「dating」の検索結果

Audit agent skills, plugins, prompts, manifests, scripts, dependencies, and bundled assets for provenance, prompt-injection, permission, execution, exfiltration, persistence, and update risk. Use when evaluating a third-party skill before installing, enabling, updating, publishing, or distributing it; reviewing an untrusted SKILL.md, agent configuration, MCP integration, archive, or repository; comparing a package with a known-good version; or investigating unexpected tool, network, credential, or filesystem behavior.

日本語の概要は準備中です。原文の説明を表示しています。

Design reproducible evaluations for AI agents with representative task sets, explicit rubrics, appropriate graders, baselines, regression gates, and failure analysis. Use when defining agent quality, comparing prompts or models, validating a release, measuring tool-use reliability, investigating regressions, or deciding whether an agent is ready for production.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Mathematical Statistician. Use when a task calls for Mathematical Statistician judgment. Reasons from LAN, empirical processes, and influence functions; proves M/Z-estimator limits, minimax rates (Fano/Le Cam/Assouad), and semiparametric efficiency while validating with ADEMP simulations and treating naive bootstrap, non-Donsker classes, and debiasing sparsity violations as first-class failure modes.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Geomorphologist. Use when a task calls for Geomorphologist judgment. Reasons from coupled form, process, and time and from rates, thresholds, and lag times through field mapping, lidar/SfM DEM morphometry (chi profiles, Ksn in LSDTopoTools/Landlab), cosmogenic nuclide dating (CRONUS-Earth, OSL, U-Th), and landscape-evolution models, while treating equifinality, inheritance, DEM artifacts, and steady-state assumed over transient response as first-class failure modes.

日本語の概要は準備中です。原文の説明を表示しています。

Audit and fix all Lattice documentation, README, docs/, PROJECT.md, GitHub issue templates, and CLAUDE.md to ensure they are fully aligned with the current skill inventory. Documentation drift is the most common source of user confusion in Lattice — a skill exists in the codebase but not in the docs, or a renamed skill leaves a stale reference in the bug report template. If you've made any change to skills/ and haven't run this, run it now. Use when the user says 'align docs', 'audit docs', 'update documentation', 'skill align', 'check docs are in sync', 'audit skill inventory', 'ensure docs are aligned', 'are the docs up to date', or 'what needs updating'. Standalone — does not call other skills.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when planning, capturing, processing, validating, troubleshooting, or exporting markerless human motion capture with Move AI products, including Move One single-camera workflows and Genesis multi-camera studio systems. It covers provider selection, setup, calibration, wardrobe and lighting constraints, documented multi-person operation, processing, cleanup, skeleton and retargeting choices, DCC/game-engine export, data management, consent, and privacy. Do not use it for general keyframe animation, non-Move mocap systems, 3D asset generation, or generic animation cleanup unrelated to Move AI outputs.

日本語の概要は準備中です。原文の説明を表示しています。

Production guidance for assessing, exporting, packaging, integrating, capturing, validating, and handing off Lottie vector animations. Use for Bodymovin/Lottie JSON, dotLottie archives, renderer and player compatibility, fonts and glyphs, image assets, markers and segments, deterministic video capture, responsive sizing, optimization, accessibility, and cross-platform QA; not for general After Effects animation craft or live-action/video delivery.

日本語の概要は準備中です。原文の説明を表示しています。

Calculate TAM/SAM/SOM for market opportunities using top-down, bottom-up, and value theory methodologies. Use this skill when sizing markets, estimating addressable revenue, validating market opportunity for a new venture, or building investor-ready market analysis for a startup pitch or business plan.

日本語の概要は準備中です。原文の説明を表示しています。

Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

日本語の概要は準備中です。原文の説明を表示しています。

Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

日本語の概要は準備中です。原文の説明を表示しています。

Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.

日本語の概要は準備中です。原文の説明を表示しています。

Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

日本語の概要は準備中です。原文の説明を表示しています。

Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end biomarker discovery workflow from expression data to validated biomarker panels. Covers feature selection with Boruta/LASSO, classifier training with nested CV, and SHAP interpretation. Use when building and validating diagnostic or prognostic biomarker signatures from omics data.

日本語の概要は準備中です。原文の説明を表示しています。

Structure prediction using Chai-1, a foundation model for molecular structure. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For ESM-based analysis, use esm.

日本語の概要は準備中です。原文の説明を表示しています。

Chai-1 structure prediction for protein complexes and design validation. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For ESM-based analysis, use esm2-sequence-scoring.

日本語の概要は準備中です。原文の説明を表示しています。

Boltz-1 / Boltz-2 structure prediction for proteins, complexes, and ligand-aware validation. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For Chai prediction, use chai1-structure-prediction.

日本語の概要は準備中です。原文の説明を表示しています。

AlphaFold2 / AlphaFold-Multimer structure prediction for validation and confidence scoring. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm2-sequence-scoring. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For Chai prediction, use chai.

日本語の概要は準備中です。原文の説明を表示しています。

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Use when adding, removing, or updating a local organizer on a devopsdays event team - covers the team_members entry, the photo, and the mandatory email to info@devopsdays.org that gates the merge.

日本語の概要は準備中です。原文の説明を表示しています。

Use when starting, continuing, updating, exporting, or sharing a running transcript of a MATLAB AI tutoring session, especially when the transcript will be shared with an instructor, attached to a learner session report, or passed to an evaluation workflow for quality review.

日本語の概要は準備中です。原文の説明を表示しています。