Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
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Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
日本語の概要は準備中です。原文の説明を表示しています。
This skill provides AWS cost optimization, monitoring, and operational best practices with integrated MCP servers for billing analysis, cost estimation, observability, and security assessment.
日本語の概要は準備中です。原文の説明を表示しています。
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for downstream differential analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
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Unified analysis pipeline for affinity-based proteomics platforms — Olink (PEA, NPX) and SomaLogic SomaScan (SOMAmer, RFU). Platform-aware QC, normalisation, differential abundance, volcano plots, heatmaps, and PCA.
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This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
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Automated cell behavior analysis from microscopy or XR lab recordings. Classifies cell motion phenotypes (migration, proliferation, apoptosis, division, quiescence), computes population-level quantitative metrics (growth rate, migration velocity, directionality index), and emits structured JSON for downstream reporting, plotting, or ELN integration.
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Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.
日本語の概要は準備中です。原文の説明を表示しています。
Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.
日本語の概要は準備中です。原文の説明を表示しています。
This skill calculates key financial ratios and metrics from financial statement data for investment analysis
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This skill provides a way to retrieve information from the AgentScope library for analysis and decision-making.
日本語の概要は準備中です。原文の説明を表示しています。
Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.
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Draft a Root Cause Analysis for an incident, outage, or repeated test failure. Unlike intake/spec/brd, RCA is not a workflow phase — it's a standalone postmortem artifact that often precedes a bugfix intake. Output lives at `docs/rca/<slug>.md`.
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PM-mode brainstorm helper. Captures the requirement via Socratic dialogue before any entry phase (`/intake`, `/spec`, `/tdd`) drafts its artifact. Stage 0 skip-check, Stage 1 gap-analysis, Stage 2 probe-loop, Stage 3 confirm-and-persist. Output lives at `docs/brief/<slug>.md`. Never proposes solutions — Stage 2 dialogue discipline is structurally enforced via `discipline.mjs`.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze NFT projects for investment decisions — evaluate fundamentals, identify red flags, assess risk, and provide buy/hold/avoid recommendations
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Passive domain reconnaissance using Python stdlib. Use this skill for subdomain discovery, SSL certificate inspection, WHOIS lookups, DNS records, domain availability checks, and bulk multi-domain analysis. No API keys required. Triggers on requests like "find subdomains", "check ssl cert", "whois lookup", "is this domain available", "bulk check these domains".
日本語の概要は準備中です。原文の説明を表示しています。
Azure AI Text Analytics SDK for sentiment analysis, entity recognition, key phrases, language detection, PII, and healthcare NLP. Use for natural language processing on text.
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Comprehensive AWS cost analysis and optimization recommendations using AWS CLI and Cost Explorer
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Build anomaly detection applications with Azure AI Anomaly Detector SDK for Java. Use when implementing univariate/multivariate anomaly detection, time-series analysis, or AI-powered monitoring.
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Enables ultra-granular, line-by-line code analysis to build deep architectural context before vulnerability or bug finding.
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Expert security auditor for AI Skills and Bundles. Performs non-intrusive static analysis to identify malicious patterns, data leaks, system stability risks, and obfuscated payloads across Windows, macOS, Linux/Unix, and Mobile (Android/iOS).
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Astropy is the core Python package for astronomy, providing essential functionality for astronomical research and data analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Build document analysis applications using the Azure AI Document Intelligence SDK for Java.
日本語の概要は準備中です。原文の説明を表示しています。