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概要と使いどころ
Configure this repo for the engineering skills — set up its issue tracker, triage label vocabulary, and domain doc layout. Run once before first use of the other engineering skills.
日本語の概要は準備中です。原文の説明を表示しています。
Required reading before writing any HogQL/SQL or calling execute-sql against PostHog. Use whenever the user wants to search, find, or do complex aggregations PostHog entities (insights, dashboards, cohorts, feature flags, experiments, surveys, hog flows, data warehouse, persons, etc.) and query analytics data (trends, funnels, retention, lifecycle, paths, stickiness, web analytics, error tracking, logs, sessions, LLM traces). Covers HogQL syntax differences from ClickHouse SQL, system table schemas (system.*), available functions, query examples, and the schema-discovery workflow.
日本語の概要は準備中です。原文の説明を表示しています。
Pick the right y-axis unit when creating or updating a TrendsQuery insight via `posthog:insight-create` or `posthog:insight-update`. Use when the agent is about to add a `formula` purely to convert units (e.g. dividing seconds by 60 to display minutes), when a `math_property` is a duration, currency, ratio, or large count, or whenever the user mentions "format the y-axis", "duration", "seconds", "minutes", "hours", "milliseconds", "ms", "percentage", "currency", "decimals", "axis label", or "axis unit" in the context of a graph insight.
日本語の概要は準備中です。原文の説明を表示しています。
Use Cursor's browser aria snapshots to audit a page for accessibility issues — missing labels, broken tab order, contrast, and ARIA misuse.
日本語の概要は準備中です。原文の説明を表示しています。
Diagnostic test / biomarker accuracy — sensitivity, specificity, PPV, NPV, likelihood ratios, accuracy from a 2x2 table; ROC curve, AUC, and the optimal cutoff (Youden) for a continuous biomarker; and post-test probability via Bayes. Use when you have test results vs a gold standard (binary 2x2, or a continuous score + true labels) and need to judge how good the test is, pick a threshold, or compute the probability of disease given a result. Emphasizes the prevalence-dependence of PPV/NPV.
日本語の概要は準備中です。原文の説明を表示しています。
Mendelian randomization (MR) causal inference — does an exposure, risk factor, or biomarker CAUSALLY affect a disease/outcome, using genetic variants as instrumental variables (IEU OpenGWAS / EpiGraphDB MR-EvE). Use this whenever the user asks if X causes Y, whether an observational association is actually causal or just correlation, if a biomarker/trait is a causal risk factor, wants to triangulate epidemiology against genetic evidence, or mentions Mendelian randomization, instrumental-variable analysis, two-sample MR, or genetic causal evidence — even if they never say "MR" (e.g. "is LDL cholesterol actually causal for heart disease?", "does BMI cause type 2 diabetes or just correlate?", "is CRP a causal driver of stroke?"). Covers trait-label resolution, MR effect direction/magnitude, instrument quality (MOE score), method agreement (IVW vs MR-Egger vs weighted median), bidirectional MR for reverse causation, and distinguishing causation from genetic correlation. Not for plain GWAS association lookups (use the GWAS skills) or fitting your own instruments from raw summary statistics.
日本語の概要は準備中です。原文の説明を表示しています。
High-level PyTorch framework with Trainer class, automatic distributed training (DDP/FSDP/DeepSpeed), callbacks system, and minimal boilerplate. Scales from laptop to supercomputer with same code. Use when you want clean training loops with built-in best practices.
日本語の概要は準備中です。原文の説明を表示しています。
Publication-quality physics plots — vector fields, streamlines, contour maps, 3D surfaces, phase space, spectrograms, and animations. Optimized for journal submission with LaTeX labels, proper colormaps, and multi-panel layouts.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluates LLMs across 60+ academic benchmarks (MMLU, HumanEval, GSM8K, TruthfulQA, HellaSwag). Use when benchmarking model quality, comparing models, reporting academic results, or tracking training progress. Industry standard used by EleutherAI, HuggingFace, and major labs. Supports HuggingFace, vLLM, APIs.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluates LLMs across 100+ benchmarks from 18+ harnesses (MMLU, HumanEval, GSM8K, safety, VLM) with multi-backend execution. Use when needing scalable evaluation on local Docker, Slurm HPC, or cloud platforms. NVIDIA's enterprise-grade platform with container-first architecture for reproducible benchmarking.
日本語の概要は準備中です。原文の説明を表示しています。
High-performance vector similarity search engine for RAG and semantic search. Use when building production RAG systems requiring fast nearest neighbor search, hybrid search with filtering, or scalable vector storage with Rust-powered performance.
日本語の概要は準備中です。原文の説明を表示しています。
Runs LLM inference on CPU, Apple Silicon, and consumer GPUs without NVIDIA hardware. Use for edge deployment, M1/M2/M3 Macs, AMD/Intel GPUs, or when CUDA is unavailable. Supports GGUF quantization (1.5-8 bit) for reduced memory and 4-10× speedup vs PyTorch on CPU.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that do not fit in memory.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end CLIP-seq pipeline from FASTQ to ENCODE-compliant binding sites, single-nucleotide crosslink maps, annotation, motifs, and (optionally) differential binding. Use when running the full Yeo lab eCLIP / iCLIP / iCLIP2 / iCLIP3 / irCLIP / PAR-CLIP analysis with SMInput control, protocol-specific UMI extraction, ENCODE STAR parameters, CLIPper or Skipper peak calling with stringent log2 FC and -log10 p thresholds, IDR rescue and self-consistency QC, and downstream motif registration with mCross or PEKA.
日本語の概要は準備中です。原文の説明を表示しています。
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
日本語の概要は準備中です。原文の説明を表示しています。
Drug and chemical toxicity assessment via adverse outcome pathways (AOPs), real-world FAERS adverse event signals, FDA labels, and toxicogenomic associations. Triangulates molecular initiating event to cellular outcome to organ-level toxicity to clinical adverse event. Use for hepatotoxicity/cardiotoxicity/nephrotoxicity prediction and toxicology reports.
日本語の概要は準備中です。原文の説明を表示しています。
Drug safety and adverse event analysis — FAERS spontaneous-report mining, FDA black-box warnings, signal detection (PRR, ROR, IC), risk factors by demographic/comorbidity, and label change tracking. Use for post-market safety surveillance, AE signal investigation, drug-AE association strength scoring, and pharmacovigilance reports.
日本語の概要は準備中です。原文の説明を表示しています。
Find commercial sources for chemical compounds — PubChem/ChEMBL identity resolution then vendor catalog search across ZINC, Enamine, eMolecules, Mcule. Compares pricing, availability, and identifies purchasable analogs when an exact compound is not in stock. Use for chemical procurement, virtual library curation, and 'where can I buy X' questions for synthesis planning.
日本語の概要は準備中です。原文の説明を表示しています。
Drug regulatory and approval research — FDA substance registry, ATC/EPC classification, EMA decisions, generic-drug status, FDA Orange Book exclusivity, NDA/BLA pathways. Use for jurisdiction-aware approval status (FDA vs EMA), generic vs brand availability, exclusivity expiry tracking, and regulatory pathway selection. Always specifies the market when reporting status.
日本語の概要は準備中です。原文の説明を表示しています。
Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
日本語の概要は準備中です。原文の説明を表示しています。
Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.
日本語の概要は準備中です。原文の説明を表示しています。
Designs and validates quantitative targeted metabolomics assays (MRM/SRM on triple-quadrupole, PRM on high-resolution instruments) to report absolute concentrations. Covers the internal-standard strategy (external cal -> global IS -> standard addition -> stable-isotope-labeled IS), weighted calibration judged by back-calculated %RE not R-squared, ion-ratio quantifier/qualifier confirmation, matrix-effect/recovery characterization, and ICH M10 method validation. Use when quantifying a closed panel of known metabolites with units, building or validating an LC-MS/MS assay, choosing an IS or calibration weighting, or judging whether a reported concentration is trustworthy. For untargeted feature detection see metabolomics/xcms-preprocessing; for group statistics see metabolomics/statistical-analysis; for flux/MID/tracing see metabolomics/isotope-tracing.
日本語の概要は準備中です。原文の説明を表示しています。
Meta-skill — browse and discover all installed stellar.new skills. Use when a user says "what skills do I have", "show me available skills", "what can I do", "find a skill for X", "which skill should I use", "help me navigate", "what does stellar.new do", or "where do I start". Lists skills by journey phase, surfaces the SKILL_ROUTER trigger phrases, and recommends the next skill given current context.
日本語の概要は準備中です。原文の説明を表示しています。
Zero-knowledge proofs and privacy patterns on Stellar. Covers Groth16 verification in smart contracts via BLS12-381 host functions (CAP-0059, available), the BN254 + Poseidon proposals (CAP-0074/0075, status-sensitive), and concrete toolchain walkthroughs for Circom (on-chain verifiable today), Noir, and RISC Zero (attestation pattern until BN254 lands). Use when building privacy-preserving applications, ZK-verifier contracts, or wiring a proving toolchain to Stellar.
日本語の概要は準備中です。原文の説明を表示しています。