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概要と使いどころ
Implements HIPAA minimum necessary standard under 45 CFR §164.502(b). Covers role-based access policies per workforce member category, routine vs non-routine disclosure protocols, reasonable reliance doctrine, documentation requirements, and HITECH amendments. Keywords: minimum necessary, role-based access, workforce, routine disclosure, HIPAA.
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Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
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Proteina-Complexa flow-based protein backbone generation with fold-conditioned sampling guidance. Use this skill when: (1) Generating de novo protein backbones with hierarchical fold conditioning, (2) Exploring long-chain backbone generation beyond standard diffusion baselines, (3) Using NVIDIA Proteina-style flow matching workflows for controllable backbone design, (4) Comparing flow-based backbone generation against RFdiffusion or BoltzGen, (5) Prototyping fold-guided backbone campaigns before sequence design. This skill is based on the public NVIDIA Digital Bio Proteina project and uses "Proteina-Complexa" as the BioClaw-facing skill label. For sequence design after backbone generation, use proteinmpnn or solublempnn. For QC thresholds, use protein-design-qc.
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Produce a multi-quarter QA strategy document. Covers scope, risk-based prioritization, test levels (unit/integration/E2E), pyramid analysis, entry/exit criteria, quality KPIs, tool selection rationale, CI scaling levers, and timeline planning. Output is an actionable strategy document, not a shelf document. Use when: "test strategy," "QA strategy doc," "testing approach," "QA roadmap," "multi-quarter QA direction." Not for: a single-sprint or single-release plan — use test-planning. Not for: identifying which areas carry the most risk — use risk-based-testing first. Related: risk-based-testing, qa-metrics, release-readiness, test-planning, test-reliability.
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Design and execute structured exploratory testing sessions. Covers Session-Based Test Management (SBTM), charter writing, heuristic-based exploration (HICCUPS, FEW HICCUPS), bug discovery patterns, note-taking templates, and conversion of findings to automated tests. Use when: "exploratory testing," "SBTM," "manual testing," "bug hunting," "test charter," "heuristic testing." Not for: an AI browser agent autonomously exploring the app from a natural-language goal — use agentic-browser-testing. Not for: testing your product's own AI/LLM features — use ai-system-testing. Related: test-planning, ai-bug-triage, risk-based-testing, agentic-browser-testing.
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Git is deceptively simple to learn and incredibly hard to master. The difference between a team that ships and a team that fights merge conflicts all day comes down to workflow discipline. Your git history is documentation - make it tell a story future you can understand. This skill covers branching strategies (trunk-based, gitflow, GitHub flow), commit hygiene, merge vs rebase, conflict resolution, and the commands you actually need. Key insight: most git disasters come from not understanding what you're about to do. 2025 lesson: Trunk-based development with short-lived branches has won. Long-lived feature branches are a code smell. If a branch lives more than a few days, something is wrong with your architecture or process. Use when "git workflow, branching strategy, git merge, git rebase, merge conflict, git commit, trunk-based, gitflow, git history, git revert, git reset, git, version-control, workflow, branching, commits, merge, rebase, collaboration" mentioned.
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When the user wants to perform load testing or performance testing using Artillery with YAML-based scenario definitions. Also use when the user mentions "artillery," "YAML load test," "WebSocket testing," "Socket.io load test," "scenario-based load testing," or "artillery run." For JavaScript-based load testing, see k6.
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Azure AI Hosted Agents (Python) workflow skill. Use this skill when the user needs Build container-based Foundry Agents with Azure AI Projects SDK (ImageBasedHostedAgentDefinition). Use when creating hosted agents with custom container images in Azure AI Foundry and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.
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中医诊疗 — 中医临床医师的认知操作系统 (经典理论 阴阳五行脏腑气血经络六经卫气营血三焦 + 四诊八纲 + 治法 + 方剂学 经方时方 + 中药学 四气五味归经炮制 + 针灸学 经络穴位手法灸法 + 推拿按摩 + 中医各科 内外妇儿骨伤皮肤眼耳鼻喉肛肠老年急症 + 中西医结合 + 循证中医 + NATCM 监管 + 中医诊所备案 + 国家级名老中医 学术继承人 — 不含 道家修炼 / 风水算命 / 中医养生科普 / 中医美容 / 民族医学藏蒙维傣) (Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注).) Master OS — automated mastery of Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注).: top builders' mental models, tool stack, current workflows, jargon, and where to keep up. Trigger this skill when the user works on Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注). problems and wants industry-grade thinking, tool selection, or workflow guidance. 触发词：「中医」「中医学」「中医药」「中医诊疗」「中医临床」
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健身私教 — 为客户设计、指导和推进个性化训练方案的专业工艺, 有别于团课教练、物理治疗师或运动队教练: (a) 训练方案设计与周期化 (线性 / 波动 / 板块周期化 Bompa & Haff; NSCA《力量训练与体能训练精要》行业圣经; Schoenfeld 肌肥大机制; Helms/Valdez/Morgan 肌肉与力量金字塔; 共轭训练法 Simmons/Westside; Starting Strength 线性渐进 Rippetoe; Renaissance Periodization 训练量地标 Israetel); (b) 动作评估与筛查 (FMS 功能性动作筛查 Gray Cook; NASM CEx 纠正性训练连续体 抑制-拉伸-激活-整合; 关节逐级方法 Cook/Boyle; 姿势与代偿模式识别; PAR-Q+ 与 ACSM 运动前筛查指南); (c) 教学与指令 (外部 vs 内部注意焦点 Wulf; 差异化学习 Schöllhorn; 约束导向方法 Davids/Renshaw; RIR/RPE 自动调节 Zourdos/Helms; 动机访谈在健身中的应用 Rollnick/Miller); (d) 营养指导的执业边界 (宏量营养素周期化; Precision Nutrition / ISSN 立场声明的循证建议; 边界: 私教提供一般性指导, 医学营养治疗需 RD/RDN 资质; 能量可用性与 RED-S Mountjoy IOC 共识); (e) 商业与客户管理 (客户留存与方案依从; 咨询与销售伦理; 线上教练平台与规模化 Goodman PTDC; 方案交付工具 TrueCoach/Trainerize/TrainHeroic; 课时定价模型; 独立教练 vs 健身房雇员); (f) 专项方向 (运动表现 CSCS; 纠正性训练 CES; 老年健身 SFN; 产前产后; 青少年 YSCA; 适应性 / 无障碍健身; 健美 / 形体; 力量举; 耐力运动 S&C)。诚实处理: 兄弟科学 vs 循证之争, 补剂行业利益冲突, 合成代谢激素使用现状 (诚实但不推广: 匿名调查约 30% 有经验男性健身者使用过 — 业内估, Kanayama/Pope/Hudson 记录健康风险, WADA 禁用清单用于竞技语境), 体型焦虑与进食障碍风险 (男性私教肌肉变形症, 正食症倾向, NEDA 负责任语言指南), 健身房掠夺性销售 (高压推销、误导性对比照、长约锁定), 执业边界违规 (私教诊断伤病或超范围开饮食处方), 线上教练认证造假 (周末速成、未经认可的认证)。不含: 物理治疗 / 康复治疗 (持照医疗职业), 不含: 团课教练 (Les Mills/Zumba/CrossFit 分馆教练 — 相邻但不同), 不含: 精英竞技运动教练 (团队项目周期化, 不同职业路径), 不含: 营养作为主业 (临床营养学需单独资质)。 (Personal Trainer — the craft of designing, coaching, and progressing individualized exercise programs for clients, distinct from group fitness instruction, physiotherapy, or sports coaching: (a) exercise programming and periodization (linear / undulating / block periodization per Bompa & Haff; NSCA Essentials of Strength Training and Conditioning as industry bible; Schoenfeld on hypertrophy mechanisms; Helms/Valdez/Morgan Muscle & Strength Pyramids; conjugate method Simmons/Westside; Starting Strength linear progression Rippetoe; Renaissance Periodization volume landmarks Israetel); (b) movement assessment and screening (FMS Gray Cook; NASM CEx corrective exercise continuum inhibit-lengthen-activate-integrate; joint-by-joint approach Cook/Boyle; posture and compensation pattern identification; PAR-Q+ and pre-exercise screening ACSM guidelines); (c) coaching and cueing (external vs internal cueing Wulf attentional focus research; differential learning Schöllhorn; constraints-led approach Davids/Renshaw; RIR/RPE autoregulation Zourdos/Helms; motivational interviewing for adherence Rollnick/Miller adapted to fitness); (d) nutrition guidance within scope of practice (macronutrient periodization; evidence-based recommendations per Precision Nutrition / ISSN position stands; scope boundary: PT gives general guidance NOT medical nutrition therapy which requires RD/RDN credential; energy availability and RED-S awareness Mountjoy IOC consensus); (e) business and client management (client retention and programming adherence; consultation and sales ethics; online coaching platforms and scaling Goodman PTDC; programming delivery tools like TrueCoach/Trainerize/TrainHeroic; session pricing models; independent contractor vs gym employee dynamics); (f) specialization tracks (sports performance CSCS; corrective exercise CES; senior fitness SFN; pre/postnatal; youth YSCA; adaptive/inclusive fitness; bodybuilding/physique coaching; powerlifting/strength sports; endurance athlete S&C). Evidence-based practice as the core ethos: Schoenfeld/Krieger meta-analyses on volume-response, Helms systematic reviews on protein/resistance training, Brad Schoenfeld's MASS journal bridging research to practice, Menno Henselmans and Eric Helms as practitioner-researchers, Greg Nuckols Stronger By Science as translation layer. Chinese fitness industry context: rapid growth of personal training in commercial gyms (Keep/Lefit/Megafit chains), NSCA-CPT and ACE-CPT as dominant certifications alongside local CSFA (China Sport and Fitness Association) credential, '体适能' (physical fitness) as formal term, online coaching boom post-COVID, PT business models in tier 1-3 cities diverge sharply. Honest treatment of: bro science vs evidence-based d
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Anchor a multidisciplinary unit in a real-world phenomenon that requires multiple subject lenses to understand. Use when designing integrated or phenomenon-based units across disciplines.
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Present pathway options and orchestrate place-based curriculum design from a local place, curriculum requirement, or community issue. Use when place should become a primary text for learning.
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Amazon product discovery and potential bestseller mining via Nexscope data. Triggered when users mention product mining, potential bestsellers, high-conversion product selection, click growth analysis, market growth opportunities, keyword-based product selection, FBA profit screening, niche market product discovery, seller origin filtering, Nexscope data, FBA profitability screening, keyword-based product selection. Even if users do not explicitly mention "Nexscope", this skill should be triggered whenever the task involves keyword-driven Amazon product selection based on conversion rates, click volume, and profitability metrics.
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Configure Kubernetes Ingress networking with NGINX Ingress Controller, cert-manager for automated TLS certificate management, path-based routing, rate limiting, and multi-domain hosting with SSL termination and load balancing. Use when exposing multiple Kubernetes services via a single load balancer, implementing path-based or host-based routing, automating TLS certificate issuance with Let's Encrypt, or setting up blue-green and canary deployments with traffic splitting.
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Implement activity-based costing systems. TRIGGERS - Use when user needs help with activity-based-costing related tasks.
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"Implement content-based recommendation by matching item features to user preference profiles. Use this skill when the user needs to recommend items based on attributes, solve the cold start problem for new items, or build recommendations without collaborative data — even if they say 'recommend similar products', 'items like this', or 'feature-based matching'.".
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Detect and exploit SQL injection vulnerabilities using both manual techniques and automated tools. Use this skill when testing web applications for database injection flaws including UNION-based, error-based, blind boolean, blind time-based, and out-of-band SQL injection. Covers WAF bypass, second-order SQLi, authentication bypass, and full database extraction with sqlmap.
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Audit public sector and government resource allocation systems for budget optimization algorithms (zero-based, incremental, performance-based), service demand forecasting (ARIMA, Prophet, regression), equity-based distribution scoring (CDC SVI, environmental justice indices.
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Usage-based pricing in Revenue Cloud: metered billing, usage records, rating, tiering, consumption schedules. NOT for choosing a CPQ pricing method (List, Block, Cost Plus Markup, Percent of Total) - use admin/pricing-model-design. NOT for legacy Salesforce Billing (blng__) schedules and invoice runs - use admin/billing-schedule-setup.
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Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
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Build container-based Foundry Agents using Azure AI Projects SDK with ImageBasedHostedAgentDefinition. Use when creating hosted agents that run custom code in Azure AI Foundry with your own container images. Triggers: "ImageBasedHostedAgentDefinition", "hosted agent", "container agent", "Foundry ...
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Configures host-based intrusion detection systems (HIDS) to monitor endpoint file integrity, system calls, and configuration changes for security violations. Use when deploying OSSEC, Wazuh, or AIDE for endpoint monitoring, building file integrity monitoring (FIM) policies, or meeting compliance requirements for change detection. Activates for requests involving HIDS configuration, file integrity monitoring, OSSEC/Wazuh deployment, or host-based detection.
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Configures host-based intrusion detection systems (HIDS) to monitor endpoint file integrity, system calls, and configuration changes for security violations. Use when deploying OSSEC, Wazuh, or AIDE for endpoint monitoring, building file integrity monitoring (FIM) policies, or meeting compliance requirements for change detection. Activates for requests involving HIDS configuration, file integrity monitoring, OSSEC/Wazuh deployment, or host-based detection.
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Identify drug repurposing candidates via target-based, compound-based, and disease-based strategies. Combines drug-target-disease network reasoning with mechanism rationale, clinical-trial precedent, and patent/regulatory feasibility. Use for hypothesis-generating repurposing for orphan diseases, finding existing drugs for new indications, and prioritizing candidates by evidence and feasibility.
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