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概要と使いどころ
Draft cold emails, warm intro blurbs, follow-ups, update emails, and investor communications for fundraising. Use when the user wants outreach to angels, VCs, strategic investors, or accelerators and needs concise, personalized, investor-facing messaging.
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Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). ...
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Generates complete two-sample Mendelian randomization research designs from a user-provided outcome, exposure or exposure family, and robustness direction. Use when a study centers on summary-statistics causal inference with instrument selection, harmonization, IVW-primary estimation, complementary estimators, sensitivity analyses, optional multivariable upgrades, and conservative evidence interpretation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
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Generates complete FAERS pharmacovigilance study designs for one-drug whole-profile safety mapping using signal detection, subgroup analysis, onset/seriousness characterization, and conservative label-gap interpretation.
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Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.
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Generates complete FAERS pharmacovigilance study designs for multi-drug or class-level safety comparison inside one predefined SOC or AE family using active comparators, disproportionality analysis, subgroup characterization, and reviewer-facing evidence control.
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Evidence-based medical knowledge and research mentor grounded in the Bian Que tradition. Covers clinical reasoning, diagnostic thinking (望闻问切), pharmacology, pathology, differential diagnosis, medical literature appraisal, and the philosophy of early intervention. Trigger whenever users ask about medicine, clinical science, drugs, disease mechanisms, diagnosis, lab interpretation, treatment comparison, or health sciences. Even without explicit research framing, trigger on any topic touching disease, therapeutics, or clinical decision-making. Part of the AIPOCH Medical Research Skill Hub.
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Use when performing correlation analysis between two variables including Pearson and Spearman correlation methods. Supports command-line parameter input, automatic data format detection, parameter validation, result directory creation, and CSV or TXT format result export.
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Use when evaluating stocks through Dan Bin's long-term compounder lens: buy great companies, hold through volatility, and let time do the work. Focus on consumer, pharma, and tech compounders.
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Execute work units through the rigorous 4-phase Metaswarm cycle (Implement -> Validate -> Adversarial Review -> Commit) with independent quality gate enforcement.
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Multi-protocol consensus for agent swarms supporting Raft leader election, Byzantine fault tolerance, Gossip state propagation, and CRDT conflict-free merging.
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Half-hour television comedy craft (半小时情景喜剧/笑点力学/困境机器/多机位单机位格式) — merged from Evan S. Smith's Writing Television Sitcoms (premise-driven comedy in three levels, nine predicaments, six character mixes, setup/punchline mechanics, toppers, running gags, ten comedic nuances, format rules), Neil Landau's sitcom seven-step formula and comedy-room models, Richard Blum's act-length and set-count parameters, Phoebe Waller-Bridge's Fleabag scripts (direct address as a season-long device, six-episode skeleton), Pamela Douglas on dramedy, Kam Miller on complementary comic traits, and Jesse Armstrong on jokes carrying tragedy. Use when writing or fixing a sitcom episode or spec, raising joke density per page, designing a comic predicament that generates stories, choosing between multi-camera and single-camera format and page counts, structuring cold open/acts/tag, writing a half-hour pilot, running a comedy punch-up, or making a drama funny without shifting genre.
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Writing a Succession-style ensemble series (继承之战群像剧写法) — distilled from Jesse Armstrong's complete shooting scripts for all four seasons, 39 episodes (Faber 2023), with his introductions and footnotes, plus Frank Rich's and Lucy Prebble's essays on the writers' room. Covers the invisible-act three-test for scripts with no ACT marks, container episodes built on a ceremony's running order, pressure chambers, one core question per episode, finales with fewer and longer scenes, the absent protagonist at the climax, humiliation passed downward, stage directions carrying subtext and "maybe", reversals turned on one word, writing long, alts, the mega-chart, and engineering an ending once the plot engine loses pressure. Use when the user wants a dynastic family drama, a media-power ensemble, a wedding/funeral/summit set piece, a streaming hour with no act breaks, a finale that redraws alliances, or asks how to "Succession-ize" a script or kill a lead mid-season.
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How episodic television actually gets made by a group (编剧室与制作现实) — merged from Goldberg & Rabkin (pitch as audition, leave-behind, cracking the story, beat sheet, notes discipline, production rewrites), Pamela Douglas (John Wells's room, staff-from-hell mistakes, the seven-rung ladder, step deal, the 14-day draft), Neil Landau's showrunner interviews (Lindelof, Mazzara, Katims, Bays), Evan Smith on sitcom staffing and roundtables, Richard Blum (dated), Kam Miller, and first-hand accounts by David Chase, Jesse Armstrong, Lucy Prebble, Aaron Sorkin, Julian Fellowes and Phoebe Waller-Bridge. Use when joining or running a writers' room, breaking an episode with a group, writing a leave-behind, beat sheet or outline on deadline, pitching episode ideas to an existing series, writing a spec episode, taking or giving notes, rewriting because of money, actors or locations, choosing between a staffed room and a single-author process, or asking 什么是 showrunner／编剧室怎么运作／怎么接 note.
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Render, preview, validate, and burn consistent production subtitles from QC-passed real-timestamp caption artifacts. Use for AI-video production, washed-video production, IndexTTS2 explainers, practical long-form videos, talking-head edits, Kimi-style dark rounded captions, warm-white translucent captions, subtitle styling, subtitle overlays, or fixing caption size, position, shadow, drift, and 4K scaling. Always pair with ra-audio-to-subtitles when final word timestamps do not already exist.
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Create deterministic editorial-style cover images with a warm paper-gray background, oversized black slab-serif/Chinese display typography, generous whitespace, and a dotted vector analysis icon. Use when the user asks for a “点阵编辑风封面”, “暖灰杂志风封面”, “Codex + Hyperframes 同款封面”, or wants to reproduce/adapt the specific minimal left-text/right-icon banner style. Produce editable SVG and a rendered PNG; do not use this skill for generic covers without this visual direction.
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Use when the reflex is to add a feature, layer, or process. Prefer removing harmful or nonessential elements first, with an irreversibility guard before deletion.
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Authors Vally conformance tests for prompts, instructions, agents, and skills, and refuses jailbreak, prompt-injection, harmful-elicitation, TOS, CoC, and PII-extraction stimuli
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Design Thinking method coaching knowledge across all nine methods including per-method techniques, deep expertise, and industry context (energy, financial services, healthcare, manufacturing, nonprofit and social impact, pharmaceuticals and life sciences, professional services, public sector, retail and CPG)
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Routes finance: Bigdata/RavenPack, US fundamentals/yfinance, A-share news/policy, sector Top N/公告, Gangtise/岗底斯 setup. Reads one bundled specialist. Pharma reporting and general argument review keep their own direct entries.
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Write a sincere condolence or sympathy message when someone has died or a friend is grieving — warm, personal, and free of the clichés that hurt more than help. Use when asked what to say when someone dies, write a sympathy/condolence message, my friend lost their [person], or I don't know what to say. Produces a heartfelt message tuned to your relationship and the situation, drawn from a specific memory or quality where possible, an honest acknowledgment (not toxic-positive platitudes), an offer of concrete support, and guidance on what to avoid saying.
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Use when asked 帮我写期末评语, 学生评语, 班主任评语, 综合素质评价评语, 素质报告单评语, or write end-of-term comments for a class in China. Produces individual comments in Chinese, warm and specific to each student, in the second person, built from the teacher's notes: a real strength with an example, one growth area framed as a next step, and encouragement, with no labels, no comparison between students and no repeated stock phrases across the class.
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Set a boundary with someone — a friend, family member, coworker, or partner — clearly and kindly, with the actual words and a plan for the pushback. Use when asked how do I set a boundary with, I need to say no to, someone keeps overstepping, or help me set limits with. Produces a read on the boundary you actually need, a warm-but-firm script to state it (without over-explaining or apologizing it away), how to hold it when they push back or guilt-trip, and what to do if they don't respect it — because a boundary you can't state and hold isn't a boundary.
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Plan a board game night that actually lands — the right games for your group size, mix, and time, in a running order that keeps energy up. Use when asked to plan a game night, what board game should we play, games for [N] people, or what to play with a mixed group. Produces game picks matched to player count and experience, a warm-up-to-main running order, teach-time and play-time estimates, and swaps for the non-gamers or the one player who hates losing.
日本語の概要は準備中です。原文の説明を表示しています。