「sca」の検索結果

Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.

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Designs QC, corrects signal drift, removes batch effects, filters features, normalizes samples, and imputes missing values for untargeted LC-MS/GC-MS metabolomics, framing each step as a measurement model that can create or erase biological signal. Use when processing a peak/feature table before statistical analysis, choosing a drift-correction or sample-normalization method, deciding QC RSD vs D-ratio filtering, or handling left-censored missing values. The feature table is produced by metabolomics/xcms-preprocessing or metabolomics/msdial-preprocessing; transformation/scaling for modeling defers to metabolomics/statistical-analysis; cross-study design issues link to experimental-design/batch-design.

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Designs and analyzes stable-isotope-resolved metabolomics (SIRM / isotope tracing / fluxomics) experiments that measure metabolic ACTIVITY via 13C/15N/2H tracers, distinct from steady-state pool profiling. Covers tracer choice, isotopologue vs isotopomer, mass-isotopomer distributions (MID), fractional enrichment, the mandatory natural-abundance + tracer-purity correction (IsoCor, AccuCor), and the metabolic/isotopic steady-state vs non-stationary (INST-MFA) distinction. Use when feeding a labeled tracer and interpreting labeling patterns, correcting raw isotopologue intensities, computing or plotting an MID, or deciding tracing vs abundance profiling. For absolute pool concentration and MRM mechanics see metabolomics/targeted-analysis; for constraint-based genome-scale flux (FBA, not empirical tracing) see systems-biology/flux-balance-analysis; for feature detection see metabolomics/xcms-preprocessing; for pathway enrichment that ignores the pool-vs-flux caveat see metabolomics/pathway-mapping.

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Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

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Performs molecular similarity searching using Tanimoto, Tversky, Dice, and cosine coefficients on bit/count fingerprints with explicit choice rules for symmetric vs asymmetric measures, scaffold-hopping vs lead-optimization regimes, activity-cliff diagnosis, and large-library nearest-neighbor methods (BulkTanimoto, Annoy MHFP6, USRCAT). Use when ranking compounds by structural resemblance to a query, clustering libraries, finding analogs, or diagnosing activity cliffs.

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Analyze the competitive landscape for an SCF submission. Identifies similar projects on Stellar and other chains, assesses overlap and differentiation. Use when reviewing or drafting an SCF submission and you need to map similar projects on Stellar and other chains and articulate the differentiation.

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React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

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Writes work-in-progress code and tests based on design doc

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Continues Charted Coding work for a PR by routing to scaffold, red, or green based on design doc progress. Use when resuming work on a PR, continuing TDD after a break, or when the user invokes charted continue with a design doc and PR number.

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Structured bug diagnosis and fixing workflow — reproduce, diagnose root cause, apply minimal fix, write regression test, and scan for similar patterns

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When the user wants to audit, review, or diagnose SEO issues on their site. Also use when the user mentions "SEO audit," "technical SEO," "why am I not ranking," "SEO issues," "on-page SEO," "meta tags review," or "SEO health check." For building pages at scale to target keywords, see programmatic-seo. For adding structured data, see schema-markup.

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Build AI content generation systems at scale. TRIGGERS - Use when user needs help with ai-content-generation-system related tasks.

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Build AI batch processing systems for scale. TRIGGERS - Use when user needs help with ai-batch-processor related tasks.

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Plan transition from freelancer to agency with scaling. TRIGGERS - Use when user needs help with agency-builder related tasks.

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Transform images with resize, crop, smart crop, upscale, remove background, and 20+ operations.

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Extract parties, premises, lease term, rent, escalation, deposit, options, and expense obligations from commercial leases.

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Imports FBX meshes into CARLA on UE 5.8 as spawnable props — drives the editor headlessly to import the mesh, derives the prop size from its measured bounds, and registers it in PropParameters.json so it appears in the blueprint library as static.prop.<name>. Handles the FBX unit-scale problem, verifies the result against a running server, and can revert cleanly. Use when the user asks to "import a prop", "add a custom mesh/object to CARLA", "make my model spawnable", or a prop imports but never shows up in the blueprint library.

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Listens to a CARLA sensor and either saves its data to files, shows it live in a window, prints a one-shot summary, or (ros-info) reports the native ROS 2 topics, QoS and enabled-for-ROS state so you can echo it from ROS instead. Cameras save as PNG (depth/semantic auto-colourised) and display in a pygame window; lidar saves as .ply and shows as a top-down scatter; IMU/GNSS/radar/collision stream to JSONL or the console. Use when the user asks to "show/view the camera", "display the lidar", "save the sensor data / capture a dataset", or "what is this sensor reading". Select the sensor by id, type, or the actor it's attached to.

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Spawns vehicles on a running CARLA server and destroys them — scattered across the map's spawn points on Traffic Manager autopilot, a row queued in a single lane at a fixed spacing, or a single hero/ego vehicle (optionally named for native ROS 2 publishing with --ros-name). Covers blueprint filtering, the atomic autopilot hand-off, and cleanup. Use when the user asks to "spawn vehicles/cars/traffic", "add N cars driving around", "put cars in a lane 15 m apart", "spawn the ego/hero vehicle", or "remove the vehicles".

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Expert database administrator specializing in high-availability systems, performance optimization, and disaster recovery. Masters PostgreSQL, MySQL, MongoDB, and Redis with focus on reliability, scalability, and operational excellence.

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Expert Django developer mastering Django 4+ with modern Python practices. Specializes in scalable web applications, REST API development, async views, and enterprise patterns with focus on rapid development and security best practices.

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Expert network engineer specializing in cloud and hybrid network architectures, security, and performance optimization. Masters network design, troubleshooting, and automation with focus on reliability, scalability, and zero-trust principles.

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Expert fintech engineer specializing in financial systems, regulatory compliance, and secure transaction processing. Masters banking integrations, payment systems, and building scalable financial technology that meets stringent regulatory requirements.

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Expert Kubernetes specialist mastering container orchestration, cluster management, and cloud-native architectures. Specializes in production-grade deployments, security hardening, and performance optimization with focus on scalability and reliability.

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