「eth」の検索結果

Update Java test classes and methods to work with new code versions after refactoring or modifications. Use when code changes break existing tests due to signature changes, refactoring, or behavior modifications. Takes old and new code versions plus old tests as input, and outputs updated tests that compile and pass against the new code. Handles method signature changes, class refactoring, assertion updates, and mock modifications.

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Automatically complete partial code snippets while satisfying semantic constraints including variable types, invariants, pre/post-conditions, interface contracts, and expected input/output behavior. Use when users provide incomplete code with specific requirements like "complete this function that takes a list and returns sorted unique elements" or "fill in this method body that must maintain the invariant that x stays positive" or "implement this interface method with these type constraints." Produces compilable, executable code with tests and a constraint satisfaction report.

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Run a cumulative daily or retrospective sweep of research papers on a chosen topic, audit their claims, methods, integrity signals, and independent support, then identify overlooked but feasible project or business opportunities in a detailed source-grounded report. Use when asked to monitor papers every day, mine buried research, evaluate whether a paper is credible or reproducible, find unimplemented research ideas, or separate promising work from hype, weak evidence, and retracted or contradicted results.

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Map the big picture around a topic or software repository by identifying its boundaries, layers, actors, components, relationships, flows, history, fault lines, and open questions, then explain how the pieces fit together and where to look next. Use when a user asks to understand a whole field, domain, technology, ecosystem, industry, codebase, architecture, unfamiliar repo, or phrases such as "give me the big picture", "map the landscape", "how does this all fit together?", "help me get oriented", or "what am I missing?"

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Standardized trade idea template, multi-method price target derivation PE and sales multiple approaches, GAAP to non-GAAP reconciliation, base bull bear scenario construction, investment thesis structuring, Zendesk-style case methodology

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Valuation methods analysis, DCF inputs, comparable multiples, P/E ratio, EV/EBITDA, price to book, valuation assumptions, relative valuation, intrinsic value, fair value estimate

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Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Li & Hart 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving 2-3x sensitivity over MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).

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End-to-end pooled and single-cell CRISPR screen analysis from FASTQ to hit genes. Orchestrates library design QC, guide counting, six-stage screen QC (plasmid Gini, replicate Pearson, CEGv2 PR-AUC, copy-number artifact), method-appropriate hit calling across MAGeCK RRA/MLE, BAGEL2, drugZ, JACKS, and Chronos, cancer-cell-line copy-number correction (CRISPRcleanR / Chronos), batch correction for multi-batch screens, and the specialized branches for combinatorial paralog screens, single-cell Perturb-seq, base-editor variant-function screens, prime-editor screens, and in vivo bottleneck-aware screens. Use when analyzing any pooled CRISPR screen end-to-end, choosing the correct hit-calling method by experimental design, integrating copy-number correction into the pipeline, or branching the workflow for single-cell, combinatorial, base-editor, prime-editor, or in vivo variants.

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Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Cell Reports 36:109597), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.

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Test whether two or more traits share a causal variant at a locus using Bayesian colocalization (coloc.abf, coloc.susie, HyPrColoc, moloc, eCAVIAR, SMR/HEIDI, PWCoCo, SharePro). Use when integrating GWAS with eQTL/sQTL/pQTL/mQTL, distinguishing shared causal variants from LD-driven coincidence, handling allelic heterogeneity, choosing between single-causal vs multi-causal methods, picking PP.H4 thresholds, running sensitivity over p12, or harmonising summary statistics for colocalization.

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Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information. Use when aligning WGBS, RRBS, or other bisulfite-converted sequencing reads to a reference genome.

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Internal — for Boundless team members only. Audit native ETH, market deposit, prover collateral, and distributor ZKC reserve balances for every operator-managed address (provers, distributor, order generators, signal). Use when the user wants to know which addresses need topping up, asks about the balance of provers/OGs/distributor/signal signers, says something is "running low" or "out of gas", or wants a periodic operational health check on operator wallets. Defaults to prod env (mainnets + prod testnets) — pass `--all` to also include staging.

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Guidance for using Generator.Equals — a C# source generator for auto-generating Equals, GetHashCode, operators, and Diff/Inequalities methods via attributes.

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Verifies whether code follows Spring Modulith code structure or not. Show list of violations along with recommendations on how to fix them. Use this skill: * When reviewing Spring Boot applications which uses Spring Modulith * When verifying whether Spring Boot application code follows Spring Modulith package structure

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Install the PRD-Driven Context Engineering methodology into a fresh OR existing repository — the subscription-native alternative to forking the whole repo. Runs an interactive wizard that seeds the framework (.claude/ hooks, skills, agents, rules, scripts) without clobbering product content. Triggers on "install the methodology", "adopt this into my repo", "self-install", "set up PRD lifecycle here", "onboard existing project". Outputs an installed framework + a verification report.

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Expert in Ethereum L2 solutions - Optimism, Arbitrum, zkSync, Base, and rollup architecture for scalable dApp developmentUse when "layer 2, l2, optimism, arbitrum, zksync, base, rollup, op stack, scaling, layer2, optimism, arbitrum, zksync, base, rollup, scaling, ethereum" mentioned.

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Expertise in F2P economics, virtual currencies, and ethical monetization strategiesUse when "game monetization, F2P economy, in-app purchase, IAP strategy, battle pass design, loot box, gacha system, virtual currency, player LTV, whale monetization, game economy balance, premium currency, season pass, daily rewards, pay to win, ethical monetization, monetization, f2p, free-to-play, iap, in-app-purchase, battle-pass, season-pass, gacha, loot-box, virtual-economy, game-economy, ltv, arpu, retention, whales, pricing, microtransactions" mentioned.

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Expert in Ethereum Virtual Machine internals - gas optimization, assembly/Yul, opcode-level optimization, and low-level EVM patternsUse when "evm, gas optimization, yul, inline assembly, opcodes, solidity optimization, evm bytecode, storage layout, evm, ethereum, solidity, yul, assembly, gas-optimization, opcodes, smart-contracts" mentioned.

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Audit experiment integrity against the evidence ledger. At L2 (repo + result files present) a fresh cross-model reviewer reads the eval code line-by-line for fake/derived ground truth, score self-normalization, phantom results (a paper number with no backing file/key), dead/uncalled metric code, verified-scope inflation, method-described ≠ method-evaluated drift, synthesized-looking results, placeholder/fake data still wired into a released result, code-output ≠ reported-number mismatch, and missing reproducibility artifacts (an empirical/agent/LLM paper shipping neither code nor the prompts/configs its results need) — every finding span-anchored to a ledger claim_id. At L0/L1 (PDF / source only) the same patterns are surfaced as info-level 'could-not-verify' signals where the ledger gives an anchor (observability_level_required:2) — NEVER a fraud verdict from a PDF. The reviewer PROPOSES findings; tools/adjudicate_findings.py computes the verdict. Detect-only. Triggers: "experiment forensics", "audit the results", "check the eval code", "实验诚实度".

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Flagship intra-paper self-consistency forensics: does the paper contradict ITSELF across abstract/intro/tables/body/appendix, and does the method DESCRIBED match the method EVALUATED? Needs no external ground truth — works PDF-only (L0). Runs a deterministic arithmetic pass + a fresh cross-model semantic pass, every finding span-anchored to the evidence ledger (claims.json), reviewer≠adjudicator. Emits consistency-audit.findings.json; NEVER computes the verdict. Triggers: "consistency audit", "check the paper against itself", "self-consistency", "内部自洽".

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Build the deterministic evidence ledger (artifact_manifest.json + claims.json) that every other Anti-Autoresearch auditor reads. One pass inventories artifacts, derives the observability level (L0 PDF-only / L1 +LaTeX / L2 +repo+results) by fixed rule, and extracts span-anchored, hashed, checkable claims (numbers, comparisons, scope, method, baselines, citations, captions, table cells) into claims.json. An OPTIONAL additive cross-model pass ADDS span-anchored semantic claims — method, theorem statements with their assumptions, definitions, proof/derivation steps and equations, scope, baselines, conclusions, the motivation span, and reproducibility-artifact references (the proof, derivation, and structure anchors the family B/D/G auditors need) — it never invents a number, emits a finding, or computes a verdict. Run FIRST, before any audit skill. Triggers: "build the ledger", "extract claims", "prep for integrity audit", "evidence ledger", "建证据账本".

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影视编剧 (Scriptwriting / Screenwriting) — 为电影 / 电视 / 流媒体剧集写戏剧蓝本的从业者认知操作系统: 决定「讲什么故事、人物是谁为何转变、场景如何被戏剧化、主题为何重要」的学科 —— 区别于导演 (调度 / 视觉实现)、制片 (融资 / 排期)、小说 (无格式 / 场景 / 视觉动作约束)。覆盖 (a) 故事与结构理论 (亚里士多德《诗学》情节 / 人物 / 思想 + 突转 peripeteia / 发现 anagnorisis + 净化 catharsis; Syd Field 范式 / 三幕 / 情节点; Freytag 金字塔; Egri 前提; McKee《故事》掌控性理念 / 鸿沟 / 价值正负转变 / 激励事件 / 渐进式复杂化; Truby《故事剖析》22 步 + 道德论证; Vogler/Campbell 英雄之旅; Blake Snyder《救猫咪》15 拍节拍表; Dan Harmon 故事环; John Yorke 五幕《进入森林》; Frank Daniel 八序列法; 起承转合东亚戏剧结构), (b) 人物 (想要 vs 需要 / 外在目标 vs 内在缺失, 人物弧光 正 / 负 / 平, flaw-wound-ghost 创伤背景, 主动 vs 被动主角的能动性, Egri 三维人物 生理 / 社会 / 心理, 反派是主角的镜子, 群像与关系网, 人物在压力下的选择中显形), (c) 对白 (潜台词 subtext, 对白即动作与冲突而非信息, 避免太直白 on the nose, 人物独特声口, 信息植入 exposition, Mamet/Sorkin 意图-阻碍式对白, 展示而非告知, 中文剧台词工艺), (d) 场景与序列工艺 (场景是有目标 / 冲突 / 转折的微型故事, 场景价值充能与转折点, 晚进早出, 八序列法, set piece, 转场, 场景头 / 动作行 / 括号提示 格式工艺), (e) 主题与前提 (掌控性理念 / 前提, 主题是被戏剧化的论证而非说教, 道德论证 Truby, 主题统一性, 这到底在讲什么), (f) 类型 (类型惯例是对观众的承诺, Snyder 10 类故事, 颠覆 vs 尊重套路, 类型片 vs 文艺片, 中国类型 主旋律 / 古装 / 年代 / 悬疑 / 甜宠 / 都市 / 军旅 / 历史正剧), (g) 格式与工业流程 (好莱坞剧本格式与 Final Draft, logline 一句话故事, treatment 故事大纲, 节拍表, 分场 / 分集大纲, spec 原创剧本 vs 委托, pitch, coverage, 美剧编剧室与 showrunner 制; 中国 大纲→人物小传→分集大纲→剧本, 长剧集 40 集结构, 网络电影 / 网大, 分账剧, 平台定制剧, 微短剧竖屏短剧), (h) 改稿与开发 (写作就是改写, 改稿 / 润色 / 推倒重写, 处理意见 / 改稿意见, 片方与平台 notes, 杀死你的宝贝, 围读, 开发地狱), (i) 改编 (IP改编 小说 / 漫画 / 游戏改编, 忠于精神而非字句, 压缩, 中国网文 IP 热), (j) 中国影视编剧产业现实 (审查 / 广电总局约束, 备案 / 立项, 平台定制剧 爱优腾芒, 分账, 编剧维权 署名权 / 欠薪 / 枪手, 注水剧, 流量 + 大IP 资本逻辑 vs 原创工艺, 导演中心制 vs 编剧话语权), (k) 编剧职业与工艺生涯 (spec vs 委托, 编剧 vs 编审 / 策划, 单兵 vs 编剧室, 在开发链条中的位置, WGA 与署名仲裁规范, 入行, 中国编剧地位与权益)。跨 电影 / 美剧流媒体 / 中国电影与长剧集。不含 导演 / 摄影 / 制片 / 融资 / 表演 / 电影理论批评为终点 / 泛小说写作 / 纪录片 / 新闻 —— 本 skill 是「戏剧化编剧」工艺: 故事 / 人物 / 场景 / 对白 / 主题 / 结构 / 格式 与围绕它们的产业流程。 (Scriptwriting / Screenwriting for film & TV (影视编剧) — the cognitive operating system of practitioners who write the dramatic blueprint of films, television, and streaming series: the discipline of deciding WHAT story is told, WHO the characters are and why they change, HOW the scenes are dramatized, and WHY it matters thematically — distinct from directing (staging/visual realization), producing (financing/scheduling), and prose fiction (which has no format/scene/visual-action constraints). Covers (a) story & structure theory (Aristotle's Poetics — plot/character/thought + reversal peripeteia/recognition anagnorisis + catharsis; Syd Field's paradigm/three-act/plot points; Freytag's pyramid; Lajos Egri's premise; Robert McKee's Story — controlling idea/the gap/value charge/inciting incident/progressive complications; John Truby's 22 steps & moral argument; Christopher Vogler/Joseph Campbell hero's journey; Blake Snyder's Save the Cat 15-beat sheet; Dan Harmon's story circle; John Yorke's 5-act Into the Woods; Frank Daniel's 8-sequence method; 起承转合 East-Asian dramatic structure), (b) character (want vs need/external goal vs internal lack, character arc positive/negative/flat, 人物弧光, flaw-wound-ghost backstory, agency active vs passive protagonist, Egri's 3-dimensional character physiology/sociology/psychology, antagonist as the protagonist's mirror, ensemble & relationship webs, character revealed through choice under pressure), (c) dialogue (subtext 潜台词, dialogue as action & conflict not information, 'on the nose' avoidance, distinct character voice, exposition handling, Mamet/Sorkin intention-obstacle dialogue, show-don't-tell, 台词 craft in Chinese drama), (d) scene & sequence craft (scene as a mini-story with goal/conflict/turn, scene value charge & turning point, enter-late-leave-early, the 8-sequence method, set pieces, transitions, slug line/action line/parenthetical format craft), (e) theme & premise (controlling idea/premise/前提, theme as dramatized argument not message, moral argument Truby, thematic unity, 'what is this really about'), (f) genre (genre conventions as audience promise, Snyder's 10 story types, subverting vs honoring tropes, 类型片 vs 文艺片, Chinese genres 主旋律/古装/年代/悬疑/甜宠/都市/军旅/历史正剧), (g) format & industry process (Holly

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Read Bluesky/ATProto without depending on Bluesky's AppView — interactions on a user's posts, thread replies, any repo's records, network-wide backlinks across every lexicon, an account's handle and PDS history, which collections are active network-wide, and layer-by-layer outage diagnosis. Use when bsky.app or the AppView is down or slow, when a Bluesky read returns timeouts or 5xx, when asked who liked/replied/quoted/reposted something, when pulling live Bluesky context cheaply, when reading records straight from a PDS, when asked who references a record or account anywhere on the network, whether an account has changed handle or migrated servers, or which lexicons and non-Bluesky apps are active on atproto. Complements browsing-bluesky, which routes everything through the AppView and fails when it does.

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Mandatory pre-code gate and definition-of-done for ANY Odoo change (add field, override method, inherit view/xpath, OWL/JS patch, wizard, cron, controller, report, security, migration, bug fix, refactor, "optimize", "clean code", "stick to base"), Odoo 16-19. Also when the user pastes an Odoo traceback or install/upgrade error (ParseError "cannot be located in parent view", "Field ... does not exist", missing xmlid) or asks where an Odoo model, field, method, view or xmlid is defined. Run BEFORE brainstorming or planning: Odoo design questions are answered by tracing the real source into a Context Brief (file:line), not by open-ended Q&A or memory. Resolves the Odoo runtime and version, loads the matching odoo-<major> pack, and closes with install, test, upgrade, i18n, security and hygiene checks before commit.

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