「present」の検索結果

Identify tumor neoantigens from somatic variants with pVACtools (pVACseq/pVACfuse/pVACbind/pVACvector/pVACview) for personalized cancer vaccines and checkpoint biomarkers. Encodes the field's hard truth that binding prediction is the easy, near-solved part and single-digit-percent PPV lives downstream — so it centers clonality/CCF, HLA LOH (the silent invalidator), expression, proximal-variant phasing, agretopicity/foreignness quality, and the predicted->presented->immunogenic validation tiers. Use when nominating vaccine targets, ranking neoantigens, or building a tumor-to-candidate pipeline. Binding details in mhc-binding-prediction; ranking in immunogenicity-scoring.

日本語の概要は準備中です。原文の説明を表示しています。

Processes eDNA metabarcoding from raw paired-end reads to species tables, navigating ASV (DADA2, UNOISE3) vs OTU (swarm v2) decision (Callahan 2017 vs Schloss multi-copy-16S critique), marker/primer choice (Leray COI, MiFish 12S, 515F/806R 16S, ITS2) with primer-specific bias, OBITools3 v3 command-name break (obi stats plural; .tar.gz taxonomy), tag-jumping with dual-indexing (Schnell 2015; NovaSeq 10x MiSeq), decontam as screening-not-classifier (Davis 2018), read-counts-not-abundance critique (Lamb 2019), site-occupancy modeling (Ficetola 2015), Naive-Bayes calibration limits (Bokulich 2018), and eDNA decay (Strickler 2015). Use when going from raw eDNA FASTQ to species tables, picking marker + denoising pipeline, deciding whether read counts represent abundance, applying occupancy modeling, configuring OBITools3 v3, or interpreting decontam output. Not for clinical 16S microbiome (see microbiome/amplicon-processing).

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Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf TrueType embedding, programmatic aes via tidy evaluation, and the theme_classic publication baseline. Use when producing static figures in R for papers, presentations, or reports.

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Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.

日本語の概要は準備中です。原文の説明を表示しています。

Install, instrument and verify a web app end to end without pausing for a human. Use in an autonomous or goal-mode agent, in CI, or in any client that asks for approval on every command: it never says "restart your client" or "open a browser", because it takes a route that needs neither. Prefer the normal install-and-verify skill when a human is present and can answer.

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Implement and review Apple TipKit feature-discovery UI for iOS 17+ apps. Use when adding or auditing in-app tips, contextual help, coach marks, Tip, TipView, popoverTip, rules, events, actions, display frequency, testing overrides, reusable tip identifiers, or iOS 18+ TipGroup and CloudKit tip sync; avoid for generic SwiftUI navigation or layout outside tip presentation.

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Implement SwiftUI navigation patterns including NavigationStack, NavigationSplitView, sheet presentation, tab-based navigation, and deep linking. Use when building push navigation, programmatic routing, multi-column layouts, modal sheets, tab bars, universal links, or custom URL scheme handling.

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Implements keyboard, directional, and scene-level focus behavior across SwiftUI and UIKit. Use when managing @FocusState, defaultFocus, focused values, focusable interactions, focus sections, tvOS geometric focus and Siri Remote navigation, watchOS Digital Crown input, visionOS connected-device focus versus gaze hover/input targets, macOS key view loop and Full Keyboard Access, focus restoration after presentation changes, custom focus routing with UIFocusGuide, or debugging focus with UIFocusDebugger.

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Discover and configure Bluetooth and Wi-Fi accessories using AccessorySetupKit. Use when presenting a privacy-preserving accessory picker, defining discovery descriptors for BLE or Wi-Fi devices, handling accessory session events, migrating from CoreBluetooth permission-based scanning, or setting up accessories without requiring broad Bluetooth permissions.

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Implement AlarmKit alarms and countdown timers for iOS and iPadOS with Lock Screen, Dynamic Island, StandBy, and paired Apple Watch system UI. Covers AlarmManager scheduling, AlarmAttributes and AlarmPresentation, system Stop and AlarmButton secondary actions, authorization, state observation, countdown widget-extension handoff, and Live Activity integration. Use when building wake-up alarms, countdown timers, or alarm-style alerts that need Apple's system alarm experience.

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Create, read, and manage calendar events and reminders using EventKit and EventKitUI. Use when adding events to the user's calendar, creating reminders, setting recurrence rules, requesting calendar or reminders access, presenting event editors, choosing calendars, handling alarms, observing calendar changes, or working with EKEventStore, EKEvent, EKReminder, EKCalendar, EKRecurrenceRule, EKEventEditViewController, EKCalendarChooser, or EventKitUI views.

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Build investor-ready pitch scripts in multiple formats (10-min, 5-min, 2-min, 1-min elevator, investor email). Produces pitch narratives, Q&A preparation, pitch scoring rubric, and optional investor roleplay practice. Use when the user wants to create a pitch, prepare for investor meetings, craft a startup pitch, write a fundraising narrative, or practice their pitch. Triggers for "pitch deck", "investor pitch", "pitch my startup", "fundraising deck", "seed deck", "how to pitch", "investor meeting", "demo day", "prepare pitch", "pitch script", "elevator pitch for investors", "pitch practice", "practice my pitch", "investor roleplay", or any request to present a startup to investors, accelerators, or partners. Works standalone — no prior startup-design session needed, but leverages its output if available.

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Create and edit presentation slide decks (`.pptx`) with PptxGenJS, bundled layout helpers, and render/validation utilities. Use when tasks involve building a new PowerPoint deck, recreating slides from screenshots/PDFs/reference decks, modifying slide content while preserving editable output, adding charts/diagrams/visuals, or diagnosing layout issues such as overflow, overlaps, and font substitution.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when creating Ultralytics-branded content of any kind, including PDF, PPTX, Canva, or Google Slides presentations, DOCX documents, marketing or newsletter HTML emails, social media post copy or visuals, website or landing page designs, and dataset or model result visuals. Provides official colors, typography, logo rules, naming rules, and tone of voice from ultralytics.com/brand.

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Optional design-improvement pass for when you have spare usage to drain. Finds the shallowest modules in the code the spec touches, researches a deeper design, and proposes refactors that shrink interfaces and hide decisions — behavior held constant, tests green before and after. Proposes §I/§V/§T edits, never silent rewrites. Triggers when the user says "deepen this", "improve the design", "this module feels shallow", "pull complexity down", "use spare budget on the codebase", or invokes /ck:deepen. Leans on the codebase-design skill's deep-module vocabulary when present.

日本語の概要は準備中です。原文の説明を表示しています。

Write a client proposal, quote, scope of work, or engagement letter for a service business. Covers project understanding, scope, timeline, pricing presentation, and terms. Use whenever the user asks for a proposal, quote, project proposal, client proposal, SOW, statement of work, engagement letter, or B2B service engagement document — for web dev, consulting, trades, or any service business.

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Use when user requests diagrams, flowcharts, architecture charts, or visualizations. Also use proactively when explaining systems with 3+ components, complex data flows, or relationships that benefit from visual representation. Generates .excalidraw files and exports to PNG/SVG via Kroki API or locally using excalidraw-brute-export-cli.

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When the user wants to submit a product or app to directories, curated lists, launch platforms, or app stores—and needs ready-to-paste copy per platform. Reads root contextus.md when present. Also use when the user mentions "directory submission," "get listed," "app store listing," "submit to directories," "curated list," "best tools list," "Taaft," "Product Hunt," "directory ads," "newsletter feature," "directory campaign," "tailor description per platform," "Shopify App Store," "Chrome Web Store," "navigation site," or "product directory." For Product Hunt launch day tactics (hunter, first comment, timing), use product-hunt-launch. For full 0→1 channel planning, use cold-start-strategy.

日本語の概要は準備中です。原文の説明を表示しています。

Rebuild or restyle editable Microsoft Visio diagrams from reference images and existing .vsdx files, then export deliverables as .vsdx, PNG, SVG, PDF, or PPTX. Use when the user asks Codex to open Visio, recreate a diagram from a PNG/JPG/screenshot/reference image, match a scientific model figure, update colors/typography/layout in a .vsdx, calibrate panel coordinates to avoid shifted or overlapping submodules, or make publication/presentation outputs while preserving Visio native editable shapes rather than embedding the reference image as a flat picture.

日本語の概要は準備中です。原文の説明を表示しています。

Internal implementation skill invoked by /add-native for app-generated PDF report workflows using expo-print and, when present, expo-sharing.

日本語の概要は準備中です。原文の説明を表示しています。

Assemble the final `.ppmplugin` binary bundle for a PAM native extension and verify its contents. First **reconciles** the manifest's declared `entrypoints` against the binaries actually staged — if the manifest declares a platform with no built binary it gates (build it / ship without it / stop) rather than shipping a broken bundle. Then re-runs the plugin's upload-compatibility checks on the reconciled manifest, zips the manifest plus whichever of `android/<PascalName>Plugin.dex` and `ios/<PascalName>Plugin.framework/` are present into `ppmplugin/<name>.ppmplugin`, and verifies the archive layout with `jar tf` (exactly the manifest + the shipped binaries — nothing missing, nothing extra). Output: a statically verified `.ppmplugin` file on disk. Prereqs: `jar` (JDK). Run after /generate-ppmplugin-manifest and the build skill(s).

日本語の概要は準備中です。原文の説明を表示しています。

Evaluate an AI workflow against representative cases and its permitted actions. Use for model, retrieval or agent evaluation; tests do not grant release authority.

日本語の概要は準備中です。原文の説明を表示しています。

Generate logo variants for a brand, producing multiple production-grade marks across different architectures (wordmark, lockup, symbol-only, letterform-as-symbol, monogram) with rationale, application specs, and decision-ready presentation. Distinct from `brand-identity`, which produces the complete system (logo plus color, type, voice, applications). Goes deep on the logo specifically: typographic register, symbol approach, application-context discipline (16px favicon, embroidery, signage, motion), and production specs (SVG-ready, single-color, reverse). Triggers on logo design, design a logo, wordmark, monogram, lockup, mark variants, logo iterations, redesign or refine the logo, logo refresh, letterform-as-symbol, and exploring mark variants for an established brand. Does NOT fire for full brand identity (use `brand-identity`), positioning or strategy (use `brand-discovery`), project-wide creative direction (use `creative-direction`), or one-off illustration.

日本語の概要は準備中です。原文の説明を表示しています。