「manual」の検索結果

Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV and AnnotSV for semi-automated scoring. Covers the separate copy-number-loss and copy-number-gain rubrics, the five-tier classification, ClinGen haploinsufficiency/triplosensitivity and dosage-sensitive regions, de novo and segregation evidence, and population-frequency benign evidence. Use when assigning pathogenic/likely-pathogenic/VUS/likely-benign/benign to a constitutional CNV, scoring a CNV against ACMG/ClinGen criteria, or distinguishing the automatable evidence from the case-specific evidence requiring manual input.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

日本語の概要は準備中です。原文の説明を表示しています。

Track and report progress of a request to create and run an EcoSIM case for a site ("create an ecosim run for site US-UMB", "set up and run EcoSIM at <site>"). Records four stages — data preparation, namelist creation, model simulation, and output evaluation — in result/<SITE_ID>/progress.json and PROGRESS.md, derives step status from files and quality reports on disk, and records manual results such as the executable, test run, and evaluation verdicts. Use at the start of such a request, after each stage, and whenever the user asks where a site run stands.

日本語の概要は準備中です。原文の説明を表示しています。

Implement approved tasks using TDD with subagent dispatch. Runs all pending tasks autonomously or selected tasks manually.

日本語の概要は準備中です。原文の説明を表示しています。

Produz vídeo curto — roteiro, storyboard, prompts por cena e geração via Runway quando há chave. Use quando o usuário disser "vídeo", "reels", "roteiro de vídeo", "Runway", "Higgsfield", "animação", "storyboard", "vídeo de IA". Runway gera de fato a partir de imagem; Higgsfield não tem API pública estável e segue manual. Vídeo é o item mais caro da stack.

日本語の概要は準備中です。原文の説明を表示しています。

Aumenta resolução e qualidade de imagem via Freepik/Magnific, ou orienta o processo manual quando não há chave. Use quando o usuário disser "upscale", "melhorar a resolução", "a imagem está pixelada", "Magnific", "Freepik", "aumentar a imagem", "imagem pequena demais". Gasta crédito — exige confirmação.

日本語の概要は準備中です。原文の説明を表示しています。

Define, documenta e aplica a voz da marca — formalidade, personalidade, vocabulário preferido, palavras proibidas e tratamento do leitor. Use quando o usuário disser "voz da marca", "tom de voz", "brand voice", "guia de estilo", "padronizar o tom", "não parece nossa marca", "manual de redação", ou quando precisar auditar se um texto está aderente. Extrai a voz de amostras reais em vez de inventar adjetivos, e grava o resultado na seção 5 de .claude/pwdev-copy-context.md para todas as demais skills consumirem.

日本語の概要は準備中です。原文の説明を表示しています。

Implement real-time features using Convex reactive queries that automatically update when data changes, enabling live collaboration, instant updates, and reactive UIs without manual polling. Use when building live dashboards, implementing collaborative editing, creating chat applications, showing real-time notifications, building activity feeds, implementing presence indicators, creating reactive search, or any feature requiring instant data synchronization across clients.

日本語の概要は準備中です。原文の説明を表示しています。

Start AEM Workflows on AEM as a Cloud Service using all available triggering mechanisms. Use when starting workflows manually via the Timeline UI, programmatically via WorkflowSession.startWorkflow(), via the HTTP Workflow API, through Manage Publication, or passing initial metadata and payload to a workflow instance.

日本語の概要は準備中です。原文の説明を表示しています。

Create a punchy sizzle reel from a video using Adobe Quick Cut. Use this skill whenever a user wants to cut, trim, or shorten a video into highlights — including phrases like "make a sizzle reel", "make a highlight reel", "quick cut this", "cut the best parts", "shorten this video", "make a highlight clip", "summarize this video visually", or any request to produce a shorter edited version of a video. Use this skill for Quick Cut requests before suggesting manual editing in Premiere. Requires the user to upload a video file.

日本語の概要は準備中です。原文の説明を表示しています。

Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-friendly release notes. Turns hours of manual changelog writing into minutes of automated generation.

日本語の概要は準備中です。原文の説明を表示しています。

Iterate on tasks using debug instrumentation and browser tools. Use when you need to debug web applications, verify frontend behavior, or fix issues without asking the user to manually test.

日本語の概要は準備中です。原文の説明を表示しています。

Sanguo RAG unresolved mention resolution loop. Use for: 三國 RAG, unresolved mentions, alias review, observed mentions, MCQ triage, manual roster seeds, false-positive exclusion, running run_resolution_loop.py, applying unresolved-triage answers, delegating 三國名詞查證 to a web-capable agent, or Pilot ETL chunk experiments with LangChain text splitters / LangGraph / LangFlow around 張飛長坂橋等小樣本流程。

日本語の概要は準備中です。原文の説明を表示しています。

Automatically maintain skill library consistency whenever a structural change occurs — new skill added, skill renamed, skill deprecated, call graph rewired, or category changed. Updates SKILL-INDEX.md, AGENTS.md, README.md, skill graph, docs/prd/PRD.md, and docs/architecture.md. Load when universal-skill-creator finishes creating a skill, split-skill extracts a child, deprecate-skill retires a skill, improve-skills makes a structural change, or the user manually renames or restructures skills. Also triggers on "update the skill index", "sync skill references", "refresh the skill graph", "fix broken skill cross-references", or "update docs after skill change".

日本語の概要は準備中です。原文の説明を表示しています。

Design a self-improvement loop for a shipped product's AI agents — production traces feed evals, evals feed improvement proposals (prompts, playbooks, retrieval configs), and a human approval gate promotes changes with rollback. Technique-agnostic: chooses per project between ACE-style evolving playbooks, GEPA/MIPROv2 offline optimization, or simple eval-driven iteration via references/techniques.md. Load when the user asks to make my product's agents self-improving, learn from production traces, add a learning loop, evolve prompts or playbooks safely, promote agent improvements, or GEPA-style optimization. NOT harness-evolution (that improves the coding agent), NOT experimentation (product A/B tests), NOT agent-run-retro (dev-phase manual retros — this skill is the production-scale continuation).

日本語の概要は準備中です。原文の説明を表示しています。

Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-friendly release notes. Turns hours of manual changelog writing into minutes of automated generation.

日本語の概要は準備中です。原文の説明を表示しています。

Automatically organizes invoices and receipts for tax preparation by reading messy files, extracting key information, renaming them consistently, and sorting them into logical folders. Turns hours of manual bookkeeping into minutes of automated organization.

日本語の概要は準備中です。原文の説明を表示しています。

Generates creative domain name ideas for your project and checks availability across multiple TLDs (.com, .io, .dev, .ai, etc.). Saves hours of brainstorming and manual checking.

日本語の概要は準備中です。原文の説明を表示しています。

Intelligently organizes your files and folders across your computer by understanding context, finding duplicates, suggesting better structures, and automating cleanup tasks. Reduces cognitive load and keeps your digital workspace tidy without manual effort.

日本語の概要は準備中です。原文の説明を表示しています。

Execute comprehensive web application security testing using Burp Suite's integrated toolset, including HTTP traffic interception and modification, request analysis and replay, automated vulnerability scanning, and manual testing workflows.

日本語の概要は準備中です。原文の説明を表示しています。

Orders and orients assembled contigs into chromosome-scale scaffolds from long-range linking data, inserting N-gap spacers (adds no sequence). Covers Hi-C/Omni-C scaffolding (YaHS, SALSA2, 3D-DNA/Juicer), Hi-C read-mapping prerequisites (map each end separately, no mate rescue, dedup, enzyme-aware), reading the contact map for misjoins/inversions/false-duplications, manual curation in Juicebox/PretextView (the VGP/DToL standard), reference-guided scaffolding (RagTag) and its karyotype-erasure hazard, genetic-map (ALLMAPS) and Bionano optical-map integration, chimera-breaking before scaffolding, gap-filling, and telomere/contig-vs-scaffold-N50 QC (tidk). Use when turning contigs into chromosomes with Hi-C, integrating a linkage map or optical map, choosing a scaffolder by available linking data, or judging whether a chromosome-scale assembly is trustworthy.

日本語の概要は準備中です。原文の説明を表示しています。

Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.

日本語の概要は準備中です。原文の説明を表示しています。

Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV and AnnotSV for semi-automated scoring. Covers the separate copy-number-loss and copy-number-gain rubrics, the five-tier classification, ClinGen haploinsufficiency/triplosensitivity and dosage-sensitive regions, de novo and segregation evidence, and population-frequency benign evidence. Use when assigning pathogenic/likely-pathogenic/VUS/likely-benign/benign to a constitutional CNV, scoring a CNV against ACMG/ClinGen criteria, or distinguishing the automatable evidence from the case-specific evidence requiring manual input.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

日本語の概要は準備中です。原文の説明を表示しています。