「ising model」の検索結果

Use when designing or revising a company's commercial policy — the rules of engagement governing discounts off list price, approver thresholds, exception flows, and the deal framework that Deal Desk and AEs operate under. Covers discount matrix design (ARR band x term length x payment terms x strategic value), commercial policy design, exception policy, discount governance, approval thresholds, deal framework structure, and policy linting (contradictions, gaps, cliff edges, gaming surfaces). For Head of Commercial, Head of Deal Desk, VP Sales, or RevOps at the policy-design moment — NOT per-deal application (that is deal-desk) and NOT pricing model selection (that is pricing-strategist).

日本語の概要は準備中です。原文の説明を表示しています。

Chief Data Officer advisory for startups: AI training data rights and consent provenance, data product strategy (warehouse vs lakehouse vs mesh, build-vs-buy), B2B customer-data-as-asset valuation and M&A readiness, data team org evolution. Use when deciding whether to train models on customer data, choosing data architecture, valuing data for fundraising or M&A, sequencing data hires, or when user mentions CDO, chief data officer, data strategy, data mesh, lakehouse, training data, data product, data monetization, or customer data asset. NOT a tactical data engineering skill — strategic decisions only.

日本語の概要は準備中です。原文の説明を表示しています。

Design content structure, hierarchy, labelling, and the navigation model. Use when organising what exists. For the UI that exposes it use `navigation-patterns` (interaction-design); for user-generated grouping evidence use `card-sort-analysis` (design-research).

日本語の概要は準備中です。原文の説明を表示しています。

Turn a topic or finished script into a complete, publish-ready explainer video — led by an AI presenter from an authorized adult presenter image, or performed with no presenter in one of twelve explainer styles (nine visual styles and three narrative ones). Not for promos, ads, or footage montages. Use for new presenter or styled explainer videos and for continuing, revising, captioning, lip-sync repairing, or re-exporting an existing job. Use it whenever the user asks for 数字人口播 / 数字人讲解, for a 讲解视频 / 动画讲解 / 科普视频, asks which styles or templates are available (有哪些风格 / 看看风格 / 风格模板), or names one of the styles: 留白, 信号/科技感, 手帐/手绘, 立体书/纸艺, 波普漫画, 一镜到底/3D, 图纸与注脚, 黑板报, 黏土小城, 推演/动态图解, 案卷/调查复盘, 小剧场/生活场景. Keep model and provider selection capability-based and record the actual choices per job.

日本語の概要は準備中です。原文の説明を表示しています。

Half-hour television comedy craft (半小时情景喜剧/笑点力学/困境机器/多机位单机位格式) — merged from Evan S. Smith's Writing Television Sitcoms (premise-driven comedy in three levels, nine predicaments, six character mixes, setup/punchline mechanics, toppers, running gags, ten comedic nuances, format rules), Neil Landau's sitcom seven-step formula and comedy-room models, Richard Blum's act-length and set-count parameters, Phoebe Waller-Bridge's Fleabag scripts (direct address as a season-long device, six-episode skeleton), Pamela Douglas on dramedy, Kam Miller on complementary comic traits, and Jesse Armstrong on jokes carrying tragedy. Use when writing or fixing a sitcom episode or spec, raising joke density per page, designing a comic predicament that generates stories, choosing between multi-camera and single-camera format and page counts, structuring cold open/acts/tag, writing a half-hour pilot, running a comedy punch-up, or making a drama funny without shifting genre.

日本語の概要は準備中です。原文の説明を表示しています。

Use when revising prose, the abstract, or the introduction of an American Economic Journal: Macroeconomics (AEJ: Macro) manuscript for AEA house style and the broad-interest macro arc. Late-stage polish on framing and clarity; it does not fix identification, the model, or exhibits.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building or revising exhibits for an American Economic Journal: Macroeconomics (AEJ: Macro) manuscript — impulse-response figures, fan charts, model-fit overlays, and regression/moment tables — to AEA house standards and macro conventions. Formatting and clarity; it does not generate the underlying estimates.

日本語の概要は準備中です。原文の説明を表示しています。

Use when drafting or revising the prose of an AEJ: Economic Policy manuscript — especially the abstract and introduction — to translate causal estimates into a clear policy takeaway without overclaiming. Shapes the policy-first narrative and house style; it does not design identification or build the welfare model.

日本語の概要は準備中です。原文の説明を表示しています。

Use when revising an ACM CCS paper for a precise threat model, calibrated attack/defense claims, 12-page ACM sigconf compression, double-blind wording, adaptive-evaluation honesty, and the security house style that survives an adversarial SIGSAC program committee.

日本語の概要は準備中です。原文の説明を表示しています。

Normalize read-depth copy-ratio profiles and segment them into copy-number regions using circular binary segmentation (CBS, DNAcopy), hidden Markov models, HaarSeg, and fused-lasso methods. Covers GC-content, mappability, and replication-timing (wave-artifact) bias correction, panel-of-normals/PCA denoising, diploid-baseline centering, and algorithm selection by sequencing depth and event size. Use when choosing a segmentation algorithm, correcting depth bias, diagnosing oversegmentation or a mis-centered baseline, tuning CBS or HMM parameters, or understanding why a downstream CNV caller produced fragmented or shifted segments.

日本語の概要は準備中です。原文の説明を表示しています。

Detects aberrant splicing in single rare-disease patients vs a control panel using FRASER 2.0 (Bioconductor; Beta-binomial autoencoder on Intron Jaccard Index, default delta cutoff 0.1, q hyperparameter), OUTRIDER (gene-level outlier expression via autoencoder denoising), LeafcutterMD (Dirichlet-multinomial outlier mode of LeafCutter for annotation-free junctions), and DROP (Snakemake pipeline integrating FRASER2 + OUTRIDER + monoallelic expression for clinical diagnostics). The statistical model is fundamentally different from differential splicing — single-sample-vs-cohort outlier detection rather than two-group comparison. Standard tool in EU rare-disease (Solve-RD) and NIH UDN programs. Use when applying RNA-seq to undiagnosed Mendelian disease, validating predicted splice variants in clinical samples, or detecting cryptic splicing in disease tissue.

日本語の概要は準備中です。原文の説明を表示しています。

Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes how multiple regulations interact for a specific product, service, or business model. Identifies where obligations overlap, reinforce, complement, duplicate, or conflict; builds a priority matrix; produces an integrated compliance timeline; and estimates the total compliance burden. Use when (1) scoping a new product or service against the full regulatory landscape before launch, (2) conducting M&A due diligence on a target's multi-regulation exposure, (3) building a strategic compliance roadmap where single-regulation analyses miss the interactions, (4) advising on complex situations where regulations touch the same conduct from different angles, or (5) estimating budget and resourcing for multi-regulation compliance. Primary coverage of EU digital regulation (GDPR, Data Act, AI Act, CRA, NIS2, DORA, DMA, DSA, ePrivacy) and national implementations; the framework extends to any jurisdiction where overlapping regulatory regimes apply to the same activity.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a result is surprising, impossible, contradicts a sanity check, a pipeline fails, a model won't converge, or a replication fails - before adjusting anything

日本語の概要は準備中です。原文の説明を表示しています。

Design and roll out a price increase or packaging change without triggering churn. Segments the base by price sensitivity, models revenue and churn scenarios, decides grandfathering and notice strategy, and produces the full comms kit (customer email, in-app notice, sales talk track, support FAQ, objection handling). Use when raising prices, repackaging tiers, or moving customers to new plans.

日本語の概要は準備中です。原文の説明を表示しています。

Design, implement, harden, and verify Model Context Protocol (MCP) servers with precise tool contracts, least-privilege authorization, safe transports, structured errors, and interoperability tests. Use when creating a new MCP server, exposing an API or data source through MCP, reviewing an MCP server design, adding or revising MCP tools, or preparing an MCP server for production.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when producing speech, narration, dubbing, localization, advertising voice, voice-clone previews, or interactive voice with MiniMax speech/audio APIs. It covers MiniMax T2A HTTP, WebSocket streaming, async long-form TTS, Speech 2.8/2.6/02 model selection, system and custom voices, rapid voice cloning, voice design, pronunciation/language/emotion controls, pricing and limits, artifact custody, consent and rights checks, and production QA.

日本語の概要は準備中です。原文の説明を表示しています。

Use when enhancing, upscaling, restoring, denoising, sharpening, deinterlacing, stabilizing, motion-deblurring, colorizing, SDR-to-HDR converting, or frame-rate/slow-motion converting video (and secondarily images) with Topaz Labs — whether cleaning up AI-generated video, compressed UGC, or old archival footage, or building a generate-low-res-then-upscale delivery pipeline. Covers choosing the right named Topaz model for a specific footage problem, setting parameters, driving the Topaz Platform (Video/Image) REST API's async job lifecycle, judging when enhancement helps versus when it introduces artifacts (over-smoothing, temporal shimmer, face hallucination), and QA of enhanced output. Do not use for originating new video content, non-Topaz upscalers, or purely editorial cuts.

日本語の概要は準備中です。原文の説明を表示しています。

Provider-independent quality assurance for AI-generated and AI-assisted media. Use when reviewing, accepting, revising, or reporting on images, video, audio, avatars, ads, product content, social clips, explainers, localization, mixed-source edits, captions, accessibility, provenance, model metadata, safety/policy, and delivery readiness.

日本語の概要は準備中です。原文の説明を表示しています。

Processes environmental DNA metabarcoding data from raw amplicon reads to species occurrence tables using OBITools3, DADA2, and taxonomic assignment against BOLD, MIDORI2, or MitoFish databases. Handles COI, 12S, rbcL, and ITS barcode regions with primer removal, denoising, chimera detection, and contamination filtering via decontam. Includes occupancy modeling (occumb) for detection probability correction. Use when analyzing eDNA from water, soil, or bulk samples for biodiversity monitoring. Not for 16S human microbiome (see microbiome/amplicon-processing).

日本語の概要は準備中です。原文の説明を表示しています。

Normalize read-depth copy-ratio profiles and segment them into copy-number regions using circular binary segmentation (CBS, DNAcopy), hidden Markov models, HaarSeg, and fused-lasso methods. Covers GC-content, mappability, and replication-timing (wave-artifact) bias correction, panel-of-normals/PCA denoising, diploid-baseline centering, and algorithm selection by sequencing depth and event size. Use when choosing a segmentation algorithm, correcting depth bias, diagnosing oversegmentation or a mis-centered baseline, tuning CBS or HMM parameters, or understanding why a downstream CNV caller produced fragmented or shifted segments.

日本語の概要は準備中です。原文の説明を表示しています。

风险投资人 / 早期投资判断(GP + Principal — Deal sourcing / 尽调 / 估值与 term sheet / 投后服务 / 退出 + LP 关系与 fundraising — 涵盖 US 美元基金 + 国内 RMB / 美元基金) (Venture capital / early-stage investor — 风险投资人(GP / Partner / Principal)的早期投资判断与基金运营实战) Master OS — automated mastery of Venture capital / early-stage investor — 风险投资人(GP / Partner / Principal)的早期投资判断与基金运营实战: top builders' mental models, tool stack, current workflows, jargon, and where to keep up. Trigger this skill when the user works on Venture capital / early-stage investor — 风险投资人(GP / Partner / Principal)的早期投资判断与基金运营实战 problems and wants industry-grade thinking, tool selection, or workflow guidance. 触发词：「VC」「venture capital」「风险投资」「early stage」「天使投资」

日本語の概要は準備中です。原文の説明を表示しています。

亚马逊管理之道 (亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 > 良好意图(Good intentions don't work, mechanisms do:问题不能靠『下次更努力』修复,要装一个带检查闭环的自我强化流程) ⇄ 可控输入指标 vs 滞后输出指标(管你能控制的 input 如选品/价格/在库/配送速度,而非 revenue/股价这类滞后又不可控的 output) ⇄ 长期主义 vs 季度业绩(Day 1、willing to be misunderstood、用现金流+飞轮长期投入,宁可牺牲短期利润) ⇄ 客户执念 vs 竞争对手执念(working backwards 从客户倒推,而非从竞品或『我们能造什么』正推) ⇄ 叙事备忘录 vs PPT(6-pager + 开会前静默阅读、动手前先写 PR/FAQ;写作逼出清晰思考,禁 PowerPoint) ⇄ 单线程负责人/两个披萨团队 vs 协调税(separable、autonomous、one owner per initiative,砍掉跨团队依赖) ⇄ 高标准可学习可传递 vs 与生俱来(insist on the highest standards + Bar Raiser 招聘门,标准是 domain-specific 且能教的) ⇄ 节俭催生创造力 vs 血汗文化(frugality/约束驱动发明 —— 但 frugality + 高压 bar + URA 强制淘汰 = 文化阴暗面批判) ⇄ 两类决策(Type 1 不可逆/单向门 慎重 vs Type 2 可逆/双向门 高判断力个人快速决策,别用重流程拖慢))**; (b) 核心机制(mechanisms,本行的『工具栈』其实是一套运营机制而非软件) — Leadership Principles(14 条→2021 增至 16 条,是一套运营语言和决策仲裁器)、Working Backwards(从客户倒推:动手前先写新闻稿+常见问答 PR/FAQ)、叙事备忘录(6-pager narrative / 1-pager + silent reading 静默阅读、禁 PPT)、Weekly Business Review(WBR + metrics deck 指标看板)、input/output metrics(可控输入指标体系、DMAIC 式指标选择)、年度规划(OP1/OP2 + S-Team goals)、Bar Raiser(招聘机制,独立于用人经理的抬杠者拥有一票否决)、Two-Pizza Team / Single-Threaded Leader STL / separable teams、Correction of Errors(COE 事故复盘 + 5 Whys 五问法)、Andon Cord(安灯绳,借自丰田,一线可拉停)、Flywheel(飞轮:低价→更多客户→更多卖家→更多选品→更低成本结构→更低价)、Type 1/Type 2(单向门/双向门决策分级)、Regret Minimization Framework(遗憾最小化,贝索斯创业决策法); (c) 心智模型层 — customer obsession(客户执念是所有 LP 之首)、long-term thinking / Day 1(第二天就是停滞衰亡)、invent and simplify、ownership(主人翁,不说 that's not my job)、bias for action(可逆决策就快,speed matters)、disagree and commit(充分反对后即便不同意也全力执行)、frugality、dive deep(深入细节、不靠代理指标脱离一线)、think big、are right a lot(用强判断力和证伪自己的能力多做对的判断)、earn trust、deliver results; (d) 工作流/SOP — 用亚马逊方式发起一个新产品/业务(先写 PR/FAQ→评审→倒推着造)、如何跑一场 WBR、如何写和评审一份 6-pager(叙事流程 + 静默阅读)、Bar Raiser 招聘 loop、年度规划(OP1/OP2→S-Team goals→输入指标追踪)、事故后的 Correction of Errors; (e) 知识正典(en-primary,极其丰富且可取一手) — 贝索斯致股东信 1997-2021(1997 首封是奠基文本,每年附在信末;Day 1、遗憾最小化、long term)、《Working Backwards》Colin Bryar & Bill Carr(2021,运营机制圣经)、《The Everything Store》Brad Stone(2013,公司史)、《Amazon Unbound》Brad Stone(2021,权力与阴暗面续作)、《Invent and Wander》贝索斯文集(2020)、《The Amazon Way》/《Think Like Amazon》John Rossman(前亚马逊高管)、Amazon 官方 Leadership Principles 页(amazon.jobs,一手)、HBR『The Institutional Yes』(2007 贝索斯访谈); (f) 行业大佬/figures — Jeff Bezos(创始人,源头教义)、Andy Jassy(现任 CEO,OS 超越创始人的证据 + AWS 缔造者)、Colin Bryar(前贝索斯影子/TPM,《Working Backwards》作者)、Bill Carr(前数字媒体 VP,《Working Backwards》作者)、Jeff Wilke(前全球消费者 CEO,运营架构师)、John Rossman(前亚马逊、机制布道者/顾问)、Brad Stone(记者/编年史作者,批判性外部视角); (g) 争议/批判(必须保留,不能洗白) — 文化阴暗面(NYT 2015『Inside Amazon: Wrestling Big Ideas in a Bruising Workplace』揭露高压职场)、仓储与一线劳工争议、URA(unregretted attrition 强制淘汰)与 stack-ranking 的残酷、frugality + 高 bar = 燃尽(burnout);机制能否迁出亚马逊(cargo-culting:在初创或非科技公司照搬 PR/FAQ/输入指标/Bar Raiser 常失败);是贝索斯个人天才(personality)还是制度化机制(institution)—— OS 在贝索斯卸任后于 Jassy 治下延续,是机制派的证据; (h) 流派/思想谱系 — **信徒/机制布道派(Bryar & Carr《Working Backwards》+ 前亚马逊 operator 顾问圈,信 mechanisms 可移植、任何公司可安装)** vs **批判派(Brad Stone《Amazon Unbound》+ NYT + 劳工视角,认为 OS 与高淘汰的残酷机器不可分割,不该被浪漫化)** vs **情境/规模怀疑派(机制之所以有效是因为亚马逊特定的规模/现金流/创始人权力,照搬到小公司=cargo cult)** vs **创始人中心 vs 制度中心之争(是贝索斯个人 vs 可传承的机制)**。不含: 在亚马逊开店卖货/选品/PPC/FBA 的卖家运营(=cross-border-ecommerce)、AWS 云技术架构与运维、通用 MBA 管理理论泛泛而谈、把普通商业常识包装成『亚马逊独家秘诀』。) Master OS — automated mastery of 亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 >

日本語の概要は準備中です。原文の説明を表示しています。

Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Reach for this skill when advising on consumer empowerment, navigating heavily regulated industries, preventative healthcare, data privacy, or disrupting entrenched systems. Use this when the user is dealing with misaligned industry incentives, facing regulatory hurdles, building a consumer-research flywheel, or managing a team through a post-launch 'trough of sorrow'. Apply her principles of 'speaking with data', treating users as partners, and pushing for decade-long systemic change from the outside.

日本語の概要は準備中です。原文の説明を表示しています。