「functional」の検索結果

Engineering design cycle covering requirements elicitation, specifications writing, constraint identification, iterative prototyping, and design communication. Spans the full loop from problem definition through ideation, analysis, prototyping, testing, and redesign. Includes morphological charts, TRIZ, Pugh matrices, design reviews, and the distinction between functional and non-functional requirements. Use when framing engineering problems, generating design alternatives, writing specifications, or running design reviews.

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Carbon chemistry, functional groups, IUPAC nomenclature, isomerism, reaction mechanisms (substitution, elimination, addition), polymers, and biochemistry basics. Covers hydrocarbon classes (alkanes, alkenes, alkynes, aromatics), common functional groups (alcohols, aldehydes, ketones, carboxylic acids, esters, amines, amides), stereochemistry, condensation and addition polymerization, and the four biomolecule classes (carbohydrates, lipids, proteins, nucleic acids). Use when analyzing organic structures, predicting reaction products, or connecting chemistry to biology.

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Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser screenshots, and viewing browser logs. Use when the task involves `test web application`, `test frontend`, `browser testing`, `Playwright test`, `capture browser screenshot`, `debug UI behavior`, or `verify frontend functionality`.

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Elixir and Phoenix expert including OTP, Ecto, and functional programming

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Reorganize label-heavy or netlist-like electronic schematics into human-readable functional diagrams with visible local wiring while preserving proven connectivity. Use for schematic readability correction, overlapping wires or symbols, visually floating connectors or support logic, functional-sheet restructuring, bus presentation, layout annotations, or multi-EDA handoff across KiCad, Altium, EasyEDA, EAGLE/Fusion, gEDA/Lepton, SPICE/netlist, and PDF/image sources.

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Auto-activates when analyzing GitHub issues to extract functional requirements, non-functional requirements, acceptance criteria, and user stories.

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Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact on regulatory elements, perform enrichment testing of variant sets in tissue-specific annotations, or link variants to target genes through enhancer-gene maps. Handles the full post-GWAS workflow from variant set → tissue mapping → functional annotation → fine-mapping awareness → enrichment → variant-to-gene → prioritization. Use this skill for ANY variant interpretation task involving ENCODE chromatin, accessibility, TF binding, or 3D genome data.

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Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify chromatin states with ChromHMM, identify super-enhancers with ROSE, understand the functional validation hierarchy (CRISPR > MPRA > reporter), or characterize non-coding genomic regions. Covers the full workflow from ENCODE cCRE lookup through chromatin state segmentation to functional validation and enhancer-gene linkage. Use this skill for ANY regulatory element discovery, classification, or characterization task.

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Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models, cross-reference with clinical trials and drug databases, or conduct any disease-focused, pathology-driven, or clinical variant interpretation workflow. Covers the full pipeline from disease-tissue mapping through GWAS variant annotation, heritability enrichment, cancer epigenomics, drug target identification, and clinical trial cross-referencing. Integrates ENCODE with Open Targets, PubMed, ClinicalTrials.gov, and bioRxiv.

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Eliciting, documenting and structuring requirements for a Salesforce implementation: stakeholder discovery interviews, As-Is and To-Be process mapping, and gap analysis against standard Salesforce capability. Trigger keywords: requirements gathering, user story, As-Is To-Be, gap analysis, stakeholder interview, process mapping, business requirements, fit gap. NOT for authoring the user stories themselves - use admin/user-story-writing-for-salesforce. NOT for scoring requirements against a specific org - use admin/fit-gap-analysis-against-org. NOT for technical design decisions - use architect/solution-design-patterns. Also covers the requirements catalogue itself (one row per requirement, MoSCoW priority, source stakeholder, downstream target) and Salesforce non-functional requirements: record volume, sharing layer, integration pattern, reporting joins, mobile/offline, and licence implication.

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Structural and functional brain connectivity — tractography, functional networks, and graph-theoretic analysis.

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Estimates SNP heritability and partitions it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

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Expert-level organic chemistry knowledge. Use when working with organic reactions, mechanisms, functional groups, stereochemistry, synthesis planning, spectroscopy, or named reactions. Also use when the user mentions 'organic reaction', 'mechanism', 'functional group', 'stereochemistry', 'synthesis', 'NMR', 'IR spectroscopy', 'SN1', 'SN2', 'elimination', 'addition', 'aromatic', 'carbonyl', or 'named reaction'.

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Produce a release test-impact analysis for a Tamanu version upgrade: compare two Tamanu releases and classify every functional area as Full Test, Smoke Test, or Skip, each with a short reason and the Linear card or PR reference. Use when the user wants a test plan, QA scope, regression scope, or "what to test" for a Tamanu release or upgrade, wants to compare or diff two Tamanu versions (e.g. v2.57 to v2.59), or asks which areas changed between two releases. Handles Tamanu's train-release model (release/X.Y branches vs vX.Y.Z tags) and maps changed files and PRs to Tamanu functional sections (Patient Management, Encounters/Charting, Surveys & Programs, Medications, Labs, Imaging, Appointments, Vaccinations, Sync, Settings, Reports, Admin/Permissions, Mobile, etc.). Optionally maps against a regression-testing spreadsheet's sections when one is provided.

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METAINFORMANT rules for directory src/metainformant/metagenomics/functional. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.

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Implement functional Clawix UI wiring while respecting visual mutation boundaries, pattern contracts, protected surfaces, and debt baselines.

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Turns a business need and its constraints into a DRAFT RFP requirements pack: traced functional and non-functional requirements with priorities, mandatory gates, evaluation criteria with weights left to the business owner, and fact-seeking supplier questions. Solution-neutral; never names a supplier or product. Use when the user asks to "write the RFP requirements", "turn this business case into tender requirements", "draft the supplier questionnaire", "structure our RFQ from this brief" or "set up evaluation criteria before we go to market". Do not use for responses already received, use rfp-comparison-pack to compare them or supplier-evaluation-matrix to score them instead. Drafts for human review; never approves, authorises or signs off.

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Functional error handling in Dart using the fpdart package with Either, Option, TaskEither, and Do notation. Use when replacing try-catch with type-safe error handling or composing async operations functionally.

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End-to-end shotgun metagenomics workflow from FASTQ to taxonomic and functional profiles, orchestrating controls/host depletion, Kraken2+Bracken classification, MetaPhlAn marker profiling, and HUMAnN functional profiling. Covers the controls-first ordering, why Kraken2 read counts are not abundances and MetaPhlAn cell fractions do not equal Bracken read fractions, and the consistent-pipeline framing. Use when profiling shotgun metagenomic samples end to end, or chaining classification, abundance, and function. For resistome see metagenomics/amr-detection; for strains see metagenomics/strain-tracking; for assembly see genome-assembly/metagenome-assembly.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Uncorrelated Evaluator — 4軸ルーブリック専門エージェント（functionality-reviewer・code-reviewer・design-reviewer・originality-reviewer）と security-reviewer を5並列実行し、成果物を多面的に独立評価します。PASS / NEEDS WORK / BLOCKED 判定を返します。Self-leniency 防止のため、実装エージェントのコンテキストを引き継がない新規エージェントとして起動します。「レビューして」「評価して」「実装を確認して」などのリクエストで起動します。

Design traceable functional test conditions across positive, negative, boundary, and error behavior with observable expectations.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

新しい機能や企画を作り始める前に、対話で目的や希望、制約を整理します。必要に応じて図や試作品で認識を確かめ、作業の規模に合った設計をまとめるスキルです。

• 新機能の目的を明確にしたいとき
• 講演や事業のアイデア整理
• 画面や部屋の配置を見比べたいとき