1.3万 件 ・ 関連度順
概要と使いどころ
Generate personalized cold email sequences (7-14 emails) with A/B test subject lines, follow-up timing recommendations, and integrated social proof. Creates multi-touch campaigns optimized for response rates. Use when users need outbound email campaigns, sales sequences, or lead generation emails.
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Fix "Failed to load video" errors when network requests succeed (200/206 status). Use when: (1) Video element shows error but DevTools shows successful requests, (2) Videos download correctly via curl but fail in browser, (3) Range requests work but video won't play, (4) Building CDN/media server for video streaming. The root cause is often missing Accept-Ranges header which browsers need for video seeking and streaming.
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Generates comprehensive test scenarios from requirements including BDD/Gherkin scenarios, unit tests, integration tests, and end-to-end test cases. Use when converting requirements, user stories, or specifications into testable scenarios with full coverage including happy paths, error cases, edge cases, and boundary conditions. Outputs structured test suites ready for implementation.
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Transforms natural language requirements (user stories, verbal descriptions, business rules) into formal specifications and constraints. Use when converting informal requirements into structured, testable specifications with explicit constraints. Outputs in multiple formats including BDD-style Given-When-Then, JSON Schema, and structured plain text requirements documents.
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Generate formal specifications (definitions, predicates, invariants, pre/post-conditions) in Isabelle/HOL or Coq from informal requirements, source code, pseudocode, or mathematical descriptions. Use when users need to: (1) Formalize algorithms or data structures, (2) Create function specifications with contracts, (3) Generate predicates and properties for verification, (4) Translate informal requirements into formal logic, (5) Specify invariants for loops or data structures, or (6) Create formal definitions for mathematical concepts. Supports both Isabelle/HOL and Coq equally.
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Detects and analyzes ambiguous language in software requirements and user stories. Use when reviewing requirements documents, user stories, specifications, or any software requirement text to identify vague quantifiers, unclear scope, undefined terms, missing edge cases, subjective language, and incomplete specifications. Provides detailed analysis with clarifying questions and suggested improvements.
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Create Request for Proposals with requirements specifications, evaluation criteria, scoring rubrics, timelines, and compliance requirements
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Navigate privacy regulations (GDPR, CCPA), review DPAs, and handle data subject requests. Use when reviewing data processing agreements, responding to data subject access or deletion requests, assessing cross-border data transfer requirements, or evaluating privacy compliance.
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Generate templated responses for common legal inquiries and identify when situations require individualized attention. Use when responding to routine legal questions — data subject requests, vendor inquiries, NDA requests, discovery holds — or when managing response templates.
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Think and work like an expert Molecular Geneticist. Use when a task calls for Molecular Geneticist judgment. Reasons from sequence-as-hypothesis, reference context (genome build, MANE/RefSeq transcript, HGVS), and allele-level molecular consequence through ACMG/AMP-ClinGen criteria, IGV/VEP/SpliceAI/gnomAD/ClinVar review, MIQE-compliant qPCR/ddPCR, and Sanger/NGS validation while treating allele dropout, pseudogene/paralog misalignment, FFPE deamination, contamination and barcode bleed, and transcript/build mismatch as first-class failure modes.
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long short equity strategy, pair trade construction, market neutral portfolio, net exposure management, factor neutrality, equity long short, hedge fund strategy, alpha generation, stock picking portfolio construction, long short position management
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The Auto 档 scenario — a soft-plan orchestrator for a complete fundamental equity research thesis: understand → financials → valuation → synthesize. The body is a soft plan (stages), not a rigid DAG; correctness is enforced by each referenced skill's own requires: preconditions, never by this plan's rigidity (Q2).
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Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.
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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.
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Generate consensus FASTA sequences by applying VCF variants to a reference using bcftools consensus. Use when creating sample-specific reference sequences or reconstructing haplotypes.
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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.
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Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
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Run remote BLAST searches against NCBI servers using Biopython Bio.Blast.NCBIWWW. Use when identifying unknown sequences, finding homologs, picking the correct BLAST program (blastn/blastp/blastx/tblastn/tblastx/psiblast/megablast/dc-megablast), interpreting Karlin-Altschul E-values, avoiding the max_target_seqs trap (Shah 2019), choosing composition-based statistics, or limiting searches by organism. Covers RID lifecycle, database choice (nt/nr/refseq_select/swissprot), word-size and CBS taxonomy.
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Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.
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End-to-end ChIP-seq workflow from FASTQ files to annotated peaks. Covers QC, alignment, peak calling with MACS3 (or HOMER), and peak annotation with ChIPseeker. Use when processing ChIP-seq data from alignment through peak annotation.
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Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.
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ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard prep quality, or selecting which replicates to drop before peak calling.
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Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for downstream differential analysis.
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Create, manipulate, and convert bedGraph files for genome browser visualization. Covers bedGraph format, conversion to/from bigWig, normalization, and signal processing. Use when handling coverage and signal tracks from ChIP-seq, ATAC-seq, or RNA-seq.
日本語の概要は準備中です。原文の説明を表示しています。