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Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

日本語の概要は準備中です。原文の説明を表示しています。

Design engineering principles for making interfaces feel polished. Use when building UI components, reviewing frontend code, implementing animations, hover states, shadows, borders, typography, icons, micro-interactions, enter/exit animations, or any visual detail work. Supports quick and full review modes. Triggers on UI polish, design details, "make it feel better", "feels off", stagger animations, border radius, optical alignment, font smoothing, tabular numbers, image outlines, box shadows, icons, icon stroke weight, icon states, motion restraint.

日本語の概要は準備中です。原文の説明を表示しています。

豆包 / 微信输入法个人词库：识别、导出、导入、备份；纠错优化； 搜索并生成行业/专业/定制词库（并入归档 industry-dict）。 不走官方导入页。搜索优先 argo，没有就走通用搜索兜底。本技能只出查询、抽词、改表、写回副本。 生态定位：直接操作豆包 / 微信输入法词库文件层（usr.dat / WeType LevelDB）的 agent skill， 文件层识别、批量导出、槽位感知注入、整表替换消错、行业词库造词后直接 apply； 格式互转工具和语音输入插件都不做词库管理。 触发：个人词库、词库导出、词库导入、反向注入、行业词库、专业词库、定制词库、 生成行业词库、做词库、行业术语、industry-dict、拼写纠正、豆包词库、 微信输入法词库、WeType、usr.dat、ime-lexicon、/ime-lexicon

日本語の概要は準備中です。原文の説明を表示しています。

Windows アプリ開発 (Fluent Design / WinUI 3) の デザインガイドラインリファレンス。 layout, spacing, alignment, elevation, geometry, breakpoints, Color, Mica, Acrylic, Smoke, Reveal Highlight, materials, typography, Segoe Fluent Icons, app icons, motion, easing, connected animation, page transitions, parallax, reduce motion, NavigationView, TabView, CommandBar, menus, keyboard accelerators, access keys, accessibility, high contrast, RTL, globalization, widgets design。

Android Jetpack Compose (Kotlin) の androidx Material3 コンポーネントリファレンス。 Button, IconButton, FloatingActionButton, Checkbox, Switch, Slider, TextField, SearchBar, DropdownMenu, Chip, DatePicker, TimePicker, Card, Scaffold, Dialog, BottomSheet, TopAppBar, NavigationBar, NavigationRail, Tab, Snackbar, ProgressIndicator, Badge, Icon, MaterialTheme, ColorScheme, Typography, Shapes。

Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

日本語の概要は準備中です。原文の説明を表示しています。

Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

日本語の概要は準備中です。原文の説明を表示しています。

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

日本語の概要は準備中です。原文の説明を表示しています。

Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

日本語の概要は準備中です。原文の説明を表示しています。

Next.js route metadata, per-route favicons, OpenGraph, and Twitter cards. Use when adding a route or layout, adding a favicon or social share image, auditing missing metadata, naming tab titles, or touching createRouteMetadata, createDynamicRouteMetadata, generateFaviconMetadata, or titlePrefix.

日本語の概要は準備中です。原文の説明を表示しています。

Migrating custom icon buttons to TapButtons. Use when replacing a raw <button>, IconButton, or className-styled icon; migrating header, toolbar, or footer icons; lazy-splitting a button's highlight decoration; or on 'tap targets', 'efficiency update', 'lazy split', or making a small component production-ready.

日本語の概要は準備中です。原文の説明を表示しています。

Create or review icons for Kilo's VS Code extension, webviews, and shared icon registry.

日本語の概要は準備中です。原文の説明を表示しています。

Modern, clean UI/UX guidance + review skill. Use when you need actionable UX/UI recommendations, design principles, or a design review checklist for new features or existing systems (web/app). Focus on CRAP (Contrast/Repetition/Alignment/Proximity) plus task-first UX, information architecture, feedback & system status, consistency, affordances, error prevention/recovery, and cognitive load. Enforce a modern minimal style (clean, spacious, typography-led), reduce unnecessary copy, forbid emoji as icons, and recommend intuitive refined icons from a consistent icon set.

日本語の概要は準備中です。原文の説明を表示しています。

Specify an icon system — grid, sizing, stroke weight, naming, categories, and implementation. Use when standardising iconography. For broader illustration, use `illustration-style` (ui-design).

日本語の概要は準備中です。原文の説明を表示しています。

Build modern full-stack web applications with Next.js (App Router, Server Components, RSC, PPR, SSR, SSG, ISR), Turborepo (monorepo management, task pipelines, remote caching, parallel execution), and RemixIcon (3100+ SVG icons in outlined/filled styles). Use when creating React applications, implementing server-side rendering, setting up monorepos with multiple packages, optimizing build performance and caching strategies, adding icon libraries, managing shared dependencies, or working with TypeScript full-stack projects.

日本語の概要は準備中です。原文の説明を表示しています。

Generate AI images using Gemini or GPT APIs directly. Covers model selection (Gemini for scenes; GPT Image 2 for text rendering, batch variations, multi-reference compositing; GPT Image 1.5 for transparent icons), the 5-part prompting framework, API calling patterns, multi-turn editing, and quality assurance. Produces photorealistic scenes, icons, illustrations, OG images, posters, infographics, and product shots. Use when building websites that need images, creating marketing assets, or generating visual content. Triggers: 'generate image', 'ai image', 'create hero image', 'make an icon', 'generate illustration', 'create og image', 'poster', 'infographic', 'image variations', 'gpt-image-2', 'ai art', 'image generation'.

日本語の概要は準備中です。原文の説明を表示しています。

Design or evaluate a brand visual identity system covering logo, color, typography, imagery direction, iconography, and motion principles. Use this skill whenever the user wants to design a logo, build a visual identity, define brand colors, choose brand typography, develop iconography, plan brand imagery, or evaluate an existing identity for cohesion. Triggers on logo design, brand identity, visual identity, brand mark, wordmark, monogram, color palette, brand colors, brand typography, type system, iconography, brand imagery, motion design, brand system, identity system. Also triggers when the user has a brand direction approved and now needs the visual artifacts that express it.

日本語の概要は準備中です。原文の説明を表示しています。

Image processing toolkit awareness. Use when: user uploads images for manipulation, requests format conversion, batch processing, compositing, resizing, optimization, analysis, effects, metadata inspection, montages, animated GIFs, color correction, or any image-related task. Also use when working with screenshots, photos, diagrams, icons, or visual assets. Triggers on 'resize', 'crop', 'convert', 'compress', 'optimize', 'thumbnail', 'watermark', 'montage', 'collage', 'gif', 'sprite sheet', 'color space', 'metadata', 'EXIF', 'compare images', 'diff', 'overlay', 'composite', 'batch process', 'image analysis', 'histogram', 'blur', 'sharpen', 'rotate', 'flip', 'border', 'shadow', 'round corners', 'favicon', 'icon set'.

日本語の概要は準備中です。原文の説明を表示しています。

Generate clean, playful low-density isometric voxel icon illustrations and explicitly requested four-frame physically credible loops built from large opaque face-lit acrylic blocks on an exact

日本語の概要は準備中です。原文の説明を表示しています。

Search free commercial-use creative assets across multiple online sources — photos, illustrations, icons, video footage, music, sound effects, and fonts. Use when the user needs to find assets for videos, PPTs, articles, or any content creation. Trigger on phrases like "find me a photo of", "search for icons", "I need background music", "find video footage", "search fonts", "找一张图片", "搜素材", "帮我找图标/视频/音乐/字体". Covers Pexels, Unsplash, Pixabay, Iconify, Freesound, Google Fonts and more — with API-backed search where available.

日本語の概要は準備中です。原文の説明を表示しています。

Create R-based pictogram glyphs for skill, agent, or team icons in the visualization layer. Covers concept sketching, ggplot2 layer composition using the primitives library, color strategy, registration in the appropriate glyph mapping file and manifest, rendering via the build pipeline, and visual verification of the neon-glow output. Use when a new entity has been added and needs a visual icon for the force-graph visualization, an existing glyph needs replacement, or when batch-creating glyphs for a new domain.

日本語の概要は準備中です。原文の説明を表示しています。

Generate NowStack Mobile onboarding backgrounds, splash, and brand artwork with AI image generation. Use for "generate onboarding images", "make brand art", "redo the splash". REQUIRES an image-gen tool (Codex/gpt-image); other agents follow the fallback. For the app icon (iOS/Android launcher icon) use ns-icon instead.

日本語の概要は準備中です。原文の説明を表示しています。