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Hybrid ML + physics binding affinity prediction. Empirical scoring, MM/GBSA rescoring, multi-method consensus, and batch virtual screening for protein-ligand complexes.

日本語の概要は準備中です。原文の説明を表示しています。

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

日本語の概要は準備中です。原文の説明を表示しています。

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

日本語の概要は準備中です。原文の説明を表示しています。

Use when implementing a medium or large coding project from a written spec, plan, or product goal where drift, skipped validation, PR correctness, or multi-block delivery risk matter.

日本語の概要は準備中です。原文の説明を表示しています。

Query aggregate Langfuse cost, volume, latency, and model telemetry efficiently with Metrics API v2. Use for dashboards, rollout checks, usage summaries, and cost or latency comparisons; use Observations API v2 instead when individual rows are actually required.

日本語の概要は準備中です。原文の説明を表示しています。

Configure and debug MCP servers for OpenCode, Codex CLI, and Claude Code, including auth headers, scope, and validation checks. Use when MCP tools fail to connect or when adding a new MCP server.

日本語の概要は準備中です。原文の説明を表示しています。

Configure and debug MCP servers for Claude Code, OpenCode, and Codex CLI, including auth headers, scope, and validation checks. Use when MCP tools fail to connect, when an MCP server returns 401/404/HTML, or when adding a new MCP server to this repo.

日本語の概要は準備中です。原文の説明を表示しています。

Execute story implementation following a context filled story spec file. Use when the user says "dev this story [story file]" or "implement the next story in the sprint plan"

日本語の概要は準備中です。原文の説明を表示しています。

Technical documentation specialist and knowledge curator. Use when the user asks to talk to Bri or requests the tech writer.

日本語の概要は準備中です。原文の説明を表示しています。

Compile your local stellar-build usage traces into sharper skills. Use when the user says "optimize my skills", "optimize-skills", "improve my skills from usage", "learn from my traces", "stellar-loop optimize", or wants the learning loop to refine installed skills based on how they've actually been used. DSPy-style prompt optimization over the local trace store at ~/.stellar-build/traces — fully local, reversible.

日本語の概要は準備中です。原文の説明を表示しています。

Product manager for PRD creation and requirements discovery. Use when the user asks to talk to Nicole or requests the product manager.

日本語の概要は準備中です。原文の説明を表示しています。

Review code changes adversarially using parallel review layers (Blind Hunter, Edge Case Hunter, Acceptance Auditor) with structured triage into actionable categories. Use when the user says "run code review" or "review this code"

日本語の概要は準備中です。原文の説明を表示しています。

Forensic case investigation with evidence-graded findings, calibrated to the input. Use when the user asks to investigate a bug, trace what caused an incident, walk through unfamiliar code, or build a mental model of a code area before working on it.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes current state and user query to answer BMad questions or recommend the next skill(s) to use. Use when user asks for help, bmad help, what to do next, or what to start with in BMad.

日本語の概要は準備中です。原文の説明を表示しています。

Walk every branching path and boundary condition in content, report only unhandled edge cases. Orthogonal to adversarial review - method-driven not attitude-driven. Use when you need exhaustive edge-case analysis of code, specs, or diffs.

日本語の概要は準備中です。原文の説明を表示しています。

Archive multiple completed changes at once. Use when archiving several parallel changes.

日本語の概要は準備中です。原文の説明を表示しています。

Sync delta specs from a change to main specs. Use when the user wants to update main specs with changes from a delta spec, without archiving the change.

日本語の概要は準備中です。原文の説明を表示しています。

Continue working on an OpenSpec change by creating the next artifact. Use when the user wants to progress their change, create the next artifact, or continue their workflow.

日本語の概要は準備中です。原文の説明を表示しています。

Enter explore mode - a thinking partner for exploring ideas, investigating problems, and clarifying requirements. Use when the user wants to think through something before or during a change.

日本語の概要は準備中です。原文の説明を表示しています。

Design system and premium UX rules for VenTu (ventu.surf). Use whenever building, restyling, reviewing, or polishing any frontend page, component, map, drawer, or motion. Overrides generic AI aesthetic defaults.

日本語の概要は準備中です。原文の説明を表示しています。

PT-PT voice and i18n rules for VenTu copy. Use whenever writing or editing user-facing strings, translations, news, or Dawn Patrol content.

日本語の概要は準備中です。原文の説明を表示しています。

Progressively activates todo tests one at a time, updates implementation code until each passes (verified via Wallaby), checks off matching design doc progress, then moves to the next—following the design doc as the single source of truth.

日本語の概要は準備中です。原文の説明を表示しています。

Runs Charted Coding iterations in a loop — route via charted-continue, batch red or green work for an entire test file, commit, then repeat until the PR is complete. Infers design doc and PR number when omitted. Use when the user invokes charted loop, wants batch TDD for a PR test file, or asks to continue charted work with commits.

日本語の概要は準備中です。原文の説明を表示しています。

TypeScript and test style conventions for the testmex monorepo. Use when writing or reviewing TypeScript types, interfaces, core domain models, or tests in this repository.

日本語の概要は準備中です。原文の説明を表示しています。