Performs differential expression on bulk RNA-seq count data with DESeq2's negative-binomial GLM, Wald and LRT testing, apeglm/ashr/normal LFC shrinkage, independent filtering, Cook's outlier handling, VST/rlog transforms, and design formulas including paired, batch, and interaction terms. Use when running bulk DE, choosing DESeq2 over edgeR or limma-voom, building a paired or interaction design, applying LFC shrinkage for ranking or GSEA, choosing Wald vs LRT, troubleshooting padj=NA, picking VST vs rlog, importing salmon/kallisto via tximport, or analyzing prokaryotic RNA-seq.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Queries myvariant.info BioThings aggregator for ClinVar, gnomAD, dbSNP, dbNSFP, COSMIC, CADD, and CIViC annotations in batched, version-tracked requests. Use when annotating variant lists from multiple databases simultaneously without managing per-source APIs, and when reproducibility-grade analyses require recording source data versions via _meta.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract) with SES scaling, k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Identify differentially accessible chromatin regions across conditions using DiffBind, csaw, DESeq2, or edgeR. Use when comparing ATAC-seq accessibility between treatment groups, choosing between consensus-peak vs sliding-window approaches, picking the correct normalization (full library vs reads-in-peaks), correcting batch with SVA/RUVseq, or interpreting log2FC and FDR thresholds in a chromatin context.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Prove the next page of a list, or the next batch of an infinite scroll, loads NEW rows from the server, repeats none, and that the end of the list is handled. Use when pagination or infinite scroll was added or changed, when a list shows the same rows twice or skips some, or when the last page still offers a next control.
日本語の概要は準備中です。原文の説明を表示しています。
reticlehq/reticle☆ 1,2182026年10月14日 更新
Access Core Motion accelerometer, gyroscope, magnetometer, device-motion, pedometer, activity-recognition, altitude, headphone motion, batched high-frequency workout motion, and water-submersion/depth data. Use when reading device sensors, counting steps, detecting walking/running/driving/cycling, tracking altitude, building motion interactions, handling AirPods head tracking, or implementing watchOS dive/depth features.
日本語の概要は準備中です。原文の説明を表示しています。
dpearson2699/swift-ios-skills☆ 1,1952026年8月1日 更新
Guides Metronome usage-based billing integration decisions — event ingestion (single and batch, idempotency, billable metrics), contract design (rate cards, overrides, dimensional pricing, products), invoicing lifecycle (grace periods, finalization, Stripe sync), credit and commit management (prepaid, postpaid, thresholds, auto-recharge), and Stripe integration (arrears invoicing, tax providers, line item limits). Use when building, modifying, or reviewing any Metronome integration — including ingesting usage events, creating customers, contracts, or rate cards, designing billable metric group keys, managing credits and commits, configuring invoicing, syncing invoices with Stripe Billing, billing AI applications for token usage, setting up self-serve (PLG) pricing, reviewing customer health, commit burn, portfolios, or renewals, or migrating from Stripe Billing Meters to Metronome.
日本語の概要は準備中です。原文の説明を表示しています。
fcakyon/claude-codex-settings☆ 1,1762026年10月13日 更新
Extract features from 1D signals using signalTimeFeatureExtractor, signalFrequencyFeatureExtractor, and signalTimeFrequencyFeatureExtractor. Use when computing time-domain features (amplitude, energy, shape factors), frequency-domain features (spectral location, power, bandwidth, PSD), or time-frequency features (spectral shape, instantaneous, ridges, wavelet, EMD-derived) on a per-frame basis. Use when the user asks to "extract features", "compute spectral features", "build a feature table for a classifier", "get per-frame statistics", "run feature extraction on this signal", or describes a vibration / biosignal / radar / sensor signal needing features for downstream ML or analysis. Includes optional GPU acceleration via canUseGPU and gpuArray. Does not cover filter design, audio-specific feature extraction (use audioFeatureExtractor in Audio Toolbox instead), batch dataset orchestration, or 2D / image features.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1662026年10月9日 更新
Discover OPC UA servers, connect MATLAB clients, and browse/navigate server nodes using opcuaserverinfo, the Local Discovery Service (LDS), opcua, connect, setSecurityModel, certificate-trust functions, findNodeById, opcuanode, and Namespace/Children traversal. Use when finding OPC UA servers on the network, querying endpoints and security policies, connecting to a server, authenticating with username/password or certificates, configuring security modes, handling certificate-trust or hostname-mismatch errors, troubleshooting failed connections or empty discovery, inspecting an OPC UA certificate (.der/.pem), browsing an address space, finding nodes by name or NodeId, navigating node hierarchies, invoking method nodes, or batch-processing large namespaces. Trigger on: opcuaserverinfo, LDS, opcua, opc.ua.Client, setSecurityModel, opc.ua.trustServerCertificate, OPC UA certificate, findNodeById, opcuanode, browse OPC UA, find node, OPC UA namespace, OPC UA method node, Industrial Communication Toolbox.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1662026年10月9日 更新
Store, retrieve, and pass credentials securely in MATLAB using the built-in MATLAB Vault (setSecret, getSecret, importSecrets, secretID) instead of hardcoding. Handles connections to any authenticated service: REST APIs, databases, cloud storage (S3/Azure/GCS), SFTP, and others. Covers API keys, tokens, passwords, SSH passphrases, CI/batch/scheduled jobs, and "keep credentials out of code" requests. Does NOT cover third-party secret managers (HashiCorp Vault, AWS Secrets Manager), OS-level key management, or the connection/query logic itself.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1662026年10月9日 更新
PDN DC voltage/current analysis, IR drop, design rule checking, and multi-net batch analysis on imported PCB layouts. TRIGGER: user asks about power integrity, PDN analysis, IR drop, voltage distribution, current density, power nets, or design rule checking on a PCB. Invoke BEFORE writing code — the PDN API chain is specialized and non-obvious. SKIP: importing a PCB file (use matlab-read-pcb-layout), EM field/S-parameter extraction (use matlab-analyze-em), material/stackup setup only (use matlab-manage-pcb-material), transmission line design (use matlab-design-pcb-transmission-line).
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1662026年10月9日 更新
Deploy and manage vLLM for high-throughput LLM inference. Configure continuous batching, tensor parallelism, quantization, and OpenAI-compatible API endpoints for production LLM serving.
日本語の概要は準備中です。原文の説明を表示しています。
BagelHole/DevOps-Security-Agent-Skills☆ 1,1602026年5月22日 更新
Orchestrate AI/ML pipelines for data ingestion, model training, batch inference, and RAG indexing using Prefect, Airflow, or Dagster. Build reliable, observable, and retriable workflows for production AI systems.
日本語の概要は準備中です。原文の説明を表示しています。
BagelHole/DevOps-Security-Agent-Skills☆ 1,1602026年5月22日 更新
Reduce LLM API and infrastructure costs through model selection, prompt caching, batching, caching, quantization, and self-hosting strategies. Track spend by team and model, set budgets, and implement cost-aware routing.
日本語の概要は準備中です。原文の説明を表示しています。
BagelHole/DevOps-Security-Agent-Skills☆ 1,1602026年5月22日 更新
Amazon profit margin calculator for sellers. Calculate cost breakdowns, profit margins, break-even points, and get pricing recommendations. Supports single product analysis and batch calculations. Input product cost, shipping, FBA fees, and get instant profitability analysis. No API key required. Use when: (1) evaluating new product profitability before sourcing, (2) diagnosing existing product margins, (3) adjusting pricing strategy, (4) analyzing multiple SKUs at once.
日本語の概要は準備中です。原文の説明を表示しています。
nexscope-ai/eCommerce-Skills☆ 1,1432026年8月26日 更新
Periodically analyze open pull requests for CI failures, code review feedback, and quality issues, then fix them in batch. Use this skill when the user asks to check PR status, triage CI failures, fix review comments, analyze open PRs, or run a scheduled PR health check across the repository.
日本語の概要は準備中です。原文の説明を表示しています。
TencentCloudBase/CloudBase-AI-Toolkit☆ 1,1362026年10月13日 更新
CloudBase CLI (tcb, 云开发CLI, Tencent CloudBase命令行) resource management skill. Use when deploying cloud functions, CloudRun, storage, NoSQL/MySQL, static hosting, permissions, CORS/domains via tcb; for CI/CD and batch ops; when the user prefers CLI; or as the first-session fallback when CloudBase MCP tools are not loaded yet (after install/config, before IDE restart). Covers tcb login (device code for Tencent Cloud accounts; --cloudbase-api-key -e for environment API Key without an account; --apiKeyId/--apiKey for CI) and domain commands (fn/hosting/cloudrun/…) as MCP auth/manage parity — do not default to tcb deploy.
日本語の概要は準備中です。原文の説明を表示しています。
TencentCloudBase/CloudBase-AI-Toolkit☆ 1,1362026年10月13日 更新
Generate database seed scripts with realistic sample data. Reads Drizzle schemas or SQL migrations, respects foreign key ordering, produces idempotent TypeScript or SQL seed files. Handles D1 batch limits, unique constraints, and domain-appropriate data. Use when populating dev/demo/test databases. Triggers: 'seed database', 'seed data', 'sample data', 'populate database', 'db seed', 'test data', 'demo data', 'generate fixtures'.
日本語の概要は準備中です。原文の説明を表示しています。
jezweb/claude-skills☆ 1,0622026年10月9日 更新
Generate AI images using Gemini or GPT APIs directly. Covers model selection (Gemini for scenes; GPT Image 2 for text rendering, batch variations, multi-reference compositing; GPT Image 1.5 for transparent icons), the 5-part prompting framework, API calling patterns, multi-turn editing, and quality assurance. Produces photorealistic scenes, icons, illustrations, OG images, posters, infographics, and product shots. Use when building websites that need images, creating marketing assets, or generating visual content. Triggers: 'generate image', 'ai image', 'create hero image', 'make an icon', 'generate illustration', 'create og image', 'poster', 'infographic', 'image variations', 'gpt-image-2', 'ai art', 'image generation'.
日本語の概要は準備中です。原文の説明を表示しています。
jezweb/claude-skills☆ 1,0622026年10月9日 更新
Build Google Apps Script automation for Sheets and Workspace. Custom menus, triggers (onEdit / time-driven / form submit), dialogs, sidebars, email batches, PDF export, external API. Use whenever the user wants to automate a Google Sheet, build a Sheets menu / sidebar / dialog, hit a Sheets row from email or a webhook, schedule a Sheets workflow, or asks 'how do I script this in Sheets'.
日本語の概要は準備中です。原文の説明を表示しています。
jezweb/claude-skills☆ 1,0622026年10月9日 更新
Python typing exclusion worker: remove assigned mypy exclusion modules in small scoped batches, fix typing issues, run validation, and produce a structured completion summary. Use when running parallel typing-debt workers or when asked to remove modules from pyproject mypy exclusion overrides.
日本語の概要は準備中です。原文の説明を表示しています。
getsentry/skills☆ 1,0492026年10月13日 更新
Blender to web export workflows for 3D models and animations. Use this skill when exporting Blender models to glTF for web, optimizing 3D assets for Three.js or Babylon.js, batch processing models with Python scripts, automating Blender workflows, or creating web-ready 3D pipelines. Triggers on tasks involving Blender glTF export, bpy scripting, 3D asset optimization, model compression, texture baking, or Blender automation. Exports models for threejs-webgl, react-three-fiber, and babylonjs-engine skills.
日本語の概要は準備中です。原文の説明を表示しています。
freshtechbro/claudedesignskills☆ 1,0482025年11月20日 更新