「asm」の検索結果

Knowledge base from the NASA Digital Engineering Acquisition Framework Handbook (NASA-HDBK-1004). Use for acquiring digital/model-based data under contract: the Data Requirements Description (DRD) instrument and the Appendix A DRD suite (TDP, MBx, CDMP, CSA, CR, FCA/PCA, SDT, EMDAL, REF, MRI); the Data Type 1-5 control scale; SOW/RFP/Cost-Volume contract language and data rights (FAR/DFARS, Table 3 license categories); the Requirements Exchange Format (REF/ReqIF, UUID schema) and Master Records Index; model-based data definition (MBSE, CAD/PMI, M&S credibility, BOM, release-state mapping, PLM); digital data collaboration, the four owned architectures, and interoperability standards (MIL-STD-31000, STEP/ISO 10303, ASME Y14); the four MBE interoperability use cases; and MBE Plan development. Scope is the acquisition and contracting side of digital engineering. Does not reproduce ISO/STEP/ASME/MIL-STD/SAE standard text, and the companion NASA-HDBK-1009A carries the deeper digital-engineering practitioner detail this handbook defers to.

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Backend Rust Specialist IA — Expert en développement backend Rust (Actix, Axum, Tokio, zero-cost abstractions, WASM)

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Rust 製フロントエンドフレームワーク fandhe-frontend のリファレンス。 SSR / SPA / SSG / View Transitions、hydration、単一実行ファイル配布、Vercel デプロイ、既定エスケープ。 クレート core / app / interactive / server(generate_pages) / headless-ui(Primitives) / pre-styled-ui(Themes, motion feature) / wireframe-ui(Wireframes) / animation(fandhe-animation, data-* 属性) / wasm-full(feature 選択)。 Blocks(Hero / Pricing / Cart 等セクション例 329 件)。CLI fw。

Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT for T2T), extracting contigs from GFA and routing phasing QC to k-mer/trio metrics. Covers why a primary assembly is a haplotype mosaic that exists in no cell, partial-vs-full phasing (the .bp. vs .dip. filename convention), the purge-default trap on inbred samples, the --hom-cov coverage-estimate alarm, and verkko-vs-hifiasm for T2T. Use when assembling a diploid eukaryote from HiFi, phasing haplotypes with parents (trio) or Hi-C, deciding whether to chase T2T, or diagnosing switch errors invisible to N50/BUSCO/QV.

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Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why N50 is the most-gamed metric, why QV measured on the polishing reads is circular, distinguishing uncollapsed haplotigs from real WGD, and the EBP/VGP 6.C.Q40 standard. Use when judging whether an assembly is good enough to annotate or publish, comparing assemblers, diagnosing a fragmented or duplicated assembly, or assessing a phased diploid assembly.

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Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

日本語の概要は準備中です。原文の説明を表示しています。

Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why N50 is the most-gamed metric, why QV measured on the polishing reads is circular, distinguishing uncollapsed haplotigs from real WGD, and the EBP/VGP 6.C.Q40 standard. Use when judging whether an assembly is good enough to annotate or publish, comparing assemblers, diagnosing a fragmented or duplicated assembly, or assessing a phased diploid assembly.

日本語の概要は準備中です。原文の説明を表示しています。

Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT for T2T), extracting contigs from GFA and routing phasing QC to k-mer/trio metrics. Covers why a primary assembly is a haplotype mosaic that exists in no cell, partial-vs-full phasing (the .bp. vs .dip. filename convention), the purge-default trap on inbred samples, the --hom-cov coverage-estimate alarm, and verkko-vs-hifiasm for T2T. Use when assembling a diploid eukaryote from HiFi, phasing haplotypes with parents (trio) or Hi-C, deciding whether to chase T2T, or diagnosing switch errors invisible to N50/BUSCO/QV.

日本語の概要は準備中です。原文の説明を表示しています。

Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

日本語の概要は準備中です。原文の説明を表示しています。

Implement state machines with AASM for workflow management. Covers state transitions, guards, callbacks, and testing.

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GPU-accelerated terminal emulator with AI-native and Web3-native features built on wgpu+WASM.

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Compiles .NET to WebAssembly AOT. Blazor/Uno WASM, size vs speed, lazy loading, Brotli.

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Review native registration or external Wasm plugin trust boundaries.

日本語の概要は準備中です。原文の説明を表示しています。

Run the smallest relevant core, Wasmtime, HAP, or full Homecore test profile.

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Format chat messages in a local model's template (llama3, mistral, chatml, phi, gemma, or a model id) and route queries over a small WASM HNSW pattern index (about 11 patterns). Use when preparing prompts for local runtimes.

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Apply a simple code transform via agent-booster's WASM engine — sub-millisecond, deterministic, $0 (no LLM call). Companion to cost-booster-route.

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Vector search via embeddings_* (large-scale HNSW) and ruvllm_hnsw_* (WASM router for ≤11 hot patterns), with RaBitQ 1-bit quantization for 32× memory reduction

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Run an Anthropic Claude Managed Agent — a cloud agent harness (container + filesystem + tools), the cloud counterpart of the local wasm-agent runtime

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Provides reverse engineering techniques. Use when the main job is to understand how a compiled, obfuscated, packed, or virtualized target works before exploiting or solving it, including binaries, APKs, WASM, firmware, custom VMs, bytecode, malware-like loaders, and anti-debug or anti-analysis logic. Do not use it when the vulnerability is already understood and the remaining task is exploitation; use pwn instead. Do not use it for pure web workflows, log or disk forensics, or standalone crypto problems unless reversing the implementation is the real blocker.

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Reverse JavaScript-based custom DSL/VM interpreters, non-standard WASM-like runtimes, and risk-control engines. Use when analyzing IIFE or switch-based opcode dispatchers, extracting instruction tables, recovering bytecode semantics, capturing VM state at runtime, or reconstructing execution flow.

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Use when writing or modifying real-browser Playwright E2E / functional tests for Handsontable (specs in tests/e2e/, core, wrappers, or walkontable). Covers the Page Object Model, hooking in by data-testid, deterministic web-first waits, wrapper-specific gotchas, recording via the CLI, and the new-vs-modify / E2E-vs-unit decision. NOT for screenshot/visual tests (use visual-testing) or the legacy Jasmine suite (use handsontable-e2e-testing).

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Use ONLY when maintaining the FROZEN legacy Jasmine/Puppeteer E2E suite (*.spec.js) – editing an existing spec, or migrating a broken one to Playwright. NOT for new E2E: new E2E is Playwright, use the `handsontable-playwright-e2e` skill. Covers the legacy boilerplate, async/await rules, global helpers, event simulation, and theme-agnostic assertions.

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Generate, regenerate, and validate 2D DXF drawings from Python build123d sources. Use for DXF files, `.py` drawing scripts, @dxf models, 2D profiles, outlines, templates, gaskets, panels, flat patterns, laser/plasma/waterjet cut layouts, and 2D drawing exports of CAD geometry. Open and visually review existing DXF files in CAD Viewer.

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WebAssembly expert for WASI, component model, Rust/C compilation, and browser integration

日本語の概要は準備中です。原文の説明を表示しています。