「metrics」の検索結果

Quality control for IMC/MIBI data across pixel, channel, image, slide, and batch levels, covering Poisson-count SNR (cell-level Gaussian-mixture and empty-channel comparison), spillover-matrix QC (the three physical sources), drift and the missing EQ-bead analog, acquisition artifacts, and sample-of-origin batch effects. Use when deciding whether to keep or drop a channel, ROI, or slide, distinguishing a dim antibody from a failed one, reading a spillover matrix, or diagnosing batch-driven clustering before analysis.

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Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT for T2T), extracting contigs from GFA and routing phasing QC to k-mer/trio metrics. Covers why a primary assembly is a haplotype mosaic that exists in no cell, partial-vs-full phasing (the .bp. vs .dip. filename convention), the purge-default trap on inbred samples, the --hom-cov coverage-estimate alarm, and verkko-vs-hifiasm for T2T. Use when assembling a diploid eukaryote from HiFi, phasing haplotypes with parents (trio) or Hi-C, deciding whether to chase T2T, or diagnosing switch errors invisible to N50/BUSCO/QV.

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Analyzes species-environment relationships with constrained ordination (CCA, RDA, db-RDA), variance partitioning, indicator species (indicspecies IndVal.g group-equalized), PERMANOVA paired MANDATORILY with PERMDISP (Anderson & Walsh 2013; dispersion confounds centroid tests), Joint Species Distribution Models (HMSC, sjSDM, gjam) with explicit rejection of "residual covariance equals biotic interaction", phylogenetic community ecology (SES_MPD/MNTD), trait-environment via RLQ + fourth-corner with corrected modeltype=6 (Dray 2014), bipartite network metrics (NODF, modularity) with curveball null (Strona 2014), and Mantel-test replacements (dbRDA, GDM) for spatial data. Use when testing how environmental gradients structure communities, identifying habitat indicator taxa, partitioning variance among predictors, deciding whether PERMANOVA significance is location vs dispersion, picking among HMSC/sjSDM/gjam, or replacing Mantel tests for landscape data.

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Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

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Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).

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Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics. Use when verifying alignment data quality before variant calling or quantification.

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Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics. Use when comparing alignment quality, measuring sequence divergence, and analyzing evolutionary patterns.

日本語の概要は準備中です。原文の説明を表示しています。

Access research-grade sensor data using SensorKit for approved studies. Use when an app needs SensorKit entitlement setup, Research Sensor & Usage Data authorization, ambient light, recorded motion, device usage, keyboard metrics, visits, speech, face, wrist temperature, ECG, PPG, acoustic settings, or sleep-session data. Route ordinary motion to CoreMotion and health records/workouts to HealthKit.

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Read, write, and query Apple Health data using HealthKit. Covers HKHealthStore authorization, sample queries, statistics queries, statistics collection queries for charts, saving HKQuantitySample data, background delivery, workout sessions with HKWorkoutSession and HKLiveWorkoutBuilder, HKUnit, and HKQuantityTypeIdentifier values. Use when integrating with Apple Health, displaying health metrics, recording workouts, or enabling background health data delivery.

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Guides Metronome usage-based billing integration decisions — event ingestion (single and batch, idempotency, billable metrics), contract design (rate cards, overrides, dimensional pricing, products), invoicing lifecycle (grace periods, finalization, Stripe sync), credit and commit management (prepaid, postpaid, thresholds, auto-recharge), and Stripe integration (arrears invoicing, tax providers, line item limits). Use when building, modifying, or reviewing any Metronome integration — including ingesting usage events, creating customers, contracts, or rate cards, designing billable metric group keys, managing credits and commits, configuring invoicing, syncing invoices with Stripe Billing, billing AI applications for token usage, setting up self-serve (PLG) pricing, reviewing customer health, commit burn, portfolios, or renewals, or migrating from Stripe Billing Meters to Metronome.

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This skill should be used when user asks about "GCloud logs", "Cloud Logging queries", "Google Cloud metrics", "GCP observability", "trace analysis", or "debugging production issues on GCP".

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Launch and control the MATLAB Radar Designer app programmatically via MCP. Use when designing radar systems, configuring parameters, comparing radar types, analyzing performance metrics, or managing radar design sessions.

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Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA. Use when asked to fit, estimate, calibrate, or compute PK metrics.

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Use when the user wants to train, compare, or export machine learning models using Classification Learner or Regression Learner — including opening the app, loading data, training models, evaluating metrics, comparing results, visualizing plots, testing on held-out data, exploring model interpretability, and exporting trained models. Programmatic access to Classification Learner and Regression Learner apps via AppController.

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AWS CloudWatch monitoring for logs, metrics, alarms, and dashboards. Use when setting up monitoring, creating alarms, querying logs with Insights, configuring metric filters, building dashboards, or troubleshooting application issues.

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AWS EC2 virtual machine management — instances, security groups, key pairs, AMIs, EBS volumes, Auto Scaling Groups, Spot Instances, Session Manager, placement groups, and instance lifecycle automation. Trigger on ANY of these, even when EC2 isn't named explicitly: - Launching or provisioning: "spin up a server", "create a VM", "new instance", "run-instances", mention of instance types (t3, m5, c5, r6, g5, p4d, t4g, c7g, etc.) - SSH / connectivity problems: "connection refused", "connection timed out", "permission denied publickey", "can't connect to my instance", "SSH not working" - Instance management: resize, stop, start, terminate, reboot, change instance type - Cost optimization: stop dev instances overnight, save money on EC2, spot vs on-demand, reserved instances - Auto Scaling: ASG, launch template, mixed instances policy, scale to zero, scheduled scaling - Spot Instances: spot fleet, spot interruption, capacity-optimized, price-capacity-optimized - AMIs and backups: create image, custom AMI, EBS snapshot, DLM lifecycle policy, copy AMI - Monitoring: EC2 CPU utilization, CloudWatch metrics for instance, instance status checks, console output - Access methods: Session Manager, EC2 Instance Connect, bastion host, port forwarding - Security: IMDSv2, instance metadata, IAM role on instance, security group rules - User data and bootstrap scripts, cloud-init

日本語の概要は準備中です。原文の説明を表示しています。

Reduce AWS spend with rightsizing, autoscaling, commitment planning, and storage lifecycle policies. Use when running FinOps reviews, lowering cloud bills, or improving cost-per-request metrics.

日本語の概要は準備中です。原文の説明を表示しています。

Auto-scale LLM inference clusters on Kubernetes using KEDA, custom GPU metrics, and horizontal pod autoscaling. Handle traffic spikes, implement queue-based scaling, and optimize cost with spot instances for AI workloads.

日本語の概要は準備中です。原文の説明を表示しています。

Monitor and evaluate RAG systems with retrieval quality metrics, groundedness checks, hallucination detection, and continuous regression testing.

日本語の概要は準備中です。原文の説明を表示しています。

Instrument AI agents with tracing, token metrics, latency, and cost visibility. Use for reliability and debugging.

日本語の概要は準備中です。原文の説明を表示しています。

Instrument applications and infrastructure with OpenTelemetry for unified traces, metrics, and logs. Use when implementing distributed tracing, service-level troubleshooting, or vendor-neutral observability.

日本語の概要は準備中です。原文の説明を表示しています。

TikTok Shop product differentiation strategy tool. Analyze viral product trends, competitor affiliate strategies, content performance, and identify differentiation opportunities. Includes TikTok-specific metrics like engagement rate, viral potential, and creator collaboration insights. No API key required.

日本語の概要は準備中です。原文の説明を表示しています。

Shopify/DTC product differentiation strategy tool. Analyze competitor stores, extract pain points from reviews, identify brand positioning opportunities, and generate actionable differentiation strategies. Includes DTC-specific metrics like CAC, LTV, and brand story analysis. No API key required.

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Analyze financial data, calculate financial ratios, and generate analysis reports. Use when the user asks about revenue, costs, profits, margins, ROI, financial metrics, or needs financial analysis of a company or project.

日本語の概要は準備中です。原文の説明を表示しています。