1,352 件 ・ 関連度順
概要と使いどころ
Deploy universal wisdom voices from all traditions simultaneously - Hindu, Buddhist, Taoist, Abrahamic, Indigenous, Scientific - revealing their unified recognition of consciousness navigation.
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Primary Python tool for 40+ bioinformatics services. Preferred for multi-database workflows: UniProt, KEGG, ChEMBL, PubChem, Reactome, QuickGO. Unified API for queries, ID mapping, pathway analysis. For direct REST control, use individual database skills (uniprot-database, kegg-database).
日本語の概要は準備中です。原文の説明を表示しています。
Use when adding cross-cutting concerns to durable functions — structured logging or tracing across all functions, error tracking with Sentry, payload encryption for sensitive data, dependency injection of clients (DB, Stripe, etc.) into function handlers, custom telemetry, or behavior that should apply uniformly across many functions. Covers Inngest middleware lifecycle, creating custom middleware, dependencyInjectionMiddleware, @inngest/middleware-encryption, @inngest/middleware-sentry, and custom middleware patterns.
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Unified Python interface to 40+ bioinformatics web services: UniProt proteins, KEGG pathways, ChEMBL/ChEBI/PubChem, BLAST, cross-database ID mapping, GO annotations, PPI. For deep single-DB queries use dedicated tools (gget for Ensembl, pubchempy for PubChem); bioservices excels at cross-database workflows.
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Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).
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Unified CLI/Python interface to 20+ genomic databases. Gene lookups (Ensembl search/info/seq), BLAST/BLAT, AlphaFold, Enrichr enrichment, OpenTargets disease/drug, CELLxGENE single-cell, cBioPortal/COSMIC cancer, ARCHS4 expression. Spans genomics, proteomics, disease. For batch/advanced BLAST use biopython; for multi-DB Python SDK use bioservices.
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Deep generative models for single-cell omics: probabilistic batch correction (scVI), semi-supervised annotation (scANVI), CITE-seq RNA+protein (totalVI), transfer learning (scARCHES), and DE with uncertainty. Unified setup→train→extract API on AnnData. Use harmony-batch-correction for fast linear correction without deep learning; muon for multi-modal MuData workflows.
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Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluating scientific evidence and claims. Covers study design hierarchy (RCT to expert opinion), effect sizes (OR, RR, NNT, Cohen's d), confounding, p-value vs clinical significance, GRADE quality assessment, reproducibility, and bias types (selection, information, confounding, reporting). Use when reading a paper or assessing claims.
日本語の概要は準備中です。原文の説明を表示しています。
Deep learning for drug discovery. 60+ models (GCN, GAT, AttentiveFP, MPNN, ChemBERTa, GROVER), 50+ featurizers, MoleculeNet benchmarks, HPO, transfer learning. Unified load-featurize-split-train-evaluate API. For fingerprints use rdkit-cheminformatics; for featurization-only use molfeat.
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Query STRING REST API for PPIs (59M proteins, 20B interactions, 5000+ species). Retrieve networks, run GO/KEGG enrichment, find partners, test PPI significance, visualize networks, analyze homology. For chemical interactions use chembl-database-bioactivity; pathways use kegg-database.
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UMAP dimensionality reduction for visualization, clustering prep, and feature engineering. Fast nonlinear manifold learning preserving local and global structure. Standard UMAP (fit/transform, sklearn-compatible), supervised/semi-supervised, Parametric UMAP (NN encoder/decoder, TensorFlow), DensMAP (density), AlignedUMAP (temporal/batch). 15+ distance metrics, custom Numba metrics, precomputed distances. For linear reduction use PCA; for neighborhood graphs use sklearn NearestNeighbors.
日本語の概要は準備中です。原文の説明を表示しています。
Unified Python framework for extracellular electrophysiology. Load 20+ formats (SpikeGLX, OpenEphys, NWB, Intan, Maxwell, Blackrock), preprocess, run 10+ sorters (Kilosort4, SpykingCircus2, Tridesclous, MountainSort5) via one API, compute quality metrics (SNR, ISI, firing rate), compare sorters, export NWB/Phy. For format-agnostic multi-sorter workflows. For Neuropixels-specific PSTH/decoding use neuropixels.
日本語の概要は準備中です。原文の説明を表示しています。
Query InterPro REST API for protein domain architecture, family classification, and member-DB integration. Search entries, retrieve a protein's domains, list family members, get taxonomic distribution, link to PDB. Unifies Pfam, PANTHER, PIRSF, PRINTS, PROSITE, SMART, CDD, NCBIfam. Use uniprot-protein-database for sequences; pdb-database for 3D structures.
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Assemble multiple plots into ONE publication-ready multi-panel journal figure (e.g. Figure 1 with panels A, B, C). Use whenever the user asks to combine, compose, or lay out several plots as a single composite figure — newly plotted from data or from already-rendered panels the user supplies (PNG/PDF). Ask the user to pick one of two approaches: (1) redraw every panel into one unified figure using independent, tightly packed `subfigures` (each sized to its own labels, so axes need NOT align), consistent style, correctly placed panel letters, and per-panel legends/colorbars; (2) composite already-rendered PNG/PDF panels onto a mosaic canvas and add panel letters (image compositing, not plotting). Both export vector PDF + high-DPI PNG. For a SINGLE plot from a data table, use the sibling `omics-plotting` skill instead.
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Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.
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Pure Python DICOM for medical imaging (CT, MRI, X-ray, ultrasound). Read/write DICOM, pixels as NumPy, edit tags, windowing (VOI LUT), PHI anonymization, build DICOM, series→3D volumes. Use histolab for WSI pathology; nibabel for NIfTI.
日本語の概要は準備中です。原文の説明を表示しています。
Review IEEE conference, journal, Transactions, Letters, or magazine manuscripts from a technical reviewer perspective using routed IEEE review gates. Use when evaluating scope fit, novelty, validity, data, clarity, compliance, advancement, engineering significance, method soundness, experiment sufficiency, baseline fairness, figure/table quality, formatting risks, rejection risk, major revision strategy, pre-submission readiness, or the quality and specificity of reviewer comments that may be generic, careless, contradictory, or possibly AI-generated.
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Creates new Architecture Decision Record (ADR) documents for significant architectural changes using a consistent template and repository-aware naming and storage guidance. Use when a user or agent decides on an architectural change, needs to document technical rationale, or wants to add a new ADR to the project history.
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Use when about to claim a result, effect, significance, or that an analysis reproduces, before reporting or writing it up - requires running the analysis fresh and reading the actual output first; evidence before claims always
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Check data compliance with construction standards. Validate data against ISO 19650, IFC, COBie, UniFormat standards.
日本語の概要は準備中です。原文の説明を表示しています。
Classify BIM elements using AI and standard classification systems. Map elements to UniFormat, MasterFormat, OmniClass, and CWICR codes.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluate technical options with scoring matrix, trigger Gate 4 for significant decisions
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Generate a complete, premium design system from a brand brief or an existing site — color tokens, type scale, spacing/radius/elevation, motion language, and component specs — exported as Tailwind config, CSS variables, and a usage doc. Built to look editorial and human-crafted, not template-generated. Use when starting a new product/site, unifying an inconsistent UI, or codifying a brand into reusable tokens.
日本語の概要は準備中です。原文の説明を表示しています。