「net」の検索結果

Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. Use when the user asks about non-coding variant effects, pathogenicity, clinical significance, disease associations, functional effects, gene expression changes, splicing disruption, or regulatory effects in promoters and enhancers. Also use for resolving biological terms to tissue/cell-type ontologies (UBERON/CL) or analyzing variants in chr:pos:ref>alt format.

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Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.

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Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).

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GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.

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Playwright automation, Chrome DevTools debugging, and browser interaction testing. Use for E2E/unit tests, capturing screenshots, inspecting network/console logs, or validating user flows in web applications.

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Microsoft docs lookup, code samples, and SDK reference for Azure, .NET, Microsoft 365, Windows, and Power Platform via Microsoft Learn MCP. Use for API reference or official MS documentation retrieval.

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Generate .excalidraw diagrams from natural language. Use when creating flowcharts, mind maps, system architecture diagrams, sequence diagrams, ER diagrams, network diagrams, or any visual process visualization.

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Cloud Engineer IA — Expert en infrastructure cloud (AWS, GCP, Azure, Terraform, K8s, serverless). Conçoit et déploie des architectures cloud natives.

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Expert en création de cabinet de conseil (positioning, proposals, deliverables, pricing, scaling)

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Bulk-create hundreds of AI agent skills for the Agency Roster repo — naming, conflict resolution, batch delegation, GitHub sync, and monetization prep.

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Docker, Kubernetes, container orchestration, and cloud-native deployment for data applications

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Establish build performance baselines and apply systematic optimization techniques. Only activate in MSBuild/.NET build context. USE FOR: diagnosing slow builds, establishing before/after measurements (cold, warm, no-op scenarios), applying optimization strategies like MSBuild Server, static graph builds, artifacts output, and dependency graph trimming. Start here before diving into build-perf-diagnostics, incremental-build, or build-parallelism. DO NOT USE FOR: non-MSBuild build systems, detailed bottleneck analysis (use build-perf-diagnostics after baselining).

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Guide for organizing MSBuild infrastructure with Directory.Build.props, Directory.Build.targets, Directory.Packages.props, and Directory.Build.rsp. Only activate in MSBuild/.NET build context. USE FOR: structuring multi-project repos, centralizing build settings, implementing NuGet Central Package Management (CPM) with ManagePackageVersionsCentrally, consolidating duplicated properties across .csproj files, setting up multi-level Directory.Build hierarchy with GetPathOfFileAbove, understanding evaluation order (Directory.Build.props → SDK .props → .csproj → SDK .targets → Directory.Build.targets). Critical pitfall: $(TargetFramework) conditions in .props silently fail for single-targeting projects — must use .targets. DO NOT USE FOR: non-MSBuild build systems, migrating legacy projects to SDK-style (use msbuild-modernization), single-project solutions with no shared settings. INVOKES: no tools — pure knowledge skill.

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Guide for MSBuild extensibility: CustomBefore/CustomAfter hooks, wildcard imports with alphabetic ordering, import gating with control properties, NuGet package build extension layout (build/buildTransitive), and the MicrosoftCommonPropsHasBeenImported guard. Only activate in MSBuild/.NET build context. USE FOR: diagnosing and fixing MSBuild import and hook patterns, reviewing and fixing extension point anti-patterns in Directory.Build files, fixing missing Exists() guards on imports that break fresh clones, fixing NuGet package hooks being silently dropped instead of appended, making build targets extensible for other projects, injecting custom logic into the build pipeline, creating NuGet packages that extend the build, conditionally disabling imports. DO NOT USE FOR: target authoring patterns (use target-authoring), props vs targets placement (use directory-build-organization), general anti-patterns (use msbuild-antipatterns), non-MSBuild build systems.

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Fix MSBuild targets that generate files during the build but those files are missing from compilation or output. Only activate in MSBuild/.NET build context. USE FOR: generated source files not compiling (CS0246 for a type that should exist), custom build tasks that create files but they are invisible to subsequent targets, globs not capturing build-generated files because they expand at evaluation time before execution creates them, ensuring generated files are cleaned by the Clean target. Covers correct BeforeTargets timing (CoreCompile, BeforeBuild, AssignTargetPaths), adding to Compile/FileWrites item groups, using $(IntermediateOutputPath) instead of hardcoded obj/ paths. DO NOT USE FOR: C# source generators that already work via the Roslyn pipeline, T4 design-time generation that runs in Visual Studio, non-MSBuild build systems. INVOKES: no tools — pure knowledge skill.

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Patterns for managing MSBuild item groups: Include/Remove/Update semantics, item metadata, batching with %(Metadata), transforms, per-item filtering, and cross-product batching pitfalls. Only activate in MSBuild/.NET build context. USE FOR: diagnosing and fixing item group anti-patterns in .csproj files, reviewing item management for correctness, fixing CS2002 duplicate file warnings from SDK globbing, fixing targets that run more times than expected due to cross-product batching, fixing Include vs Update misuse on SDK-globbed items, fixing FileWrites registration for generated file clean support, moving generated files to IntermediateOutputPath. DO NOT USE FOR: target chain architecture (use target-authoring), property patterns (use property-patterns), incrementality (use incremental-build), general anti-patterns (use msbuild-antipatterns), non-MSBuild build systems.

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Catalog of MSBuild anti-patterns with detection rules and fix recipes. Only activate in MSBuild/.NET build context. USE FOR: reviewing, auditing, or cleaning up .csproj, .vbproj, .fsproj, .props, .targets, or .proj files. Each anti-pattern has a symptom, explanation, and concrete BAD→GOOD transformation. Covers Exec-instead-of-built-in-task, unquoted conditions, hardcoded paths, restating SDK defaults, scattered package versions, and more. DO NOT USE FOR: non-MSBuild build systems (npm, Maven, CMake, etc.), project migration to SDK-style (use msbuild-modernization).

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Guide for using MSBuild Server to improve CLI build performance. Only activate in MSBuild/.NET build context. Activate when developers report slow incremental builds from the command line, or when CLI builds are noticeably slower than IDE builds. Covers MSBUILDUSESERVER=1 environment variable for persistent server-based caching. Do not activate for IDE-based builds (Visual Studio already uses a long-lived process).

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MSBuild property definition patterns: conditional defaults, composition/concatenation, path normalization, trailing slash handling, TFM detection helpers, and property evaluation order. Only activate in MSBuild/.NET build context. USE FOR: diagnosing and fixing MSBuild property definition issues in .props or .csproj files, reviewing and fixing shared property configuration anti-patterns, fixing DefineConstants or NoWarn being overwritten instead of appended, fixing unconditional property assignments that prevent project-level overrides, fixing unquoted conditions that fail when properties are empty, fixing hardcoded paths that break cross-platform builds, setting property defaults that can be overridden, understanding property evaluation order and last-write-wins semantics. DO NOT USE FOR: props vs targets placement (use directory-build-organization), item operations (use item-management), target structure (use target-authoring), general anti-patterns (use msbuild-antipatterns), non-MSBuild build systems.

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Guide for interpreting ResolveProjectReferences time in MSBuild performance summaries. Only activate in MSBuild/.NET build context. Activate when ResolveProjectReferences appears as the most expensive target and developers are trying to optimize it directly. Explains that the reported time includes wait time for dependent project builds and is misleading. Guides users to focus on task self-time instead. Do not activate for general build performance -- use build-perf-diagnostics instead.

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Canonical patterns for writing custom MSBuild targets. Only activate in MSBuild/.NET build context. USE FOR: diagnosing and fixing custom target authoring anti-patterns, reviewing MSBuild target definitions for correctness, diagnosing broken SDK target chains across files (e.g., Directory.Build.targets silently redefining SDK targets), fixing targets that replace CompileDependsOn instead of extending it with $(CompileDependsOn), fixing query targets that return stale results due to Outputs vs Returns misuse, fixing missing Inputs/Outputs causing unnecessary rebuilds, fixing missing FileWrites registration. Covers DependsOnTargets vs BeforeTargets vs AfterTargets, the Build→CoreBuild three-level pattern, hooking into the build pipeline, the $(XxxDependsOn) chain-extension pattern. DO NOT USE FOR: incremental build tuning (use incremental-build), parallelization (use build-parallelism), general anti-patterns (use msbuild-antipatterns), non-MSBuild build systems.

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PyTorch, TensorFlow, neural networks, CNNs, transformers, and deep learning for production

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Scaffolds new agent skills for the dotnet/skills repository. Use when creating a new skill, generating SKILL.md files, or setting up skill directory structures. Handles frontmatter generation, section templates, and validation guidance.

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Scaffolds eval.yaml test files for agent skills in the dotnet/skills repository. Use when creating skill tests, writing evaluation scenarios, defining assertions and rubrics, or setting up test fixture files. Handles eval.yaml generation, fixture organization, and overfitting avoidance. Do not use for running or debugging existing tests nor for skills authoring.

日本語の概要は準備中です。原文の説明を表示しています。