です。原文の説明を表示しています。