「choice」の検索結果

Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA, Crippen LogP, 3D shape) with explicit choice tables, bit vs count semantics, and partial-charge model selection. Use when featurizing molecules for similarity, QSAR, virtual screening, or ML, or selecting the correct fingerprint for a chemotype-aware task.

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Performs molecular similarity searching using Tanimoto, Tversky, Dice, and cosine coefficients on bit/count fingerprints with explicit choice rules for symmetric vs asymmetric measures, scaffold-hopping vs lead-optimization regimes, activity-cliff diagnosis, and large-library nearest-neighbor methods (BulkTanimoto, Annoy MHFP6, USRCAT). Use when ranking compounds by structural resemblance to a query, clustering libraries, finding analogs, or diagnosing activity cliffs.

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Creates sashimi-style plots showing RNA-seq read coverage and splice junction counts using ggsashimi (general-purpose, condition-grouped overlays), rmats2sashimiplot (rMATS-output-aware), MAJIQ-VOILA (LSV posteriors interactive HTML), leafviz (leafcutter clusters Shiny), Jutils (tool-agnostic heatmaps and sashimi for rMATS/leafcutter/SUPPA2/MAJIQ output), or pyGenomeTracks (multi-track publication figures). Tool choice depends on the upstream differential-splicing tool's output format and the publication vs interactive use case. Use when visualizing specific splicing events, validating differential splicing calls, or producing publication-quality figures.

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Use when users need bioinformatics analysis on the NCPGR cluster, especially when converting analysis requests into local software choices, resource plans, and LSF job scripts.

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Use when an owner-operator (1099 or LLC/S-corp) asks how to lower their tax bill, what they can deduct, per diem treatment, depreciation choices (Section 179, bonus, MACRS), quarterly estimated payments, S-corp salary vs distributions, retirement plan options (SEP-IRA, Solo 401(k)), or recordkeeping requirements. Covers federal income tax + self-employment tax basics; not state-specific.

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Improves typography by fixing font choices, hierarchy, sizing, weight, and readability so text feels intentional. Use when the user mentions fonts, type, readability, text hierarchy, sizing looks off, or wants more polished, intentional typography.

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Create stunning, animation-rich HTML presentations from scratch or by converting PowerPoint files. Use when the user wants to build a presentation, convert a PPT/PPTX to web, or create slides for a talk/pitch. Helps non-designers discover their aesthetic through visual exploration rather than abstract choices.

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Use this skill when working with the nuxt-ui-tools form runtime as a package consumer. It covers schema-driven forms, the provider-backed form API, inline rendering, overlay rendering, form pages with a section navigation, choice cards, and typed submit results.

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Structured decision-making framework for technical proposals and trade-off analysis. When the user faces a choice between multiple approaches (architecture decisions, tool selection, refactoring strategies, migration paths), this skill produces a 1-3-1 format: one clear problem statement, three distinct options with pros/cons, and one concrete recommendation with definition of done and implementation plan. Use when the user asks for a "1-3-1", says "give me options", or needs help choosing between competing approaches.

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Drafts formal explanation letters for Canadian Study Permit applications by structuring the argument around program attractiveness, background relevance, choice rationale, and family benefits.

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Systematically evaluate architecture decisions, document trade-offs, and select appropriate patterns. This skill should be used when the user asks about 'architecture decision', 'ADR', 'design pattern selection', 'technology choice', or needs to evaluate architectural trade-offs. Keywords: architecture, ADR, patterns, trade-offs, technical debt, quality attributes, decision record.

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Apply a named behavioral science framework to any task — persuasion, nudge design, habit formation, conversion, influence, negotiation, cognitive bias, choice architecture, decision framing. The framework backbone every other Maxim skill loops into for psychological validation.

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Simplify cluttered UI by removing unnecessary elements, choices, features, and structural complexity. Use when the problem is too many controls, options, features, or competing elements—not when the structure is sound and the real issue is only visual intensity or lack of personality.

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Improve UI typography by fixing font choices, type scale, hierarchy, weight, and readability so text feels intentional. Use when the user mentions fonts, typography, type scale, readability, text hierarchy, or sizing that feels off.

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Research one bounded mature-project/prior-art question when the user explicitly asks how established projects handle it or ROSE names a decision-shaping prior-art gap; do not trigger automatically for IDEATE, DEFINE, BUILD, implementation, local review, or every design choice.

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Creates Architecture Decision Records documenting key technical decisions with context, alternatives considered, tradeoffs, consequences, and decision owners. Use when documenting "architecture decisions", "technical choices", "design decisions", or "ADRs".

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Use when designing a Spark feature or writing or materially revising a design proposal that needs repository-first research, user input on unresolved key choices, and an owner-aligned implementation plan before code changes.

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Use when a study's materials, data, code, or preprint need an open-science release: license choice, a persistent DOI (Zenodo/OSF), README and metadata, and an access-and-embargo decision that respects ethics constraints.

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Browser automation powers web testing, scraping, and AI agent interactions. The difference between a flaky script and a reliable system comes down to understanding selectors, waiting strategies, and anti-detection patterns. This skill covers Playwright (recommended) and Puppeteer, with patterns for testing, scraping, and agentic browser control. Key insight: Playwright won the framework war. Unless you need Puppeteer's stealth ecosystem or are Chrome-only, Playwright is the better choice in 202

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Guides collaborative requirements discovery before implementation. Creates task directory, seeds PRD, asks high-value questions one at a time, researches technical choices, and converges on MVP scope. Use when requirements are unclear, there are multiple valid approaches, or the user describes a new feature or complex task.

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Requires OFOX_API_KEY — create one at https://app.ofox.ai. Shared execution layer for the Ofox video generation API (api.ofox.ai) — creates a video job, polls it to completion, downloads the finished mp4 from a persistent CDN URL, and reports the real cost. This is a library skill, not a standalone user-facing one — it is invoked by scenario skills such as seedance-short-drama, seedance-ad-creative, and seedance-product-video, which build model/prompt/resolution choices for a specific use case and then call into this skill's script rather than re-implementing the API calls. Load this skill directly only when a user explicitly names the Ofox video API, asks to call it with specific low-level parameters, or asks to debug/resume a stuck or failed Ofox video job by job id — for a plain scenario request ("make me a short drama scene", "generate a cinematic ad clip"), use the relevant scenario skill instead, which itself depends on this one.

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Requires OFOX_API_KEY — create one at https://app.ofox.ai. Shared execution layer for the Ofox image API (api.ofox.ai) — validates parameters client-side, sends one synchronous request, base64-decodes the result, saves it to a file, and reports the real usage token counts and the computed dollar cost. Does both text-to-image (generate) and editing an existing image you supply as a local file (edit — change the background, recolour an element, alter a product photo, while leaving the rest of the picture intact). This is a library skill, not a standalone user-facing one — it is meant to be invoked by scenario skills that build model/prompt/size choices for a specific use case and then call into this skill's script rather than re-implementing the API calls — image-edit owns "change this image so that...", product-image owns a set of product images to choose between, and seedance-anime-drama owns character images for a video pipeline. Load this skill directly only when a user explicitly names the Ofox image API, asks to call it with specific low-level parameters, asks to debug a failed Ofox image request, or wants a plain "generate an image of..." from text — which is the one common case no scenario skill covers.

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Analyze undirected cycle structure within a valid DAG using the source paper's orientation and contraction method. Use for cycle-basis analysis with explicit graph and reduction choices. NOT for directed feedback loops, workflow deadlocks, or runtime resilience claims.

日本語の概要は準備中です。原文の説明を表示しています。